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Provides a tutorial on the computational tools that use mathematical optimization concepts and representations for the curation, analysis and redesign of metabolic networks Organizes, for the first time, the fundamentals of mathematical optimization in the context of metabolic network analysis Reviews the fundamentals of different classes of optimization problems including LP, MILP, MLP and MINLP Explains the most efficient ways of formulating a biological problem using mathematical optimization Reviews a variety of relevant problems in metabolic network curation, analysis and redesign with an emphasis on details of optimization formulations Provides a detailed treatment of bilevel optimization techniques for computational strain design and other relevant problems
Book Synopsis Optimization Methods in Metabolic Networks by : Costas D. Maranas
Download or read book Optimization Methods in Metabolic Networks written by Costas D. Maranas and published by John Wiley & Sons. This book was released on 2016-02-23 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a tutorial on the computational tools that use mathematical optimization concepts and representations for the curation, analysis and redesign of metabolic networks Organizes, for the first time, the fundamentals of mathematical optimization in the context of metabolic network analysis Reviews the fundamentals of different classes of optimization problems including LP, MILP, MLP and MINLP Explains the most efficient ways of formulating a biological problem using mathematical optimization Reviews a variety of relevant problems in metabolic network curation, analysis and redesign with an emphasis on details of optimization formulations Provides a detailed treatment of bilevel optimization techniques for computational strain design and other relevant problems
A comprehensive introduction to optimization with a focus on practical algorithms for the design of engineering systems. This book offers a comprehensive introduction to optimization with a focus on practical algorithms. The book approaches optimization from an engineering perspective, where the objective is to design a system that optimizes a set of metrics subject to constraints. Readers will learn about computational approaches for a range of challenges, including searching high-dimensional spaces, handling problems where there are multiple competing objectives, and accommodating uncertainty in the metrics. Figures, examples, and exercises convey the intuition behind the mathematical approaches. The text provides concrete implementations in the Julia programming language. Topics covered include derivatives and their generalization to multiple dimensions; local descent and first- and second-order methods that inform local descent; stochastic methods, which introduce randomness into the optimization process; linear constrained optimization, when both the objective function and the constraints are linear; surrogate models, probabilistic surrogate models, and using probabilistic surrogate models to guide optimization; optimization under uncertainty; uncertainty propagation; expression optimization; and multidisciplinary design optimization. Appendixes offer an introduction to the Julia language, test functions for evaluating algorithm performance, and mathematical concepts used in the derivation and analysis of the optimization methods discussed in the text. The book can be used by advanced undergraduates and graduate students in mathematics, statistics, computer science, any engineering field, (including electrical engineering and aerospace engineering), and operations research, and as a reference for professionals.
Book Synopsis Algorithms for Optimization by : Mykel J. Kochenderfer
Download or read book Algorithms for Optimization written by Mykel J. Kochenderfer and published by MIT Press. This book was released on 2019-03-12 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive introduction to optimization with a focus on practical algorithms for the design of engineering systems. This book offers a comprehensive introduction to optimization with a focus on practical algorithms. The book approaches optimization from an engineering perspective, where the objective is to design a system that optimizes a set of metrics subject to constraints. Readers will learn about computational approaches for a range of challenges, including searching high-dimensional spaces, handling problems where there are multiple competing objectives, and accommodating uncertainty in the metrics. Figures, examples, and exercises convey the intuition behind the mathematical approaches. The text provides concrete implementations in the Julia programming language. Topics covered include derivatives and their generalization to multiple dimensions; local descent and first- and second-order methods that inform local descent; stochastic methods, which introduce randomness into the optimization process; linear constrained optimization, when both the objective function and the constraints are linear; surrogate models, probabilistic surrogate models, and using probabilistic surrogate models to guide optimization; optimization under uncertainty; uncertainty propagation; expression optimization; and multidisciplinary design optimization. Appendixes offer an introduction to the Julia language, test functions for evaluating algorithm performance, and mathematical concepts used in the derivation and analysis of the optimization methods discussed in the text. The book can be used by advanced undergraduates and graduate students in mathematics, statistics, computer science, any engineering field, (including electrical engineering and aerospace engineering), and operations research, and as a reference for professionals.
This book examines optimization problems that in practice involve random model parameters. It details the computation of robust optimal solutions, i.e., optimal solutions that are insensitive with respect to random parameter variations, where appropriate deterministic substitute problems are needed. Based on the probability distribution of the random data and using decision theoretical concepts, optimization problems under stochastic uncertainty are converted into appropriate deterministic substitute problems. Due to the probabilities and expectations involved, the book also shows how to apply approximative solution techniques. Several deterministic and stochastic approximation methods are provided: Taylor expansion methods, regression and response surface methods (RSM), probability inequalities, multiple linearization of survival/failure domains, discretization methods, convex approximation/deterministic descent directions/efficient points, stochastic approximation and gradient procedures and differentiation formulas for probabilities and expectations. In the third edition, this book further develops stochastic optimization methods. In particular, it now shows how to apply stochastic optimization methods to the approximate solution of important concrete problems arising in engineering, economics and operations research.
Book Synopsis Stochastic Optimization Methods by : Kurt Marti
Download or read book Stochastic Optimization Methods written by Kurt Marti and published by Springer. This book was released on 2015-02-21 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines optimization problems that in practice involve random model parameters. It details the computation of robust optimal solutions, i.e., optimal solutions that are insensitive with respect to random parameter variations, where appropriate deterministic substitute problems are needed. Based on the probability distribution of the random data and using decision theoretical concepts, optimization problems under stochastic uncertainty are converted into appropriate deterministic substitute problems. Due to the probabilities and expectations involved, the book also shows how to apply approximative solution techniques. Several deterministic and stochastic approximation methods are provided: Taylor expansion methods, regression and response surface methods (RSM), probability inequalities, multiple linearization of survival/failure domains, discretization methods, convex approximation/deterministic descent directions/efficient points, stochastic approximation and gradient procedures and differentiation formulas for probabilities and expectations. In the third edition, this book further develops stochastic optimization methods. In particular, it now shows how to apply stochastic optimization methods to the approximate solution of important concrete problems arising in engineering, economics and operations research.
The primary goal of this book is to provide a self-contained, comprehensive study of the main ?rst-order methods that are frequently used in solving large-scale problems. First-order methods exploit information on values and gradients/subgradients (but not Hessians) of the functions composing the model under consideration. With the increase in the number of applications that can be modeled as large or even huge-scale optimization problems, there has been a revived interest in using simple methods that require low iteration cost as well as low memory storage. The author has gathered, reorganized, and synthesized (in a unified manner) many results that are currently scattered throughout the literature, many of which cannot be typically found in optimization books. First-Order Methods in Optimization offers comprehensive study of first-order methods with the theoretical foundations; provides plentiful examples and illustrations; emphasizes rates of convergence and complexity analysis of the main first-order methods used to solve large-scale problems; and covers both variables and functional decomposition methods.
Book Synopsis First-Order Methods in Optimization by : Amir Beck
Download or read book First-Order Methods in Optimization written by Amir Beck and published by SIAM. This book was released on 2017-10-02 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: The primary goal of this book is to provide a self-contained, comprehensive study of the main ?rst-order methods that are frequently used in solving large-scale problems. First-order methods exploit information on values and gradients/subgradients (but not Hessians) of the functions composing the model under consideration. With the increase in the number of applications that can be modeled as large or even huge-scale optimization problems, there has been a revived interest in using simple methods that require low iteration cost as well as low memory storage. The author has gathered, reorganized, and synthesized (in a unified manner) many results that are currently scattered throughout the literature, many of which cannot be typically found in optimization books. First-Order Methods in Optimization offers comprehensive study of first-order methods with the theoretical foundations; provides plentiful examples and illustrations; emphasizes rates of convergence and complexity analysis of the main first-order methods used to solve large-scale problems; and covers both variables and functional decomposition methods.
Optimization models play an increasingly important role in financial decisions. This is the first textbook devoted to explaining how recent advances in optimization models, methods and software can be applied to solve problems in computational finance more efficiently and accurately. Chapters discussing the theory and efficient solution methods for all major classes of optimization problems alternate with chapters illustrating their use in modeling problems of mathematical finance. The reader is guided through topics such as volatility estimation, portfolio optimization problems and constructing an index fund, using techniques such as nonlinear optimization models, quadratic programming formulations and integer programming models respectively. The book is based on Master's courses in financial engineering and comes with worked examples, exercises and case studies. It will be welcomed by applied mathematicians, operational researchers and others who work in mathematical and computational finance and who are seeking a text for self-learning or for use with courses.
Book Synopsis Optimization Methods in Finance by : Gerard Cornuejols
Download or read book Optimization Methods in Finance written by Gerard Cornuejols and published by Cambridge University Press. This book was released on 2006-12-21 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optimization models play an increasingly important role in financial decisions. This is the first textbook devoted to explaining how recent advances in optimization models, methods and software can be applied to solve problems in computational finance more efficiently and accurately. Chapters discussing the theory and efficient solution methods for all major classes of optimization problems alternate with chapters illustrating their use in modeling problems of mathematical finance. The reader is guided through topics such as volatility estimation, portfolio optimization problems and constructing an index fund, using techniques such as nonlinear optimization models, quadratic programming formulations and integer programming models respectively. The book is based on Master's courses in financial engineering and comes with worked examples, exercises and case studies. It will be welcomed by applied mathematicians, operational researchers and others who work in mathematical and computational finance and who are seeking a text for self-learning or for use with courses.
Highly readable text elucidates applications of the chain rule of differentiation, integration by parts, parametric curves, line integrals, double integrals, and elementary differential equations. 1974 edition.
Book Synopsis Variational Methods in Optimization by : Donald R. Smith
Download or read book Variational Methods in Optimization written by Donald R. Smith and published by Courier Corporation. This book was released on 1998-01-01 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highly readable text elucidates applications of the chain rule of differentiation, integration by parts, parametric curves, line integrals, double integrals, and elementary differential equations. 1974 edition.
Optimization is an important tool used in decision science and for the analysis of physical systems used in engineering. One can trace its roots to the Calculus of Variations and the work of Euler and Lagrange. This natural and reasonable approach to mathematical programming covers numerical methods for finite-dimensional optimization problems. It begins with very simple ideas progressing through more complicated concepts, concentrating on methods for both unconstrained and constrained optimization.
Book Synopsis Numerical Optimization by : Jorge Nocedal
Download or read book Numerical Optimization written by Jorge Nocedal and published by Springer Science & Business Media. This book was released on 2006-12-11 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optimization is an important tool used in decision science and for the analysis of physical systems used in engineering. One can trace its roots to the Calculus of Variations and the work of Euler and Lagrange. This natural and reasonable approach to mathematical programming covers numerical methods for finite-dimensional optimization problems. It begins with very simple ideas progressing through more complicated concepts, concentrating on methods for both unconstrained and constrained optimization.
Primarily designed as a text for the postgraduate students of mechanical engineering and related branches, it provides an excellent introduction to optimization methods—the overview, the history, and the development. It is equally suitable for the undergraduate students for their electives. The text then moves on to familiarize the students with the formulation of optimization problems, graphical solutions, analytical methods of nonlinear optimization, classical optimization techniques, single variable (one-dimensional) unconstrained optimization, multidimensional problems, constrained optimization, equality and inequality constraints. With complexities of human life, the importance of optimization techniques as a tool has increased manifold. The application of optimization techniques creates an efficient, effective and a better life. Features • Includes numerous illustrations and unsolved problems. • Contains university questions. • Discusses the topics with step-by-step procedures.
Book Synopsis OPTIMIZATION METHODS FOR ENGINEERS by : N.V.S. Raju
Download or read book OPTIMIZATION METHODS FOR ENGINEERS written by N.V.S. Raju and published by PHI Learning Pvt. Ltd.. This book was released on 2014-01-01 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Primarily designed as a text for the postgraduate students of mechanical engineering and related branches, it provides an excellent introduction to optimization methods—the overview, the history, and the development. It is equally suitable for the undergraduate students for their electives. The text then moves on to familiarize the students with the formulation of optimization problems, graphical solutions, analytical methods of nonlinear optimization, classical optimization techniques, single variable (one-dimensional) unconstrained optimization, multidimensional problems, constrained optimization, equality and inequality constraints. With complexities of human life, the importance of optimization techniques as a tool has increased manifold. The application of optimization techniques creates an efficient, effective and a better life. Features • Includes numerous illustrations and unsolved problems. • Contains university questions. • Discusses the topics with step-by-step procedures.
Computational optimization is an important paradigm with a wide range of applications. In virtually all branches of engineering and industry, we almost always try to optimize something - whether to minimize the cost and energy consumption, or to maximize profits, outputs, performance and efficiency. In many cases, this search for optimality is challenging, either because of the high computational cost of evaluating objectives and constraints, or because of the nonlinearity, multimodality, discontinuity and uncertainty of the problem functions in the real-world systems. Another complication is that most problems are often NP-hard, that is, the solution time for finding the optimum increases exponentially with the problem size. The development of efficient algorithms and specialized techniques that address these difficulties is of primary importance for contemporary engineering, science and industry. This book consists of 12 self-contained chapters, contributed from worldwide experts who are working in these exciting areas. The book strives to review and discuss the latest developments concerning optimization and modelling with a focus on methods and algorithms for computational optimization. It also covers well-chosen, real-world applications in science, engineering and industry. Main topics include derivative-free optimization, multi-objective evolutionary algorithms, surrogate-based methods, maximum simulated likelihood estimation, support vector machines, and metaheuristic algorithms. Application case studies include aerodynamic shape optimization, microwave engineering, black-box optimization, classification, economics, inventory optimization and structural optimization. This graduate level book can serve as an excellent reference for lecturers, researchers and students in computational science, engineering and industry.
Book Synopsis Computational Optimization, Methods and Algorithms by : Slawomir Koziel
Download or read book Computational Optimization, Methods and Algorithms written by Slawomir Koziel and published by Springer. This book was released on 2011-06-17 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational optimization is an important paradigm with a wide range of applications. In virtually all branches of engineering and industry, we almost always try to optimize something - whether to minimize the cost and energy consumption, or to maximize profits, outputs, performance and efficiency. In many cases, this search for optimality is challenging, either because of the high computational cost of evaluating objectives and constraints, or because of the nonlinearity, multimodality, discontinuity and uncertainty of the problem functions in the real-world systems. Another complication is that most problems are often NP-hard, that is, the solution time for finding the optimum increases exponentially with the problem size. The development of efficient algorithms and specialized techniques that address these difficulties is of primary importance for contemporary engineering, science and industry. This book consists of 12 self-contained chapters, contributed from worldwide experts who are working in these exciting areas. The book strives to review and discuss the latest developments concerning optimization and modelling with a focus on methods and algorithms for computational optimization. It also covers well-chosen, real-world applications in science, engineering and industry. Main topics include derivative-free optimization, multi-objective evolutionary algorithms, surrogate-based methods, maximum simulated likelihood estimation, support vector machines, and metaheuristic algorithms. Application case studies include aerodynamic shape optimization, microwave engineering, black-box optimization, classification, economics, inventory optimization and structural optimization. This graduate level book can serve as an excellent reference for lecturers, researchers and students in computational science, engineering and industry.