Mechanism of Action of Antimicrobial and Antitumor Agents

Mechanism of Action of Antimicrobial and Antitumor Agents

Author: J. F. Snell

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 752

ISBN-13: 3642463045

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This volume is the third in the series devoted to Antibiotics initiated by Springer Verlag in 1967. The first two volumes were devoted to the Mode of Action of Antibiotics and Biogenesis, respectively and were received graciously. During the intervening years these two works have been used often by research workers and students alike and have been quoted extensively. Although a number of other excellent treatises on antibiotics have appeared, the Springer series has set a standard for thoroughness and quality that meets the need of the scientific community. It is against this background that the present Editors set about the preparation of a third volume in the Series on Antibiotics. Since the appearance of Volume I, also dealing with Mechanism of Action, tremendous strides have been made in the depth and breadth of our knowledge of molecular biology, microbial chemistry and molecular pharmacology and of their direct application to studies on the mode of action of drugs. The field of molecular biology itself was in its relative infancy during the preceding decade and the unique role played by many anti biotics in the development of our understanding of nucleic acid synthesis and function and its relationship to protein synthesis and cell physiology has led rapidly to a very precise, understanding of how many of these same antibiotics inhibit susceptible cells.


Book Synopsis Mechanism of Action of Antimicrobial and Antitumor Agents by : J. F. Snell

Download or read book Mechanism of Action of Antimicrobial and Antitumor Agents written by J. F. Snell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the third in the series devoted to Antibiotics initiated by Springer Verlag in 1967. The first two volumes were devoted to the Mode of Action of Antibiotics and Biogenesis, respectively and were received graciously. During the intervening years these two works have been used often by research workers and students alike and have been quoted extensively. Although a number of other excellent treatises on antibiotics have appeared, the Springer series has set a standard for thoroughness and quality that meets the need of the scientific community. It is against this background that the present Editors set about the preparation of a third volume in the Series on Antibiotics. Since the appearance of Volume I, also dealing with Mechanism of Action, tremendous strides have been made in the depth and breadth of our knowledge of molecular biology, microbial chemistry and molecular pharmacology and of their direct application to studies on the mode of action of drugs. The field of molecular biology itself was in its relative infancy during the preceding decade and the unique role played by many anti biotics in the development of our understanding of nucleic acid synthesis and function and its relationship to protein synthesis and cell physiology has led rapidly to a very precise, understanding of how many of these same antibiotics inhibit susceptible cells.


Antibiotics

Antibiotics

Author:

Publisher:

Published: 1967

Total Pages:

ISBN-13: 9780387121697

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Book Synopsis Antibiotics by :

Download or read book Antibiotics written by and published by . This book was released on 1967 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:


Antibiotics

Antibiotics

Author:

Publisher:

Published: 1967

Total Pages:

ISBN-13:

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Book Synopsis Antibiotics by :

Download or read book Antibiotics written by and published by . This book was released on 1967 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:


Mechanisms of Action of Antimicrobial Agents and Antitumor Agents

Mechanisms of Action of Antimicrobial Agents and Antitumor Agents

Author: John William Corcoran

Publisher:

Published: 1975

Total Pages: 742

ISBN-13:

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Book Synopsis Mechanisms of Action of Antimicrobial Agents and Antitumor Agents by : John William Corcoran

Download or read book Mechanisms of Action of Antimicrobial Agents and Antitumor Agents written by John William Corcoran and published by . This book was released on 1975 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Mechanism of Action

Mechanism of Action

Author: David Gottlieb

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 797

ISBN-13: 3642460518

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The idea for publishing these books on the mechanism of action and on the biosynthesis of antibiotics was born of frustration in our attempts to keep abreast of the literature. Gone were the years when we were able to keep a biblio graphy on antibiotics and feel confident that we could find everything that was being published on this subject. These fields of investigation were moving for ward so rapidly and were encompassing so wide a range of specialized areas in microbiology and chemistry that it was almost impossible to keep abreast of developments. In our naivete and enthusiasm, however, we were unaware that we were toying with an idea that might enmesh us, that we were creating an entity with a life of its own, that we were letting loose a Golom who instead of being our servant would be our master. That we set up ideals for these books is obvious; they would be current guides to developments and information in the areas of mechanism of action and bio synthesis of antibiotics. For almost every subject, we wished to enlist the aid of an investigator who himself had played a part in determining the nature of the phenomena that were being discussed. One concept for the books was that they include only antibiotics for which a definitive, well-documented mechanism of action or biosynthetic pathway was known.


Book Synopsis Mechanism of Action by : David Gottlieb

Download or read book Mechanism of Action written by David Gottlieb and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 797 pages. Available in PDF, EPUB and Kindle. Book excerpt: The idea for publishing these books on the mechanism of action and on the biosynthesis of antibiotics was born of frustration in our attempts to keep abreast of the literature. Gone were the years when we were able to keep a biblio graphy on antibiotics and feel confident that we could find everything that was being published on this subject. These fields of investigation were moving for ward so rapidly and were encompassing so wide a range of specialized areas in microbiology and chemistry that it was almost impossible to keep abreast of developments. In our naivete and enthusiasm, however, we were unaware that we were toying with an idea that might enmesh us, that we were creating an entity with a life of its own, that we were letting loose a Golom who instead of being our servant would be our master. That we set up ideals for these books is obvious; they would be current guides to developments and information in the areas of mechanism of action and bio synthesis of antibiotics. For almost every subject, we wished to enlist the aid of an investigator who himself had played a part in determining the nature of the phenomena that were being discussed. One concept for the books was that they include only antibiotics for which a definitive, well-documented mechanism of action or biosynthetic pathway was known.


Antibiotics

Antibiotics

Author: John W. Corcoran

Publisher:

Published: 1975

Total Pages: 742

ISBN-13:

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Book Synopsis Antibiotics by : John W. Corcoran

Download or read book Antibiotics written by John W. Corcoran and published by . This book was released on 1975 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Antibacterial Agents

Antibacterial Agents

Author: Rosaleen Anderson

Publisher: John Wiley & Sons

Published: 2012-05-30

Total Pages: 379

ISBN-13: 1118325443

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Antibacterial agents act against bacterial infection either by killing the bacterium or by arresting its growth. They do this by targeting bacterial DNA and its associated processes, attacking bacterial metabolic processes including protein synthesis, or interfering with bacterial cell wall synthesis and function. Antibacterial Agents is an essential guide to this important class of chemotherapeutic drugs. Compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. The book uses an integrated “lab-to-clinic” approach which covers drug discovery, source or synthesis, mode of action, mechanisms of resistance, clinical aspects (including links to current guidelines, significant drug interactions, cautions and contraindications), prodrugs and future improvements. Agents covered include: agents targeting DNA - quinolone, rifamycin, and nitroimidazole antibacterial agents agents targeting metabolic processes - sulfonamide antibacterial agents and trimethoprim agents targeting protein synthesis - aminoglycoside, macrolide and tetracycline antibiotics, chloramphenicol, and oxazolidinones agents targeting cell wall synthesis - β-Lactam and glycopeptide antibiotics, cycloserine, isonaizid, and daptomycin Antibacterial Agents will find a place on the bookshelves of students of pharmacy, pharmacology, pharmaceutical sciences, drug design/discovery, and medicinal chemistry, and as a bench reference for pharmacists and pharmaceutical researchers in academia and industry.


Book Synopsis Antibacterial Agents by : Rosaleen Anderson

Download or read book Antibacterial Agents written by Rosaleen Anderson and published by John Wiley & Sons. This book was released on 2012-05-30 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibacterial agents act against bacterial infection either by killing the bacterium or by arresting its growth. They do this by targeting bacterial DNA and its associated processes, attacking bacterial metabolic processes including protein synthesis, or interfering with bacterial cell wall synthesis and function. Antibacterial Agents is an essential guide to this important class of chemotherapeutic drugs. Compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. The book uses an integrated “lab-to-clinic” approach which covers drug discovery, source or synthesis, mode of action, mechanisms of resistance, clinical aspects (including links to current guidelines, significant drug interactions, cautions and contraindications), prodrugs and future improvements. Agents covered include: agents targeting DNA - quinolone, rifamycin, and nitroimidazole antibacterial agents agents targeting metabolic processes - sulfonamide antibacterial agents and trimethoprim agents targeting protein synthesis - aminoglycoside, macrolide and tetracycline antibiotics, chloramphenicol, and oxazolidinones agents targeting cell wall synthesis - β-Lactam and glycopeptide antibiotics, cycloserine, isonaizid, and daptomycin Antibacterial Agents will find a place on the bookshelves of students of pharmacy, pharmacology, pharmaceutical sciences, drug design/discovery, and medicinal chemistry, and as a bench reference for pharmacists and pharmaceutical researchers in academia and industry.


Antibiotics

Antibiotics

Author: David Gottlieb

Publisher: Springer

Published: 2013-11-27

Total Pages: 797

ISBN-13: 3662384396

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Book Synopsis Antibiotics by : David Gottlieb

Download or read book Antibiotics written by David Gottlieb and published by Springer. This book was released on 2013-11-27 with total page 797 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Antibiotics. 6V. V1- Mechanism of Action. Ed by David Gottlieb and Paul D Shaw. 1967. V2- Biosynthesis. V3- Mechanism of Action of Antimicrobial and Antitumor Agents. V4- Biosynthesis. V5.Pt1- Mechanism of Action of Antibacterial Agents. V5.Pt2- Mechanism of Action of Antieukaryotic and Antiviral Compounds. V6- Models and Mechanisms of Microbial Growth Inhibitors

Antibiotics. 6V. V1- Mechanism of Action. Ed by David Gottlieb and Paul D Shaw. 1967. V2- Biosynthesis. V3- Mechanism of Action of Antimicrobial and Antitumor Agents. V4- Biosynthesis. V5.Pt1- Mechanism of Action of Antibacterial Agents. V5.Pt2- Mechanism of Action of Antieukaryotic and Antiviral Compounds. V6- Models and Mechanisms of Microbial Growth Inhibitors

Author: David Gottlieb (ed)

Publisher:

Published: 1979

Total Pages:

ISBN-13:

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Book Synopsis Antibiotics. 6V. V1- Mechanism of Action. Ed by David Gottlieb and Paul D Shaw. 1967. V2- Biosynthesis. V3- Mechanism of Action of Antimicrobial and Antitumor Agents. V4- Biosynthesis. V5.Pt1- Mechanism of Action of Antibacterial Agents. V5.Pt2- Mechanism of Action of Antieukaryotic and Antiviral Compounds. V6- Models and Mechanisms of Microbial Growth Inhibitors by : David Gottlieb (ed)

Download or read book Antibiotics. 6V. V1- Mechanism of Action. Ed by David Gottlieb and Paul D Shaw. 1967. V2- Biosynthesis. V3- Mechanism of Action of Antimicrobial and Antitumor Agents. V4- Biosynthesis. V5.Pt1- Mechanism of Action of Antibacterial Agents. V5.Pt2- Mechanism of Action of Antieukaryotic and Antiviral Compounds. V6- Models and Mechanisms of Microbial Growth Inhibitors written by David Gottlieb (ed) and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:


Mechanism of Action of Antieukaryotic and Antiviral Compounds

Mechanism of Action of Antieukaryotic and Antiviral Compounds

Author: Fred E. Hahn

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 484

ISBN-13: 3642464076

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When Antibiotics I was published in 1967, the teleological view was held by some that" antibiotics" were substances elaborated by certain microorgan isms for the purpose of competing with other microorganisms for survival in mixed ecological environments. However, not only had J. EHRLICH and his associates shown 15 years earlier that chloramphenicol was produced by Strepto myces venezuelae in cultures of sterilized soils but not in parallel cultures of the same soils which were not sterilized, but operationally, the search for anti cancer antibiotics was actively under way (Antibiotics I reporting on numerous such substances), although the concept of antibiosis could not logically justify such undertakings. This editor hesitates to accept the use of the term "antibiotic" for anti microbial agents of non microbiological origins which is sometimes encountered, but neither does he subscribe to the view that antibiotics are in some fundamental manner different from chemotherapeutic substances of other origins. Modes and mechanisms of action of chemotherapeutic compounds are not systematic functions of their origins nor of the taxonomical position of the target organisms. Consequently, in the selection of topics for Antibiotics III (published in 1975), synthetic drugs and natural products of higher plants (alkaloids) were represented, along with antibiotics in the strict sense of the definition. We now present Antibiotics V, for whose assembly the same selection criteria were applied as for Antibiotics Ill. The aggregate length of the contributions rendered it impractical to place the entire text between the covers of one book.


Book Synopsis Mechanism of Action of Antieukaryotic and Antiviral Compounds by : Fred E. Hahn

Download or read book Mechanism of Action of Antieukaryotic and Antiviral Compounds written by Fred E. Hahn and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: When Antibiotics I was published in 1967, the teleological view was held by some that" antibiotics" were substances elaborated by certain microorgan isms for the purpose of competing with other microorganisms for survival in mixed ecological environments. However, not only had J. EHRLICH and his associates shown 15 years earlier that chloramphenicol was produced by Strepto myces venezuelae in cultures of sterilized soils but not in parallel cultures of the same soils which were not sterilized, but operationally, the search for anti cancer antibiotics was actively under way (Antibiotics I reporting on numerous such substances), although the concept of antibiosis could not logically justify such undertakings. This editor hesitates to accept the use of the term "antibiotic" for anti microbial agents of non microbiological origins which is sometimes encountered, but neither does he subscribe to the view that antibiotics are in some fundamental manner different from chemotherapeutic substances of other origins. Modes and mechanisms of action of chemotherapeutic compounds are not systematic functions of their origins nor of the taxonomical position of the target organisms. Consequently, in the selection of topics for Antibiotics III (published in 1975), synthetic drugs and natural products of higher plants (alkaloids) were represented, along with antibiotics in the strict sense of the definition. We now present Antibiotics V, for whose assembly the same selection criteria were applied as for Antibiotics Ill. The aggregate length of the contributions rendered it impractical to place the entire text between the covers of one book.