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Molecular Mechanisms in Spermatogenesis

Author: C.Y. Cheng

Publisher: Springer Science & Business Media

Published: 2009-10-24

Total Pages: 289

ISBN-13: 0387095977

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In the past thirty years, significant advances have been made in the field of reproductive biology in unlocking the molecular and biochemical events that regulate spermatogenesis in the mammalian testis. It was possible because of the unprecedented breakthroughs in molecular biology, cell biology, immunology, and biochemistry. In this book entitled, Molecular Mechanisms in Spermatogenesis, a collection of chapters has been included written by colleagues on the latest development in the field using genomic and proteomic approaches to study spermatogenesis, as well as different mechanisms and/or molecules including environmental toxicants and transcription factors that regulate and/or affect spermatogenesis. The book begins with a chapter that provides the basic concept of cellular regulation of spermatogenesis. A few chapters are also dedicated to some of the latest findings on the Sertoli cell cytoskeleton and other molecules (e.g., proteases, adhesion proteins) that regulate spermatogenesis. These chapters contain thought-provoking discussions and concepts which shall be welcomed by investigators in the field. It is obvious that many of these concepts will be updated and some may be amended in the years to come. However, they will serve as a guide and the basis for investigation by scientists in the field.

Book Synopsis Molecular Mechanisms in Spermatogenesis by : C.Y. Cheng

Download or read book Molecular Mechanisms in Spermatogenesis written by C.Y. Cheng and published by Springer Science & Business Media. This book was released on 2009-10-24 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past thirty years, significant advances have been made in the field of reproductive biology in unlocking the molecular and biochemical events that regulate spermatogenesis in the mammalian testis. It was possible because of the unprecedented breakthroughs in molecular biology, cell biology, immunology, and biochemistry. In this book entitled, Molecular Mechanisms in Spermatogenesis, a collection of chapters has been included written by colleagues on the latest development in the field using genomic and proteomic approaches to study spermatogenesis, as well as different mechanisms and/or molecules including environmental toxicants and transcription factors that regulate and/or affect spermatogenesis. The book begins with a chapter that provides the basic concept of cellular regulation of spermatogenesis. A few chapters are also dedicated to some of the latest findings on the Sertoli cell cytoskeleton and other molecules (e.g., proteases, adhesion proteins) that regulate spermatogenesis. These chapters contain thought-provoking discussions and concepts which shall be welcomed by investigators in the field. It is obvious that many of these concepts will be updated and some may be amended in the years to come. However, they will serve as a guide and the basis for investigation by scientists in the field.

Molecular Mechanisms in Spermatogenesis

Author: C.Yan Cheng

Publisher: Springer

Published: 2022-08-30

Total Pages: 0

ISBN-13: 9783030777814

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This new edition provides an update on the molecular mechanisms that regulate spermatogenesis. In addition to the rodent as a study model, chapters also include research on studies in humans. It includes the latest approaches of studying spermatogenesis, such as the use of bioinformatics, molecular modeling and others which are not commonly found in published materials. It also reviews the latest developments in the field, such as studies on the role of regulatory RNAs on spermatogenesis. Due to the declining fertility rate among men, a brand new chapter highlights the impact of environmental toxicants on spermatogenesis.

Book Synopsis Molecular Mechanisms in Spermatogenesis by : C.Yan Cheng

Download or read book Molecular Mechanisms in Spermatogenesis written by C.Yan Cheng and published by Springer. This book was released on 2022-08-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition provides an update on the molecular mechanisms that regulate spermatogenesis. In addition to the rodent as a study model, chapters also include research on studies in humans. It includes the latest approaches of studying spermatogenesis, such as the use of bioinformatics, molecular modeling and others which are not commonly found in published materials. It also reviews the latest developments in the field, such as studies on the role of regulatory RNAs on spermatogenesis. Due to the declining fertility rate among men, a brand new chapter highlights the impact of environmental toxicants on spermatogenesis.

Molecular Mechanisms in Spermatogenesis

Author: C.Yan Cheng

Publisher:

Published: 2021

Total Pages: 0

ISBN-13: 9783030777807

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Book Synopsis Molecular Mechanisms in Spermatogenesis by : C.Yan Cheng

Download or read book Molecular Mechanisms in Spermatogenesis written by C.Yan Cheng and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition provides an update on the molecular mechanisms that regulate spermatogenesis. In addition to the rodent as a study model, chapters also include research on studies in humans. It includes the latest approaches of studying spermatogenesis, such as the use of bioinformatics, molecular modeling and others which are not commonly found in published materials. It also reviews the latest developments in the field, such as studies on the role of regulatory RNAs on spermatogenesis. Due to the declining fertility rate among men, a brand new chapter highlights the impact of environmental toxicants on spermatogenesis.

Spermatogenesis

Author: Gladys Robinson

Publisher: Nova Science Publishers

Published: 2016

Total Pages: 0

ISBN-13: 9781634847155

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Spermatogenesis is a tightly regulated cellular renovation and differentiation process. It consists of self-renewal and differentiation of spermatogonial stem cells (SSCs), spermatocytic meiosis and spermiogenesis; each of these processes is essential to the continuous, successful production of male gametes. During spermiogenesis, haploid spermatids undergo extensive cellular, molecular and morphological changes, including acrosome biogenesis, flagellum development, cytoplasmic reorganization and chromatin condensation. These changes ultimately result in mature spermatozoa with an acrosome-covered head and motile tail. In this book, Chapter One summarizes the progress that has been made in understanding the molecular mechanisms underlying acrosome biogenesis, and the authors discuss the potential directions of future investigations of this process. Chapter Two briefly addresses the basics of spermatogenesis and the synthesis of ncRNAs, and then the authors discuss the recent progress in understanding of the functions of miRNAs, endo-siRNAs, piRNAs and lncRNAs in the regulation of spermatogenesis. Chapter Three provides a review of the current literature on testicular immunoregulation and its underlying mechanisms, along with its effect on testicular functions.

Book Synopsis Spermatogenesis by : Gladys Robinson

Download or read book Spermatogenesis written by Gladys Robinson and published by Nova Science Publishers. This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spermatogenesis is a tightly regulated cellular renovation and differentiation process. It consists of self-renewal and differentiation of spermatogonial stem cells (SSCs), spermatocytic meiosis and spermiogenesis; each of these processes is essential to the continuous, successful production of male gametes. During spermiogenesis, haploid spermatids undergo extensive cellular, molecular and morphological changes, including acrosome biogenesis, flagellum development, cytoplasmic reorganization and chromatin condensation. These changes ultimately result in mature spermatozoa with an acrosome-covered head and motile tail. In this book, Chapter One summarizes the progress that has been made in understanding the molecular mechanisms underlying acrosome biogenesis, and the authors discuss the potential directions of future investigations of this process. Chapter Two briefly addresses the basics of spermatogenesis and the synthesis of ncRNAs, and then the authors discuss the recent progress in understanding of the functions of miRNAs, endo-siRNAs, piRNAs and lncRNAs in the regulation of spermatogenesis. Chapter Three provides a review of the current literature on testicular immunoregulation and its underlying mechanisms, along with its effect on testicular functions.

Sertoli Cell Biology

Author: Michael D. Griswold

Publisher: Academic Press

Published: 2014-11-19

Total Pages: 488

ISBN-13: 012417048X

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Sertoli Cell Biology, Second Edition summarizes the progress since the last edition and emphasizes the new information available on Sertoli/germ cell interactions. This information is especially timely since the progress in the past few years has been exceptional and it relates to control of sperm production in vivo and in vitro. Fully revised Written by experts in the field Summarizes 10 years of research Contains clear explanations and summaries Provides a summary of references over the last 10 years

Book Synopsis Sertoli Cell Biology by : Michael D. Griswold

Download or read book Sertoli Cell Biology written by Michael D. Griswold and published by Academic Press. This book was released on 2014-11-19 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sertoli Cell Biology, Second Edition summarizes the progress since the last edition and emphasizes the new information available on Sertoli/germ cell interactions. This information is especially timely since the progress in the past few years has been exceptional and it relates to control of sperm production in vivo and in vitro. Fully revised Written by experts in the field Summarizes 10 years of research Contains clear explanations and summaries Provides a summary of references over the last 10 years

Endocrinology of the Testis and Male Reproduction

Author: Manuela Simoni

Publisher: Springer

Published: 2017-09-18

Total Pages: 1364

ISBN-13: 9783319444406

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This book provides a comprehensive overview of endocrinology of the male reproductive system, explaining how it works and how, sometimes, it fails to work. World-class specialists present state of the art knowledge on all aspects, including anatomy, physiology, molecular biology, genetics, pathophysiology, clinical manifestations of testicular diseases, endocrine aspects of andrological and sexual diseases, and therapy. Extensive consideration is given to sexual development, testicular function, the clinical approach to disorders of male reproduction, male hypogonadism, sexual dysfunction, and male infertility. In addition, sociodemographic, psychological, and ethical aspects of male reproductive disorders are discussed. The book is intended as a major reference for endocrinologists, andrologists, and sexologists, as well as basic and clinical scientists. It is published as part of the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.

Book Synopsis Endocrinology of the Testis and Male Reproduction by : Manuela Simoni

Download or read book Endocrinology of the Testis and Male Reproduction written by Manuela Simoni and published by Springer. This book was released on 2017-09-18 with total page 1364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of endocrinology of the male reproductive system, explaining how it works and how, sometimes, it fails to work. World-class specialists present state of the art knowledge on all aspects, including anatomy, physiology, molecular biology, genetics, pathophysiology, clinical manifestations of testicular diseases, endocrine aspects of andrological and sexual diseases, and therapy. Extensive consideration is given to sexual development, testicular function, the clinical approach to disorders of male reproduction, male hypogonadism, sexual dysfunction, and male infertility. In addition, sociodemographic, psychological, and ethical aspects of male reproductive disorders are discussed. The book is intended as a major reference for endocrinologists, andrologists, and sexologists, as well as basic and clinical scientists. It is published as part of the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.

Molecular Biology of the Male Reproductive System

Author: David de Kretser

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 502

ISBN-13: 008091764X

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Written by experts in their respective fields, this book reviews the expanding knowledge concerning the mechanisms regulating male reproduction at the molecular and cellular levels. It covers the development of the testes and regulatory controls for spermatogenesis and steroidogenesis, and it considers aspects of Sertoli cell function. Areas of emphasis include communication between the various cell types involved in reproduction by hormone and growth factors and the mechanisms by which these factors regulate gene expression. A number of mammalian systems, including humans, are covered. The carefully selected authors provide a clear synopsis of the concepts in each area as well as the latest references, enabling the reader to investigate the topic further. This book is of interest to those seeking an understanding of the regulatory mechanisms in male reproduction and is written for the graduate and postgraduate levels. Key Features * Provides up-to-date reviews of the molecular and cellular biology of male reproduction * Includes chapters on the developmental biology of the testes * Links conventional hormonal control of testicular function with the evolving role of growth factors and proto-oncogenes

Book Synopsis Molecular Biology of the Male Reproductive System by : David de Kretser

Download or read book Molecular Biology of the Male Reproductive System written by David de Kretser and published by Elsevier. This book was released on 2012-12-02 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts in their respective fields, this book reviews the expanding knowledge concerning the mechanisms regulating male reproduction at the molecular and cellular levels. It covers the development of the testes and regulatory controls for spermatogenesis and steroidogenesis, and it considers aspects of Sertoli cell function. Areas of emphasis include communication between the various cell types involved in reproduction by hormone and growth factors and the mechanisms by which these factors regulate gene expression. A number of mammalian systems, including humans, are covered. The carefully selected authors provide a clear synopsis of the concepts in each area as well as the latest references, enabling the reader to investigate the topic further. This book is of interest to those seeking an understanding of the regulatory mechanisms in male reproduction and is written for the graduate and postgraduate levels. Key Features * Provides up-to-date reviews of the molecular and cellular biology of male reproduction * Includes chapters on the developmental biology of the testes * Links conventional hormonal control of testicular function with the evolving role of growth factors and proto-oncogenes

Molecular Signaling in Spermatogenesis and Male Infertility

Author: Rajender Singh

Publisher: CRC Press

Published: 2019-11-06

Total Pages: 338

ISBN-13: 0429534426

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Spermatogenesis involves the coordination of a number of signaling pathways, which culminate into production of sperm. Its failure results in male factor infertility, which can be due to hormonal, environmental, genetic or other unknown factors. This book includes chapters on most of the signaling pathways known to contribute to spermatogenesis. Latest research in germ cell signaling like the role of small RNAs in spermatogenesis is also discussed. This book aims to serve as a reference for both clinicians and researchers, explaining possible causes of infertility and exploring various treatment methods for management through the basic understanding of the role of molecular signaling. Key Features Discusses the signaling pathways that contribute to successful spermatogenesis Covers comprehensive information about Spermatogenesis at one place Explores the vital aspects of male fertility and infertility Explains the epigenetic regulation of germ cell development and fertility Highlights the translational opportunities in molecular signaling in testis

Book Synopsis Molecular Signaling in Spermatogenesis and Male Infertility by : Rajender Singh

Download or read book Molecular Signaling in Spermatogenesis and Male Infertility written by Rajender Singh and published by CRC Press. This book was released on 2019-11-06 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spermatogenesis involves the coordination of a number of signaling pathways, which culminate into production of sperm. Its failure results in male factor infertility, which can be due to hormonal, environmental, genetic or other unknown factors. This book includes chapters on most of the signaling pathways known to contribute to spermatogenesis. Latest research in germ cell signaling like the role of small RNAs in spermatogenesis is also discussed. This book aims to serve as a reference for both clinicians and researchers, explaining possible causes of infertility and exploring various treatment methods for management through the basic understanding of the role of molecular signaling. Key Features Discusses the signaling pathways that contribute to successful spermatogenesis Covers comprehensive information about Spermatogenesis at one place Explores the vital aspects of male fertility and infertility Explains the epigenetic regulation of germ cell development and fertility Highlights the translational opportunities in molecular signaling in testis

The Sertoli Cell

Author: Lonnie Dee Russell

Publisher:

Published: 1993

Total Pages: 840

ISBN-13:

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Book Synopsis The Sertoli Cell by : Lonnie Dee Russell

Download or read book The Sertoli Cell written by Lonnie Dee Russell and published by . This book was released on 1993 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Infertility in the Male

Author: Larry I. Lipshultz

Publisher: Cambridge University Press

Published: 2009-09-24

Total Pages: 691

ISBN-13: 1139483242

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The new edition of this canonical text on male reproductive medicine will cement the book's market-leading position. Practitioners across many specialties - including urologists, gynecologists, reproductive endocrinologists, medical endocrinologists and many in internal medicine and family practice – will see men with suboptimal fertility and reproductive problems. The book provides an excellent source of timely, well-considered information for those training in this young and rapidly evolving field. While several recent books provide targeted 'cookbooks' for those in a male reproductive laboratory, or quick reference for practising generalists, the modern, comprehensive reference providing both a background for male reproductive medicine as well as clinical practice information based on that foundation has been lacking until now. The book has been extensively revised with a particular focus on modern molecular medicine. Appropriate therapeutic interventions are highlighted throughout.

Book Synopsis Infertility in the Male by : Larry I. Lipshultz

Download or read book Infertility in the Male written by Larry I. Lipshultz and published by Cambridge University Press. This book was released on 2009-09-24 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this canonical text on male reproductive medicine will cement the book's market-leading position. Practitioners across many specialties - including urologists, gynecologists, reproductive endocrinologists, medical endocrinologists and many in internal medicine and family practice – will see men with suboptimal fertility and reproductive problems. The book provides an excellent source of timely, well-considered information for those training in this young and rapidly evolving field. While several recent books provide targeted 'cookbooks' for those in a male reproductive laboratory, or quick reference for practising generalists, the modern, comprehensive reference providing both a background for male reproductive medicine as well as clinical practice information based on that foundation has been lacking until now. The book has been extensively revised with a particular focus on modern molecular medicine. Appropriate therapeutic interventions are highlighted throughout.