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Author: Bengt Samuelsson
Publisher: Lippincott Williams & Wilkins
Published: 1982
Total Pages: 365
ISBN-13: 9780890047415
DOWNLOAD EBOOKDownload or read book Leukotrienes and Other Lipoxygenase Products written by Bengt Samuelsson and published by Lippincott Williams & Wilkins. This book was released on 1982 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author: Edwin N. Frankel
Publisher: Elsevier
Published: 2014-01-23
Total Pages: 487
ISBN-13: 085709792X
DOWNLOAD EBOOKIn this second edition, Edwin Frankel has updated and extended his now well-known book Lipid oxidation which has come to be regarded as the standard work on the subject since the publication of the first edition seven years previously. His main objective is to develop the background necessary for a better understanding of what factors should be considered, and what methods and lipid systems should be employed, to achieve suitable evaluation and control of lipid oxidation in complex foods and biological systems. The oxidation of unsaturated fatty acids is one of the most fundamental reactions in lipid chemistry. When unsaturated lipids are exposed to air, the complex, volatile oxidation compounds that are formed cause rancidity. This decreases the quality of foods that contain natural lipid components as well as foods in which oils are used as ingredients. Furthermore, products of lipid oxidation have been implicated in many vital biological reactions, and evidence has accumulated to show that free radicals and reactive oxygen species participate in tissue injuries and in degenerative disease. Although there have been many significant advances in this challenging field, many important problems remain unsolved. This second edition of Lipid oxidation follows the example of the first edition in offering a summary of the many unsolved problems that need further research. The need to understand lipid oxidation is greater than ever with the increased interest in long-chain polyunsaturated fatty acids, the reformulation of oils to avoid hydrogenation and trans fatty acids, and the enormous attention given to natural phenolic antioxidants, including flavonoids and other phytochemicals.
Download or read book Lipid Oxidation written by Edwin N. Frankel and published by Elsevier. This book was released on 2014-01-23 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this second edition, Edwin Frankel has updated and extended his now well-known book Lipid oxidation which has come to be regarded as the standard work on the subject since the publication of the first edition seven years previously. His main objective is to develop the background necessary for a better understanding of what factors should be considered, and what methods and lipid systems should be employed, to achieve suitable evaluation and control of lipid oxidation in complex foods and biological systems. The oxidation of unsaturated fatty acids is one of the most fundamental reactions in lipid chemistry. When unsaturated lipids are exposed to air, the complex, volatile oxidation compounds that are formed cause rancidity. This decreases the quality of foods that contain natural lipid components as well as foods in which oils are used as ingredients. Furthermore, products of lipid oxidation have been implicated in many vital biological reactions, and evidence has accumulated to show that free radicals and reactive oxygen species participate in tissue injuries and in degenerative disease. Although there have been many significant advances in this challenging field, many important problems remain unsolved. This second edition of Lipid oxidation follows the example of the first edition in offering a summary of the many unsolved problems that need further research. The need to understand lipid oxidation is greater than ever with the increased interest in long-chain polyunsaturated fatty acids, the reformulation of oils to avoid hydrogenation and trans fatty acids, and the enormous attention given to natural phenolic antioxidants, including flavonoids and other phytochemicals.
Author: Stanley Crooke
Publisher: Academic Press
Published: 2012-12-02
Total Pages: 313
ISBN-13: 0323156533
DOWNLOAD EBOOKLipoxygenases and Their Products provides a cogent summary of the advances in understanding lipoxygenases and their products, emphasizing their pharmacology and pathophysiology; regulation and structure; physiological role; and receptors and receptor antagonists. This text also reviews the literature where specific receptor antagonists (as opposed to enzymatic inhibitors) have been used to characterize the pharmacologic action and the pathophysiologic roles of some of lipoxygenase products of arachidonic acid metabolism. This book is organized into 11 chapters and begins with an overview of the biochemical, pharmacological, and pathophysiological aspects of 5-lipoxygenase products of arachidonic acid metabolism in the respiratory, cardiovascular, renal, gastrointestinal, and central nervous systems. The discussion then shifts to human 5-lipoxygenase, emphasizing this enzyme purification, stimulatory factors, and membrane translocation. The reader is methodically introduced to 5-lipoxygenase activity in rats and pigs; the potential and therapeutic value of 5-lipoxygenase inhibitors; the distribution of 15-lipoxygenase in cells or tissues; and products formed through the 15-lipoxygenase pathway. This book also considers lipoxins and third-generation peptidoleukotriene receptor antagonists, and then concludes with a summary of the physiological and pathophysiological effects of leukotrienes and lipoxins in a variety of organs. This book is of interest to scientists interested in arachidonic acid and its metabolites, to scientists engaged in drug discovery-and-development activities in academia and the pharmaceutical industry, and to clinicians interested in diseases associated with leukotrienes and related products.
Download or read book Lipoxygenases and Their Products written by Stanley Crooke and published by Academic Press. This book was released on 2012-12-02 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lipoxygenases and Their Products provides a cogent summary of the advances in understanding lipoxygenases and their products, emphasizing their pharmacology and pathophysiology; regulation and structure; physiological role; and receptors and receptor antagonists. This text also reviews the literature where specific receptor antagonists (as opposed to enzymatic inhibitors) have been used to characterize the pharmacologic action and the pathophysiologic roles of some of lipoxygenase products of arachidonic acid metabolism. This book is organized into 11 chapters and begins with an overview of the biochemical, pharmacological, and pathophysiological aspects of 5-lipoxygenase products of arachidonic acid metabolism in the respiratory, cardiovascular, renal, gastrointestinal, and central nervous systems. The discussion then shifts to human 5-lipoxygenase, emphasizing this enzyme purification, stimulatory factors, and membrane translocation. The reader is methodically introduced to 5-lipoxygenase activity in rats and pigs; the potential and therapeutic value of 5-lipoxygenase inhibitors; the distribution of 15-lipoxygenase in cells or tissues; and products formed through the 15-lipoxygenase pathway. This book also considers lipoxins and third-generation peptidoleukotriene receptor antagonists, and then concludes with a summary of the physiological and pathophysiological effects of leukotrienes and lipoxins in a variety of organs. This book is of interest to scientists interested in arachidonic acid and its metabolites, to scientists engaged in drug discovery-and-development activities in academia and the pharmaceutical industry, and to clinicians interested in diseases associated with leukotrienes and related products.
Author: Jeffrey Drazen
Publisher: CRC Press
Published: 2016-04-19
Total Pages: 520
ISBN-13: 0824746368
DOWNLOAD EBOOKFive-Lipoxygenase Products in Asthma offers an authoritative examination of the biochemistry, basic pharmacology, and clinical pharmacology of the leukotrienes with special emphasis on their role in asthma. A critical reference for every asthma researcher and clinician, Five-Lipoxygenase Products in Asthma highlights agents and products
Download or read book Five-Lipoxygenase Products in Asthma written by Jeffrey Drazen and published by CRC Press. This book was released on 2016-04-19 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Five-Lipoxygenase Products in Asthma offers an authoritative examination of the biochemistry, basic pharmacology, and clinical pharmacology of the leukotrienes with special emphasis on their role in asthma. A critical reference for every asthma researcher and clinician, Five-Lipoxygenase Products in Asthma highlights agents and products
Author: Joshua Rokach
Publisher: Elsevier Publishing Company
Published: 1989
Total Pages: 560
ISBN-13:
DOWNLOAD EBOOKImportant advances have been made in the chemistry and biochemistry of the leukotrienes mainly as a result of the development of new biophysical and biochemical methodologies. The extraordinary effort of many scientists and the interactions of many scientific disciplines has created a vast amount of data and information and, with it, the need for a book addressing all aspects of this multidisciplinary field. This book has been written to respond to that need. It comprises six chapters which together provide a cohesive interdisciplinary coverage of the field, from the organic, analytical aspect to the biological sciences. Among the many subjects covered are many aspects of the leukotriene field which have not been covered in detail before, i.e. the numerous methodologies employed in the detection, localization and quantitation of lipoxygenase products; the role of leukotrienes in human disease states; leukotriene antagonists and lipoxygenase inhibitors, and potential therapeutic agents. The book brings together a wide variety of material to give a valuable overview of this important subject.
Download or read book Leukotrienes and Lipoxygenases written by Joshua Rokach and published by Elsevier Publishing Company. This book was released on 1989 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Important advances have been made in the chemistry and biochemistry of the leukotrienes mainly as a result of the development of new biophysical and biochemical methodologies. The extraordinary effort of many scientists and the interactions of many scientific disciplines has created a vast amount of data and information and, with it, the need for a book addressing all aspects of this multidisciplinary field. This book has been written to respond to that need. It comprises six chapters which together provide a cohesive interdisciplinary coverage of the field, from the organic, analytical aspect to the biological sciences. Among the many subjects covered are many aspects of the leukotriene field which have not been covered in detail before, i.e. the numerous methodologies employed in the detection, localization and quantitation of lipoxygenase products; the role of leukotrienes in human disease states; leukotriene antagonists and lipoxygenase inhibitors, and potential therapeutic agents. The book brings together a wide variety of material to give a valuable overview of this important subject.
Author: G. Velo
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 390
ISBN-13: 1468478419
DOWNLOAD EBOOKDownload or read book Drugs Affecting Leukotrienes and Other Eicosanoid Pathways written by G. Velo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Prostaglandin and Thromboxane Research: Leukotrines and other lipoxygenase products written by Bengt Samuelsson and published by . This book was released on 1982 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Leukotrienes and Prostanoids in Health and Disease written by Zvi Naor and published by . This book was released on 1986 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author: Ahmed Al-Harrasi
Publisher: Elsevier
Published: 2018-09-19
Total Pages: 164
ISBN-13: 0081024487
DOWNLOAD EBOOKExhibiting a wealth of interesting activities and novel structures, Boswellic acid and the other terpenoids of the genus Boswellia (from which frankincense is derived) are a growing source of interest for the natural product drug discovery community. Chemistry and Bioactivity of Boswellic Acids and Other Terpenoids of the Genus Boswellia presents, in a single volume for the first time, key research into their structures, synthesis and potential as starting points for the development of medicinal agents. Drawing on the authors’ expert knowledge, this volume is an interesting insight into the identification of novel compounds from endemic plant sources, and is a useful tool for all researchers involved in the discovery and development of bioactive structures from natural products. Collates key information on the underlying chemistry and activities of bioactive agents from the Boswellia species Highlights techniques applicable to the study of natural products across the globe Provides insights into the assessment of medicinal natural products with high economic potential
Download or read book Chemistry and Bioactivity of Boswellic Acids and Other Terpenoids of the Genus Boswellia written by Ahmed Al-Harrasi and published by Elsevier. This book was released on 2018-09-19 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exhibiting a wealth of interesting activities and novel structures, Boswellic acid and the other terpenoids of the genus Boswellia (from which frankincense is derived) are a growing source of interest for the natural product drug discovery community. Chemistry and Bioactivity of Boswellic Acids and Other Terpenoids of the Genus Boswellia presents, in a single volume for the first time, key research into their structures, synthesis and potential as starting points for the development of medicinal agents. Drawing on the authors’ expert knowledge, this volume is an interesting insight into the identification of novel compounds from endemic plant sources, and is a useful tool for all researchers involved in the discovery and development of bioactive structures from natural products. Collates key information on the underlying chemistry and activities of bioactive agents from the Boswellia species Highlights techniques applicable to the study of natural products across the globe Provides insights into the assessment of medicinal natural products with high economic potential
Author: Royal College of Surgeons of England, Institute of
Publisher:
Published:
Total Pages: 367
ISBN-13: 9780835770811
DOWNLOAD EBOOKDownload or read book Leukotrienes and Other Lipoxygenase Products written by Royal College of Surgeons of England, Institute of and published by . This book was released on with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt:
