Microbial Toxins

Microbial Toxins

Author: P. Gopalakrishnakone

Publisher: Springer

Published: 2018-03-14

Total Pages: 502

ISBN-13: 9789400764484

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In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.


Book Synopsis Microbial Toxins by : P. Gopalakrishnakone

Download or read book Microbial Toxins written by P. Gopalakrishnakone and published by Springer. This book was released on 2018-03-14 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.

Microbial Toxins

Microbial Toxins

Author: Thomas Proft

Publisher: Caister Academic Press Limited

Published: 2009

Total Pages: 0

ISBN-13: 9781904455448

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Toxins are important virulence determinants responsible for microbial pathogenicity and/or evasion of the host immune response. Understanding the molecular and cellular biology of toxins is critical for the development of new anti-toxin strategies, particularly for those with bioterrorism capability. Indeed, potential applications of toxin research extend beyond simply combating microbial virulence and include the development of novel anti-cancer drugs and other frontline medicines, use of toxins as tools in neurobiology and cellular biology, etc. This timely volume serves as an update on important recent advances. Written by internationally respected scientists, topics reviewed include: toxins carried by mobile genetic elements, botulinum neurotoxins, anthrax, subtilase cytotoxin, Pasteurella multocida toxin, RTX toxins of vibrios, vacA toxin, staphylococcal immune evasion toxins, and fungal ribotoxins. The book is essential reading for everyone with an interest in microbial toxins, and it is recommended for other scientists with an interest in microbiology, bioterrorism, microbial pathogenesis, and microbial genomics.


Book Synopsis Microbial Toxins by : Thomas Proft

Download or read book Microbial Toxins written by Thomas Proft and published by Caister Academic Press Limited. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxins are important virulence determinants responsible for microbial pathogenicity and/or evasion of the host immune response. Understanding the molecular and cellular biology of toxins is critical for the development of new anti-toxin strategies, particularly for those with bioterrorism capability. Indeed, potential applications of toxin research extend beyond simply combating microbial virulence and include the development of novel anti-cancer drugs and other frontline medicines, use of toxins as tools in neurobiology and cellular biology, etc. This timely volume serves as an update on important recent advances. Written by internationally respected scientists, topics reviewed include: toxins carried by mobile genetic elements, botulinum neurotoxins, anthrax, subtilase cytotoxin, Pasteurella multocida toxin, RTX toxins of vibrios, vacA toxin, staphylococcal immune evasion toxins, and fungal ribotoxins. The book is essential reading for everyone with an interest in microbial toxins, and it is recommended for other scientists with an interest in microbiology, bioterrorism, microbial pathogenesis, and microbial genomics.

Microbial Toxins in Foods and Feeds

Microbial Toxins in Foods and Feeds

Author: V.R. Jr. Dowell

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 598

ISBN-13: 1461306639

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The October/November 1988 symposium was jointly sponsored by the US and Japanese Panels on Toxic Microorganisms of the United States-Japan Cooperative Program on Development and Utilization of Natural Resources. This proceedings volume considers, in three sections, the cellular and molecular aspects


Book Synopsis Microbial Toxins in Foods and Feeds by : V.R. Jr. Dowell

Download or read book Microbial Toxins in Foods and Feeds written by V.R. Jr. Dowell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: The October/November 1988 symposium was jointly sponsored by the US and Japanese Panels on Toxic Microorganisms of the United States-Japan Cooperative Program on Development and Utilization of Natural Resources. This proceedings volume considers, in three sections, the cellular and molecular aspects

Damp Indoor Spaces and Health

Damp Indoor Spaces and Health

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2004-10-01

Total Pages: 369

ISBN-13: 0309091934

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Almost all homes, apartments, and commercial buildings will experience leaks, flooding, or other forms of excessive indoor dampness at some point. Not only is excessive dampness a health problem by itself, it also contributes to several other potentially problematic types of situations. Molds and other microbial agents favor damp indoor environments, and excess moisture may initiate the release of chemical emissions from damaged building materials and furnishings. This new book from the Institute of Medicine examines the health impact of exposures resulting from damp indoor environments and offers recommendations for public health interventions. Damp Indoor Spaces and Health covers a broad range of topics. The book not only examines the relationship between damp or moldy indoor environments and adverse health outcomes but also discusses how and where buildings get wet, how dampness influences microbial growth and chemical emissions, ways to prevent and remediate dampness, and elements of a public health response to the issues. A comprehensive literature review finds sufficient evidence of an association between damp indoor environments and some upper respiratory tract symptoms, coughing, wheezing, and asthma symptoms in sensitized persons. This important book will be of interest to a wide-ranging audience of science, health, engineering, and building professionals, government officials, and members of the public.


Book Synopsis Damp Indoor Spaces and Health by : Institute of Medicine

Download or read book Damp Indoor Spaces and Health written by Institute of Medicine and published by National Academies Press. This book was released on 2004-10-01 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Almost all homes, apartments, and commercial buildings will experience leaks, flooding, or other forms of excessive indoor dampness at some point. Not only is excessive dampness a health problem by itself, it also contributes to several other potentially problematic types of situations. Molds and other microbial agents favor damp indoor environments, and excess moisture may initiate the release of chemical emissions from damaged building materials and furnishings. This new book from the Institute of Medicine examines the health impact of exposures resulting from damp indoor environments and offers recommendations for public health interventions. Damp Indoor Spaces and Health covers a broad range of topics. The book not only examines the relationship between damp or moldy indoor environments and adverse health outcomes but also discusses how and where buildings get wet, how dampness influences microbial growth and chemical emissions, ways to prevent and remediate dampness, and elements of a public health response to the issues. A comprehensive literature review finds sufficient evidence of an association between damp indoor environments and some upper respiratory tract symptoms, coughing, wheezing, and asthma symptoms in sensitized persons. This important book will be of interest to a wide-ranging audience of science, health, engineering, and building professionals, government officials, and members of the public.

Bacterial Toxins

Bacterial Toxins

Author: Otto Holst

Publisher: Springer Science & Business Media

Published: 2008-02-05

Total Pages: 378

ISBN-13: 1592590527

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The interest of investigators across a broad spectrum of scientific dis- plines has been steadily stimulated by the field of bacterial toxin research, an area that makes use of a large variety of biological, chemical, physicochemical, and medically oriented approaches. Researchers studying bacterial toxins need to be acquainted with all these disciplines in order to work effectively in the field. To date, there has been no published collection offering detailed descr- tions of the techniques and methods needed by researchers operating across the field’sdiverse areas. The present volume Bacterial Toxins: Methods and Pro- cols, is intended to fill this gap. Bacterial Toxins: Methods and Protocols consists of two sections: one on protein toxins (15 chapters) and one on endotoxins (5 chapters). Each s- tion is introduced by an overview article (Chapters 1 and 16). The protocols collected represent state-of-the-art techniques that each have high impact on future bacterial toxin research. All methods are described by authors who have regularly been using the protocol in their own laboratories. Included in each chapter is a brief introduction to the method being described.


Book Synopsis Bacterial Toxins by : Otto Holst

Download or read book Bacterial Toxins written by Otto Holst and published by Springer Science & Business Media. This book was released on 2008-02-05 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interest of investigators across a broad spectrum of scientific dis- plines has been steadily stimulated by the field of bacterial toxin research, an area that makes use of a large variety of biological, chemical, physicochemical, and medically oriented approaches. Researchers studying bacterial toxins need to be acquainted with all these disciplines in order to work effectively in the field. To date, there has been no published collection offering detailed descr- tions of the techniques and methods needed by researchers operating across the field’sdiverse areas. The present volume Bacterial Toxins: Methods and Pro- cols, is intended to fill this gap. Bacterial Toxins: Methods and Protocols consists of two sections: one on protein toxins (15 chapters) and one on endotoxins (5 chapters). Each s- tion is introduced by an overview article (Chapters 1 and 16). The protocols collected represent state-of-the-art techniques that each have high impact on future bacterial toxin research. All methods are described by authors who have regularly been using the protocol in their own laboratories. Included in each chapter is a brief introduction to the method being described.

Microbial Toxins

Microbial Toxins

Author: National Institute of General Medical Sciences (U.S.). Microbiology Training Committee

Publisher:

Published: 1971

Total Pages: 36

ISBN-13:

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Book Synopsis Microbial Toxins by : National Institute of General Medical Sciences (U.S.). Microbiology Training Committee

Download or read book Microbial Toxins written by National Institute of General Medical Sciences (U.S.). Microbiology Training Committee and published by . This book was released on 1971 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bacterial Toxins

Bacterial Toxins

Author: Klaus Aktories

Publisher: John Wiley & Sons

Published: 2008-09-26

Total Pages: 334

ISBN-13: 3527614605

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This is a survey of well characterized and recently discovered bacterial protein toxins. Leading investigators of the respective toxins review the various molecular mechanisms of action, ranging from toxin-induced ADP-ribosylation up to membrane perforation by pore-forming toxins. Thy also describe the consequences on host physiology before focusing on potential applications as cell biological and pharmacological tools for research and medical applications. Detailed descriptions of the methodology include the engineering and use of modified and chimeric toxins for better performance. A solid introduction to toxin structure and functions, as well as a valuable source of methodology for researchers in molecular biology, pharmacology and experimental medicine.


Book Synopsis Bacterial Toxins by : Klaus Aktories

Download or read book Bacterial Toxins written by Klaus Aktories and published by John Wiley & Sons. This book was released on 2008-09-26 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a survey of well characterized and recently discovered bacterial protein toxins. Leading investigators of the respective toxins review the various molecular mechanisms of action, ranging from toxin-induced ADP-ribosylation up to membrane perforation by pore-forming toxins. Thy also describe the consequences on host physiology before focusing on potential applications as cell biological and pharmacological tools for research and medical applications. Detailed descriptions of the methodology include the engineering and use of modified and chimeric toxins for better performance. A solid introduction to toxin structure and functions, as well as a valuable source of methodology for researchers in molecular biology, pharmacology and experimental medicine.

Microbial Toxins

Microbial Toxins

Author: P. Gopalakrishnakone

Publisher:

Published:

Total Pages:

ISBN-13: 9789400767256

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Book Synopsis Microbial Toxins by : P. Gopalakrishnakone

Download or read book Microbial Toxins written by P. Gopalakrishnakone and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Microbial Toxin Research and Its Biotechnological Exploitation

Advances in Microbial Toxin Research and Its Biotechnological Exploitation

Author: Rajeev K. Upadhyay

Publisher: Springer Science & Business Media

Published: 2013-03-14

Total Pages: 290

ISBN-13: 1475744390

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Microbial toxins are secondary metabolites that accumulate in the organism and, to a large extent, are metabolically inactive towards the organism that produces them. The discovery of penicillin, a secondary metabolite of Penicillium notatum West (= P. chrysogenum Thom), in 1929 marked a milestone in the development of antibiotics (microbial toxins). In the intensive studies that followed this discovery, scientists chemically characterized several new molecules (toxins) from secondary metabolites of microbes, some having a definite function in causing pathogenesis in plants. Toxins are also known to playa significant role in inciting animal (human) and insect diseases and as plant growth regulators. Many common toxins have also been isolated from different microbes exhibiting a wide spectrum of biological activity. Toxins are broadly divisible into several characteristic groupings - polyketides, oxygen heterocyclic compounds, pyrons, terpenoidS, amino acids - diketopiperazines, polypeptides etc. Recent research has indicated that these toxins play an important role in plant pathogenesis, disease epidemics, plant breeding, biological control of plant pathogens and insect pests, induced resistance, plant-pathogen interactions etc. Toxins produced by weed pathogens are exploited as lead molecules in developing environmentally friendly herbicides.


Book Synopsis Advances in Microbial Toxin Research and Its Biotechnological Exploitation by : Rajeev K. Upadhyay

Download or read book Advances in Microbial Toxin Research and Its Biotechnological Exploitation written by Rajeev K. Upadhyay and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial toxins are secondary metabolites that accumulate in the organism and, to a large extent, are metabolically inactive towards the organism that produces them. The discovery of penicillin, a secondary metabolite of Penicillium notatum West (= P. chrysogenum Thom), in 1929 marked a milestone in the development of antibiotics (microbial toxins). In the intensive studies that followed this discovery, scientists chemically characterized several new molecules (toxins) from secondary metabolites of microbes, some having a definite function in causing pathogenesis in plants. Toxins are also known to playa significant role in inciting animal (human) and insect diseases and as plant growth regulators. Many common toxins have also been isolated from different microbes exhibiting a wide spectrum of biological activity. Toxins are broadly divisible into several characteristic groupings - polyketides, oxygen heterocyclic compounds, pyrons, terpenoidS, amino acids - diketopiperazines, polypeptides etc. Recent research has indicated that these toxins play an important role in plant pathogenesis, disease epidemics, plant breeding, biological control of plant pathogens and insect pests, induced resistance, plant-pathogen interactions etc. Toxins produced by weed pathogens are exploited as lead molecules in developing environmentally friendly herbicides.

Microbial Toxins and Related Contamination in the Food Industry

Microbial Toxins and Related Contamination in the Food Industry

Author: Gabriella Caruso

Publisher: Springer

Published: 2015-06-29

Total Pages: 106

ISBN-13: 3319205595

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This Brief concerns the chemical risk in food products from the viewpoint of microbiology. The “Hazard Analysis and Critical Control Point” (HACCP) approach, which is applied for this purpose, is dedicated to the study and the analysis of all possible dangers by food consumptions and the related countermeasures with the aim of protecting the health of consumers. This difficult objective is highly multidisciplinary and requires a plethora of different competencies. This book thus addresses chemists, microbiologists, food technologists, medical professionals and veterinarians. The chemical risks described in this book are related to food additives, contaminants by food packaging materials, chemicals from cleaning systems and microbial toxins. The present book gives an introduction and overview of these various topics.


Book Synopsis Microbial Toxins and Related Contamination in the Food Industry by : Gabriella Caruso

Download or read book Microbial Toxins and Related Contamination in the Food Industry written by Gabriella Caruso and published by Springer. This book was released on 2015-06-29 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Brief concerns the chemical risk in food products from the viewpoint of microbiology. The “Hazard Analysis and Critical Control Point” (HACCP) approach, which is applied for this purpose, is dedicated to the study and the analysis of all possible dangers by food consumptions and the related countermeasures with the aim of protecting the health of consumers. This difficult objective is highly multidisciplinary and requires a plethora of different competencies. This book thus addresses chemists, microbiologists, food technologists, medical professionals and veterinarians. The chemical risks described in this book are related to food additives, contaminants by food packaging materials, chemicals from cleaning systems and microbial toxins. The present book gives an introduction and overview of these various topics.