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Author: Chin-Yang Li
Publisher: Igaku-Shoin Medical Publishers
Published: 1996
Total Pages: 280
ISBN-13:
DOWNLOAD EBOOKDownload or read book Modern Modalities for the Diagnosis of Hematologic Neoplasms written by Chin-Yang Li and published by Igaku-Shoin Medical Publishers. This book was released on 1996 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author: Lubomir Sokol
Publisher: Springer
Published: 2024-11-09
Total Pages: 0
ISBN-13: 9783031623721
DOWNLOAD EBOOKIn the current digital era with the exponential growth of medical knowledge, voluminous textbooks have gradually been replaced by the pocketbooks with tables, figures, images, and e-links to digital book versions with supplemental materials available online. The advent of novel next-generation sequencing (NGS) and multi-omics single cell methods have uncovered causative molecular mechanisms in most of the known non-neoplastic hematologic disorders. There is an urgent need for a concise and up-to-date handbook focused on non-malignant hematology. The book describes characteristic clinical features and state-of-the-art diagnostic approaches of non-neoplastic hematologic disorders. It introduces modern molecular biomarkers with enormous diagnostic and prognostic value and novel targeted gene therapy. Differential diagnosis also includes relevant hematologic malignancies that could represent diagnostic pitfalls. Chapters include take home points for each disorder in concise and easy memorable manner. The book also provides diagnostic algorithms, novel prognostic and predictive factors, up-to-date treatment options, clinically relevant molecular signatures, and ongoing promising clinical trials if available. There are more than 100 questions and answers with comments on laboratory values, updated cytogenetic and mutational profiles. Non-Neoplastic Hematologic Disorders: A Quick Review of Modern Diagnostic and Therapeutic Approaches provides concise clinical and laboratory information about most common non-neoplastic hematologic disorder for practicing hematologists, oncologists, hematopathologists, molecular pathologists, internal medicine specialists, pediatricians, research nurses, nurse practitioners, and trainees at all levels.
Download or read book Non-Neoplastic Hematologic Disorders written by Lubomir Sokol and published by Springer. This book was released on 2024-11-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the current digital era with the exponential growth of medical knowledge, voluminous textbooks have gradually been replaced by the pocketbooks with tables, figures, images, and e-links to digital book versions with supplemental materials available online. The advent of novel next-generation sequencing (NGS) and multi-omics single cell methods have uncovered causative molecular mechanisms in most of the known non-neoplastic hematologic disorders. There is an urgent need for a concise and up-to-date handbook focused on non-malignant hematology. The book describes characteristic clinical features and state-of-the-art diagnostic approaches of non-neoplastic hematologic disorders. It introduces modern molecular biomarkers with enormous diagnostic and prognostic value and novel targeted gene therapy. Differential diagnosis also includes relevant hematologic malignancies that could represent diagnostic pitfalls. Chapters include take home points for each disorder in concise and easy memorable manner. The book also provides diagnostic algorithms, novel prognostic and predictive factors, up-to-date treatment options, clinically relevant molecular signatures, and ongoing promising clinical trials if available. There are more than 100 questions and answers with comments on laboratory values, updated cytogenetic and mutational profiles. Non-Neoplastic Hematologic Disorders: A Quick Review of Modern Diagnostic and Therapeutic Approaches provides concise clinical and laboratory information about most common non-neoplastic hematologic disorder for practicing hematologists, oncologists, hematopathologists, molecular pathologists, internal medicine specialists, pediatricians, research nurses, nurse practitioners, and trainees at all levels.
Author: Michal Witt
Publisher: Springer Science & Business Media
Published: 2012-06-30
Total Pages: 468
ISBN-13: 3642294677
DOWNLOAD EBOOKThis book provides a state-of-the-art approach to the molecular basis of hematologic diseases and its translation into improved diagnostics and novel therapeutic strategies. Several representative hemato-oncologic malignancies are analyzed in detail: acute lymphoblastic leukemia, acute myeloid leukemia, B-cell Non-Hodgkin lymphomas, multiple myeloma, chronic lymphocytic leukemia, chronic myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms. Experts in the field describe the molecular methods applied for modern diagnostics and therapies, such as hematopoietic stem cell transplantation, donor recipient matching, banking of biological material, analyses of post-transplant chimerism, and minimal residual disease monitoring. The volume concludes with an extensive section comprising thorough step-by-step protocols of molecular techniques in hematology, all of them validated in the authors’ own laboratories.
Download or read book Molecular Aspects of Hematologic Malignancies written by Michal Witt and published by Springer Science & Business Media. This book was released on 2012-06-30 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a state-of-the-art approach to the molecular basis of hematologic diseases and its translation into improved diagnostics and novel therapeutic strategies. Several representative hemato-oncologic malignancies are analyzed in detail: acute lymphoblastic leukemia, acute myeloid leukemia, B-cell Non-Hodgkin lymphomas, multiple myeloma, chronic lymphocytic leukemia, chronic myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms. Experts in the field describe the molecular methods applied for modern diagnostics and therapies, such as hematopoietic stem cell transplantation, donor recipient matching, banking of biological material, analyses of post-transplant chimerism, and minimal residual disease monitoring. The volume concludes with an extensive section comprising thorough step-by-step protocols of molecular techniques in hematology, all of them validated in the authors’ own laboratories.
Author: National Academies of Sciences Engineering and Medicine
Publisher:
Published: 2021-09-09
Total Pages:
ISBN-13: 9780309683494
DOWNLOAD EBOOKSince the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.
Download or read book Childhood Cancer and Functional Impacts Across the Care Continuum written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2021-09-09 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.
Author: Tsieh Sun
Publisher: Lippincott Williams & Wilkins
Published: 2008
Total Pages: 362
ISBN-13: 9780781784009
DOWNLOAD EBOOKThis text is a detailed guide to the use of flow cytometry, immunohistochemistry, and molecular genetic techniques for diagnosis of hematologic neoplasms. Dr. Sun explains the principles of these techniques and demonstrates their utility in 39 clinical cases covering all important entities. Each case represents a comprehensive diagnostic approach including a clinical history and flow cytometric, immunohistochemical, and molecular genetic findings. Abundant full-color illustrations show histologic sections, immunohistochemical stains, bone marrow, peripheral blood, and body fluid smears, and each case includes a complete set of flow cytometric histograms. Over 100 tables compare and differentiate the diagnostic features of similar diseases. An image bank will be available on a companion Website.
Download or read book Flow Cytometry and Immunohistochemistry for Hematologic Neoplasms written by Tsieh Sun and published by Lippincott Williams & Wilkins. This book was released on 2008 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is a detailed guide to the use of flow cytometry, immunohistochemistry, and molecular genetic techniques for diagnosis of hematologic neoplasms. Dr. Sun explains the principles of these techniques and demonstrates their utility in 39 clinical cases covering all important entities. Each case represents a comprehensive diagnostic approach including a clinical history and flow cytometric, immunohistochemical, and molecular genetic findings. Abundant full-color illustrations show histologic sections, immunohistochemical stains, bone marrow, peripheral blood, and body fluid smears, and each case includes a complete set of flow cytometric histograms. Over 100 tables compare and differentiate the diagnostic features of similar diseases. An image bank will be available on a companion Website.
Author: Anna Porwit
Publisher: Cambridge University Press
Published: 2018-01-25
Total Pages: 248
ISBN-13: 1108548830
DOWNLOAD EBOOKMaster implementation of the techniques of flow cytometry in diagnosing complex haematological diseases and malignancies in patients, worldwide. Featuring World Health Organization recommendations on pre-analytical steps, instrument settings and panel construction, this invaluable manual offers invaluable support for those researching, practising and analyzing the cause of hematological malignancies. Authored by leading experts, this book puts flow-cytometry into everyday context. With a focus on multicolour panels, the manual provides readers an experienced understanding of effective, implementation techniques. Practitioners of all levels are offered a background in a variety of diseases presented alongside the most current methodology. Wide-ranging and comprehensive; detailed images of healthy blood, bone marrow and lymph-nodes are illustrated throughout, allowing for effective diagnosis. Through engaging with differential diagnoses, the manual offers an understanding of similar symptoms and mimicking malignancies, avoiding inaccurate results. Featuring in-depth descriptions of chronic diseases; users can reach accurate diagnosis, first time.
Download or read book Multiparameter Flow Cytometry in the Diagnosis of Hematologic Malignancies written by Anna Porwit and published by Cambridge University Press. This book was released on 2018-01-25 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master implementation of the techniques of flow cytometry in diagnosing complex haematological diseases and malignancies in patients, worldwide. Featuring World Health Organization recommendations on pre-analytical steps, instrument settings and panel construction, this invaluable manual offers invaluable support for those researching, practising and analyzing the cause of hematological malignancies. Authored by leading experts, this book puts flow-cytometry into everyday context. With a focus on multicolour panels, the manual provides readers an experienced understanding of effective, implementation techniques. Practitioners of all levels are offered a background in a variety of diseases presented alongside the most current methodology. Wide-ranging and comprehensive; detailed images of healthy blood, bone marrow and lymph-nodes are illustrated throughout, allowing for effective diagnosis. Through engaging with differential diagnoses, the manual offers an understanding of similar symptoms and mimicking malignancies, avoiding inaccurate results. Featuring in-depth descriptions of chronic diseases; users can reach accurate diagnosis, first time.
Author: Bernadette F. Rodak
Publisher: Elsevier Health Sciences
Published: 2013-12-27
Total Pages: 885
ISBN-13: 0323292690
DOWNLOAD EBOOKFeaturing hundreds of full-color photomicrographs, Hematology: Clinical Principles and Applications prepares you for a job in the clinical lab by exploring the essential aspects of hematology. It shows how to accurately identify cells, simplifies hemostasis and thrombosis concepts, and covers normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origins. This book also makes it easy to understand complementary testing areas such as flow cytometry, cytogenetics, and molecular diagnostics. Well-known authors Bernadette Rodak, George Fritsma, and Elaine Keohane cover everything from working in a hematology lab to the parts and functions of the cell to laboratory testing of blood cells and body fluid cells. Full-color illustrations make it easier to visualize complex concepts and show what you’ll encounter in the lab. Learning objectives begin each chapter, and review questions appear at the end. Instructions for lab procedures include sources of possible errors along with comments. Case studies provide opportunities to apply hematology concepts to real-life scenarios. Hematology instruments are described, compared, and contrasted. Coverage of hemostasis and thrombosis includes the development and function of platelets, the newest theories of normal coagulation, and clear discussions of platelet abnormalities and disorders of coagulation. A bulleted summary of important content appears at the end of every chapter. A glossary of key terms makes it easy to find and learn definitions. Hematology/hemostasis reference ranges are listed on the inside front and back covers for quick reference. Respected editors Bernadette Rodak, George Fritsma, and Elaine Keohane are well known in the hematology/clinical laboratory science world. Student resources on the companion Evolve website include the glossary, weblinks, and content updates. New content is added on basic cell biology and etiology of leukocyte neoplasias. Updated Molecular Diagnostics chapter keeps you current on techniques being used in the lab. Simplified hemostasis material ensures that you can understand this complex and important subject. Coverage of morphologic alteration of monocytes/macrophages is condensed into a table, as the disorders in this grouping are more of a biochemical nature with minimal hematologic evidence.
Download or read book Hematology - E-Book written by Bernadette F. Rodak and published by Elsevier Health Sciences. This book was released on 2013-12-27 with total page 885 pages. Available in PDF, EPUB and Kindle. Book excerpt: Featuring hundreds of full-color photomicrographs, Hematology: Clinical Principles and Applications prepares you for a job in the clinical lab by exploring the essential aspects of hematology. It shows how to accurately identify cells, simplifies hemostasis and thrombosis concepts, and covers normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origins. This book also makes it easy to understand complementary testing areas such as flow cytometry, cytogenetics, and molecular diagnostics. Well-known authors Bernadette Rodak, George Fritsma, and Elaine Keohane cover everything from working in a hematology lab to the parts and functions of the cell to laboratory testing of blood cells and body fluid cells. Full-color illustrations make it easier to visualize complex concepts and show what you’ll encounter in the lab. Learning objectives begin each chapter, and review questions appear at the end. Instructions for lab procedures include sources of possible errors along with comments. Case studies provide opportunities to apply hematology concepts to real-life scenarios. Hematology instruments are described, compared, and contrasted. Coverage of hemostasis and thrombosis includes the development and function of platelets, the newest theories of normal coagulation, and clear discussions of platelet abnormalities and disorders of coagulation. A bulleted summary of important content appears at the end of every chapter. A glossary of key terms makes it easy to find and learn definitions. Hematology/hemostasis reference ranges are listed on the inside front and back covers for quick reference. Respected editors Bernadette Rodak, George Fritsma, and Elaine Keohane are well known in the hematology/clinical laboratory science world. Student resources on the companion Evolve website include the glossary, weblinks, and content updates. New content is added on basic cell biology and etiology of leukocyte neoplasias. Updated Molecular Diagnostics chapter keeps you current on techniques being used in the lab. Simplified hemostasis material ensures that you can understand this complex and important subject. Coverage of morphologic alteration of monocytes/macrophages is condensed into a table, as the disorders in this grouping are more of a biochemical nature with minimal hematologic evidence.
Author: Tsieh Sun
Publisher: Lippincott Williams & Wilkins
Published: 2012-01-19
Total Pages: 449
ISBN-13: 1451180640
DOWNLOAD EBOOKImmunophenotyping is the most powerful tool in the routine diagnosis of hematologic neoplasms. Immunohistochemical technique is used in histology labs for this purpose, while flow cytometry is used in clinical labs. Although separately these 2 techniques are very useful in detecting lymphomas and leukemias, the combination of both creates a very powerful and definitive diagnostic tool. The addition of molecular genetics to the book makes it an all-encompassing reference text.
Download or read book Flow Cytometry, Immunohistochemistry, and Molecular Genetics for Hematologic Neoplasms written by Tsieh Sun and published by Lippincott Williams & Wilkins. This book was released on 2012-01-19 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunophenotyping is the most powerful tool in the routine diagnosis of hematologic neoplasms. Immunohistochemical technique is used in histology labs for this purpose, while flow cytometry is used in clinical labs. Although separately these 2 techniques are very useful in detecting lymphomas and leukemias, the combination of both creates a very powerful and definitive diagnostic tool. The addition of molecular genetics to the book makes it an all-encompassing reference text.
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Published: 2015-12-29
Total Pages: 473
ISBN-13: 0309377722
DOWNLOAD EBOOKGetting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.
Download or read book Improving Diagnosis in Health Care written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2015-12-29 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.
Author: Bernadette F. Rodak
Publisher: Elsevier Health Sciences
Published: 2007-01-01
Total Pages: 836
ISBN-13: 1416030069
DOWNLOAD EBOOKTextbook explores key aspects of hematology from normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origin. Includes a revised section on hemostasis and thrombosis. Case studies and chapter summaries are included.
Download or read book Hematology written by Bernadette F. Rodak and published by Elsevier Health Sciences. This book was released on 2007-01-01 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Textbook explores key aspects of hematology from normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origin. Includes a revised section on hemostasis and thrombosis. Case studies and chapter summaries are included.
