Optical Methods for Ultrasensitive Detection and Analysis

Optical Methods for Ultrasensitive Detection and Analysis

Author:

Publisher:

Published: 1991

Total Pages:

ISBN-13:

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Download or read book Optical Methods for Ultrasensitive Detection and Analysis written by and published by . This book was released on 1991 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:


Optical Methods for Ultrasensitive Detection and Analysis

Optical Methods for Ultrasensitive Detection and Analysis

Author: Bryan L. Fearey

Publisher:

Published: 1991

Total Pages: 388

ISBN-13:

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Book Synopsis Optical Methods for Ultrasensitive Detection and Analysis by : Bryan L. Fearey

Download or read book Optical Methods for Ultrasensitive Detection and Analysis written by Bryan L. Fearey and published by . This book was released on 1991 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Advanced Optical Methods for Ultrasensitive Detection

Advanced Optical Methods for Ultrasensitive Detection

Author: Bryan L. Fearey

Publisher:

Published: 1995

Total Pages: 192

ISBN-13:

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Book Synopsis Advanced Optical Methods for Ultrasensitive Detection by : Bryan L. Fearey

Download or read book Advanced Optical Methods for Ultrasensitive Detection written by Bryan L. Fearey and published by . This book was released on 1995 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Advanced Optical Methods for Ultrasensitive Detection

Advanced Optical Methods for Ultrasensitive Detection

Author: Bryan L. Fearey

Publisher:

Published: 1995

Total Pages: 176

ISBN-13:

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Book Synopsis Advanced Optical Methods for Ultrasensitive Detection by : Bryan L. Fearey

Download or read book Advanced Optical Methods for Ultrasensitive Detection written by Bryan L. Fearey and published by . This book was released on 1995 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Lasers

Lasers

Author: Charles Blain

Publisher: Nova Publishers

Published: 2002

Total Pages: 214

ISBN-13: 9781590332252

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Developments in lasers continue to enable progress in many areas such as eye surgery, the recording industry and dozens of others. This book presents citations from the book literature for the last 25 years and groups them for ease of access which is also provided by subject, author and titles indexes.


Book Synopsis Lasers by : Charles Blain

Download or read book Lasers written by Charles Blain and published by Nova Publishers. This book was released on 2002 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developments in lasers continue to enable progress in many areas such as eye surgery, the recording industry and dozens of others. This book presents citations from the book literature for the last 25 years and groups them for ease of access which is also provided by subject, author and titles indexes.


Lyophilized Biologics and Vaccines

Lyophilized Biologics and Vaccines

Author: Dushyant Varshney

Publisher: Springer

Published: 2015-05-19

Total Pages: 399

ISBN-13: 1493923838

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This book provides a detailed account of the most recent developments, challenges and solutions to seamlessly advance and launch a lyophilized biologics or vaccine product, based on diverse modalities, ranging from antibodies (e.g., monoclonal, fused), complex biologics (e.g., antibody drug conjugate, PEGylated proteins), and vaccines (e.g., recombinant-protein based). The authors adeptly guide the reader through all crucial aspects, from biophysical and chemical stability considerations of proteins, analytical methods, advances in controlled ice nucleation and quality-by-design approaches, alternate drying technology, to latest regulatory, packaging and technology transfer considerations to develop a stable, safe and effective therapeutic protein, vaccine and biotechnology products. Lyophilized Biologics and Vaccines: Modality-Based Approaches is composed of four sections with a total of 17 chapters. It serves as a reference to all critical assessments and steps from early pre-formulation stages to product launch: Provides recent understanding of heterogeneity of protein environment and selection of appropriate buffer for stabilization of lyophilized formulations Details the latest developments in instrumental analysis and controlled ice nucleation technology Explains in-depth lyophilized (or dehydrated) formulation strategies considering diverse modalities of biologics and vaccines, including plasmid DNA and lipid-based therapeutics Details an exhaustive update on quality-by-design and process analytical technology approaches, illustrated superbly by case studies and FDA perspective Provides the latest detailed account of alternate drying technologies including spray drying, bulk freeze-drying and crystallization, supported exceptionally by case studies Provides a step-by-step guide through critical considerations during process scale-up, technology transfer, packaging and drug delivery device selection, for a successful lyophilization process validation, regulatory submission and product launch Chapters are written by one or more world-renowned leading authorities from academia, industry or regulatory agencies, whose expertise cover lyophilization of the diverse modalities of biopharmaceuticals. Their contributions are based on the exhaustive review of literature coupled with excellent hands-on experiences in laboratory or GMP setup, making this an exceptional guide to all stages of lyophilized or dehydrated product development.


Book Synopsis Lyophilized Biologics and Vaccines by : Dushyant Varshney

Download or read book Lyophilized Biologics and Vaccines written by Dushyant Varshney and published by Springer. This book was released on 2015-05-19 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a detailed account of the most recent developments, challenges and solutions to seamlessly advance and launch a lyophilized biologics or vaccine product, based on diverse modalities, ranging from antibodies (e.g., monoclonal, fused), complex biologics (e.g., antibody drug conjugate, PEGylated proteins), and vaccines (e.g., recombinant-protein based). The authors adeptly guide the reader through all crucial aspects, from biophysical and chemical stability considerations of proteins, analytical methods, advances in controlled ice nucleation and quality-by-design approaches, alternate drying technology, to latest regulatory, packaging and technology transfer considerations to develop a stable, safe and effective therapeutic protein, vaccine and biotechnology products. Lyophilized Biologics and Vaccines: Modality-Based Approaches is composed of four sections with a total of 17 chapters. It serves as a reference to all critical assessments and steps from early pre-formulation stages to product launch: Provides recent understanding of heterogeneity of protein environment and selection of appropriate buffer for stabilization of lyophilized formulations Details the latest developments in instrumental analysis and controlled ice nucleation technology Explains in-depth lyophilized (or dehydrated) formulation strategies considering diverse modalities of biologics and vaccines, including plasmid DNA and lipid-based therapeutics Details an exhaustive update on quality-by-design and process analytical technology approaches, illustrated superbly by case studies and FDA perspective Provides the latest detailed account of alternate drying technologies including spray drying, bulk freeze-drying and crystallization, supported exceptionally by case studies Provides a step-by-step guide through critical considerations during process scale-up, technology transfer, packaging and drug delivery device selection, for a successful lyophilization process validation, regulatory submission and product launch Chapters are written by one or more world-renowned leading authorities from academia, industry or regulatory agencies, whose expertise cover lyophilization of the diverse modalities of biopharmaceuticals. Their contributions are based on the exhaustive review of literature coupled with excellent hands-on experiences in laboratory or GMP setup, making this an exceptional guide to all stages of lyophilized or dehydrated product development.


The Airborne Microparticle

The Airborne Microparticle

Author: E. James Davis

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 841

ISBN-13: 3642561527

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It has been thirty years since one of the authors (EJD) began a collaboration with Professor Milton Kerker at Clarkson University in Potsdam, New York using light scattering methods to study aerosol processes. The development of a relatively short-lived commercial particle levitator based on a modification of the Millikan oil drop experiment attracted their attention and led the author to the study of single droplets and solid microparticles by levitation methods. The early work on measurements of droplet evaporation rates using light scattering techniques to determine the size slowly expanded and diversified as better instrumentation was developed, and faster computers made it possible to perform Mie theory light scattering calculations with ease. Several milestones can be identified in the progress of single microparticle studies. The first is the introduction of the electrodynamic balance, which provided more robust trapping of a particle. The electrodynamic levitator, which has played an important role in atomic and molecular ion spectroscopy, leading to the Nobel Prize in Physics in 1989 shared by Wolfgang Paul of Bonn University and Hans Dehmelt of the University of Washington, was easily adapted to trap microparticles. Simultaneously, improvements in detectors for acquiring and storing light scattering data and theoretical and experimental studies of the interesting optical properties of microspheres, especially the work on morphology dependent resonances by Arthur Ashkin at the Bell Laboratories, Richard Chang, from Yale University, and Tony Campillo from the Naval Research Laboratories in Washington D. C.


Book Synopsis The Airborne Microparticle by : E. James Davis

Download or read book The Airborne Microparticle written by E. James Davis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 841 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been thirty years since one of the authors (EJD) began a collaboration with Professor Milton Kerker at Clarkson University in Potsdam, New York using light scattering methods to study aerosol processes. The development of a relatively short-lived commercial particle levitator based on a modification of the Millikan oil drop experiment attracted their attention and led the author to the study of single droplets and solid microparticles by levitation methods. The early work on measurements of droplet evaporation rates using light scattering techniques to determine the size slowly expanded and diversified as better instrumentation was developed, and faster computers made it possible to perform Mie theory light scattering calculations with ease. Several milestones can be identified in the progress of single microparticle studies. The first is the introduction of the electrodynamic balance, which provided more robust trapping of a particle. The electrodynamic levitator, which has played an important role in atomic and molecular ion spectroscopy, leading to the Nobel Prize in Physics in 1989 shared by Wolfgang Paul of Bonn University and Hans Dehmelt of the University of Washington, was easily adapted to trap microparticles. Simultaneously, improvements in detectors for acquiring and storing light scattering data and theoretical and experimental studies of the interesting optical properties of microspheres, especially the work on morphology dependent resonances by Arthur Ashkin at the Bell Laboratories, Richard Chang, from Yale University, and Tony Campillo from the Naval Research Laboratories in Washington D. C.


Capillary Electrophoresis in Biotechnology and Environmental Analysis

Capillary Electrophoresis in Biotechnology and Environmental Analysis

Author: Hasan Parvez

Publisher: CRC Press

Published: 2023-01-06

Total Pages: 495

ISBN-13: 1466563699

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This text aims to evaluate the actual impact of high-performance capillary electrophoresis on analytical biotechnology and environmental analysis. The first part of the book presents a survey of present innovations in instrument design and different methods of pre-concentration techniques in order to obtain increased separations at higher sensitivities. The second part contains articles on applications of HPCE to protein and peptide analysis. In the third part, applications of HPCE in the investigation of drug abuse and drug interactions are presented. The last two parts of the book deal with the use of HPCE at low-UV wavelengths and negative-UV absorption. The book should be of interest to those working in HPCE research and applications.


Book Synopsis Capillary Electrophoresis in Biotechnology and Environmental Analysis by : Hasan Parvez

Download or read book Capillary Electrophoresis in Biotechnology and Environmental Analysis written by Hasan Parvez and published by CRC Press. This book was released on 2023-01-06 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text aims to evaluate the actual impact of high-performance capillary electrophoresis on analytical biotechnology and environmental analysis. The first part of the book presents a survey of present innovations in instrument design and different methods of pre-concentration techniques in order to obtain increased separations at higher sensitivities. The second part contains articles on applications of HPCE to protein and peptide analysis. In the third part, applications of HPCE in the investigation of drug abuse and drug interactions are presented. The last two parts of the book deal with the use of HPCE at low-UV wavelengths and negative-UV absorption. The book should be of interest to those working in HPCE research and applications.


Lasers and Current Optical Techniques in Biology

Lasers and Current Optical Techniques in Biology

Author: Giuseppe Palumbo

Publisher: Royal Society of Chemistry

Published: 2007-10-31

Total Pages: 684

ISBN-13: 1847551203

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The introduction of innovative light sources, fibre laser sources and light emitting diodes, is opening unexpected perspectives into optical techniques and is promising new exciting applications in the field of biomedicine. Lasers and Current Optical Techniques in Biology aims to provide an overview of light sources, together with an extensive and authoritative description of the optical techniques in bio-medicine. This book is designed to give biomedical researchers a strong feel for the capability of physical approaches, promote new interdisciplinary interests and persuade more practitioners to take advantage of optical techniques. Current developments in a variety of optical techniques, including Near-Infra Red Spectroscopy, and traditional and advanced fluorescence techniques are covered, ranging from those that are becoming common practice to those that need much more experimentation before they can be accepted as real breakthroughs. Further topics include optical coherence tomography and its variations, polarised light imaging and, principle laser and lamp sources- a usually fragmentary topic, often dispersed among specialist publications. The wide range of topics covered make Lasers and Current Optical Techniques in Biology of interest to a diverse range of scientific communities.


Book Synopsis Lasers and Current Optical Techniques in Biology by : Giuseppe Palumbo

Download or read book Lasers and Current Optical Techniques in Biology written by Giuseppe Palumbo and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: The introduction of innovative light sources, fibre laser sources and light emitting diodes, is opening unexpected perspectives into optical techniques and is promising new exciting applications in the field of biomedicine. Lasers and Current Optical Techniques in Biology aims to provide an overview of light sources, together with an extensive and authoritative description of the optical techniques in bio-medicine. This book is designed to give biomedical researchers a strong feel for the capability of physical approaches, promote new interdisciplinary interests and persuade more practitioners to take advantage of optical techniques. Current developments in a variety of optical techniques, including Near-Infra Red Spectroscopy, and traditional and advanced fluorescence techniques are covered, ranging from those that are becoming common practice to those that need much more experimentation before they can be accepted as real breakthroughs. Further topics include optical coherence tomography and its variations, polarised light imaging and, principle laser and lamp sources- a usually fragmentary topic, often dispersed among specialist publications. The wide range of topics covered make Lasers and Current Optical Techniques in Biology of interest to a diverse range of scientific communities.


Human Genome

Human Genome

Author:

Publisher:

Published: 1992

Total Pages: 264

ISBN-13:

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Book Synopsis Human Genome by :

Download or read book Human Genome written by and published by . This book was released on 1992 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: