Neuromodulation Techniques for Pain Treatment

Neuromodulation Techniques for Pain Treatment

Author: Tiago da Silva Freitas

Publisher: Springer Nature

Published: 2021-11-22

Total Pages: 320

ISBN-13: 3030847780

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Neuromodulation implants are currently one of the most successful techniques in the treatment of chronic pain, a condition that affects more and more patients each year, leading to reduced quality of life as well as economic losses. Neuromodulation implants for pain are a relatively new technique and are being increasingly used around the globe. However, technical training is not available for every implanter as there are relatively few centers in the world. Further, refresher courses for low-rate implanters are not available. This book fills that gap by offering an update on the best techniques currently used, providing a step-by-step guide on how to perform these procedures correctly. Based on the experiences of leading physicians in the field, it also discusses how to manage both major and minor complications. Lastly, it covers the neuromodulatory intervention techniques used to treat chronic pain in various clinical areas. As such it is a valuable resource for pain physicians as well as neurosurgeons, orthopedists and anesthetists.


Book Synopsis Neuromodulation Techniques for Pain Treatment by : Tiago da Silva Freitas

Download or read book Neuromodulation Techniques for Pain Treatment written by Tiago da Silva Freitas and published by Springer Nature. This book was released on 2021-11-22 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuromodulation implants are currently one of the most successful techniques in the treatment of chronic pain, a condition that affects more and more patients each year, leading to reduced quality of life as well as economic losses. Neuromodulation implants for pain are a relatively new technique and are being increasingly used around the globe. However, technical training is not available for every implanter as there are relatively few centers in the world. Further, refresher courses for low-rate implanters are not available. This book fills that gap by offering an update on the best techniques currently used, providing a step-by-step guide on how to perform these procedures correctly. Based on the experiences of leading physicians in the field, it also discusses how to manage both major and minor complications. Lastly, it covers the neuromodulatory intervention techniques used to treat chronic pain in various clinical areas. As such it is a valuable resource for pain physicians as well as neurosurgeons, orthopedists and anesthetists.


Neurostimulation for the Treatment of Chronic Pain E-Book

Neurostimulation for the Treatment of Chronic Pain E-Book

Author: Salim Hayek

Publisher: Elsevier Health Sciences

Published: 2011-08-02

Total Pages: 249

ISBN-13: 1455733997

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Neurostimulation for the Treatment of Chronic Pain - a volume in the new Interventional and Neuromodulatory Techniques for Pain Management series - presents state-of-the-art guidance on the full range of neuromodulation techniques performed today. Salim Hayek, MD, PhD and Robert Levy, MD, PhD offer expert advice on a variety of spinal cord, peripheral nerve, and peripheral nerve field stimulation procedures to treat chronic pain. Comprehensive, evidence-based coverage on selecting and performing these techniques - as well as weighing relative risks and complications - helps you ensure optimum outcomes. With access to the fully searchable text at www.expertconsult.com, you’ll have the detailed visual assistance you need right at your fingertips. Understand the rationale and scientific evidence behind interventional and neuromodulatory techniques and master their execution. Optimize outcomes, reduce complications, and minimize risks by adhering to current, evidence-based practice guidelines. Apply the newest developments in motor cortex stimulation, deep brain stimulation, peripheral nerve stimulation, and spinal cord stimulation. Quickly find the information you need in a user-friendly format with strictly templated chapters supplemented with illustrative line drawings, images, and treatment algorithms. Access the fully searchable contents, plus bonus procedural videos, at expertconsult.com.


Book Synopsis Neurostimulation for the Treatment of Chronic Pain E-Book by : Salim Hayek

Download or read book Neurostimulation for the Treatment of Chronic Pain E-Book written by Salim Hayek and published by Elsevier Health Sciences. This book was released on 2011-08-02 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurostimulation for the Treatment of Chronic Pain - a volume in the new Interventional and Neuromodulatory Techniques for Pain Management series - presents state-of-the-art guidance on the full range of neuromodulation techniques performed today. Salim Hayek, MD, PhD and Robert Levy, MD, PhD offer expert advice on a variety of spinal cord, peripheral nerve, and peripheral nerve field stimulation procedures to treat chronic pain. Comprehensive, evidence-based coverage on selecting and performing these techniques - as well as weighing relative risks and complications - helps you ensure optimum outcomes. With access to the fully searchable text at www.expertconsult.com, you’ll have the detailed visual assistance you need right at your fingertips. Understand the rationale and scientific evidence behind interventional and neuromodulatory techniques and master their execution. Optimize outcomes, reduce complications, and minimize risks by adhering to current, evidence-based practice guidelines. Apply the newest developments in motor cortex stimulation, deep brain stimulation, peripheral nerve stimulation, and spinal cord stimulation. Quickly find the information you need in a user-friendly format with strictly templated chapters supplemented with illustrative line drawings, images, and treatment algorithms. Access the fully searchable contents, plus bonus procedural videos, at expertconsult.com.


Neuromodulation Techniques for the Spine

Neuromodulation Techniques for the Spine

Author: Alaa Abd-Elsayed

Publisher: Elsevier Health Sciences

Published: 2023-02-02

Total Pages: 251

ISBN-13: 0323875858

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Neuromodulation Techniques for the Spine, a volume in the Atlas of Interventional Pain Management series, is a concise, practical guide that provides clinicians with detailed, step-by-step guidance on how to perform spinal nerve stimulation procedures for patients with chronic pain. This comprehensive, easy-to-follow guide offers expert coverage of how to deliver safe, accurate, and cost-effective pain relief to patients using all clinically useful imaging modalities, including ultrasound-guided techniques and fluoroscopy. With high-quality images and clear, authoritative guidance throughout, it shows exactly how to evaluate the causes of pain, identify the most promising stimulation technique, locate the site with precision, and deliver effective relief. Offers a comprehensive overview of the latest techniques used in spinal neuromodulation. Features clinically relevant anatomic drawings and radiologic images that provide step-by-step instruction on techniques. Provides clear guidance on the risks and benefits, as well as indications and contraindications, for each procedure. Covers key topics such as Spinal Cord Stimulation (percutaneous and paddle lead placements); Dorsal Root Ganglion; Dorsal Root Ganglion Implants; and Intrathecal Pump (implants, refills). Includes easy-to-follow, templated content on patient selection, preoperative prep, and post-operative care. Contains full-color line drawings, photographs, and ultrasound images that provide you with a firm grasp of the anatomy and equipment involved with each procedure. Highlights potential pitfalls for each technique and offers clinical pearls on how to avoid them.


Book Synopsis Neuromodulation Techniques for the Spine by : Alaa Abd-Elsayed

Download or read book Neuromodulation Techniques for the Spine written by Alaa Abd-Elsayed and published by Elsevier Health Sciences. This book was released on 2023-02-02 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuromodulation Techniques for the Spine, a volume in the Atlas of Interventional Pain Management series, is a concise, practical guide that provides clinicians with detailed, step-by-step guidance on how to perform spinal nerve stimulation procedures for patients with chronic pain. This comprehensive, easy-to-follow guide offers expert coverage of how to deliver safe, accurate, and cost-effective pain relief to patients using all clinically useful imaging modalities, including ultrasound-guided techniques and fluoroscopy. With high-quality images and clear, authoritative guidance throughout, it shows exactly how to evaluate the causes of pain, identify the most promising stimulation technique, locate the site with precision, and deliver effective relief. Offers a comprehensive overview of the latest techniques used in spinal neuromodulation. Features clinically relevant anatomic drawings and radiologic images that provide step-by-step instruction on techniques. Provides clear guidance on the risks and benefits, as well as indications and contraindications, for each procedure. Covers key topics such as Spinal Cord Stimulation (percutaneous and paddle lead placements); Dorsal Root Ganglion; Dorsal Root Ganglion Implants; and Intrathecal Pump (implants, refills). Includes easy-to-follow, templated content on patient selection, preoperative prep, and post-operative care. Contains full-color line drawings, photographs, and ultrasound images that provide you with a firm grasp of the anatomy and equipment involved with each procedure. Highlights potential pitfalls for each technique and offers clinical pearls on how to avoid them.


Neurostimulation for the Treatment of Chronic Pain

Neurostimulation for the Treatment of Chronic Pain

Author: Salim Hayek

Publisher:

Published: 2013

Total Pages: 249

ISBN-13: 9780323223539

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Neurostimulation for the Treatment of Chronic Pain - a volume in the new Interventional and Neuromodulatory Techniques for Pain Management series - presents state-of-the-art guidance on the full range of neuromodulation techniques performed today. Salim Hayek, MD, PhD and Robert Levy, MD, PhD offer expert advice on a variety of spinal cord, peripheral nerve, and peripheral nerve field stimulation procedures to treat chronic pain. Comprehensive, evidence-based coverage on selecting and performing these techniques - as well as weighing relative risks and complications - helps you ensure optimum.


Book Synopsis Neurostimulation for the Treatment of Chronic Pain by : Salim Hayek

Download or read book Neurostimulation for the Treatment of Chronic Pain written by Salim Hayek and published by . This book was released on 2013 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurostimulation for the Treatment of Chronic Pain - a volume in the new Interventional and Neuromodulatory Techniques for Pain Management series - presents state-of-the-art guidance on the full range of neuromodulation techniques performed today. Salim Hayek, MD, PhD and Robert Levy, MD, PhD offer expert advice on a variety of spinal cord, peripheral nerve, and peripheral nerve field stimulation procedures to treat chronic pain. Comprehensive, evidence-based coverage on selecting and performing these techniques - as well as weighing relative risks and complications - helps you ensure optimum.


Interventional and Neuromodulatory Techniques for Pain Management

Interventional and Neuromodulatory Techniques for Pain Management

Author: Timothy R. Deer

Publisher: Saunders

Published: 2012

Total Pages: 0

ISBN-13: 9781437737912

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Annotation Spinal Injections Marc Huntoon, MD; and Samer Nauroze, MD offer expert advice and scientific evidence supporting the use of spinal injections and sympathetic nerve blocks. Comprehensive, evidence-based coverage on selecting and performing these techniques - as well as weighing relative risks and complications - helps you ensure optimum outcomes.


Book Synopsis Interventional and Neuromodulatory Techniques for Pain Management by : Timothy R. Deer

Download or read book Interventional and Neuromodulatory Techniques for Pain Management written by Timothy R. Deer and published by Saunders. This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation Spinal Injections Marc Huntoon, MD; and Samer Nauroze, MD offer expert advice and scientific evidence supporting the use of spinal injections and sympathetic nerve blocks. Comprehensive, evidence-based coverage on selecting and performing these techniques - as well as weighing relative risks and complications - helps you ensure optimum outcomes.


Neurostimulation for the Treatment of Chronic Pain

Neurostimulation for the Treatment of Chronic Pain

Author: Timothy R. Deer

Publisher: Saunders

Published: 2011-09-29

Total Pages: 0

ISBN-13: 9781437722161

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Neurostimulation for the Treatment of Chronic Pain - a volume in the new Interventional and Neuromodulatory Techniques for Pain Management series - presents state-of-the-art guidance on the full range of neuromodulation techniques performed today. Salim Hayek, MD, PhD and Robert Levy, MD, PhD offer expert advice on a variety of spinal cord, peripheral nerve, and peripheral nerve field stimulation procedures to treat chronic pain. Comprehensive, evidence-based coverage on selecting and performing these techniques - as well as weighing relative risks and complications - helps you ensure optimum outcomes. With access to the fully searchable text at www.expertconsult.com, you'll have the detailed visual assistance you need right at your fingertips. Understand the rationale and scientific evidence behind interventional and neuromodulatory techniques and master their execution. Optimize outcomes, reduce complications, and minimize risks by adhering to current, evidence-based practice guidelines. Apply the newest developments in motor cortex stimulation, deep brain stimulation, peripheral nerve stimulation, and spinal cord stimulation. Quickly find the information you need in a user-friendly format with strictly templated chapters supplemented with illustrative line drawings, images, and treatment algorithms. Access the fully searchable contents, plus bonus procedural videos, at expertconsult.com. Improve patient safety and minimize risks with evidence-based, step-by-step guidance for interventional and neuromodulatory techniques


Book Synopsis Neurostimulation for the Treatment of Chronic Pain by : Timothy R. Deer

Download or read book Neurostimulation for the Treatment of Chronic Pain written by Timothy R. Deer and published by Saunders. This book was released on 2011-09-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurostimulation for the Treatment of Chronic Pain - a volume in the new Interventional and Neuromodulatory Techniques for Pain Management series - presents state-of-the-art guidance on the full range of neuromodulation techniques performed today. Salim Hayek, MD, PhD and Robert Levy, MD, PhD offer expert advice on a variety of spinal cord, peripheral nerve, and peripheral nerve field stimulation procedures to treat chronic pain. Comprehensive, evidence-based coverage on selecting and performing these techniques - as well as weighing relative risks and complications - helps you ensure optimum outcomes. With access to the fully searchable text at www.expertconsult.com, you'll have the detailed visual assistance you need right at your fingertips. Understand the rationale and scientific evidence behind interventional and neuromodulatory techniques and master their execution. Optimize outcomes, reduce complications, and minimize risks by adhering to current, evidence-based practice guidelines. Apply the newest developments in motor cortex stimulation, deep brain stimulation, peripheral nerve stimulation, and spinal cord stimulation. Quickly find the information you need in a user-friendly format with strictly templated chapters supplemented with illustrative line drawings, images, and treatment algorithms. Access the fully searchable contents, plus bonus procedural videos, at expertconsult.com. Improve patient safety and minimize risks with evidence-based, step-by-step guidance for interventional and neuromodulatory techniques


Neuromodulation for Facial Pain

Neuromodulation for Facial Pain

Author: K.V. Slavin

Publisher: Karger Medical and Scientific Publishers

Published: 2020-11-16

Total Pages: 209

ISBN-13: 3318067954

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Neuropathic pain involving the face can be very severe and disabling; often, it is hard to control with conventional means and requires use of unconventional interventions on various parts of the trigeminal nociceptive pathways. For the last 60 years, neuromodulation has been used specifically for the treatment of intractable pain in different parts of the human body, including the face and head region. Despite such a long history and existence of many neuromodulation targets, there has not been a dedicated book that would summarize the entire spectrum of neuromodulation approaches that have been – and still are – used for treatment of facial pain. This book begins with dedicated chapters on classification of facial pain and anatomy of facial pain pathways and then dives into specific applications of neuromodulation starting from the periphery all the way to cerebral centers of pain processing, covering both invasive and non-invasive approaches. Written by experts from all over the word, the book offers an up-to-date comprehensive summary of neuromodulation techniques and modalities, providing the readers with a practical guide on clinical details of patient selection, modulation parameters, procedural details, and expected outcomes that may be used in daily clinical practice dealing with most difficult facial pain conditions.


Book Synopsis Neuromodulation for Facial Pain by : K.V. Slavin

Download or read book Neuromodulation for Facial Pain written by K.V. Slavin and published by Karger Medical and Scientific Publishers. This book was released on 2020-11-16 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuropathic pain involving the face can be very severe and disabling; often, it is hard to control with conventional means and requires use of unconventional interventions on various parts of the trigeminal nociceptive pathways. For the last 60 years, neuromodulation has been used specifically for the treatment of intractable pain in different parts of the human body, including the face and head region. Despite such a long history and existence of many neuromodulation targets, there has not been a dedicated book that would summarize the entire spectrum of neuromodulation approaches that have been – and still are – used for treatment of facial pain. This book begins with dedicated chapters on classification of facial pain and anatomy of facial pain pathways and then dives into specific applications of neuromodulation starting from the periphery all the way to cerebral centers of pain processing, covering both invasive and non-invasive approaches. Written by experts from all over the word, the book offers an up-to-date comprehensive summary of neuromodulation techniques and modalities, providing the readers with a practical guide on clinical details of patient selection, modulation parameters, procedural details, and expected outcomes that may be used in daily clinical practice dealing with most difficult facial pain conditions.


Neuromodulation in Headache and Facial Pain Management

Neuromodulation in Headache and Facial Pain Management

Author: Giorgio Lambru

Publisher: Springer Nature

Published: 2019-11-06

Total Pages: 257

ISBN-13: 3030141217

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This book addresses all aspects of neuromodulation therapy in the management of headache and facial pain disorders, paying particular attention to the application of this rapidly growing and fascinating therapy to different forms of headache and facial pain conditions. It is divided into sections covering the principles of and rationale behind neuromodulation for headache, including in-depth discussions of challenging topics such as the definition of refractory headache and prognostic factors, and the technical aspects of devices used to modulate peripheral and central neuronal targets for the management of headaches. In addition, the book reviews the state-of-the art in current neuromodulation practice for headaches, discusses therapeutic strategies and therapy selection for each headache and facial pain disorder, and presents an in-depth, critical analysis of the published evidence, with sections covering innovative devices and emerging applications of novel neuromodulation technologies in the field. Gathering papers by internationally respected, leading experts, the book offers a unique guide to neuromodulation therapies in headache for neurologists, pain specialists, neurosurgeons, neuroscientists, trainees and general practitioners with an interest in headache and facial pain management.


Book Synopsis Neuromodulation in Headache and Facial Pain Management by : Giorgio Lambru

Download or read book Neuromodulation in Headache and Facial Pain Management written by Giorgio Lambru and published by Springer Nature. This book was released on 2019-11-06 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses all aspects of neuromodulation therapy in the management of headache and facial pain disorders, paying particular attention to the application of this rapidly growing and fascinating therapy to different forms of headache and facial pain conditions. It is divided into sections covering the principles of and rationale behind neuromodulation for headache, including in-depth discussions of challenging topics such as the definition of refractory headache and prognostic factors, and the technical aspects of devices used to modulate peripheral and central neuronal targets for the management of headaches. In addition, the book reviews the state-of-the art in current neuromodulation practice for headaches, discusses therapeutic strategies and therapy selection for each headache and facial pain disorder, and presents an in-depth, critical analysis of the published evidence, with sections covering innovative devices and emerging applications of novel neuromodulation technologies in the field. Gathering papers by internationally respected, leading experts, the book offers a unique guide to neuromodulation therapies in headache for neurologists, pain specialists, neurosurgeons, neuroscientists, trainees and general practitioners with an interest in headache and facial pain management.


Neuromodulation

Neuromodulation

Author:

Publisher: Academic Press

Published: 2009-05-05

Total Pages: 1089

ISBN-13: 0080921396

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Neuromodulation will be the first comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. This book provides a complete discussion of the fundamental principles of neuromodulation and therapies applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs. The textbook is highly structured and organized into overarching sections that cover chronic pain, movement disorders, psychiatric disorders, epilepsy, functional electrical stimulation, cardiac, gastrointestinal, genitourinary and organ neuromodulation. The fundamental principles of electricity and infusion, neural tissue interface, biomedical engineering, neuromodulation devices, basic science, neuroanatomy, neurophysiology, imaging and mechanisms are emphasized. In addition to providing details pertaining to the state-of-the-art current practice, innovative and emerging applications are discussed in specific chapters. Finally, the textbook provides specific chapters focusing on the technical aspects of the various neuromodulation procedures as well as technical specifications of various implantable devices. All of the contributors to Neuromodulation represent leading experts in the field. The editors are internationally renowned in their respective fields of neuromodulation, pain management, functional neurosurgery and biomedical engineering. Neuromodulation will be the first and foremost authoritative text on neuromodulation therapies and will establish the gold standard that defines the field for years to come. Key Features The first comprehensive reference on the emerging field of Neuromodulation Editors and authors include all leading figures in the field, and the leaders of the International Neuromodulation Society Over 90 chapters on topics ranging from a layout of the fundamentals (e.g. neuroanatomy, plasticity, bioelectrical effects, infusion therapies), solutions for the biomedical engineering challenges (e.g. materials, how to preserve normal function etc.), to a rundown of the existing applications and their future promise Over 1200 pages in splendid full color, richly illustrated Important areas of application include: control of chronic pain delivery of drugs to the nervous system via implanted devices control of epilepsy, Parkinson, etc. functional restoration, e.g. visual, auditory, restoration after stroke, restoration of motor function after traumatic events stimulation of body organs via neural devices (incl. the heart, abdominal organs, genitourinary organs) overview over newly emerging fields - control of obesity, blood pressure, tinnitus, brain injury, neurodegenerative diseases, brain-machine interfaces


Book Synopsis Neuromodulation by :

Download or read book Neuromodulation written by and published by Academic Press. This book was released on 2009-05-05 with total page 1089 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuromodulation will be the first comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. This book provides a complete discussion of the fundamental principles of neuromodulation and therapies applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs. The textbook is highly structured and organized into overarching sections that cover chronic pain, movement disorders, psychiatric disorders, epilepsy, functional electrical stimulation, cardiac, gastrointestinal, genitourinary and organ neuromodulation. The fundamental principles of electricity and infusion, neural tissue interface, biomedical engineering, neuromodulation devices, basic science, neuroanatomy, neurophysiology, imaging and mechanisms are emphasized. In addition to providing details pertaining to the state-of-the-art current practice, innovative and emerging applications are discussed in specific chapters. Finally, the textbook provides specific chapters focusing on the technical aspects of the various neuromodulation procedures as well as technical specifications of various implantable devices. All of the contributors to Neuromodulation represent leading experts in the field. The editors are internationally renowned in their respective fields of neuromodulation, pain management, functional neurosurgery and biomedical engineering. Neuromodulation will be the first and foremost authoritative text on neuromodulation therapies and will establish the gold standard that defines the field for years to come. Key Features The first comprehensive reference on the emerging field of Neuromodulation Editors and authors include all leading figures in the field, and the leaders of the International Neuromodulation Society Over 90 chapters on topics ranging from a layout of the fundamentals (e.g. neuroanatomy, plasticity, bioelectrical effects, infusion therapies), solutions for the biomedical engineering challenges (e.g. materials, how to preserve normal function etc.), to a rundown of the existing applications and their future promise Over 1200 pages in splendid full color, richly illustrated Important areas of application include: control of chronic pain delivery of drugs to the nervous system via implanted devices control of epilepsy, Parkinson, etc. functional restoration, e.g. visual, auditory, restoration after stroke, restoration of motor function after traumatic events stimulation of body organs via neural devices (incl. the heart, abdominal organs, genitourinary organs) overview over newly emerging fields - control of obesity, blood pressure, tinnitus, brain injury, neurodegenerative diseases, brain-machine interfaces


Textbook of Neuromodulation

Textbook of Neuromodulation

Author: Helena Knotkova

Publisher: Springer

Published: 2014-11-15

Total Pages: 284

ISBN-13: 1493914081

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Until recently, it was thought that the adult brain is modifiable only during early stages of ontogenesis. However, neurophysiological and neuroimaging studies now indicate that the mature human brain is, under certain conditions, capable of substantial neuroplastic changes. Neuroplasticity reflects the ability of the human brain to alter the pattern of neural activation in response to previous experience, and recent findings indicate that the effects of experience can lead to both structural as well as functional reorganization. It has been shown that pathological neuroplastic changes can be reverted/normalized and that the modulation of the neuroplastic changes can be paralleled by improvement of the patient's status. However, there is a gap between the potential of neuromodulation, technical progress and actual preparedness of medical personnel to provide this type of treatment. A prevalent opinion among medical professionals indicates that training programs and educational materials in neuromodulatory techniques are well needed and appreciated. Neuromodulation will focus on the description and discussion of methods currently available for invasive and non-invasive neuromodulation, their clinical potential, significance and practical applications. In order to facilitate understanding of the topic, the initial part of the textbook will review neurophysiological systems involved in neuromodulation and will provide readers with basic principles of neuroplasticity that constitutes the rationale for neuromodulation in human medicine. Additionally, the clinical use of these techniques will be described with special regard to safety and avoidance of complications.


Book Synopsis Textbook of Neuromodulation by : Helena Knotkova

Download or read book Textbook of Neuromodulation written by Helena Knotkova and published by Springer. This book was released on 2014-11-15 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Until recently, it was thought that the adult brain is modifiable only during early stages of ontogenesis. However, neurophysiological and neuroimaging studies now indicate that the mature human brain is, under certain conditions, capable of substantial neuroplastic changes. Neuroplasticity reflects the ability of the human brain to alter the pattern of neural activation in response to previous experience, and recent findings indicate that the effects of experience can lead to both structural as well as functional reorganization. It has been shown that pathological neuroplastic changes can be reverted/normalized and that the modulation of the neuroplastic changes can be paralleled by improvement of the patient's status. However, there is a gap between the potential of neuromodulation, technical progress and actual preparedness of medical personnel to provide this type of treatment. A prevalent opinion among medical professionals indicates that training programs and educational materials in neuromodulatory techniques are well needed and appreciated. Neuromodulation will focus on the description and discussion of methods currently available for invasive and non-invasive neuromodulation, their clinical potential, significance and practical applications. In order to facilitate understanding of the topic, the initial part of the textbook will review neurophysiological systems involved in neuromodulation and will provide readers with basic principles of neuroplasticity that constitutes the rationale for neuromodulation in human medicine. Additionally, the clinical use of these techniques will be described with special regard to safety and avoidance of complications.