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Molecular Diagnostics in Dermatology and Dermatopathology

Author: Michael J. Murphy

Publisher: Springer Science & Business Media

Published: 2011-03-24

Total Pages: 480

ISBN-13: 1607611716

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Molecular Diagnostics in Dermatology and Dermatopathology presents the basics of molecular biology and molecular diagnostic methods most commonly used in the clinical laboratory, with an emphasis on the concepts and testing most relevant to dermatological diseases. Topics include the integration of newer diagnostic and prognostic techniques with ‘traditional’ histologic approaches, and discussions of regulatory, ethical, legal, economic issues and ‘newer’ technologies. This important diagnostic tool outlines the clinically relevant uses (i.e.; diagnostic, staging and/or prognostic) applications of these techniques in the field of dermatology. Molecular studies that investigate the pathogenesis of skin diseases will be excluded, unless they also have a direct diagnostic utility. The book will be of interest to practicing pathologists, dermatology and pathology residents, dermatologists, and dermatopathologists.

Book Synopsis Molecular Diagnostics in Dermatology and Dermatopathology by : Michael J. Murphy

Download or read book Molecular Diagnostics in Dermatology and Dermatopathology written by Michael J. Murphy and published by Springer Science & Business Media. This book was released on 2011-03-24 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Diagnostics in Dermatology and Dermatopathology presents the basics of molecular biology and molecular diagnostic methods most commonly used in the clinical laboratory, with an emphasis on the concepts and testing most relevant to dermatological diseases. Topics include the integration of newer diagnostic and prognostic techniques with ‘traditional’ histologic approaches, and discussions of regulatory, ethical, legal, economic issues and ‘newer’ technologies. This important diagnostic tool outlines the clinically relevant uses (i.e.; diagnostic, staging and/or prognostic) applications of these techniques in the field of dermatology. Molecular studies that investigate the pathogenesis of skin diseases will be excluded, unless they also have a direct diagnostic utility. The book will be of interest to practicing pathologists, dermatology and pathology residents, dermatologists, and dermatopathologists.

Molecular Diagnostics for Dermatology

Author: Gregory A. Hosler

Publisher: Springer Science & Business

Published: 2014-04-30

Total Pages: 370

ISBN-13: 364254066X

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Molecular diagnostics is an exploding field, and recent advances in our understanding of the molecular basis of disease have provided a platform for the development of new diagnostic tests as well as tests to predict tumor behavior and potential response to targeted therapy. This textbook provides a reference and practical guide to molecular diagnostics for dermatologists and dermatopathologists. It outlines our current understanding of the molecular underpinnings of dermatologic disease, describes the appropriate use of currently available molecular tests, and explains the interpretation of these tests in the context of diagnosis and management. Tests relating to various disorders are covered, including but not confined to melanoma, genodermatoses, and infectious disease. Pitfalls are highlighted and user-friendly algorithmic approaches, presented.

Book Synopsis Molecular Diagnostics for Dermatology by : Gregory A. Hosler

Download or read book Molecular Diagnostics for Dermatology written by Gregory A. Hosler and published by Springer Science & Business. This book was released on 2014-04-30 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular diagnostics is an exploding field, and recent advances in our understanding of the molecular basis of disease have provided a platform for the development of new diagnostic tests as well as tests to predict tumor behavior and potential response to targeted therapy. This textbook provides a reference and practical guide to molecular diagnostics for dermatologists and dermatopathologists. It outlines our current understanding of the molecular underpinnings of dermatologic disease, describes the appropriate use of currently available molecular tests, and explains the interpretation of these tests in the context of diagnosis and management. Tests relating to various disorders are covered, including but not confined to melanoma, genodermatoses, and infectious disease. Pitfalls are highlighted and user-friendly algorithmic approaches, presented.

Status Quo and Future Perspectives of Molecular Diagnostics in Dermatology

Author: Christoffer Gebhardt

Publisher:

Published: 2023

Total Pages: 0

ISBN-13:

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Abstract: Molecular diagnostics (MDx) has become an indispensable pillar of diagnostics in dermatology. Modern sequencing technologies allow for identification of rare genodermatoses, analysis of somatic mutations in melanoma are prerequisite for targeted therapies, and cutaneous infectious pathogens are quickly detected by PCR and other amplification methods. However, to push innovation in molecular diagnostics and tackle so far unmet clinical needs, research activities need to be bundled and the pipeline from idea to MDx product clearly rolled out. Only then, the requirements for technical validity and clinical utility of novel biomarkers can be fulfilled and the long-term vision of personalized medicine will be realized

Book Synopsis Status Quo and Future Perspectives of Molecular Diagnostics in Dermatology by : Christoffer Gebhardt

Download or read book Status Quo and Future Perspectives of Molecular Diagnostics in Dermatology written by Christoffer Gebhardt and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Molecular diagnostics (MDx) has become an indispensable pillar of diagnostics in dermatology. Modern sequencing technologies allow for identification of rare genodermatoses, analysis of somatic mutations in melanoma are prerequisite for targeted therapies, and cutaneous infectious pathogens are quickly detected by PCR and other amplification methods. However, to push innovation in molecular diagnostics and tackle so far unmet clinical needs, research activities need to be bundled and the pipeline from idea to MDx product clearly rolled out. Only then, the requirements for technical validity and clinical utility of novel biomarkers can be fulfilled and the long-term vision of personalized medicine will be realized

Update in Dermatopathology, An Issue of Dermatologic Clinics - E-Book

Author: Tammie Ferringer

Publisher: Elsevier Health Sciences

Published: 2012-10-30

Total Pages: 240

ISBN-13: 1455747173

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This issue covers the scope of dermatopathology, with articles including Advances in Molecular Diagnostics, Melanoma Staging, IHC in Dermatopathology, and New Directions in the field. The issue is rounded out with coverage of Dermatopathology Eduction and Dermatopathology and the Law.

Book Synopsis Update in Dermatopathology, An Issue of Dermatologic Clinics - E-Book by : Tammie Ferringer

Download or read book Update in Dermatopathology, An Issue of Dermatologic Clinics - E-Book written by Tammie Ferringer and published by Elsevier Health Sciences. This book was released on 2012-10-30 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue covers the scope of dermatopathology, with articles including Advances in Molecular Diagnostics, Melanoma Staging, IHC in Dermatopathology, and New Directions in the field. The issue is rounded out with coverage of Dermatopathology Eduction and Dermatopathology and the Law.

Molecular Dermatology

Author: Cristina Has

Publisher: Humana Press

Published: 2016-05-01

Total Pages: 474

ISBN-13: 9781493959778

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This Methods in Molecular Biology volume collects reliable protocols covering a wide range of techniques and experimental models, specific molecular assays and disease models, and provides overviews of diagnostic and research topics in molecular dermatology."

Book Synopsis Molecular Dermatology by : Cristina Has

Download or read book Molecular Dermatology written by Cristina Has and published by Humana Press. This book was released on 2016-05-01 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Methods in Molecular Biology volume collects reliable protocols covering a wide range of techniques and experimental models, specific molecular assays and disease models, and provides overviews of diagnostic and research topics in molecular dermatology."

Dermatophytes and Dermatophytoses

Author: Jean-Philippe Bouchara

Publisher: Springer Nature

Published: 2021-06-08

Total Pages: 519

ISBN-13: 3030674215

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This book provides a comprehensive overview on the most recent knowledge in dermatophytic infection biology. Topics covered range from taxonomy, biology and genetics of most common skin disease causing fungi over immunology of dermatophytosis to diagnosis and treatment approaches. Furthermore epidemiology of skin diseases caused by pathogenic fungi is discussed. The book is aimed at researchers and advanced students in infection biology, microbiology and dermatology.

Book Synopsis Dermatophytes and Dermatophytoses by : Jean-Philippe Bouchara

Download or read book Dermatophytes and Dermatophytoses written by Jean-Philippe Bouchara and published by Springer Nature. This book was released on 2021-06-08 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview on the most recent knowledge in dermatophytic infection biology. Topics covered range from taxonomy, biology and genetics of most common skin disease causing fungi over immunology of dermatophytosis to diagnosis and treatment approaches. Furthermore epidemiology of skin diseases caused by pathogenic fungi is discussed. The book is aimed at researchers and advanced students in infection biology, microbiology and dermatology.

Diagnostic Dermatopathology: A Guide to Ancillary Tests Beyond the H&E

Author: Gregory A Hosler

Publisher: JP Medical Ltd

Published: 2016-12-15

Total Pages: 8

ISBN-13: 1909836125

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The practice of dermatopathology has evolved from viewing predominantly haematoxylin and eosin (H&E)-stained sections through the microscope to include an array of more specialized tests. These are used as stand-alone tests or in addition to the H&E. Diagnostic Dermatopathology: A Guide to Ancillary Tests Beyond the H&E is a practical guide to the most important of these new diagnostic techniques. Aside from a brief review of H&E in the Introduction, the focus of the book is on the wide range of more recent ancillary tests commonly used by clinicians, including sections on special stains, immunohistochemistry, immunofluorescence, electron microscopy and molecular testing. Each section describes why each of these tests is performed, how to use them and how to interpret the results they provide. Abundantly illustrated with colour photographs, diagrams and algorithms Diagnostic Dermatopathology: A Guide to Ancillary Tests Beyond the H&E is packed with practical guidance on commonly-faced diagnostic dilemmas, how the tests described can be used to resolve them and how to avoid pitfalls in the diagnostic process. The book is an essential resource for trainee and practicing dermatopathologists, dermatologists and pathologists seeking an accessible guide to the diagnostic methods which are increasingly important in dermatopathology and which go beyond the H&E. Key features Covers the full range of diagnostic tests in dermatopathology, aside from H&E, with a focus on practical clinical information such as how to run the test, when to use it and how to interpret the results Includes special stains, immunohistochemistry, immunofluorescence, electron microscopy, molecular testing and point of care tests including potassium hydroxide preparations, mineral oil preparations, and Tzanck smears Single author with hand-picked specialist contributors provide a consistent approach to the subject, replete with diagnostic tips and clinical advice based on extensive personal experience

Book Synopsis Diagnostic Dermatopathology: A Guide to Ancillary Tests Beyond the H&E by : Gregory A Hosler

Download or read book Diagnostic Dermatopathology: A Guide to Ancillary Tests Beyond the H&E written by Gregory A Hosler and published by JP Medical Ltd. This book was released on 2016-12-15 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: The practice of dermatopathology has evolved from viewing predominantly haematoxylin and eosin (H&E)-stained sections through the microscope to include an array of more specialized tests. These are used as stand-alone tests or in addition to the H&E. Diagnostic Dermatopathology: A Guide to Ancillary Tests Beyond the H&E is a practical guide to the most important of these new diagnostic techniques. Aside from a brief review of H&E in the Introduction, the focus of the book is on the wide range of more recent ancillary tests commonly used by clinicians, including sections on special stains, immunohistochemistry, immunofluorescence, electron microscopy and molecular testing. Each section describes why each of these tests is performed, how to use them and how to interpret the results they provide. Abundantly illustrated with colour photographs, diagrams and algorithms Diagnostic Dermatopathology: A Guide to Ancillary Tests Beyond the H&E is packed with practical guidance on commonly-faced diagnostic dilemmas, how the tests described can be used to resolve them and how to avoid pitfalls in the diagnostic process. The book is an essential resource for trainee and practicing dermatopathologists, dermatologists and pathologists seeking an accessible guide to the diagnostic methods which are increasingly important in dermatopathology and which go beyond the H&E. Key features Covers the full range of diagnostic tests in dermatopathology, aside from H&E, with a focus on practical clinical information such as how to run the test, when to use it and how to interpret the results Includes special stains, immunohistochemistry, immunofluorescence, electron microscopy, molecular testing and point of care tests including potassium hydroxide preparations, mineral oil preparations, and Tzanck smears Single author with hand-picked specialist contributors provide a consistent approach to the subject, replete with diagnostic tips and clinical advice based on extensive personal experience

Non Invasive Diagnostic Techniques in Clinical Dermatology

Author: Enzo Berardesca

Publisher: Springer Science & Business Media

Published: 2013-12-02

Total Pages: 464

ISBN-13: 3642321097

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This book is a comprehensive but compact guide to the latest technical and technological developments in the growing field of non invasive diagnosis in clinical dermatology. Information is provided on the practical and technical characteristics of a wide range of equipment and methods for in vivo measurements that aid in the investigation of skin function, the evaluation of topically applied products and the monitoring of skin disease. Individual sections are devoted to imaging techniques, skin analysis, superficial skin analysis, skin mechanics, water and stratum corneum hydration and erythema and blood flow. All of the authors are experts in the field, with detailed knowledge of the techniques they describe. Non Invasive Diagnostic Techniques in Clinical Dermatology will be of value for all dermatologists, whether they are engaged in delivering patient care or in research programs, for cosmetic scientists and for biologists involved in skin research and product assessment.

Book Synopsis Non Invasive Diagnostic Techniques in Clinical Dermatology by : Enzo Berardesca

Download or read book Non Invasive Diagnostic Techniques in Clinical Dermatology written by Enzo Berardesca and published by Springer Science & Business Media. This book was released on 2013-12-02 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive but compact guide to the latest technical and technological developments in the growing field of non invasive diagnosis in clinical dermatology. Information is provided on the practical and technical characteristics of a wide range of equipment and methods for in vivo measurements that aid in the investigation of skin function, the evaluation of topically applied products and the monitoring of skin disease. Individual sections are devoted to imaging techniques, skin analysis, superficial skin analysis, skin mechanics, water and stratum corneum hydration and erythema and blood flow. All of the authors are experts in the field, with detailed knowledge of the techniques they describe. Non Invasive Diagnostic Techniques in Clinical Dermatology will be of value for all dermatologists, whether they are engaged in delivering patient care or in research programs, for cosmetic scientists and for biologists involved in skin research and product assessment.

Diagnostics and Therapy in Veterinary Dermatology

Author: Dawn Logas

Publisher: John Wiley & Sons

Published: 2021-10-08

Total Pages: 272

ISBN-13: 1119680638

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Diagnostics and Therapy in Veterinary Dermatology presents thorough coverage of the latest discoveries, drugs, and treatments for dermatologic conditions in animals. Chapters written by experts in each respective area of veterinary dermatology contain up-to-date information on new diagnostic tools and tests, autoimmune diseases, parasitic and fungal infections, medical management of acute and chronic conditions, alternative dermatologic therapies, and more. Offering practical solutions for both specialist and general practice veterinarians dealing with dermatology cases, this wide-ranging resource also addresses antibiotic resistance and misuse, the availability of foods for elimination diet trials, problems with generic drugs, emerging infectious diseases, and other important problems currently facing the profession. Throughout the text, veterinary practitioners are provided with real-world guidance on improving how they work up their dermatology cases and strengthening communication between the primary care veterinarian and the dermatologist. Edited by a leading board-certified dermatologist, this volume: Focuses on cats and dogs Includes numerous high-quality clinical photographs illustrating all key concepts Covers topics such as how to use your nursing staff to the fullest, the One Health movement, and how changing climate is increasing the spread of certain dermatologic diseases Discusses approaches for building a better working relationship between clients, primary care veterinarians and dermatologists Provides insights on the future of technology in the diagnosis and treatment of dermatologic diseases Covering the very latest developments in the field, Diagnostics and Therapy in Veterinary Dermatology is essential reading for veterinary dermatologists, veterinary students, and any veterinary general practitioner with a dermatology caseload.

Book Synopsis Diagnostics and Therapy in Veterinary Dermatology by : Dawn Logas

Download or read book Diagnostics and Therapy in Veterinary Dermatology written by Dawn Logas and published by John Wiley & Sons. This book was released on 2021-10-08 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnostics and Therapy in Veterinary Dermatology presents thorough coverage of the latest discoveries, drugs, and treatments for dermatologic conditions in animals. Chapters written by experts in each respective area of veterinary dermatology contain up-to-date information on new diagnostic tools and tests, autoimmune diseases, parasitic and fungal infections, medical management of acute and chronic conditions, alternative dermatologic therapies, and more. Offering practical solutions for both specialist and general practice veterinarians dealing with dermatology cases, this wide-ranging resource also addresses antibiotic resistance and misuse, the availability of foods for elimination diet trials, problems with generic drugs, emerging infectious diseases, and other important problems currently facing the profession. Throughout the text, veterinary practitioners are provided with real-world guidance on improving how they work up their dermatology cases and strengthening communication between the primary care veterinarian and the dermatologist. Edited by a leading board-certified dermatologist, this volume: Focuses on cats and dogs Includes numerous high-quality clinical photographs illustrating all key concepts Covers topics such as how to use your nursing staff to the fullest, the One Health movement, and how changing climate is increasing the spread of certain dermatologic diseases Discusses approaches for building a better working relationship between clients, primary care veterinarians and dermatologists Provides insights on the future of technology in the diagnosis and treatment of dermatologic diseases Covering the very latest developments in the field, Diagnostics and Therapy in Veterinary Dermatology is essential reading for veterinary dermatologists, veterinary students, and any veterinary general practitioner with a dermatology caseload.

Molecular Allergy Diagnostics

Author: Jörg Kleine-Tebbe

Publisher: Springer

Published: 2017-05-08

Total Pages: 537

ISBN-13: 3319424998

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This book, based on a recent German publication, offers an overview of basic data and recent developments in the groundbreaking field of molecular allergology. It comprehensively explores the origin and structure of single allergen molecules ("components") and their utility in improving the management of type I, IgE-mediated allergic reactions and disorders like allergic respiratory diseases, food allergies, and anaphylaxis. Highly specific testing, called component-resolved diagnostics, aims to identify and utilize single molecules. Over 200 single allergens from plant or animal sources have been applied to single or multiplex laboratory testing for the presence of allergen-specific IgE. This leap in assay sensitivity and specificity has led to three major advances in patient management: discrimination between primary allergic sensitization and complex cross-reactivity, recognition of IgE profiles for certain allergens and identification of patients most likely to benefit from allergen-specific immunotherapy. The book discusses in detail the benefits and limitations of this 21st century technology, and offers suggestions for the use of molecular allergology in routine clinical practice. It is a “must read” for physicians treating allergic patients as well as scientists interested in natural allergic molecules and their interactions with the human immune system.

Book Synopsis Molecular Allergy Diagnostics by : Jörg Kleine-Tebbe

Download or read book Molecular Allergy Diagnostics written by Jörg Kleine-Tebbe and published by Springer. This book was released on 2017-05-08 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, based on a recent German publication, offers an overview of basic data and recent developments in the groundbreaking field of molecular allergology. It comprehensively explores the origin and structure of single allergen molecules ("components") and their utility in improving the management of type I, IgE-mediated allergic reactions and disorders like allergic respiratory diseases, food allergies, and anaphylaxis. Highly specific testing, called component-resolved diagnostics, aims to identify and utilize single molecules. Over 200 single allergens from plant or animal sources have been applied to single or multiplex laboratory testing for the presence of allergen-specific IgE. This leap in assay sensitivity and specificity has led to three major advances in patient management: discrimination between primary allergic sensitization and complex cross-reactivity, recognition of IgE profiles for certain allergens and identification of patients most likely to benefit from allergen-specific immunotherapy. The book discusses in detail the benefits and limitations of this 21st century technology, and offers suggestions for the use of molecular allergology in routine clinical practice. It is a “must read” for physicians treating allergic patients as well as scientists interested in natural allergic molecules and their interactions with the human immune system.