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Author: Anders Björklund
Publisher: Elsevier Publishing Company
Published: 1985
Total Pages: 746
ISBN-13:
DOWNLOAD EBOOKDownload or read book Neural Grafting in the Mammalian CNS written by Anders Björklund and published by Elsevier Publishing Company. This book was released on 1985 with total page 746 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author: Don M. Gash
Publisher: Elsevier
Published: 1988
Total Pages: 697
ISBN-13: 0444810129
DOWNLOAD EBOOKTransplantation into the Mammalian CNS presents a comprehensive critical overview of recent advances of basic and clinical research in neural transplantation. Special emphasis is devoted to the emerging studies on the use of clinical grafts for the treatment of parkinsonism, the extension of this technology to additional models of neurological deficits, the immunobiology of neural implants, the exploration of trophic factors, and other new directions in the field of transplantation. Due to the extensive list of contents, only content headings are given. Full details can be obtained from the Publisher upon request.
Download or read book Transplantation Into the Mammalian CNS written by Don M. Gash and published by Elsevier. This book was released on 1988 with total page 697 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transplantation into the Mammalian CNS presents a comprehensive critical overview of recent advances of basic and clinical research in neural transplantation. Special emphasis is devoted to the emerging studies on the use of clinical grafts for the treatment of parkinsonism, the extension of this technology to additional models of neurological deficits, the immunobiology of neural implants, the exploration of trophic factors, and other new directions in the field of transplantation. Due to the extensive list of contents, only content headings are given. Full details can be obtained from the Publisher upon request.
Author: William J. Freed
Publisher: MIT Press
Published: 2000
Total Pages: 590
ISBN-13: 9780262062084
DOWNLOAD EBOOKAfter providing basic background on transplantation, brain structure, and development, the book discusses Parkinson's disease, the use of transplants to influence localized brain functions, circuit reconstruction, and genetic engineering and other future technologies.
Download or read book Neural Transplantation written by William J. Freed and published by MIT Press. This book was released on 2000 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: After providing basic background on transplantation, brain structure, and development, the book discusses Parkinson's disease, the use of transplants to influence localized brain functions, circuit reconstruction, and genetic engineering and other future technologies.
Author: John R. Sladek
Publisher:
Published: 2014-01-15
Total Pages: 488
ISBN-13: 9781468446869
DOWNLOAD EBOOKDownload or read book Neural Transplants written by John R. Sladek and published by . This book was released on 2014-01-15 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author: John R. Sladek
Publisher: Springer
Published: 2012-04-06
Total Pages: 454
ISBN-13: 9781468446876
DOWNLOAD EBOOKThe story of mammalian neural transplantation really begins eighty-one years ago. In Chicago in December of 1903, a 34-year-old physician, Elizabeth Hopkins Dunn, working as a research assistant in neurology, initiated a series of experiments to examine the ability of neonatal rat cerebral tissue to survive transplantation into the brain of matched littermates. Out of 46 attempts, four clearly successful grafts were identified. The publication of Dunn's results in 1917, the first credible report to demonstrate the feasibility of mammalian CNS transplants, generated little interest. In fact, the next significant experiment in this field did not appear until 1930. The field continued to grow slowly and quietly as investigators gradually realized the value of neural trans plantation to study problems of development and plasticity in the mammalian nervous system. With the discovery in 1979 that grafted neurons were capable of appropriate and functional interactions with the host brain, interest in neural transplantation esca lated sharply. The extraordinary opportunities created by using functional neural trans plants in investigating basic issues in neurobiology, as well as the clinical implications, excited both scientists and the public. The popularity of neural transplantation has been growing rapidly in the past five years and shows no signs of abating. The present volume was designed to meet two needs created by the rapid growth of this subdiscipline of neurobiology. The first was to provide a thorough review of the experimental foundations of neural transplantation.
Download or read book Neural Transplants written by John R. Sladek and published by Springer. This book was released on 2012-04-06 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: The story of mammalian neural transplantation really begins eighty-one years ago. In Chicago in December of 1903, a 34-year-old physician, Elizabeth Hopkins Dunn, working as a research assistant in neurology, initiated a series of experiments to examine the ability of neonatal rat cerebral tissue to survive transplantation into the brain of matched littermates. Out of 46 attempts, four clearly successful grafts were identified. The publication of Dunn's results in 1917, the first credible report to demonstrate the feasibility of mammalian CNS transplants, generated little interest. In fact, the next significant experiment in this field did not appear until 1930. The field continued to grow slowly and quietly as investigators gradually realized the value of neural trans plantation to study problems of development and plasticity in the mammalian nervous system. With the discovery in 1979 that grafted neurons were capable of appropriate and functional interactions with the host brain, interest in neural transplantation esca lated sharply. The extraordinary opportunities created by using functional neural trans plants in investigating basic issues in neurobiology, as well as the clinical implications, excited both scientists and the public. The popularity of neural transplantation has been growing rapidly in the past five years and shows no signs of abating. The present volume was designed to meet two needs created by the rapid growth of this subdiscipline of neurobiology. The first was to provide a thorough review of the experimental foundations of neural transplantation.
Author: Stephen B. Dunnett
Publisher: Lippincott Williams & Wilkins
Published: 1994
Total Pages: 616
ISBN-13:
DOWNLOAD EBOOKDownload or read book Functional Neural Transplantation written by Stephen B. Dunnett and published by Lippincott Williams & Wilkins. This book was released on 1994 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author: Stephen B. Dunnett
Publisher: Irl Press
Published: 1992
Total Pages: 211
ISBN-13: 9780199632855
DOWNLOAD EBOOKThis is a practical introduction to the techniques of neural transplantation in mammalian brain tissue. It provides a detailed description of the techniques, written by acknowledged experts in the field, with practical details and hints complementing the underlying principles. Each chapter identifies the equipment needed, the preparations to be made in advance, and step-by-step protocols for each procedure. All aspects of neural transplantation surgery are covered, from staging and dissection of embryonic CNS tissues, through the preparation of tissues for implantation, to the transplant surgery itself. A variety of different methods for solid and cell suspension transplantation are covered. Specialized chapters consider genetic engineering of cells, labelling of grafts, and other aspects of tissue manipulation of PNS and gilal tissues; transplantation in neonatal animals, including primates; handling of human embryonic tissues for transplantation; and immunological considerations. The book will be of interest to neuroscientists studying neural development, anatomical plasticity, functional organization, and recovery in the mammalian CNS, and to neurologists and neurosurgeons interested in developing clinical applications of neural transplantation. It should be stressed that these techniques are experimental and not yet for clinical use.
Download or read book Neural Transplantation written by Stephen B. Dunnett and published by Irl Press. This book was released on 1992 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a practical introduction to the techniques of neural transplantation in mammalian brain tissue. It provides a detailed description of the techniques, written by acknowledged experts in the field, with practical details and hints complementing the underlying principles. Each chapter identifies the equipment needed, the preparations to be made in advance, and step-by-step protocols for each procedure. All aspects of neural transplantation surgery are covered, from staging and dissection of embryonic CNS tissues, through the preparation of tissues for implantation, to the transplant surgery itself. A variety of different methods for solid and cell suspension transplantation are covered. Specialized chapters consider genetic engineering of cells, labelling of grafts, and other aspects of tissue manipulation of PNS and gilal tissues; transplantation in neonatal animals, including primates; handling of human embryonic tissues for transplantation; and immunological considerations. The book will be of interest to neuroscientists studying neural development, anatomical plasticity, functional organization, and recovery in the mammalian CNS, and to neurologists and neurosurgeons interested in developing clinical applications of neural transplantation. It should be stressed that these techniques are experimental and not yet for clinical use.
Author: United States. Congress. Office of Technology Assessment
Publisher:
Published: 1990
Total Pages: 206
ISBN-13:
DOWNLOAD EBOOKDownload or read book Neural Grafting written by United States. Congress. Office of Technology Assessment and published by . This book was released on 1990 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author: Dorothy E. Oorschot
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 196
ISBN-13: 3642751083
DOWNLOAD EBOOKThis state-of-the-art review links the experimental data into a cohesive and critical account of CNS regeneration. Research findings are discussed in terms of their relevance to one (or more) of thirteen hypotheses concerned with regeneration in the mammalian CNS. Research findings reviewed include: regeneration in developing mammals and in submammalian vertebrates, the use of transplants and/or pharmacological treatments, in vitro studies on neurotrophic and neurite promoting factors and their potential relevance to CNS regeneration in vivo, and in vitro studies on the types of glial cells that may be responsible for enhancing or suppressing axonal re-growth.
Download or read book Axonal Regeneration in the Mammalian Central Nervous System written by Dorothy E. Oorschot and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This state-of-the-art review links the experimental data into a cohesive and critical account of CNS regeneration. Research findings are discussed in terms of their relevance to one (or more) of thirteen hypotheses concerned with regeneration in the mammalian CNS. Research findings reviewed include: regeneration in developing mammals and in submammalian vertebrates, the use of transplants and/or pharmacological treatments, in vitro studies on neurotrophic and neurite promoting factors and their potential relevance to CNS regeneration in vivo, and in vitro studies on the types of glial cells that may be responsible for enhancing or suppressing axonal re-growth.
Author: R.B. Wallace
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 250
ISBN-13: 1461255392
DOWNLOAD EBOOKDuring the last decade research on neural transplantation in mammals has grown extensively, and has attracted the attention of many young inquisitive scientists. This growth, as the critics point out, has been somewhat random, and has resulted neither in the formulation of basic concepts nor in any other significant achievement. For instance, they question-how is it possible to jump into functional research with clinical bearing when the basic morphological work has not yet been conducted? The criticism, objectively speaking, is valid and is supported by the fact that every investigator who has stepped into this unex plored field of neurosciences has formulated questions in his own way, has followed his own "model" oftransplantation, and has arrived at his own unique conclusions. The potential danger, as the critics emphasize, in this type of approach lies in that instead of evolving into a scientifically solid and valuable field of research, it may end in a confusing and conflicting mass of questionable claims and subjective opinions. The present situation, very likely, is a reflection of unrestrained enthusiasm and imaginativeness of the investigators, and the demands of the times for the so-called "newsworthy" and "breakthrough" publications. Despite these limitations, two important facts have been estab lished in this field. First, as far as transplantation of neural tissues per se is concerned, what was considered impossible by some critics about 10-12 years ago has been shown to be possible.
Download or read book Neural Tissue Transplantation Research written by R.B. Wallace and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last decade research on neural transplantation in mammals has grown extensively, and has attracted the attention of many young inquisitive scientists. This growth, as the critics point out, has been somewhat random, and has resulted neither in the formulation of basic concepts nor in any other significant achievement. For instance, they question-how is it possible to jump into functional research with clinical bearing when the basic morphological work has not yet been conducted? The criticism, objectively speaking, is valid and is supported by the fact that every investigator who has stepped into this unex plored field of neurosciences has formulated questions in his own way, has followed his own "model" oftransplantation, and has arrived at his own unique conclusions. The potential danger, as the critics emphasize, in this type of approach lies in that instead of evolving into a scientifically solid and valuable field of research, it may end in a confusing and conflicting mass of questionable claims and subjective opinions. The present situation, very likely, is a reflection of unrestrained enthusiasm and imaginativeness of the investigators, and the demands of the times for the so-called "newsworthy" and "breakthrough" publications. Despite these limitations, two important facts have been estab lished in this field. First, as far as transplantation of neural tissues per se is concerned, what was considered impossible by some critics about 10-12 years ago has been shown to be possible.
