Nerve-Driven Immunity

Nerve-Driven Immunity

Author: Mia Levite

Publisher: Springer Science & Business Media

Published: 2012-02-16

Total Pages: 374

ISBN-13: 370910887X

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“Nerve-Driven Immunity: Neurotransmitters and Neuropeptides in the Immune System” summarizes, analyzes and sheds new light on an unrecognized, yet very important role of key neurotransmitters and neuropeptides in the immune system. Each chapter of the book deals with a different neurotransmitter/neuropeptide from the following list: Dopamine, Adrenaline, Noradrenaline, Acetylcholine, Glutamate, GABA, Somatostatin, Neuropeptide Y (NPY), Vasoactive intestinal polypeptide (VIP), Calcitonin gene related peptide (CGRP), Opioids and Cannabinoids. For each of these neurotransmitters/neuropeptides, the following four topics are discussed: The specific receptors for the neurotransmitter/neuropeptide expressed in various types of immune cells The direct effects induced by the neurotransmitter/neuropeptide in various types of immune cells (either resting or activated), and the specific immune functions and features it activates/elevates or rather inhibits in specific concentrations The production of the neurotransmitter/neuropeptide in, and its release by, various types of immune cells The involvement of the neurotransmitter/neuropeptide in various diseases of the immune system (among them autoimmune diseases, immunodeficiency diseases and hematological cancers) The book includes many original figures, overview tables, and proposed models of events which are instrumental, enriching and stimulating for the reader. In light of the above-mentioned aspects, “Nerve-Driven Immunity: Neurotransmitters and Neuropeptides in the Immune System” is ideally suited as a textbook for new courses in Immunology, Neurology, Neuro-immunology or Pharmacology. The book chapters were written by highly skilled authors from 10 countries: the USA, the United Kingdom, Italy, Israel, Sweden, France, Germany, Spain, Serbia and Romania. “Nerve-Driven Immunity” is a term first coined by Dr. Mia Levite (the editor of the book).


Book Synopsis Nerve-Driven Immunity by : Mia Levite

Download or read book Nerve-Driven Immunity written by Mia Levite and published by Springer Science & Business Media. This book was released on 2012-02-16 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Nerve-Driven Immunity: Neurotransmitters and Neuropeptides in the Immune System” summarizes, analyzes and sheds new light on an unrecognized, yet very important role of key neurotransmitters and neuropeptides in the immune system. Each chapter of the book deals with a different neurotransmitter/neuropeptide from the following list: Dopamine, Adrenaline, Noradrenaline, Acetylcholine, Glutamate, GABA, Somatostatin, Neuropeptide Y (NPY), Vasoactive intestinal polypeptide (VIP), Calcitonin gene related peptide (CGRP), Opioids and Cannabinoids. For each of these neurotransmitters/neuropeptides, the following four topics are discussed: The specific receptors for the neurotransmitter/neuropeptide expressed in various types of immune cells The direct effects induced by the neurotransmitter/neuropeptide in various types of immune cells (either resting or activated), and the specific immune functions and features it activates/elevates or rather inhibits in specific concentrations The production of the neurotransmitter/neuropeptide in, and its release by, various types of immune cells The involvement of the neurotransmitter/neuropeptide in various diseases of the immune system (among them autoimmune diseases, immunodeficiency diseases and hematological cancers) The book includes many original figures, overview tables, and proposed models of events which are instrumental, enriching and stimulating for the reader. In light of the above-mentioned aspects, “Nerve-Driven Immunity: Neurotransmitters and Neuropeptides in the Immune System” is ideally suited as a textbook for new courses in Immunology, Neurology, Neuro-immunology or Pharmacology. The book chapters were written by highly skilled authors from 10 countries: the USA, the United Kingdom, Italy, Israel, Sweden, France, Germany, Spain, Serbia and Romania. “Nerve-Driven Immunity” is a term first coined by Dr. Mia Levite (the editor of the book).


Neuro-Immune Interactions in Inflammation and Autoimmunity

Neuro-Immune Interactions in Inflammation and Autoimmunity

Author: Valentin A. Pavlov

Publisher: Frontiers Media SA

Published: 2018-07-24

Total Pages: 222

ISBN-13: 2889455335

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The nervous system plays an important role in the regulation of immunity and inflammation. On the other hand unbalanced immune responses in inflammatory and autoimmune conditions may have a deleterious impact on neuronal integrity and brain function. Recent studies have characterized neural pathways communicating peripheral inflammatory signals to the CNS, and brain- and spinal cord-derived circuitries controlling various innate and adaptive immune responses and inflammation. A prototypical neural reflex circuit that regulates immunity and inflammation is the vagus nerve-based “inflammatory reflex”. Ongoing research has revealed cellular and molecular mechanisms underlying these neural circuits and indicated new therapeutic approaches in inflammatory and autoimmune disorders. Pharmacological and bioelectronic modulation of neural circuitry has been successfully explored in preclinical settings of sepsis, arthritis, inflammatory bowel disease, obesity-driven disorders, diabetes and other diseases. These studies paved the way to successful clinical trials with bioelectronic neuronal modulation in rheumatoid arthritis and inflammatory bowel disease. Dysregulated release of cytokines and other inflammatory molecules may have a severe impact on brain function. Brain inflammation (neuroinflammation), imbalances in brain neuronal integrity and neurotransmitter systems, and cognitive impairment are characteristic features of post-operative conditions, sepsis, liver diseases, diabetes and other disorders characterized by immune and metabolic dysregulation. Derangements in cytokine release also play a pivotal role in depression. Characteristic brain reactive antibodies in autoimmune conditions, including systemic lupus erythematosus and neuromyelitis optica, significantly contribute to brain pathology and cognitive impairment. These studies, and the simultaneous characterization of neuro-protective cytokines, identified new therapeutic approaches for treating neurological complications in inflammatory and autoimmune disorders. This Frontiers Research Topic is a forum for publishing research findings and methodological and conceptual advances at the intersection of immunology and neuroscience. We hope that presenting new insight into bi-directional neuro-immune communication in inflammation and autoimmunity will foster further collaborations and facilitate the development of new efficient therapeutic strategies.


Book Synopsis Neuro-Immune Interactions in Inflammation and Autoimmunity by : Valentin A. Pavlov

Download or read book Neuro-Immune Interactions in Inflammation and Autoimmunity written by Valentin A. Pavlov and published by Frontiers Media SA. This book was released on 2018-07-24 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nervous system plays an important role in the regulation of immunity and inflammation. On the other hand unbalanced immune responses in inflammatory and autoimmune conditions may have a deleterious impact on neuronal integrity and brain function. Recent studies have characterized neural pathways communicating peripheral inflammatory signals to the CNS, and brain- and spinal cord-derived circuitries controlling various innate and adaptive immune responses and inflammation. A prototypical neural reflex circuit that regulates immunity and inflammation is the vagus nerve-based “inflammatory reflex”. Ongoing research has revealed cellular and molecular mechanisms underlying these neural circuits and indicated new therapeutic approaches in inflammatory and autoimmune disorders. Pharmacological and bioelectronic modulation of neural circuitry has been successfully explored in preclinical settings of sepsis, arthritis, inflammatory bowel disease, obesity-driven disorders, diabetes and other diseases. These studies paved the way to successful clinical trials with bioelectronic neuronal modulation in rheumatoid arthritis and inflammatory bowel disease. Dysregulated release of cytokines and other inflammatory molecules may have a severe impact on brain function. Brain inflammation (neuroinflammation), imbalances in brain neuronal integrity and neurotransmitter systems, and cognitive impairment are characteristic features of post-operative conditions, sepsis, liver diseases, diabetes and other disorders characterized by immune and metabolic dysregulation. Derangements in cytokine release also play a pivotal role in depression. Characteristic brain reactive antibodies in autoimmune conditions, including systemic lupus erythematosus and neuromyelitis optica, significantly contribute to brain pathology and cognitive impairment. These studies, and the simultaneous characterization of neuro-protective cytokines, identified new therapeutic approaches for treating neurological complications in inflammatory and autoimmune disorders. This Frontiers Research Topic is a forum for publishing research findings and methodological and conceptual advances at the intersection of immunology and neuroscience. We hope that presenting new insight into bi-directional neuro-immune communication in inflammation and autoimmunity will foster further collaborations and facilitate the development of new efficient therapeutic strategies.


Janeway's Immunobiology

Janeway's Immunobiology

Author: Kenneth Murphy

Publisher: Garland Science

Published: 2010-06-22

Total Pages:

ISBN-13: 9780815344575

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The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.


Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.


Neuroimmunity

Neuroimmunity

Author: Michal Schwartz

Publisher: Yale University Press

Published: 2015-01-01

Total Pages: 316

ISBN-13: 0300203470

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Pathbreaking research offers new hope for treating brain diseases and injuries and for maintaining brain health even into old age In the past, the brain was considered an autonomous organ, self-contained and completely separate from the body's immune system. But over the past twenty years, neuroimmunologist Michal Schwartz, together with her research team, not only has overturned this misconception but has brought to light revolutionary new understandings of brain health and repair. In this book Schwartz describes her research journey, her experiments, and the triumphs and setbacks that led to the discovery of connections between immune system and brain. Michal Schwartz, with Anat London, also explains the significance of the findings for future treatments of brain disorders and injuries, spinal cord injuries, glaucoma, depression, and other conditions such as brain aging and Alzheimer's and Parkinson's diseases. Scientists, physicians, medical students, and all readers with an interest in brain function and its relationship to the immune system in health and disease will find this book a valuable resource. With general readers in mind, the authors provide a useful primer to explain scientific terms and concepts discussed in the book.


Book Synopsis Neuroimmunity by : Michal Schwartz

Download or read book Neuroimmunity written by Michal Schwartz and published by Yale University Press. This book was released on 2015-01-01 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathbreaking research offers new hope for treating brain diseases and injuries and for maintaining brain health even into old age In the past, the brain was considered an autonomous organ, self-contained and completely separate from the body's immune system. But over the past twenty years, neuroimmunologist Michal Schwartz, together with her research team, not only has overturned this misconception but has brought to light revolutionary new understandings of brain health and repair. In this book Schwartz describes her research journey, her experiments, and the triumphs and setbacks that led to the discovery of connections between immune system and brain. Michal Schwartz, with Anat London, also explains the significance of the findings for future treatments of brain disorders and injuries, spinal cord injuries, glaucoma, depression, and other conditions such as brain aging and Alzheimer's and Parkinson's diseases. Scientists, physicians, medical students, and all readers with an interest in brain function and its relationship to the immune system in health and disease will find this book a valuable resource. With general readers in mind, the authors provide a useful primer to explain scientific terms and concepts discussed in the book.


Inflammation, 4 Volume Set

Inflammation, 4 Volume Set

Author: Jean-Marc Cavaillon

Publisher: John Wiley & Sons

Published: 2018-02-20

Total Pages: 1818

ISBN-13: 3527338993

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The leading reference on this topic of increasing medical relevance is unique in offering unparalleled coverage. The editors are among the most respected researchers in inflammation worldwide and here have put together a prestigious team of contributors. Starting with the molecular basis of inflammation, from cytokines via the innate immune system to the different kinds of inflammatory cells, they continue with the function of inflammation in infectious disease before devoting a large section to the relationship between inflammation and chronic diseases. The book concludes with wound and tissue healing and options for therapeutic interventions. A must have for clinicians and biomedical researchers alike.


Book Synopsis Inflammation, 4 Volume Set by : Jean-Marc Cavaillon

Download or read book Inflammation, 4 Volume Set written by Jean-Marc Cavaillon and published by John Wiley & Sons. This book was released on 2018-02-20 with total page 1818 pages. Available in PDF, EPUB and Kindle. Book excerpt: The leading reference on this topic of increasing medical relevance is unique in offering unparalleled coverage. The editors are among the most respected researchers in inflammation worldwide and here have put together a prestigious team of contributors. Starting with the molecular basis of inflammation, from cytokines via the innate immune system to the different kinds of inflammatory cells, they continue with the function of inflammation in infectious disease before devoting a large section to the relationship between inflammation and chronic diseases. The book concludes with wound and tissue healing and options for therapeutic interventions. A must have for clinicians and biomedical researchers alike.


Autoimmune Neurology

Autoimmune Neurology

Author:

Publisher: Elsevier

Published: 2016-03-11

Total Pages: 568

ISBN-13: 0444634460

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Autoimmune Neurology presents the latest information on autoimmune neurologic disease, the immune response to the body where organs run wild, causing the immune system to attack itself. Autoimmunity is a main element in numerous nervous system diseases and can target any structure within the central or peripheral nervous system. Over the past 20 years, significant advances in our understanding of the pathophysiology of autoimmune disorders, including the use of biomarkers has led to new diagnosis and treatment options. Neurologic conditions associated with autoimmune reactions include dementia, neuromuscular disease, epilepsy, sleep disorders, diabetes, and other common neurologic disorders and disease. This current tutorial-reference will be a must-have title for clinical neurologists, research neurologists, neuroscientists, and any medical professional working with autoimmune disease and disorders. Includes comprehensive coverage of autoimmune neurology Details the latest techniques for the study, diagnosis, and treatment of diseases and disorders, including dementia, neuromuscular disease, epilepsy, and sleep disorders Presents a focused reference for clinical practitioners and the clinical neurology and neurology research communities


Book Synopsis Autoimmune Neurology by :

Download or read book Autoimmune Neurology written by and published by Elsevier. This book was released on 2016-03-11 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autoimmune Neurology presents the latest information on autoimmune neurologic disease, the immune response to the body where organs run wild, causing the immune system to attack itself. Autoimmunity is a main element in numerous nervous system diseases and can target any structure within the central or peripheral nervous system. Over the past 20 years, significant advances in our understanding of the pathophysiology of autoimmune disorders, including the use of biomarkers has led to new diagnosis and treatment options. Neurologic conditions associated with autoimmune reactions include dementia, neuromuscular disease, epilepsy, sleep disorders, diabetes, and other common neurologic disorders and disease. This current tutorial-reference will be a must-have title for clinical neurologists, research neurologists, neuroscientists, and any medical professional working with autoimmune disease and disorders. Includes comprehensive coverage of autoimmune neurology Details the latest techniques for the study, diagnosis, and treatment of diseases and disorders, including dementia, neuromuscular disease, epilepsy, and sleep disorders Presents a focused reference for clinical practitioners and the clinical neurology and neurology research communities


Insect Immunology

Insect Immunology

Author: Nancy E. Beckage

Publisher: Academic Press

Published: 2011-04-28

Total Pages: 367

ISBN-13: 0080556337

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This work is the first book-length publication on the topic of insect immunology since 1991, complementing earlier works by offering a fresh perspective on current research. Interactions of host immune systems with both parasites and pathogens are presented in detail, as well as the genomics and proteomics, approaches which have been lacking in other publications. Beckage provides comprehensive coverage of topics important to medical researchers, including Drosophila as a model for studying cellular and humoral immune mechanisms, biochemical mediators of immunity, and insect blood cells and their functions. Encompasses the most important topics of insect immunology including mechanisms, genes, proteins, evolution and phylogeny Provides comprehensive coverage of topics important to medical researchers including Drosophila as a model for studying cellular and humoral immune mechanisms, biochemical mediators of immunity, and insect blood cells and their functions Most up-to-date information published with contributions from international leaders in the field


Book Synopsis Insect Immunology by : Nancy E. Beckage

Download or read book Insect Immunology written by Nancy E. Beckage and published by Academic Press. This book was released on 2011-04-28 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work is the first book-length publication on the topic of insect immunology since 1991, complementing earlier works by offering a fresh perspective on current research. Interactions of host immune systems with both parasites and pathogens are presented in detail, as well as the genomics and proteomics, approaches which have been lacking in other publications. Beckage provides comprehensive coverage of topics important to medical researchers, including Drosophila as a model for studying cellular and humoral immune mechanisms, biochemical mediators of immunity, and insect blood cells and their functions. Encompasses the most important topics of insect immunology including mechanisms, genes, proteins, evolution and phylogeny Provides comprehensive coverage of topics important to medical researchers including Drosophila as a model for studying cellular and humoral immune mechanisms, biochemical mediators of immunity, and insect blood cells and their functions Most up-to-date information published with contributions from international leaders in the field


Immunoneurology

Immunoneurology

Author: Michel Chofflon

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 265

ISBN-13: 3642611915

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A considerable amount of information has been gathered in the field of immunoneurology over recent years. This knowledge about modifications in the pathways of neuroimmune diseases has enabled the development of new therapies. In this volume leading experts present the state of the art in the field, covering all aspects from basic science to the development of better therapies.


Book Synopsis Immunoneurology by : Michel Chofflon

Download or read book Immunoneurology written by Michel Chofflon and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: A considerable amount of information has been gathered in the field of immunoneurology over recent years. This knowledge about modifications in the pathways of neuroimmune diseases has enabled the development of new therapies. In this volume leading experts present the state of the art in the field, covering all aspects from basic science to the development of better therapies.


The Autoimmune Brain

The Autoimmune Brain

Author: David S. Younger

Publisher: Rowman & Littlefield

Published: 2019-11-10

Total Pages: 289

ISBN-13: 1538117711

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There are millions of people who experience issues related to brain health—depression, attention issues, anxiety, forgetfulness, fatigue, and even chronic pain—yet can’t figure out what’s causing their problems and can’t find any relief. They may have seen a myriad of doctors, many of whom do not take their complaints seriously, or worse, turn to the easy, often inappropriate fix of antidepressants or anti-anxiety medications. Traditional medications, supplements, or other therapies haven’t worked. No matter what their age—from children to teens or seniors—people and their loved ones are frustrated, scared, and confused by their continued poor health. Countless others display severe psychiatric symptoms that seem to come out of nowhere, ranging from tics, obsessive-compulsive behaviors and anxiety, to depression, bipolar-like mood swings, and even borderline personality disorder and suicidal ideas. Sometimes, the people affected are the only ones that notices a change to the way they think or feel, and they suffer in silence. Or, they reach out to try to get help, and are all too frequently misdiagnosed. David Younger, a world-renowned physician, provides relief to these patients and their families. His diagnostic techniques and treatment protocols will help readers identify the true cause of their symptoms and put them on a clear path to healing so they no longer feel unbalanced, out of control, forgetful, and exhausted. The Autoimmune Brain connects common brain health symptoms to the changes in the immune system, and particularly bacterial, viral, and parasitic infections. Younger explains his groundbreaking research and adds a new component: how traumatic stress (whether physical or emotional) and genetics affects this same triad as inextricable factors in initiating disease and brain health symptoms. In fact, a change in personality, behavior, coping style, and one’s emotional state may be the first clue that there is a health problem brewing somewhere else in the body. Readers will find new answers to troubling conditions, including: Alzheimer’s disease; Anxiety; Arthritis; Autism; Autonomic disturbances; Bacterial and viral infections; Bipolar Disorder; Cancer; Celiac disease and gluten intolerances; Chronic Fatigue Syndrome (now referred to as Systemic Exertion Intolerance Disease); Chronic Pain; Dementia; Depression; Endocrine Disorders; Immune modulatory therapy using IVIg; Lyme disease and co-infections; Mast cell activation syndrome; Medical cannabis; Obsessive Compulsive Disorder; Orthostatic hypotension; Peripheral Neuropathy; Porphyria; Post-Traumatic Stress Disorder; and Postural orthostatic tachycardia.


Book Synopsis The Autoimmune Brain by : David S. Younger

Download or read book The Autoimmune Brain written by David S. Younger and published by Rowman & Littlefield. This book was released on 2019-11-10 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are millions of people who experience issues related to brain health—depression, attention issues, anxiety, forgetfulness, fatigue, and even chronic pain—yet can’t figure out what’s causing their problems and can’t find any relief. They may have seen a myriad of doctors, many of whom do not take their complaints seriously, or worse, turn to the easy, often inappropriate fix of antidepressants or anti-anxiety medications. Traditional medications, supplements, or other therapies haven’t worked. No matter what their age—from children to teens or seniors—people and their loved ones are frustrated, scared, and confused by their continued poor health. Countless others display severe psychiatric symptoms that seem to come out of nowhere, ranging from tics, obsessive-compulsive behaviors and anxiety, to depression, bipolar-like mood swings, and even borderline personality disorder and suicidal ideas. Sometimes, the people affected are the only ones that notices a change to the way they think or feel, and they suffer in silence. Or, they reach out to try to get help, and are all too frequently misdiagnosed. David Younger, a world-renowned physician, provides relief to these patients and their families. His diagnostic techniques and treatment protocols will help readers identify the true cause of their symptoms and put them on a clear path to healing so they no longer feel unbalanced, out of control, forgetful, and exhausted. The Autoimmune Brain connects common brain health symptoms to the changes in the immune system, and particularly bacterial, viral, and parasitic infections. Younger explains his groundbreaking research and adds a new component: how traumatic stress (whether physical or emotional) and genetics affects this same triad as inextricable factors in initiating disease and brain health symptoms. In fact, a change in personality, behavior, coping style, and one’s emotional state may be the first clue that there is a health problem brewing somewhere else in the body. Readers will find new answers to troubling conditions, including: Alzheimer’s disease; Anxiety; Arthritis; Autism; Autonomic disturbances; Bacterial and viral infections; Bipolar Disorder; Cancer; Celiac disease and gluten intolerances; Chronic Fatigue Syndrome (now referred to as Systemic Exertion Intolerance Disease); Chronic Pain; Dementia; Depression; Endocrine Disorders; Immune modulatory therapy using IVIg; Lyme disease and co-infections; Mast cell activation syndrome; Medical cannabis; Obsessive Compulsive Disorder; Orthostatic hypotension; Peripheral Neuropathy; Porphyria; Post-Traumatic Stress Disorder; and Postural orthostatic tachycardia.


Molecular Biology of The Cell

Molecular Biology of The Cell

Author: Bruce Alberts

Publisher:

Published: 2002

Total Pages: 0

ISBN-13: 9780815332183

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: