Liver Metabolism and Diseases

Liver Metabolism and Diseases

Author: Joseph Curtis

Publisher: Murphy & Moore Publishing

Published: 2023-09-26

Total Pages: 0

ISBN-13: 9781639877850

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Liver is an integral part of the process of metabolism. It helps in the preservation and regulation of the lipid and glucose levels in the body, as well as in energy metabolism. The most common metabolic diseases which can affect the liver are Wilson disease, hereditary hemochromatosis, and Alpha-I antitrypsin deficiency (AATD). Some of the other types of disorders which affect the liver are infections, immune system issues, cancers, and heritable conditions. One of the upcoming methods of study which is used to study the cell metabolism within the liver is metabolomics. It refers to the scientific study of chemical processes involving metabolites, the small molecule substrates, intermediates, and products of cell metabolism. Metabolomics has a very high potential to detect biomarker candidates for the prospective advancement of new therapeutics. The book aims to shed light on some of the unexplored aspects of liver metabolism and the recent researches in this field with respect to liver diseases. It will provide comprehensive knowledge to both medical students and professionals.


Book Synopsis Liver Metabolism and Diseases by : Joseph Curtis

Download or read book Liver Metabolism and Diseases written by Joseph Curtis and published by Murphy & Moore Publishing. This book was released on 2023-09-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver is an integral part of the process of metabolism. It helps in the preservation and regulation of the lipid and glucose levels in the body, as well as in energy metabolism. The most common metabolic diseases which can affect the liver are Wilson disease, hereditary hemochromatosis, and Alpha-I antitrypsin deficiency (AATD). Some of the other types of disorders which affect the liver are infections, immune system issues, cancers, and heritable conditions. One of the upcoming methods of study which is used to study the cell metabolism within the liver is metabolomics. It refers to the scientific study of chemical processes involving metabolites, the small molecule substrates, intermediates, and products of cell metabolism. Metabolomics has a very high potential to detect biomarker candidates for the prospective advancement of new therapeutics. The book aims to shed light on some of the unexplored aspects of liver metabolism and the recent researches in this field with respect to liver diseases. It will provide comprehensive knowledge to both medical students and professionals.

Liver Metabolism and Fatty Liver Disease

Liver Metabolism and Fatty Liver Disease

Author: Oren Tirosh

Publisher: CRC Press

Published: 2021-03-30

Total Pages: 0

ISBN-13: 9780367659080

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About 30% of the general population suffers from non-alcoholic fatty liver disease, and the incidence of more serious fatty liver disorders increases with obesity. This volume discusses the current understanding of the development of fatty liver disease and reviews its clinical aspects. Expert contributors discuss the absorption and metabolism o


Book Synopsis Liver Metabolism and Fatty Liver Disease by : Oren Tirosh

Download or read book Liver Metabolism and Fatty Liver Disease written by Oren Tirosh and published by CRC Press. This book was released on 2021-03-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: About 30% of the general population suffers from non-alcoholic fatty liver disease, and the incidence of more serious fatty liver disorders increases with obesity. This volume discusses the current understanding of the development of fatty liver disease and reviews its clinical aspects. Expert contributors discuss the absorption and metabolism o

Metabolism and Metabolomics of Liver in Health and Disease

Metabolism and Metabolomics of Liver in Health and Disease

Author: Walter Wahli

Publisher: MDPI

Published: 2021-02-19

Total Pages: 268

ISBN-13: 303943635X

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Women and men have probably never been concerned as much by their health as during this COVID-19 pandemic. In this context, lifestyle habits continue to be promoted as allies for daily prevention against diseases. This is valid also for metabolic diseases, among which many affect the liver and are risk factors for aggravating the disease course of COVID-19. In fact, liver diseases are currently a major global health problem. There is a huge range of liver diseases and non-alcoholic fatty liver disease (NAFLD) is the most common chronic hepatic condition, which in some patients progresses to cirrhosis and liver cancer. Currently, substantial efforts are being made to better understand NAFLD, especially, because there is no U.S. Food and Drug Administration (FDA)-approved pharmacological therapy. To explore this disease, metabolomics is the most recently developed omics technology after genomics, transcriptomics, and proteomics. Metabolomics is the large-scale analysis of molecules, known as metabolites that are intermediate or end products of metabolism found within cells, tissues, and biofluids. This technology has a very high potential to identify biomarker candidates for the future development of new therapeutics. The book features articles that address metabolomics technology and its use to document different liver functions and dysfunctions, with a major focus on NAFLD.


Book Synopsis Metabolism and Metabolomics of Liver in Health and Disease by : Walter Wahli

Download or read book Metabolism and Metabolomics of Liver in Health and Disease written by Walter Wahli and published by MDPI. This book was released on 2021-02-19 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Women and men have probably never been concerned as much by their health as during this COVID-19 pandemic. In this context, lifestyle habits continue to be promoted as allies for daily prevention against diseases. This is valid also for metabolic diseases, among which many affect the liver and are risk factors for aggravating the disease course of COVID-19. In fact, liver diseases are currently a major global health problem. There is a huge range of liver diseases and non-alcoholic fatty liver disease (NAFLD) is the most common chronic hepatic condition, which in some patients progresses to cirrhosis and liver cancer. Currently, substantial efforts are being made to better understand NAFLD, especially, because there is no U.S. Food and Drug Administration (FDA)-approved pharmacological therapy. To explore this disease, metabolomics is the most recently developed omics technology after genomics, transcriptomics, and proteomics. Metabolomics is the large-scale analysis of molecules, known as metabolites that are intermediate or end products of metabolism found within cells, tissues, and biofluids. This technology has a very high potential to identify biomarker candidates for the future development of new therapeutics. The book features articles that address metabolomics technology and its use to document different liver functions and dysfunctions, with a major focus on NAFLD.

Liver Metabolism and Fatty Liver Disease

Liver Metabolism and Fatty Liver Disease

Author: Oren Tirosh

Publisher: CRC Press

Published: 2014-08-27

Total Pages: 344

ISBN-13: 1482212455

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Nonalcoholic fatty liver disease is one of the most common liver diseases worldwide affecting patients from all ages, races, and ethnic backgrounds. It comprises a spectrum of hepatic pathology ranging from simple steatosis, in which there is an increase of fat accumulation in hepatocytes, to nonalcoholic steatohepatitis and cirrhosis. The significant prevalence of this disease—between 15 and 45 percent of the general population—means that it contributes to an increased burden of ill health both today and in the future. Liver Metabolism and Fatty Liver Disease addresses the current understanding of the development of nonalcoholic fatty liver disease as well as the clinical aspects of the disease by examining the current knowledge surrounding metabolism in the liver. The book discusses various topics including the involvement of oxidative stress, metabolic effects, and inflammation as well as the effect of nutrition on the development and progression of the disease.


Book Synopsis Liver Metabolism and Fatty Liver Disease by : Oren Tirosh

Download or read book Liver Metabolism and Fatty Liver Disease written by Oren Tirosh and published by CRC Press. This book was released on 2014-08-27 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nonalcoholic fatty liver disease is one of the most common liver diseases worldwide affecting patients from all ages, races, and ethnic backgrounds. It comprises a spectrum of hepatic pathology ranging from simple steatosis, in which there is an increase of fat accumulation in hepatocytes, to nonalcoholic steatohepatitis and cirrhosis. The significant prevalence of this disease—between 15 and 45 percent of the general population—means that it contributes to an increased burden of ill health both today and in the future. Liver Metabolism and Fatty Liver Disease addresses the current understanding of the development of nonalcoholic fatty liver disease as well as the clinical aspects of the disease by examining the current knowledge surrounding metabolism in the liver. The book discusses various topics including the involvement of oxidative stress, metabolic effects, and inflammation as well as the effect of nutrition on the development and progression of the disease.

Metabolism and Nutrition in Liver Disease

Metabolism and Nutrition in Liver Disease

Author: E. Holm

Publisher: Springer Science & Business Media

Published: 1985-10-31

Total Pages: 430

ISBN-13: 9780852009079

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Book Synopsis Metabolism and Nutrition in Liver Disease by : E. Holm

Download or read book Metabolism and Nutrition in Liver Disease written by E. Holm and published by Springer Science & Business Media. This book was released on 1985-10-31 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Metabolic Aspects of Chronic Liver Disease

Metabolic Aspects of Chronic Liver Disease

Author: Ami Schattner

Publisher: Nova Publishers

Published: 2008

Total Pages: 392

ISBN-13: 9781600212017

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This book discusses in detail new aspects of the metabolic basis of important chronic liver diseases. Entities such as non-alcoholic fatty liver disease (fatty liver and Non-Alcoholic SteatoHepatitis -- NASH), diabeties in chronic hepetitis C, hemochromatosis, Wilson's disease, Gaucher disease, porphyria, as well as liver cirrhosis and its metabolic consequences will be discussed in detail. These clinical conditions are highly prevalent and affect millions of patients in the USA and world-wide. For example, non-alcoholic fatty liver disease is the most common cause of elevated liver enzymes in the general population. This field has been practically transformed over the last few years, with many new insights gained, regarding both pathogenesis and effective novel treatments.


Book Synopsis Metabolic Aspects of Chronic Liver Disease by : Ami Schattner

Download or read book Metabolic Aspects of Chronic Liver Disease written by Ami Schattner and published by Nova Publishers. This book was released on 2008 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses in detail new aspects of the metabolic basis of important chronic liver diseases. Entities such as non-alcoholic fatty liver disease (fatty liver and Non-Alcoholic SteatoHepatitis -- NASH), diabeties in chronic hepetitis C, hemochromatosis, Wilson's disease, Gaucher disease, porphyria, as well as liver cirrhosis and its metabolic consequences will be discussed in detail. These clinical conditions are highly prevalent and affect millions of patients in the USA and world-wide. For example, non-alcoholic fatty liver disease is the most common cause of elevated liver enzymes in the general population. This field has been practically transformed over the last few years, with many new insights gained, regarding both pathogenesis and effective novel treatments.

Hepatic De Novo Lipogenesis and Regulation of Metabolism

Hepatic De Novo Lipogenesis and Regulation of Metabolism

Author: James M. Ntambi

Publisher: Springer

Published: 2015-12-17

Total Pages: 305

ISBN-13: 3319250655

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The liver is the largest solid vital organ in mammals that supports other organ in the body in some facet. This book synthesizes all the primary and relevant metabolic information that one needs to review to understand the complex and diverse role of the liver in metabolism. With the current epidemic of metabolic diseases, it is of immediate importance to understand the contribution of the liver in health and its role in the development of impaired metabolic regulation. This book covers the many studies that have unmasked important roles that proteins expressed in the liver play in the development of or protection from metabolic diseases. One of the major metabolic functions of the liver is to carry out de novo lipogenesis, which is the metabolic pathway that allows the conversion of excess carbohydrates into fatty acids. The process of de novo lipogenesis is covered in depth within this volume. The book is an important contribution to the vast literature and ongoing research on liver function.


Book Synopsis Hepatic De Novo Lipogenesis and Regulation of Metabolism by : James M. Ntambi

Download or read book Hepatic De Novo Lipogenesis and Regulation of Metabolism written by James M. Ntambi and published by Springer. This book was released on 2015-12-17 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: The liver is the largest solid vital organ in mammals that supports other organ in the body in some facet. This book synthesizes all the primary and relevant metabolic information that one needs to review to understand the complex and diverse role of the liver in metabolism. With the current epidemic of metabolic diseases, it is of immediate importance to understand the contribution of the liver in health and its role in the development of impaired metabolic regulation. This book covers the many studies that have unmasked important roles that proteins expressed in the liver play in the development of or protection from metabolic diseases. One of the major metabolic functions of the liver is to carry out de novo lipogenesis, which is the metabolic pathway that allows the conversion of excess carbohydrates into fatty acids. The process of de novo lipogenesis is covered in depth within this volume. The book is an important contribution to the vast literature and ongoing research on liver function.

Liver Pathophysiology

Liver Pathophysiology

Author: Pablo Muriel

Publisher: Academic Press

Published: 2017-03-02

Total Pages: 914

ISBN-13: 0128043210

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Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies. Presents the most recent advances in hepatology, with a special focus on the role of oxidative stress in liver injury. Provides in vivo and in vitro models to study human liver pathology. Explains the beneficial effects of antioxidants on liver diseases. Contains the most recent and modern treatments of hepatic pathologies, including, but not limited to, stem cells repopulation, gene therapy and liver transplantation.


Book Synopsis Liver Pathophysiology by : Pablo Muriel

Download or read book Liver Pathophysiology written by Pablo Muriel and published by Academic Press. This book was released on 2017-03-02 with total page 914 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies. Presents the most recent advances in hepatology, with a special focus on the role of oxidative stress in liver injury. Provides in vivo and in vitro models to study human liver pathology. Explains the beneficial effects of antioxidants on liver diseases. Contains the most recent and modern treatments of hepatic pathologies, including, but not limited to, stem cells repopulation, gene therapy and liver transplantation.

Metabolism and Metabolomics of Liver in Health and Disease

Metabolism and Metabolomics of Liver in Health and Disease

Author: Walter Wahli

Publisher:

Published: 2021

Total Pages: 268

ISBN-13: 9783039436361

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Women and men have probably never been concerned as much by their health as during this COVID-19 pandemic. In this context, lifestyle habits continue to be promoted as allies for daily prevention against diseases. This is valid also for metabolic diseases, among which many affect the liver and are risk factors for aggravating the disease course of COVID-19. In fact, liver diseases are currently a major global health problem. There is a huge range of liver diseases and non-alcoholic fatty liver disease (NAFLD) is the most common chronic hepatic condition, which in some patients progresses to cirrhosis and liver cancer. Currently, substantial efforts are being made to better understand NAFLD, especially, because there is no U.S. Food and Drug Administration (FDA)-approved pharmacological therapy. To explore this disease, metabolomics is the most recently developed omics technology after genomics, transcriptomics, and proteomics. Metabolomics is the large-scale analysis of molecules, known as metabolites that are intermediate or end products of metabolism found within cells, tissues, and biofluids. This technology has a very high potential to identify biomarker candidates for the future development of new therapeutics. The book features articles that address metabolomics technology and its use to document different liver functions and dysfunctions, with a major focus on NAFLD.


Book Synopsis Metabolism and Metabolomics of Liver in Health and Disease by : Walter Wahli

Download or read book Metabolism and Metabolomics of Liver in Health and Disease written by Walter Wahli and published by . This book was released on 2021 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Women and men have probably never been concerned as much by their health as during this COVID-19 pandemic. In this context, lifestyle habits continue to be promoted as allies for daily prevention against diseases. This is valid also for metabolic diseases, among which many affect the liver and are risk factors for aggravating the disease course of COVID-19. In fact, liver diseases are currently a major global health problem. There is a huge range of liver diseases and non-alcoholic fatty liver disease (NAFLD) is the most common chronic hepatic condition, which in some patients progresses to cirrhosis and liver cancer. Currently, substantial efforts are being made to better understand NAFLD, especially, because there is no U.S. Food and Drug Administration (FDA)-approved pharmacological therapy. To explore this disease, metabolomics is the most recently developed omics technology after genomics, transcriptomics, and proteomics. Metabolomics is the large-scale analysis of molecules, known as metabolites that are intermediate or end products of metabolism found within cells, tissues, and biofluids. This technology has a very high potential to identify biomarker candidates for the future development of new therapeutics. The book features articles that address metabolomics technology and its use to document different liver functions and dysfunctions, with a major focus on NAFLD.

Neonatal and Pediatric Liver and Metabolic Diseases

Neonatal and Pediatric Liver and Metabolic Diseases

Author: Manoj K. Ghoda

Publisher: Springer Nature

Published: 2020-12-05

Total Pages: 266

ISBN-13: 9811592314

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This book is written to simplify complex topics of neonatal and pediatric liver and metabolic diseases which are encountered by clinicians on a day to day basis. Neonatal and early pediatric liver diseases are very much different from adult liver diseases. Most of them are either structural diseases or genetically modulated metabolic disorders affecting liver. They all look same; however the underlying etiology could be quite different. This book thoroughly covers various neonatal and pediatric liver and metabolic diseases through a unique clinical case based approach via a vast clinical experience of the author. The book presents more than 50 unique cases and presents real life learning scenario with various examples facilitating better understanding of the disease and the ways to analyze it. The book uses a simple language and presents line diagrams and algorithms facilitating learning. This book shall be a valuable resource for practicing general pediatricians, pediatric residents and gastroenterologists with involvement in pediatric liver and liver related metabolic diseases.


Book Synopsis Neonatal and Pediatric Liver and Metabolic Diseases by : Manoj K. Ghoda

Download or read book Neonatal and Pediatric Liver and Metabolic Diseases written by Manoj K. Ghoda and published by Springer Nature. This book was released on 2020-12-05 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is written to simplify complex topics of neonatal and pediatric liver and metabolic diseases which are encountered by clinicians on a day to day basis. Neonatal and early pediatric liver diseases are very much different from adult liver diseases. Most of them are either structural diseases or genetically modulated metabolic disorders affecting liver. They all look same; however the underlying etiology could be quite different. This book thoroughly covers various neonatal and pediatric liver and metabolic diseases through a unique clinical case based approach via a vast clinical experience of the author. The book presents more than 50 unique cases and presents real life learning scenario with various examples facilitating better understanding of the disease and the ways to analyze it. The book uses a simple language and presents line diagrams and algorithms facilitating learning. This book shall be a valuable resource for practicing general pediatricians, pediatric residents and gastroenterologists with involvement in pediatric liver and liver related metabolic diseases.