Pancreatic B Cell Biology in Health and Disease

Pancreatic B Cell Biology in Health and Disease

Author:

Publisher: Academic Press

Published: 2021-04-06

Total Pages: 416

ISBN-13: 0128237562

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Pancreatic B Cell Biology in Health and Disease, Volume 360 presents the latest release in this ongoing series on the novel and widely studied physiology of pancreatic cells in homeostasis and under pathogenic conditions. This new volume includes new chapters on a variety of topics, including Pancreatic Beta Cell Dysfunction in Type 1 Diabetes: The Role of Ifn, Sexual Hormones and Diabetes: The Impact in Pancreatic Beta Cell, Pancreatic Beta Cell Dysfunction in Monogenic Diabetes, The Role of MiRNAs In Beta Cell Function, Pancreatic Beta Cell: How Environmental Endocrine Disruptors Alter Its Function, Enteroviral Infections and Pancreatic Beta Cell Dysfunction, and more. Final sections cover Long Non-Coding Rna-Regulated Pathways in Pancreatic Beta Cell: Their Role in Diabetes and Pancreatic Beta Cell Biology in Health and Disease. Provides updated and extensive review articles that focus on different aspects of pancreatic cell biology Offers a wide range of perspectives for basic and translational research Includes original figures that help readers understand the complex pathways involved in cell function in homeostasis and under pathogenic conditions


Book Synopsis Pancreatic B Cell Biology in Health and Disease by :

Download or read book Pancreatic B Cell Biology in Health and Disease written by and published by Academic Press. This book was released on 2021-04-06 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pancreatic B Cell Biology in Health and Disease, Volume 360 presents the latest release in this ongoing series on the novel and widely studied physiology of pancreatic cells in homeostasis and under pathogenic conditions. This new volume includes new chapters on a variety of topics, including Pancreatic Beta Cell Dysfunction in Type 1 Diabetes: The Role of Ifn, Sexual Hormones and Diabetes: The Impact in Pancreatic Beta Cell, Pancreatic Beta Cell Dysfunction in Monogenic Diabetes, The Role of MiRNAs In Beta Cell Function, Pancreatic Beta Cell: How Environmental Endocrine Disruptors Alter Its Function, Enteroviral Infections and Pancreatic Beta Cell Dysfunction, and more. Final sections cover Long Non-Coding Rna-Regulated Pathways in Pancreatic Beta Cell: Their Role in Diabetes and Pancreatic Beta Cell Biology in Health and Disease. Provides updated and extensive review articles that focus on different aspects of pancreatic cell biology Offers a wide range of perspectives for basic and translational research Includes original figures that help readers understand the complex pathways involved in cell function in homeostasis and under pathogenic conditions

Pancreatic Beta Cell in Health and Disease

Pancreatic Beta Cell in Health and Disease

Author: Susumu Seino

Publisher: Springer Science & Business Media

Published: 2008-04-08

Total Pages: 475

ISBN-13: 4431754520

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The beta cells of the pancreatic islets of Langerhans are the only cells in the body that produce and secrete insulin. This metabolic hormone plays a central role in the maintenance of glucose homeostasis. This book provides a comprehensive review of the beta cell in health and disease. The book’s primary aim is to encourage investigators to become actively involved in diabetes research and the search for new approaches to prevent and treat diabetes.


Book Synopsis Pancreatic Beta Cell in Health and Disease by : Susumu Seino

Download or read book Pancreatic Beta Cell in Health and Disease written by Susumu Seino and published by Springer Science & Business Media. This book was released on 2008-04-08 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: The beta cells of the pancreatic islets of Langerhans are the only cells in the body that produce and secrete insulin. This metabolic hormone plays a central role in the maintenance of glucose homeostasis. This book provides a comprehensive review of the beta cell in health and disease. The book’s primary aim is to encourage investigators to become actively involved in diabetes research and the search for new approaches to prevent and treat diabetes.

Pancreatic Beta Cell in Health and Disease

Pancreatic Beta Cell in Health and Disease

Author: Susumu Seino

Publisher: Springer

Published: 2009-08-29

Total Pages: 476

ISBN-13: 9784431800750

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The beta cells of the pancreatic islets of Langerhans are the only cells in the body that produce and secrete insulin. This metabolic hormone plays a central role in the maintenance of glucose homeostasis. This book provides a comprehensive review of the beta cell in health and disease. The book’s primary aim is to encourage investigators to become actively involved in diabetes research and the search for new approaches to prevent and treat diabetes.


Book Synopsis Pancreatic Beta Cell in Health and Disease by : Susumu Seino

Download or read book Pancreatic Beta Cell in Health and Disease written by Susumu Seino and published by Springer. This book was released on 2009-08-29 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: The beta cells of the pancreatic islets of Langerhans are the only cells in the body that produce and secrete insulin. This metabolic hormone plays a central role in the maintenance of glucose homeostasis. This book provides a comprehensive review of the beta cell in health and disease. The book’s primary aim is to encourage investigators to become actively involved in diabetes research and the search for new approaches to prevent and treat diabetes.

Beta Cells in Health and Disease

Beta Cells in Health and Disease

Author: Shahzad Irfan

Publisher: BoD – Books on Demand

Published: 2024-01-17

Total Pages: 94

ISBN-13: 1837696284

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Beta Cells in Health and Disease presents the latest information on the novel and widely studied physiology of pancreatic cells in homeostasis and under pathogenic conditions. This book includes chapters on a variety of topics, including the importance and the biology of insulin hormone, pancreatic beta cell dysfunction in type 1 diabetes, the biological importance of physical activity in managing type 1 diabetes, the use of stem cell therapy for the treatment of diabetes, the role of microRNAs in modulating beta cell function, and more.


Book Synopsis Beta Cells in Health and Disease by : Shahzad Irfan

Download or read book Beta Cells in Health and Disease written by Shahzad Irfan and published by BoD – Books on Demand. This book was released on 2024-01-17 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: Beta Cells in Health and Disease presents the latest information on the novel and widely studied physiology of pancreatic cells in homeostasis and under pathogenic conditions. This book includes chapters on a variety of topics, including the importance and the biology of insulin hormone, pancreatic beta cell dysfunction in type 1 diabetes, the biological importance of physical activity in managing type 1 diabetes, the use of stem cell therapy for the treatment of diabetes, the role of microRNAs in modulating beta cell function, and more.

The Pancreatic Beta Cell

The Pancreatic Beta Cell

Author:

Publisher: Academic Press

Published: 2014-02-20

Total Pages: 517

ISBN-13: 0128004401

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First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on the pancreatic beta cell. Expertise of the contributors Coverage of a vast array of subjects In depth current information at the molecular to the clinical levels Three-dimensional structures in color Elaborate signaling pathways


Book Synopsis The Pancreatic Beta Cell by :

Download or read book The Pancreatic Beta Cell written by and published by Academic Press. This book was released on 2014-02-20 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on the pancreatic beta cell. Expertise of the contributors Coverage of a vast array of subjects In depth current information at the molecular to the clinical levels Three-dimensional structures in color Elaborate signaling pathways

Pancreatic Islet Biology

Pancreatic Islet Biology

Author: Anandwardhan A. Hardikar

Publisher: Springer

Published: 2016-10-25

Total Pages: 324

ISBN-13: 3319453076

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This comprehensive volume discusses in vitro laboratory development of insulin-producing cells. It encompasses multiple aspects of islet biology—from embryonic development and stem cell differentiation to clinical studies in islet transplantation, regulation of islet beta-cell regeneration, pancreatic progenitors, mathematical modelling of islet development, epigenetic regulation, and much more. The chapter authors represent leading laboratories from around the world who contribute their international perspectives and global expertise. Collectively, they provide the reader with a concise yet detailed knowledge of processes and current developments in islet regenerative biology. Pancreatic Islet Biology, part of the Stem Cell Biology and Regenerative Medicine series, is essential reading for researchers and clinicians in stem cells or endocrinology, especially those focusing on diabetes.


Book Synopsis Pancreatic Islet Biology by : Anandwardhan A. Hardikar

Download or read book Pancreatic Islet Biology written by Anandwardhan A. Hardikar and published by Springer. This book was released on 2016-10-25 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive volume discusses in vitro laboratory development of insulin-producing cells. It encompasses multiple aspects of islet biology—from embryonic development and stem cell differentiation to clinical studies in islet transplantation, regulation of islet beta-cell regeneration, pancreatic progenitors, mathematical modelling of islet development, epigenetic regulation, and much more. The chapter authors represent leading laboratories from around the world who contribute their international perspectives and global expertise. Collectively, they provide the reader with a concise yet detailed knowledge of processes and current developments in islet regenerative biology. Pancreatic Islet Biology, part of the Stem Cell Biology and Regenerative Medicine series, is essential reading for researchers and clinicians in stem cells or endocrinology, especially those focusing on diabetes.

Pancreatic Stem Cells

Pancreatic Stem Cells

Author: Juan Domínguez-Bendala

Publisher: Springer Science & Business Media

Published: 2012-02-10

Total Pages: 157

ISBN-13: 1607611325

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From the discovery of Pdx1, the first “master gene” of pancreatic development, to the most recent findings on the role of microRNAs in beta cell homeostasis, the last fifteen years have seen an unprecedented advance in our understanding of the precise development and organization of the many different cell types that make up the pancreas. It is now widely acknowledged that the therapeutic differentiation of stem cells into pancreatic cells is an ambitious endeavor that will not succeed without a thorough understanding of the molecular processes underlying the native development of the organ. This book, aimed at experts and students alike, offers a comprehensive review of the state of the art in both pancreatic development and regeneration. The many strategies to differentiate adult and embryonic stem cells into pancreatic beta cells are also discussed in the context of potential therapeutic interventions for type I diabetes.


Book Synopsis Pancreatic Stem Cells by : Juan Domínguez-Bendala

Download or read book Pancreatic Stem Cells written by Juan Domínguez-Bendala and published by Springer Science & Business Media. This book was released on 2012-02-10 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the discovery of Pdx1, the first “master gene” of pancreatic development, to the most recent findings on the role of microRNAs in beta cell homeostasis, the last fifteen years have seen an unprecedented advance in our understanding of the precise development and organization of the many different cell types that make up the pancreas. It is now widely acknowledged that the therapeutic differentiation of stem cells into pancreatic cells is an ambitious endeavor that will not succeed without a thorough understanding of the molecular processes underlying the native development of the organ. This book, aimed at experts and students alike, offers a comprehensive review of the state of the art in both pancreatic development and regeneration. The many strategies to differentiate adult and embryonic stem cells into pancreatic beta cells are also discussed in the context of potential therapeutic interventions for type I diabetes.

Cellular Endocrinology in Health and Disease

Cellular Endocrinology in Health and Disease

Author: Alfredo Ulloa-Aguirre

Publisher: Academic Press

Published: 2021-02-02

Total Pages: 488

ISBN-13: 0128198028

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Cellular Endocrinology in Health and Disease, Second Edition, describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work explores and dissects the function of a number of cellular systems. The new edition provides an understanding of how endocrine glands function by integrating information resulting in biological effects on both local and systemic levels, also providing new information on the molecular physiopathogenesis of endocrine neoplasic cells. The new edition expands the most used chapters from the first edition and proposes a series of substitutions and additions to the table of contents. New chapters cover signaling, brown adipose tissue, hypothalamic cell models, cellular basis of insulin resistance, genetics and epigenetics of neuroendocrine tumors, and a series of chapters on endocrine-related cancer. Providing content that crosses disciplines, Cellular Endocrinology in Health and Disease, Second Edition, details how cellular endocrine function contributes to system physiology and mediates endocrine disorders. A methods section proves novel and useful approaches across research focus that will be attractive to medical students, residents, and specialists in the field of endocrinology, as well as to those interested in cellular regulation. Editors Alfredo Ulloa-Aguirre and Ya-Xiong Tao, experts in molecular and cellular aspects of endocrinology, deliver contributions carefully selected for relevance, impact, and clarity of expression from leading field experts Explores endocrine cells biology in normal and pathologic conditions Covers new aspects of endocrine cell function in distinct tissues Provides a view into the biological effect in local and systemic levels 15 new chapters covering the recent developments in the field


Book Synopsis Cellular Endocrinology in Health and Disease by : Alfredo Ulloa-Aguirre

Download or read book Cellular Endocrinology in Health and Disease written by Alfredo Ulloa-Aguirre and published by Academic Press. This book was released on 2021-02-02 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular Endocrinology in Health and Disease, Second Edition, describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work explores and dissects the function of a number of cellular systems. The new edition provides an understanding of how endocrine glands function by integrating information resulting in biological effects on both local and systemic levels, also providing new information on the molecular physiopathogenesis of endocrine neoplasic cells. The new edition expands the most used chapters from the first edition and proposes a series of substitutions and additions to the table of contents. New chapters cover signaling, brown adipose tissue, hypothalamic cell models, cellular basis of insulin resistance, genetics and epigenetics of neuroendocrine tumors, and a series of chapters on endocrine-related cancer. Providing content that crosses disciplines, Cellular Endocrinology in Health and Disease, Second Edition, details how cellular endocrine function contributes to system physiology and mediates endocrine disorders. A methods section proves novel and useful approaches across research focus that will be attractive to medical students, residents, and specialists in the field of endocrinology, as well as to those interested in cellular regulation. Editors Alfredo Ulloa-Aguirre and Ya-Xiong Tao, experts in molecular and cellular aspects of endocrinology, deliver contributions carefully selected for relevance, impact, and clarity of expression from leading field experts Explores endocrine cells biology in normal and pathologic conditions Covers new aspects of endocrine cell function in distinct tissues Provides a view into the biological effect in local and systemic levels 15 new chapters covering the recent developments in the field

Control of Pancreatic Beta Cell Function and Plasticity in Health and Diabetes

Control of Pancreatic Beta Cell Function and Plasticity in Health and Diabetes

Author: David J. Hill

Publisher: Bentham Science Publishers

Published: 2016-12-02

Total Pages: 253

ISBN-13: 1681083655

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Plasticity in insulin-producing cells (β-cells) of the pancreas is a major contributor to metabolic control. Targeted regeneration of pancreatic β-cells for the reversal of diabetes (by optimizing β-cells mass and proliferation to meet metabolic requirements and counter autoimmune response) is still a theoretical intervention. This monograph reviews the biology, ontogeny, capabilities, and present practical limitations of β-cell plasticity. Relevant biochemical pathways are described with the inclusion of information about how they change with aging, during pregnancy, and with diet. Readers will learn the following key aspects about β-cell plasticity: -current knowledge of pancreatic β-cells development, and how β-cell mass and proliferation change throughout the human lifespan -the mechanisms responsible for β-cell plasticity, based on animal models and clinical studies revealing environmental, epigenetic, endocrine and paracrine regulators -the therapeutic potential of resident stem cells within the pancreas / bone marrow and β-cell progenitors This monograph is essential reading for researchers interested in updated knowledge about the molecular and cellular biology of β-cells in the quest to find a reliable therapy for diabetes.


Book Synopsis Control of Pancreatic Beta Cell Function and Plasticity in Health and Diabetes by : David J. Hill

Download or read book Control of Pancreatic Beta Cell Function and Plasticity in Health and Diabetes written by David J. Hill and published by Bentham Science Publishers. This book was released on 2016-12-02 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plasticity in insulin-producing cells (β-cells) of the pancreas is a major contributor to metabolic control. Targeted regeneration of pancreatic β-cells for the reversal of diabetes (by optimizing β-cells mass and proliferation to meet metabolic requirements and counter autoimmune response) is still a theoretical intervention. This monograph reviews the biology, ontogeny, capabilities, and present practical limitations of β-cell plasticity. Relevant biochemical pathways are described with the inclusion of information about how they change with aging, during pregnancy, and with diet. Readers will learn the following key aspects about β-cell plasticity: -current knowledge of pancreatic β-cells development, and how β-cell mass and proliferation change throughout the human lifespan -the mechanisms responsible for β-cell plasticity, based on animal models and clinical studies revealing environmental, epigenetic, endocrine and paracrine regulators -the therapeutic potential of resident stem cells within the pancreas / bone marrow and β-cell progenitors This monograph is essential reading for researchers interested in updated knowledge about the molecular and cellular biology of β-cells in the quest to find a reliable therapy for diabetes.

The Biology of the Pancreatic Cell

The Biology of the Pancreatic Cell

Author: S.L. Howell

Publisher: Elsevier

Published: 1999-04-15

Total Pages: 354

ISBN-13: 9780080877143

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As a result of the key advances made more than 30 years ago, specifically the ability to isolate islets of Langerhans from the pancreas, the ability to measure insulin accurately by immunoasay, and the development of microchemical techniques for studying cells and their components, many research volumes, symposium reports, and original papers have been produced. This explosion of interest has probably had at least three stimuli: 1. the inherent scientific interest in understanding secretion of the pancreatic ß-cell 2. the ß-cells relevance to a very common disease 3. the availability of funding from specific sources related to diabetes research, for instance, Juvenile Diabetes Foundation International and the British Diabetic Association. As a result of all this activity, detailed scientific literature including research reviews are readily available. Surprisingly enough, there are relatively few attempts to summarize this great bulk of knowledge in a way that is accessible to the newcomer to this field and this book is intended to bridge this gap.


Book Synopsis The Biology of the Pancreatic Cell by : S.L. Howell

Download or read book The Biology of the Pancreatic Cell written by S.L. Howell and published by Elsevier. This book was released on 1999-04-15 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a result of the key advances made more than 30 years ago, specifically the ability to isolate islets of Langerhans from the pancreas, the ability to measure insulin accurately by immunoasay, and the development of microchemical techniques for studying cells and their components, many research volumes, symposium reports, and original papers have been produced. This explosion of interest has probably had at least three stimuli: 1. the inherent scientific interest in understanding secretion of the pancreatic ß-cell 2. the ß-cells relevance to a very common disease 3. the availability of funding from specific sources related to diabetes research, for instance, Juvenile Diabetes Foundation International and the British Diabetic Association. As a result of all this activity, detailed scientific literature including research reviews are readily available. Surprisingly enough, there are relatively few attempts to summarize this great bulk of knowledge in a way that is accessible to the newcomer to this field and this book is intended to bridge this gap.