Optimization Methods in Metabolic Networks

Optimization Methods in Metabolic Networks

Author: Costas D. Maranas

Publisher: John Wiley & Sons

Published: 2016-01-05

Total Pages: 288

ISBN-13: 1119189012

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Provides a tutorial on the computational tools that use mathematical optimization concepts and representations for the curation, analysis and redesign of metabolic networks Organizes, for the first time, the fundamentals of mathematical optimization in the context of metabolic network analysis Reviews the fundamentals of different classes of optimization problems including LP, MILP, MLP and MINLP Explains the most efficient ways of formulating a biological problem using mathematical optimization Reviews a variety of relevant problems in metabolic network curation, analysis and redesign with an emphasis on details of optimization formulations Provides a detailed treatment of bilevel optimization techniques for computational strain design and other relevant problems


Book Synopsis Optimization Methods in Metabolic Networks by : Costas D. Maranas

Download or read book Optimization Methods in Metabolic Networks written by Costas D. Maranas and published by John Wiley & Sons. This book was released on 2016-01-05 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a tutorial on the computational tools that use mathematical optimization concepts and representations for the curation, analysis and redesign of metabolic networks Organizes, for the first time, the fundamentals of mathematical optimization in the context of metabolic network analysis Reviews the fundamentals of different classes of optimization problems including LP, MILP, MLP and MINLP Explains the most efficient ways of formulating a biological problem using mathematical optimization Reviews a variety of relevant problems in metabolic network curation, analysis and redesign with an emphasis on details of optimization formulations Provides a detailed treatment of bilevel optimization techniques for computational strain design and other relevant problems


Optimization Methods in Metabolic Networks

Optimization Methods in Metabolic Networks

Author: Costas D. Maranas

Publisher: John Wiley & Sons

Published: 2016-02-23

Total Pages: 278

ISBN-13: 1119028493

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Provides a tutorial on the computational tools that use mathematical optimization concepts and representations for the curation, analysis and redesign of metabolic networks Organizes, for the first time, the fundamentals of mathematical optimization in the context of metabolic network analysis Reviews the fundamentals of different classes of optimization problems including LP, MILP, MLP and MINLP Explains the most efficient ways of formulating a biological problem using mathematical optimization Reviews a variety of relevant problems in metabolic network curation, analysis and redesign with an emphasis on details of optimization formulations Provides a detailed treatment of bilevel optimization techniques for computational strain design and other relevant problems


Book Synopsis Optimization Methods in Metabolic Networks by : Costas D. Maranas

Download or read book Optimization Methods in Metabolic Networks written by Costas D. Maranas and published by John Wiley & Sons. This book was released on 2016-02-23 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a tutorial on the computational tools that use mathematical optimization concepts and representations for the curation, analysis and redesign of metabolic networks Organizes, for the first time, the fundamentals of mathematical optimization in the context of metabolic network analysis Reviews the fundamentals of different classes of optimization problems including LP, MILP, MLP and MINLP Explains the most efficient ways of formulating a biological problem using mathematical optimization Reviews a variety of relevant problems in metabolic network curation, analysis and redesign with an emphasis on details of optimization formulations Provides a detailed treatment of bilevel optimization techniques for computational strain design and other relevant problems


Pathway Analysis and Optimization in Metabolic Engineering

Pathway Analysis and Optimization in Metabolic Engineering

Author: Néstor V. Torres

Publisher: Cambridge University Press

Published: 2002-12-19

Total Pages: 328

ISBN-13: 9781139437615

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Facility in the targeted manipulation of the genetic and metabolic composition of organisms, combined with unprecedented computational power, is forging a niche for a new subspecialty of biotechnology called metabolic engineering. First published in 2002, this book introduces researchers and advanced students in biology and engineering to methods of optimizing biochemical systems of biotechnological relevance. It examines the development of strategies for manipulating metabolic pathways, demonstrates the need for effective systems models, and discusses their design and analysis, while placing special emphasis on optimization. The authors propose power-law models and methods of biochemical systems theory toward these ends. All concepts are derived from first principles, and the text is richly illustrated with numerous graphs and examples throughout. Special features include: nontechnical and technical introductions to models of biochemical systems; a review of basic methods of model design and analysis; concepts of optimization; and detailed case studies.


Book Synopsis Pathway Analysis and Optimization in Metabolic Engineering by : Néstor V. Torres

Download or read book Pathway Analysis and Optimization in Metabolic Engineering written by Néstor V. Torres and published by Cambridge University Press. This book was released on 2002-12-19 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Facility in the targeted manipulation of the genetic and metabolic composition of organisms, combined with unprecedented computational power, is forging a niche for a new subspecialty of biotechnology called metabolic engineering. First published in 2002, this book introduces researchers and advanced students in biology and engineering to methods of optimizing biochemical systems of biotechnological relevance. It examines the development of strategies for manipulating metabolic pathways, demonstrates the need for effective systems models, and discusses their design and analysis, while placing special emphasis on optimization. The authors propose power-law models and methods of biochemical systems theory toward these ends. All concepts are derived from first principles, and the text is richly illustrated with numerous graphs and examples throughout. Special features include: nontechnical and technical introductions to models of biochemical systems; a review of basic methods of model design and analysis; concepts of optimization; and detailed case studies.


A Control-theoretic Approach to Dynamic Optimization of Metabolic Networks

A Control-theoretic Approach to Dynamic Optimization of Metabolic Networks

Author: Diego Antonio Oyarzún Rodríguez

Publisher:

Published: 2010

Total Pages: 0

ISBN-13:

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Book Synopsis A Control-theoretic Approach to Dynamic Optimization of Metabolic Networks by : Diego Antonio Oyarzún Rodríguez

Download or read book A Control-theoretic Approach to Dynamic Optimization of Metabolic Networks written by Diego Antonio Oyarzún Rodríguez and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Systems and Synthetic Metabolic Engineering

Systems and Synthetic Metabolic Engineering

Author: Yanfeng Liu

Publisher: Academic Press

Published: 2020-07-25

Total Pages: 294

ISBN-13: 0128217537

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Systems and Synthetic Metabolic Engineering provides an overview of the development of metabolic engineering within medicine that is fueled by systems and synthetic biology. These newly developed, successful strategies of metabolic engineering guide the audience on how to propose and test proper strategies for metabolic engineering research. In addition to introductory, regulatory and challenges in the field, the book also covers dynamic control and autonomous regulation to control cell metabolism, along with computational modeling and industrial applications. The book is written by leaders in the field, making it ideal for synthetic biologists, researchers, students and anyone working in this area. Discusses the current progress of metabolic engineering, focusing on systems biology and synthetic biology Covers introductory, regulatory, strategies, production and challenges in the field Written technically for synthetic biologists, researchers, students, industrialists, policymakers and stakeholders


Book Synopsis Systems and Synthetic Metabolic Engineering by : Yanfeng Liu

Download or read book Systems and Synthetic Metabolic Engineering written by Yanfeng Liu and published by Academic Press. This book was released on 2020-07-25 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems and Synthetic Metabolic Engineering provides an overview of the development of metabolic engineering within medicine that is fueled by systems and synthetic biology. These newly developed, successful strategies of metabolic engineering guide the audience on how to propose and test proper strategies for metabolic engineering research. In addition to introductory, regulatory and challenges in the field, the book also covers dynamic control and autonomous regulation to control cell metabolism, along with computational modeling and industrial applications. The book is written by leaders in the field, making it ideal for synthetic biologists, researchers, students and anyone working in this area. Discusses the current progress of metabolic engineering, focusing on systems biology and synthetic biology Covers introductory, regulatory, strategies, production and challenges in the field Written technically for synthetic biologists, researchers, students, industrialists, policymakers and stakeholders


Metabolic Network Reconstruction and Modeling

Metabolic Network Reconstruction and Modeling

Author: Marco Fondi

Publisher: Humana Press

Published: 2018-08-30

Total Pages: 410

ISBN-13: 9781493985111

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This volume looks at the latest methodologies used to study cellular metabolism with in silico approaches. The chapters in this book are divided into 3 parts: part I discusses tools and methods used for metabolic reconstructions and basic constraint-based metabolic modeling (CBMM); Part II explores protocols for the generation of experimental data for metabolic reconstruction and modeling, including transcriptomics, proteomics, and mutant generations; and Part III cover advanced techniques for quantitative modeling of cellular metabolism, including dynamic Flux Balance Analysis and multi-objective optimization. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Metabolic Network Reconstruction and Modeling: Methods and Protocols is a valuable resource for qualified investigators studying cellular metabolism, and novice researchers who want to start working with CBMM.


Book Synopsis Metabolic Network Reconstruction and Modeling by : Marco Fondi

Download or read book Metabolic Network Reconstruction and Modeling written by Marco Fondi and published by Humana Press. This book was released on 2018-08-30 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume looks at the latest methodologies used to study cellular metabolism with in silico approaches. The chapters in this book are divided into 3 parts: part I discusses tools and methods used for metabolic reconstructions and basic constraint-based metabolic modeling (CBMM); Part II explores protocols for the generation of experimental data for metabolic reconstruction and modeling, including transcriptomics, proteomics, and mutant generations; and Part III cover advanced techniques for quantitative modeling of cellular metabolism, including dynamic Flux Balance Analysis and multi-objective optimization. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Metabolic Network Reconstruction and Modeling: Methods and Protocols is a valuable resource for qualified investigators studying cellular metabolism, and novice researchers who want to start working with CBMM.


Multi-Omics Technologies for Optimizing Synthetic Biomanufacturing

Multi-Omics Technologies for Optimizing Synthetic Biomanufacturing

Author: Young-Mo Kim

Publisher: Frontiers Media SA

Published: 2022-01-31

Total Pages: 165

ISBN-13: 2889742377

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Book Synopsis Multi-Omics Technologies for Optimizing Synthetic Biomanufacturing by : Young-Mo Kim

Download or read book Multi-Omics Technologies for Optimizing Synthetic Biomanufacturing written by Young-Mo Kim and published by Frontiers Media SA. This book was released on 2022-01-31 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt:


The Metabolic Pathway Engineering Handbook

The Metabolic Pathway Engineering Handbook

Author: Christina Smolke

Publisher: CRC Press

Published: 2009-07-28

Total Pages: 680

ISBN-13: 1439802971

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This first volume of the Metabolic Pathway Engineering Handbook provides an overview of metabolic pathway engineering with a look towards the future. It discusses cellular metabolism, including transport processes inside the cell and energy generating reactions, as well as rare metabolic conversions. This volume also explores balances and reaction


Book Synopsis The Metabolic Pathway Engineering Handbook by : Christina Smolke

Download or read book The Metabolic Pathway Engineering Handbook written by Christina Smolke and published by CRC Press. This book was released on 2009-07-28 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first volume of the Metabolic Pathway Engineering Handbook provides an overview of metabolic pathway engineering with a look towards the future. It discusses cellular metabolism, including transport processes inside the cell and energy generating reactions, as well as rare metabolic conversions. This volume also explores balances and reaction


Microalgae-Based Biofuels and Bioproducts

Microalgae-Based Biofuels and Bioproducts

Author: Raul Muñoz

Publisher: Woodhead Publishing

Published: 2017-06-13

Total Pages: 560

ISBN-13: 0081010273

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Microalgae-Based Biofuels and Bioproducts: From Feedstock Cultivation to End Products compiles contributions from authors from different areas and backgrounds who explore the cultivation and utilization of microalgae biomass for sustainable fuels and chemicals. With a strong focus in emerging industrial and large scale applications, the book summarizes the new achievements in recent years in this field by critically evaluating developments in the field of algal biotechnology, whilst taking into account sustainability issues and techno-economic parameters. It includes information on microalgae cultivation, harvesting, and conversion processes for the production of liquid and gaseous biofuels, such as biogas, bioethanol, biodiesel and biohydrogen. Microalgae biorefinery and biotechnology applications, including for pharmaceuticals, its use as food and feed, and value added bioproducts are also covered. This book’s comprehensive scope makes it an ideal reference for both early stage and consolidated researchers, engineers and graduate students in the algal field, especially in energy, chemical and environmental engineering, biotechnology, biology and agriculture. Presents the most current information on the uses and untapped potential of microalgae in the production of bio-based fuels and chemicals Critically reviews the state-of-the-art feedstock cultivation of biofuels and bioproducts mass production from microalgae, including intermediate stages, such as harvesting and extraction of specific compounds Includes topics in economics and sustainability of large-scale microalgae cultivation and conversion technologies


Book Synopsis Microalgae-Based Biofuels and Bioproducts by : Raul Muñoz

Download or read book Microalgae-Based Biofuels and Bioproducts written by Raul Muñoz and published by Woodhead Publishing. This book was released on 2017-06-13 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microalgae-Based Biofuels and Bioproducts: From Feedstock Cultivation to End Products compiles contributions from authors from different areas and backgrounds who explore the cultivation and utilization of microalgae biomass for sustainable fuels and chemicals. With a strong focus in emerging industrial and large scale applications, the book summarizes the new achievements in recent years in this field by critically evaluating developments in the field of algal biotechnology, whilst taking into account sustainability issues and techno-economic parameters. It includes information on microalgae cultivation, harvesting, and conversion processes for the production of liquid and gaseous biofuels, such as biogas, bioethanol, biodiesel and biohydrogen. Microalgae biorefinery and biotechnology applications, including for pharmaceuticals, its use as food and feed, and value added bioproducts are also covered. This book’s comprehensive scope makes it an ideal reference for both early stage and consolidated researchers, engineers and graduate students in the algal field, especially in energy, chemical and environmental engineering, biotechnology, biology and agriculture. Presents the most current information on the uses and untapped potential of microalgae in the production of bio-based fuels and chemicals Critically reviews the state-of-the-art feedstock cultivation of biofuels and bioproducts mass production from microalgae, including intermediate stages, such as harvesting and extraction of specific compounds Includes topics in economics and sustainability of large-scale microalgae cultivation and conversion technologies


Bioinformatics Research and Development

Bioinformatics Research and Development

Author: Mourad Elloumi

Publisher: Springer Science & Business Media

Published: 2008-08-31

Total Pages: 613

ISBN-13: 3540706003

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This volume contains the papers which were selected for presentation at the second Bio- formatics Research and Development (BIRD) conference held in Vienna, Austria during July 7–9, 2008. BIRD covers a wide range of topics related to bioinformatics. This year sequence analysis and alignment, pathways, networks, systems biology, protein and RNA structure and function, gene expression/regulation and microarrays, databases and data integration, machine learning and data analysis were the subjects of main interest. The decisions of the Program Committee are based on the recommendations of at least three, up to five, reviews for each paper. As a result, 30 of the 61 submitted c- tributions could be accepted for the conference. We were happy to have three invited talks presented by experienced researchers providing visitors with a good overview but also some very important insights into the fascinating domain of bioinformatics. Abstracts and more information on these talks are provided in the conference program as well as at the conference site. In the second part of this volume the selected contributions of the two workshops which were held in parallel to the main conference are presented: Workshop on - namical Aspects of Perturbation, Intervention and Transition in Biological Systems – PETRIN 2008 and Workshop on Algorithms in Molecular Biology – ALBIO 2008 Poster presentations of the BIRD conference are in the companion proceedings published by the Trauner Verlag, Linz.


Book Synopsis Bioinformatics Research and Development by : Mourad Elloumi

Download or read book Bioinformatics Research and Development written by Mourad Elloumi and published by Springer Science & Business Media. This book was released on 2008-08-31 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the papers which were selected for presentation at the second Bio- formatics Research and Development (BIRD) conference held in Vienna, Austria during July 7–9, 2008. BIRD covers a wide range of topics related to bioinformatics. This year sequence analysis and alignment, pathways, networks, systems biology, protein and RNA structure and function, gene expression/regulation and microarrays, databases and data integration, machine learning and data analysis were the subjects of main interest. The decisions of the Program Committee are based on the recommendations of at least three, up to five, reviews for each paper. As a result, 30 of the 61 submitted c- tributions could be accepted for the conference. We were happy to have three invited talks presented by experienced researchers providing visitors with a good overview but also some very important insights into the fascinating domain of bioinformatics. Abstracts and more information on these talks are provided in the conference program as well as at the conference site. In the second part of this volume the selected contributions of the two workshops which were held in parallel to the main conference are presented: Workshop on - namical Aspects of Perturbation, Intervention and Transition in Biological Systems – PETRIN 2008 and Workshop on Algorithms in Molecular Biology – ALBIO 2008 Poster presentations of the BIRD conference are in the companion proceedings published by the Trauner Verlag, Linz.