Novel Approaches in Treating Major Depressive Disorder (depression)

Novel Approaches in Treating Major Depressive Disorder (depression)

Author: Milena Ćukić Radenković

Publisher:

Published: 2019

Total Pages: 0

ISBN-13: 9781536143829

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Depression is a serious problem. Serious problems often need a complex solution. In her description of novel approaches to treating depression, Dr Radenković is summarising her results from the beginning of her scientific endeavour. As an engineer of electronics with a strong background in theoretical physics, biophysicist and neuroscientist, she aims at filling in the gap between disciplines needed to bring the innovation in the treatment of depression. Starting from the history of electrical and magnetic stimulation important for this field, she is combining the knowledge from biophysics and electromagnetic to explain how both modalities of stimulation can affect our neural tissue. Reviewing the most essential concepts in physiological complexity, she illustrates all the relevant research in different attempts to understand how we can detect the very subtle changes characteristic for a disorder. Those can be recognised from several electrical signals recorded from the body (electrophysiological signals). Fractal and nonlinear measures are in use for several decades, but are still not widely utilized in clinical practice due to deeply rooted obsolete mathematical models originated from the 19th century. Connecting the powerful models from machine learning (data mining) with measures of complexity and irregularity, Dr Radenković demonstrates how their synergy can bring innovative solutions in psychiatry. She tackles crucial questions like "Should scientific research in psychiatry go online?" One of the central questions she is trying to answer is why two modalities of electromagnetic stimulation-rTMS and tDCS- are effective in treatments of depression. A combination of fractal and nonlinear analysis and a well-performed machine learning can become a useful addition to present practice: decision support solution. We can consider it a test which is accessible, easy to use and cost-effective in comparison to many other methodologies tested in contemporary scientific literature. The question is, how long it takes that something scientifically proven translates to clinical practice. Remember how long it took for all doctors to start washing their hands. We can only hope this translation would be faster. Many people need that badly.


Book Synopsis Novel Approaches in Treating Major Depressive Disorder (depression) by : Milena Ćukić Radenković

Download or read book Novel Approaches in Treating Major Depressive Disorder (depression) written by Milena Ćukić Radenković and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Depression is a serious problem. Serious problems often need a complex solution. In her description of novel approaches to treating depression, Dr Radenković is summarising her results from the beginning of her scientific endeavour. As an engineer of electronics with a strong background in theoretical physics, biophysicist and neuroscientist, she aims at filling in the gap between disciplines needed to bring the innovation in the treatment of depression. Starting from the history of electrical and magnetic stimulation important for this field, she is combining the knowledge from biophysics and electromagnetic to explain how both modalities of stimulation can affect our neural tissue. Reviewing the most essential concepts in physiological complexity, she illustrates all the relevant research in different attempts to understand how we can detect the very subtle changes characteristic for a disorder. Those can be recognised from several electrical signals recorded from the body (electrophysiological signals). Fractal and nonlinear measures are in use for several decades, but are still not widely utilized in clinical practice due to deeply rooted obsolete mathematical models originated from the 19th century. Connecting the powerful models from machine learning (data mining) with measures of complexity and irregularity, Dr Radenković demonstrates how their synergy can bring innovative solutions in psychiatry. She tackles crucial questions like "Should scientific research in psychiatry go online?" One of the central questions she is trying to answer is why two modalities of electromagnetic stimulation-rTMS and tDCS- are effective in treatments of depression. A combination of fractal and nonlinear analysis and a well-performed machine learning can become a useful addition to present practice: decision support solution. We can consider it a test which is accessible, easy to use and cost-effective in comparison to many other methodologies tested in contemporary scientific literature. The question is, how long it takes that something scientifically proven translates to clinical practice. Remember how long it took for all doctors to start washing their hands. We can only hope this translation would be faster. Many people need that badly.


Depression

Depression

Author: Madhukar H. Trivedi

Publisher: Oxford University Press

Published: 2019-10-25

Total Pages: 400

ISBN-13: 019092957X

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Major depressive disorder (MDD) is a serious, debilitating, life-shortening illness that affects many persons of all ages and backgrounds. The lifetime risk for MDD is 7-12% for men and 20-25% for women (Kessler et al., 2003). MDD is a disabling disorder that costs the U.S. over $200 billion per year in direct and indirect costs (Greenberg et al., 2015), and is the leading cause of disability worldwide (WHO, 2018). Depression also has detrimental effects on all aspects of social functioning (e.g., self-care, social role, and family life, including household, marital, kinship, and parental roles). While there have been several treatments that are efficacious, many individuals suffering from depression experience life-long challenges due to the chronic and episodic nature of the disease. Identifying strategies to find the right treatments for the right patients is critical. Ongoing research has explored the importance of examining physiologic biomarkers, as well as clinical characteristics to gain a better understanding of subtypes of depression, which will lead to improved treatments and better outcomes. This book provides an introduction to the etiology and pathophysiology of depression, common comorbidities and differential diagnoses, pharmacotherapy strategies, psychotherapeutic and neuromodulation interventions, novel and non-traditional treatment strategies, and considerations in special populations.


Book Synopsis Depression by : Madhukar H. Trivedi

Download or read book Depression written by Madhukar H. Trivedi and published by Oxford University Press. This book was released on 2019-10-25 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Major depressive disorder (MDD) is a serious, debilitating, life-shortening illness that affects many persons of all ages and backgrounds. The lifetime risk for MDD is 7-12% for men and 20-25% for women (Kessler et al., 2003). MDD is a disabling disorder that costs the U.S. over $200 billion per year in direct and indirect costs (Greenberg et al., 2015), and is the leading cause of disability worldwide (WHO, 2018). Depression also has detrimental effects on all aspects of social functioning (e.g., self-care, social role, and family life, including household, marital, kinship, and parental roles). While there have been several treatments that are efficacious, many individuals suffering from depression experience life-long challenges due to the chronic and episodic nature of the disease. Identifying strategies to find the right treatments for the right patients is critical. Ongoing research has explored the importance of examining physiologic biomarkers, as well as clinical characteristics to gain a better understanding of subtypes of depression, which will lead to improved treatments and better outcomes. This book provides an introduction to the etiology and pathophysiology of depression, common comorbidities and differential diagnoses, pharmacotherapy strategies, psychotherapeutic and neuromodulation interventions, novel and non-traditional treatment strategies, and considerations in special populations.


Neurobiology of Depression

Neurobiology of Depression

Author: Joao Luciano de Quevedo

Publisher: Academic Press

Published: 2019-01-03

Total Pages: 471

ISBN-13: 0128133341

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Neurobiology of Depression: Road to Novel Therapeutics synthesizes the basic neurobiology of major depressive disorder with discussions on the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing research perspectives and revolutionizing research into depression. These basic foundational understandings on the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research are combined in this book to aid advanced students and researchers in their understanding of MDD. Depression is one of the most common mental-health disorders caused by a variety of genetic, biological, environmental and psychological factors. Major depressive disorder (MDD) is typically treated with first-line antidepressant agents that primarily target monoamine neurotransmission. However, only approximately one-third of patients with MDD achieve remission following a trial with such an antidepressant. Furthermore, MDD is a heterogeneous phenotype, and new frameworks, such as the NIMH Research Domain Criteria (RDoC) may provide a more accurate, biologically based comprehension of the symptomatic heterogeneity of this devastating illness. Aids readers in understanding major depressive disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments, to antidepressants and novel therapeutics Synthesizes discussions on the cellular and molecular mechanisms underlying symptoms with the clinical aspects of depression


Book Synopsis Neurobiology of Depression by : Joao Luciano de Quevedo

Download or read book Neurobiology of Depression written by Joao Luciano de Quevedo and published by Academic Press. This book was released on 2019-01-03 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiology of Depression: Road to Novel Therapeutics synthesizes the basic neurobiology of major depressive disorder with discussions on the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing research perspectives and revolutionizing research into depression. These basic foundational understandings on the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research are combined in this book to aid advanced students and researchers in their understanding of MDD. Depression is one of the most common mental-health disorders caused by a variety of genetic, biological, environmental and psychological factors. Major depressive disorder (MDD) is typically treated with first-line antidepressant agents that primarily target monoamine neurotransmission. However, only approximately one-third of patients with MDD achieve remission following a trial with such an antidepressant. Furthermore, MDD is a heterogeneous phenotype, and new frameworks, such as the NIMH Research Domain Criteria (RDoC) may provide a more accurate, biologically based comprehension of the symptomatic heterogeneity of this devastating illness. Aids readers in understanding major depressive disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments, to antidepressants and novel therapeutics Synthesizes discussions on the cellular and molecular mechanisms underlying symptoms with the clinical aspects of depression


Handbook of Chronic Depression

Handbook of Chronic Depression

Author: Jonathan Edward Alpert

Publisher: CRC Press

Published: 2014-05-14

Total Pages: 400

ISBN-13: 0824756606

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An in-depth and authoritative framework for clear understanding of the origins, development, and management of chronic depression, this timely reference examines biological, psychosocial, and combined approaches to the treatment of chronic depression-providing strategies to achieve remission, reduce relapse and recurrence, and manage treatment-emergent side-effects in long-term patient care.


Book Synopsis Handbook of Chronic Depression by : Jonathan Edward Alpert

Download or read book Handbook of Chronic Depression written by Jonathan Edward Alpert and published by CRC Press. This book was released on 2014-05-14 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: An in-depth and authoritative framework for clear understanding of the origins, development, and management of chronic depression, this timely reference examines biological, psychosocial, and combined approaches to the treatment of chronic depression-providing strategies to achieve remission, reduce relapse and recurrence, and manage treatment-emergent side-effects in long-term patient care.


Treatment of Depression

Treatment of Depression

Author: Paula J. Clayton

Publisher: Lippincott Williams & Wilkins

Published: 1983

Total Pages: 362

ISBN-13:

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Book Synopsis Treatment of Depression by : Paula J. Clayton

Download or read book Treatment of Depression written by Paula J. Clayton and published by Lippincott Williams & Wilkins. This book was released on 1983 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Major Depressive Disorder

Major Depressive Disorder

Author: Roger S McIntyre

Publisher: Elsevier Health Sciences

Published: 2019-08-25

Total Pages: 202

ISBN-13: 0323581323

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Get a quick, expert overview of the key issues surrounding best practices and current consensus on major depressive disorder (MDD). This concise resource by Drs. Roger S. McIntyre, Carola Rong, Mehala Subramaniapillai, and Yena Lee consolidates today’s available information on this complex topic into one convenient resource, making it an ideal, easy-to-digest reference for both psychiatrists and primary care physicians. Covers genetics and epigenetics, brain structural abnormalities, cognition, neuroendocrine alterations, and inflammatory abnormalities as they relate to MDD. Contains chapters on psychiatric comorbidity, pharmacological treatments, neuromodulatory treatments, lifestyle interventions, internet-based/technology-based interventions, and glutamate alterations.


Book Synopsis Major Depressive Disorder by : Roger S McIntyre

Download or read book Major Depressive Disorder written by Roger S McIntyre and published by Elsevier Health Sciences. This book was released on 2019-08-25 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get a quick, expert overview of the key issues surrounding best practices and current consensus on major depressive disorder (MDD). This concise resource by Drs. Roger S. McIntyre, Carola Rong, Mehala Subramaniapillai, and Yena Lee consolidates today’s available information on this complex topic into one convenient resource, making it an ideal, easy-to-digest reference for both psychiatrists and primary care physicians. Covers genetics and epigenetics, brain structural abnormalities, cognition, neuroendocrine alterations, and inflammatory abnormalities as they relate to MDD. Contains chapters on psychiatric comorbidity, pharmacological treatments, neuromodulatory treatments, lifestyle interventions, internet-based/technology-based interventions, and glutamate alterations.


Novel Approaches to the Neuropharmacology of Mood Disorders

Novel Approaches to the Neuropharmacology of Mood Disorders

Author: Hector J. Carun

Publisher: Frontiers Media SA

Published: 2019-10-24

Total Pages: 111

ISBN-13: 2889630439

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Book Synopsis Novel Approaches to the Neuropharmacology of Mood Disorders by : Hector J. Carun

Download or read book Novel Approaches to the Neuropharmacology of Mood Disorders written by Hector J. Carun and published by Frontiers Media SA. This book was released on 2019-10-24 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt:


The Psychological Treatment of Depression

The Psychological Treatment of Depression

Author: J. Mark G. Williams

Publisher: Psychology Press

Published: 1995

Total Pages: 316

ISBN-13: 9780415128742

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The use of behavioral and cognitive techniques for treating depression has yielded exciting results. Research studies throughout the world have found that Cognitive Behaviour Therapy (CBT) is as effective in the short term as anti-depressant drugs and has longer-lasting effects than medication.The Psychological Treatment of Depressiondescribes the wide range of cognitive behavioral techniques in great detail, enabling practitioners new to CBT to feel confident using them and those already using CBT to update their skills. Since the publication of the first edition in 1984, which sold nearly 20,000 copies, extensive research has continued to be conducted on the outcome of cognitive therapy. In this second edition, the author discusses these recent advances and theories, and provides details of new techniques to use in an in-patient setting. He has also added an introductory chapter for readers who may be less familiar with issues relating to depression. Basic and clear, the textcontains explicit case studies, sample dialogues, checklists, and other helpful aids. The book is a highly effective working manual--a field guide for all mental health practitioners in any discipline who want to incorporate the successful methods of CBT into their work with depressed patients.


Book Synopsis The Psychological Treatment of Depression by : J. Mark G. Williams

Download or read book The Psychological Treatment of Depression written by J. Mark G. Williams and published by Psychology Press. This book was released on 1995 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of behavioral and cognitive techniques for treating depression has yielded exciting results. Research studies throughout the world have found that Cognitive Behaviour Therapy (CBT) is as effective in the short term as anti-depressant drugs and has longer-lasting effects than medication.The Psychological Treatment of Depressiondescribes the wide range of cognitive behavioral techniques in great detail, enabling practitioners new to CBT to feel confident using them and those already using CBT to update their skills. Since the publication of the first edition in 1984, which sold nearly 20,000 copies, extensive research has continued to be conducted on the outcome of cognitive therapy. In this second edition, the author discusses these recent advances and theories, and provides details of new techniques to use in an in-patient setting. He has also added an introductory chapter for readers who may be less familiar with issues relating to depression. Basic and clear, the textcontains explicit case studies, sample dialogues, checklists, and other helpful aids. The book is a highly effective working manual--a field guide for all mental health practitioners in any discipline who want to incorporate the successful methods of CBT into their work with depressed patients.


Translational Research Methods for Major Depressive Disorder

Translational Research Methods for Major Depressive Disorder

Author: Yong-Ku Kim

Publisher: Humana

Published: 2022-02-13

Total Pages: 519

ISBN-13: 9781071620823

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This volume explores the latest techniques used to study brain function and pathophysiology of major depressive disorder (MDD), and includes suggestions of new therapeutic approaches for the treatment of MDD. The chapters into this book are organized into five parts. Part One discusses advanced approaches to studying well-established pathophysiological mechanisms. Part Two details behavioral research methods for MDD. Part Three looks at the cellular and molecular research methods for major depression, and Part Four describes the latest developments in non-invasive neuroimaging. Part Five focuses on the pharmacological and non-pharmacological interactions, including antidepressant agents and their properties, such as sexual side effects and neuroimaging biomarkers. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, Translational Research Methods for Major Depressive Disorders is a valuable resource for researchers and scientists interested in learning more about this important and developing field.


Book Synopsis Translational Research Methods for Major Depressive Disorder by : Yong-Ku Kim

Download or read book Translational Research Methods for Major Depressive Disorder written by Yong-Ku Kim and published by Humana. This book was released on 2022-02-13 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the latest techniques used to study brain function and pathophysiology of major depressive disorder (MDD), and includes suggestions of new therapeutic approaches for the treatment of MDD. The chapters into this book are organized into five parts. Part One discusses advanced approaches to studying well-established pathophysiological mechanisms. Part Two details behavioral research methods for MDD. Part Three looks at the cellular and molecular research methods for major depression, and Part Four describes the latest developments in non-invasive neuroimaging. Part Five focuses on the pharmacological and non-pharmacological interactions, including antidepressant agents and their properties, such as sexual side effects and neuroimaging biomarkers. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, Translational Research Methods for Major Depressive Disorders is a valuable resource for researchers and scientists interested in learning more about this important and developing field.


Depression

Depression

Author: Aaron T. Beck, M.D.

Publisher: University of Pennsylvania Press

Published: 2009-03-25

Total Pages: 436

ISBN-13: 9780812219647

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The second edition of Depression: Causes and Treatment provides a contemporary review of the diagnosis, causes, and treatments of depression. Both biological and psychological treatment approaches are described.


Book Synopsis Depression by : Aaron T. Beck, M.D.

Download or read book Depression written by Aaron T. Beck, M.D. and published by University of Pennsylvania Press. This book was released on 2009-03-25 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Depression: Causes and Treatment provides a contemporary review of the diagnosis, causes, and treatments of depression. Both biological and psychological treatment approaches are described.