Download Microbial Adhesion And Aggregation full books in PDF, epub, and Kindle. Read online Microbial Adhesion And Aggregation ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Microbial Adhesion and Aggregation by : K.C. Marshall
Download or read book Microbial Adhesion and Aggregation written by K.C. Marshall and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Microbial Adhesion and Aggregation by :
Download or read book Microbial Adhesion and Aggregation written by and published by . This book was released on with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis MICROBIAL ADHESION AND AGGREGATION. by :
Download or read book MICROBIAL ADHESION AND AGGREGATION. written by and published by . This book was released on 1984 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Microbial Adhesion and Aggregation by : K.C. Marshall
Download or read book Microbial Adhesion and Aggregation written by K.C. Marshall and published by Springer. This book was released on 1984-12-01 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Microbial Adhesion and Aggregation by :
Download or read book Microbial Adhesion and Aggregation written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
... an important milestone in the field of microbial adhesion and should be indispensable to all workers in that discipline Journal of Dispersion Science and Technology.
Book Synopsis Microbial Cell Surface Hydrophobicity by : R. J. Doyle
Download or read book Microbial Cell Surface Hydrophobicity written by R. J. Doyle and published by ASM Press. This book was released on 1990 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: ... an important milestone in the field of microbial adhesion and should be indispensable to all workers in that discipline Journal of Dispersion Science and Technology.
This text covers in detail bacteria and yeasts, including an overall perspective of microbial aggregation as fundamental form and function, which is presented here to include systems still to be treated in detail.
Book Synopsis Microbial Aggregation by : Calleja
Download or read book Microbial Aggregation written by Calleja and published by CRC Press. This book was released on 2018-05-04 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text covers in detail bacteria and yeasts, including an overall perspective of microbial aggregation as fundamental form and function, which is presented here to include systems still to be treated in detail.
Book Synopsis Microbial Adhesion to Surfaces by : R. C. W. Berkeley
Download or read book Microbial Adhesion to Surfaces written by R. C. W. Berkeley and published by . This book was released on 1980 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Antibiotic-resistant bacterial infections are a serious and immediate threat to global public health. In the United States alone, over 2 million individuals develop antibiotic-resistant infections annually, resulting in 23,000 deaths and $20 billion in excess health care costs. Virulence factors that allow bacteria to invade and persist within the host are promising targets for novel antimicrobial agents that could be used to curb the spread of antibiotic resistance. Development of therapeutics that can selectively eliminate pathogenic bacteria while sparing the beneficial host microbiota requires a detailed molecular understanding of critical virulence factors that facilitate interactions between pathogens and their environments. Two such factors are Chaperone-Usher Pathway (CUP) pili, which mediate bacterial adhesion, and curli, which constitute the major extracellular matrix component of many biofilms. In this dissertation, I have elucidated the structure of two pilus adhesins thought to mediate colonization of the gastrointestinal tract and determined the mechanism of CsgE assembly factor function in curli biogenesis. CUP pili comprise hundreds of repeating structural subunits capped by an adhesin whose N-terminal lectin domain binds host receptors with stereochemical specificity, thus facilitating the colonization of specific host niches by Gram-negative bacteria. Using X-ray crystallography, I determined that the UclD adhesin on the F17-like pilus contains a transverse binding groove that binds O-glycans in the colonic crypts. Conversely, I found that the YehD adhesin contains a unique helix-loop-helix motif that can pivot open to reveal a deep hydrophobic pocket. Additional structural and genetic studies of the Yeh pilus rod reveal a tightly-wound right-handed helix that has maintained its biomechanical response to external force through purifying evolutionary selection. I have also utilized X-ray crystallography to elucidate the structure-activity relationship of high-affinity compounds that inhibit the binding of two additional pilus adhesins, FimH and FmlH, to the urinary tract during acute and chronic urinary tract infection. Finally, I have performed genetic and biochemical studies to elucidate the role of CsgE in bacterial biofilm formation. During curli biogenesis, I found that CsgE uses a series of specific and nonspecific electrostatic interactions to bind the major amyloid subunit CsgA and deliver it to the CsgG outer membrane pore, thus preventing premature aggregation and cellular toxicity. In aggregate, these findings have advanced our molecular understanding of bacterial adhesion during pathogenesis and illuminated novel pathways for the treatment of antibiotic-resistant infections.
Book Synopsis Molecular Insights Into Microbial Adhesion by : Roger Davies Klein
Download or read book Molecular Insights Into Microbial Adhesion written by Roger Davies Klein and published by . This book was released on 2020 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotic-resistant bacterial infections are a serious and immediate threat to global public health. In the United States alone, over 2 million individuals develop antibiotic-resistant infections annually, resulting in 23,000 deaths and $20 billion in excess health care costs. Virulence factors that allow bacteria to invade and persist within the host are promising targets for novel antimicrobial agents that could be used to curb the spread of antibiotic resistance. Development of therapeutics that can selectively eliminate pathogenic bacteria while sparing the beneficial host microbiota requires a detailed molecular understanding of critical virulence factors that facilitate interactions between pathogens and their environments. Two such factors are Chaperone-Usher Pathway (CUP) pili, which mediate bacterial adhesion, and curli, which constitute the major extracellular matrix component of many biofilms. In this dissertation, I have elucidated the structure of two pilus adhesins thought to mediate colonization of the gastrointestinal tract and determined the mechanism of CsgE assembly factor function in curli biogenesis. CUP pili comprise hundreds of repeating structural subunits capped by an adhesin whose N-terminal lectin domain binds host receptors with stereochemical specificity, thus facilitating the colonization of specific host niches by Gram-negative bacteria. Using X-ray crystallography, I determined that the UclD adhesin on the F17-like pilus contains a transverse binding groove that binds O-glycans in the colonic crypts. Conversely, I found that the YehD adhesin contains a unique helix-loop-helix motif that can pivot open to reveal a deep hydrophobic pocket. Additional structural and genetic studies of the Yeh pilus rod reveal a tightly-wound right-handed helix that has maintained its biomechanical response to external force through purifying evolutionary selection. I have also utilized X-ray crystallography to elucidate the structure-activity relationship of high-affinity compounds that inhibit the binding of two additional pilus adhesins, FimH and FmlH, to the urinary tract during acute and chronic urinary tract infection. Finally, I have performed genetic and biochemical studies to elucidate the role of CsgE in bacterial biofilm formation. During curli biogenesis, I found that CsgE uses a series of specific and nonspecific electrostatic interactions to bind the major amyloid subunit CsgA and deliver it to the CsgG outer membrane pore, thus preventing premature aggregation and cellular toxicity. In aggregate, these findings have advanced our molecular understanding of bacterial adhesion during pathogenesis and illuminated novel pathways for the treatment of antibiotic-resistant infections.
Book Synopsis Bacterial Adhesion, Aggregation and Flocculation Mechanisms in Activated Sludge by : Anna Zita
Download or read book Bacterial Adhesion, Aggregation and Flocculation Mechanisms in Activated Sludge written by Anna Zita and published by . This book was released on 1997 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt: