Phosphate Labeling and Sensing in Chemical Biology

Phosphate Labeling and Sensing in Chemical Biology

Author: Henning Jacob Jessen

Publisher: Springer

Published: 2017-07-08

Total Pages: 239

ISBN-13: 3319603574

DOWNLOAD EBOOK

The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.


Book Synopsis Phosphate Labeling and Sensing in Chemical Biology by : Henning Jacob Jessen

Download or read book Phosphate Labeling and Sensing in Chemical Biology written by Henning Jacob Jessen and published by Springer. This book was released on 2017-07-08 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.

Chemical Probes in Biology Science at the Interface of Chemistry, Biology and Medicine

Chemical Probes in Biology Science at the Interface of Chemistry, Biology and Medicine

Author: Manfred P. Schneider

Publisher: Springer Science & Business Media

Published: 2003-11-30

Total Pages: 424

ISBN-13: 9781402017704

DOWNLOAD EBOOK

The field of Bio-organic Chemistry or Chemical Biology, as it it also called, constitutes a highly interdisciplinary branch of chemistry, beyond the traditional pathways in which chemists and biologists have been working in the past. The topics covered in this book include inter alia: anticancer agents, antioxidants, chemotaxis, carbohydrates, DNA detection and delivery, enzyme structure, enzyme assisted syntheses, fluorescent probes, gene therapy, genomics, inositol phospholipids, inositol phosphates, multivalent ligands, organic syntheses, oxidative stress, photoaffinity labeling techniques, natural products - syntheses and biological activities, phospholipases, proteomics, receptors such as tyrosine kinases, signal transduction phenomena, x-ray crystallography and many more. The book represents an excellent survey of the current stete of the art in an exciting area of interdisciplinary science and supplies an incentive for increased cooperation in Science at the Interface of Chemistry, Biology and Medicine.


Book Synopsis Chemical Probes in Biology Science at the Interface of Chemistry, Biology and Medicine by : Manfred P. Schneider

Download or read book Chemical Probes in Biology Science at the Interface of Chemistry, Biology and Medicine written by Manfred P. Schneider and published by Springer Science & Business Media. This book was released on 2003-11-30 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of Bio-organic Chemistry or Chemical Biology, as it it also called, constitutes a highly interdisciplinary branch of chemistry, beyond the traditional pathways in which chemists and biologists have been working in the past. The topics covered in this book include inter alia: anticancer agents, antioxidants, chemotaxis, carbohydrates, DNA detection and delivery, enzyme structure, enzyme assisted syntheses, fluorescent probes, gene therapy, genomics, inositol phospholipids, inositol phosphates, multivalent ligands, organic syntheses, oxidative stress, photoaffinity labeling techniques, natural products - syntheses and biological activities, phospholipases, proteomics, receptors such as tyrosine kinases, signal transduction phenomena, x-ray crystallography and many more. The book represents an excellent survey of the current stete of the art in an exciting area of interdisciplinary science and supplies an incentive for increased cooperation in Science at the Interface of Chemistry, Biology and Medicine.

Biochemistry of Lipids, Lipoproteins and Membranes

Biochemistry of Lipids, Lipoproteins and Membranes

Author: Neale Ridgway

Publisher: Elsevier

Published: 2021-08-19

Total Pages: 738

ISBN-13: 0323983286

DOWNLOAD EBOOK

Biochemistry of Lipids, Lipoproteins and Membranes, Seventh Edition serves as a comprehensive, general reference book for scientists and students studying lipids, lipoproteins and membranes. Here, across 19 chapters, leaders in the field summarize fundamental concepts, recent research developments, data analysis, and implications for human disease and intervention. Topics discussed include lipid biology in both prokaryotes and eukaryotes, fatty acid synthesis, desaturation and elongation, and pathways leading to synthesis of complex phospholipids, sphingolipids and their structural variants. Chapters also examine how bioactive lipids are involved in cell signaling, with an emphasis on disease implications and pathological consequences. As the field advances, each chapter in this new edition has been fully revised to address emerging topics, with all-new coverage of lipid droplets and their role as regulatory organelles for energy homeostasis, as well as their relationship to obesity, liver disease and diabetes. Evolving research in fatty acid handling and storage in eukaryotes is also discussed in-depth, with new sections addressing fatty acid uptake, activation and lipolysis. Fully revised to cover new and emerging topics Provides an important bridge between broad-based biochemistry research and application Presents key concepts that are supported by figures and models to improve understanding Includes references from current literature in each chapter to facilitate in-depth study


Book Synopsis Biochemistry of Lipids, Lipoproteins and Membranes by : Neale Ridgway

Download or read book Biochemistry of Lipids, Lipoproteins and Membranes written by Neale Ridgway and published by Elsevier. This book was released on 2021-08-19 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry of Lipids, Lipoproteins and Membranes, Seventh Edition serves as a comprehensive, general reference book for scientists and students studying lipids, lipoproteins and membranes. Here, across 19 chapters, leaders in the field summarize fundamental concepts, recent research developments, data analysis, and implications for human disease and intervention. Topics discussed include lipid biology in both prokaryotes and eukaryotes, fatty acid synthesis, desaturation and elongation, and pathways leading to synthesis of complex phospholipids, sphingolipids and their structural variants. Chapters also examine how bioactive lipids are involved in cell signaling, with an emphasis on disease implications and pathological consequences. As the field advances, each chapter in this new edition has been fully revised to address emerging topics, with all-new coverage of lipid droplets and their role as regulatory organelles for energy homeostasis, as well as their relationship to obesity, liver disease and diabetes. Evolving research in fatty acid handling and storage in eukaryotes is also discussed in-depth, with new sections addressing fatty acid uptake, activation and lipolysis. Fully revised to cover new and emerging topics Provides an important bridge between broad-based biochemistry research and application Presents key concepts that are supported by figures and models to improve understanding Includes references from current literature in each chapter to facilitate in-depth study

The Chemical Biology of Phosphorus

The Chemical Biology of Phosphorus

Author: Christopher T. Walsh

Publisher: Royal Society of Chemistry

Published: 2020-10-30

Total Pages: 567

ISBN-13: 1839162023

DOWNLOAD EBOOK

Alexander Todd, the 1957 Nobel laureate in chemistry is credited with the statement: "where there is life, there is phosphorus". Phosphorus chemical biology underlies most of life's reactions and processes, from the covalent bonds that hold RNA and DNA together, to the making and spending 75 kg of ATP every day, required to run almost all metabolic and mechanical events in cells. Authored by a renowned biochemist, The Chemical Biology of Phosphorus provides an in-depth, unifying chemical approach to the logic and reactivity of inorganic phosphate and its three major derivatives (anhydrides, mono- and diesters) throughout biology to examine why life depends on phosphorus. Covering the breadth of phosphorus chemistry in biology, this book is ideal for biochemistry students, postgraduates and researchers interested in the chemical logic of phosphate metabolites, energy generation, biopolymer accumulation and phosphoproteomics.


Book Synopsis The Chemical Biology of Phosphorus by : Christopher T. Walsh

Download or read book The Chemical Biology of Phosphorus written by Christopher T. Walsh and published by Royal Society of Chemistry. This book was released on 2020-10-30 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alexander Todd, the 1957 Nobel laureate in chemistry is credited with the statement: "where there is life, there is phosphorus". Phosphorus chemical biology underlies most of life's reactions and processes, from the covalent bonds that hold RNA and DNA together, to the making and spending 75 kg of ATP every day, required to run almost all metabolic and mechanical events in cells. Authored by a renowned biochemist, The Chemical Biology of Phosphorus provides an in-depth, unifying chemical approach to the logic and reactivity of inorganic phosphate and its three major derivatives (anhydrides, mono- and diesters) throughout biology to examine why life depends on phosphorus. Covering the breadth of phosphorus chemistry in biology, this book is ideal for biochemistry students, postgraduates and researchers interested in the chemical logic of phosphate metabolites, energy generation, biopolymer accumulation and phosphoproteomics.

Nonradioactive Labeling and Detection of Biomolecules

Nonradioactive Labeling and Detection of Biomolecules

Author: Christoph Kessler

Publisher: Springer

Published: 2012-12-06

Total Pages: 449

ISBN-13: 3662001446

DOWNLOAD EBOOK

All the bioanalytical labeling and detection techniques in one source! This book gathers together all the important nonradioactive labeling techniques for nucleic acids, proteins, glycoproteins and glycolipids like Digoxigenin:Anti-Dioxigenin (DIG), Biotin, 5-Bromodeoxyuridine (BrdU), Sulfone, Immunogold, Silver Enhancement, and Synthetic Nucleic Acid Probe (SNAP) as well as the standard procedures for optical, chemical, biological, electrochemiluminescent and fluorescent detection. Additionally, applications for the use of non-isotopically labeled biomolecules are described. Specific protocols are given for hybridization analysis such as blot, colony/plaque and in-situ hybridization formats, quantitative formats, and also nonradioactivetechniques for nucleic acid sequencing and amplification. Each chapter contains a short introduction, a detailed description of the method with labprotocols, troubleshooting tips and references.


Book Synopsis Nonradioactive Labeling and Detection of Biomolecules by : Christoph Kessler

Download or read book Nonradioactive Labeling and Detection of Biomolecules written by Christoph Kessler and published by Springer. This book was released on 2012-12-06 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: All the bioanalytical labeling and detection techniques in one source! This book gathers together all the important nonradioactive labeling techniques for nucleic acids, proteins, glycoproteins and glycolipids like Digoxigenin:Anti-Dioxigenin (DIG), Biotin, 5-Bromodeoxyuridine (BrdU), Sulfone, Immunogold, Silver Enhancement, and Synthetic Nucleic Acid Probe (SNAP) as well as the standard procedures for optical, chemical, biological, electrochemiluminescent and fluorescent detection. Additionally, applications for the use of non-isotopically labeled biomolecules are described. Specific protocols are given for hybridization analysis such as blot, colony/plaque and in-situ hybridization formats, quantitative formats, and also nonradioactivetechniques for nucleic acid sequencing and amplification. Each chapter contains a short introduction, a detailed description of the method with labprotocols, troubleshooting tips and references.

Chemical and Biological Sensors 11 -and- MEMS/NEMS 11

Chemical and Biological Sensors 11 -and- MEMS/NEMS 11

Author: Z. Aguilar

Publisher: The Electrochemical Society

Published: 2014

Total Pages: 262

ISBN-13: 160768537X

DOWNLOAD EBOOK


Book Synopsis Chemical and Biological Sensors 11 -and- MEMS/NEMS 11 by : Z. Aguilar

Download or read book Chemical and Biological Sensors 11 -and- MEMS/NEMS 11 written by Z. Aguilar and published by The Electrochemical Society. This book was released on 2014 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chemical Biology of Glycoproteins

Chemical Biology of Glycoproteins

Author: Zhongping Tan

Publisher: Royal Society of Chemistry

Published: 2017-03-20

Total Pages: 421

ISBN-13: 1788011228

DOWNLOAD EBOOK

Glycans play a vital role in modulating protein structure and function from involvement in protein folding, solubility and stability to regulation of tissue distribution, recognition specificity, and biological activity. They can act as both positive and negative regulators of protein function, providing an additional level of control with respect to genetic and environmental conditions. Due to the complexity of glycosylated protein forms, elucidating structural and functional information has been challenging task for researchers but recent development of chemical biology-based tools and techniques is bridging these knowledge gaps. This book provides a thorough review of the current state of glycoprotein chemical biology, describing the development and application of glycoprotein and glycan synthesis technologies for understanding and manipulating protein glycosylation.


Book Synopsis Chemical Biology of Glycoproteins by : Zhongping Tan

Download or read book Chemical Biology of Glycoproteins written by Zhongping Tan and published by Royal Society of Chemistry. This book was released on 2017-03-20 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glycans play a vital role in modulating protein structure and function from involvement in protein folding, solubility and stability to regulation of tissue distribution, recognition specificity, and biological activity. They can act as both positive and negative regulators of protein function, providing an additional level of control with respect to genetic and environmental conditions. Due to the complexity of glycosylated protein forms, elucidating structural and functional information has been challenging task for researchers but recent development of chemical biology-based tools and techniques is bridging these knowledge gaps. This book provides a thorough review of the current state of glycoprotein chemical biology, describing the development and application of glycoprotein and glycan synthesis technologies for understanding and manipulating protein glycosylation.

Non-Radioactive Labelling

Non-Radioactive Labelling

Author: A. J. Garman

Publisher: Elsevier

Published: 1997-03-20

Total Pages: 155

ISBN-13: 0080551092

DOWNLOAD EBOOK

Biological Techniques is a series of volumes aimed at introducing to a wide audience the latest advances in methodology. The pitfalls and problems of new techniques are given due consideration, as are those small but vital details not always explicit in the methods sections of journal papers.In recent years, most biological laboratories have been invaded by computers and a wealth of new DNA technology and this will be reflected in many of the titles appearing in the series.The books will be of value to advanced researchers and graduate students seeking to learn and apply new techniques, and will be useful to teachers of advanced undergraduate courses involving practical or project work.Labelled biomolecules are an essential tool in life science research, and non-radioactive labels are becoming increasingly important due to their convenience of measurement, greater safety and lack of disposal problems compared to radioactive labels.This book provides practical information, background theory and protocols to allow a beginner to label many types of biomolecules, including proteins, peptides, nucleic acids and small molecules.This book is essential for biochemists, molecular biologists and cell biologists wanting to use non-radioactively labelled molecules. Aimed at researchers without specific expertise in chemistry, the book includes: A review of the main signal systems and labels available, indicating their strengths and weaknesses Discussion of the most useful strategies for labelling the various biomolecules 32 protocols covering common labelling needs Descriptions of the factors governing protocol design, enabling protocols to be modified for different applications Sources of information including references, data and suppliers


Book Synopsis Non-Radioactive Labelling by : A. J. Garman

Download or read book Non-Radioactive Labelling written by A. J. Garman and published by Elsevier. This book was released on 1997-03-20 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Techniques is a series of volumes aimed at introducing to a wide audience the latest advances in methodology. The pitfalls and problems of new techniques are given due consideration, as are those small but vital details not always explicit in the methods sections of journal papers.In recent years, most biological laboratories have been invaded by computers and a wealth of new DNA technology and this will be reflected in many of the titles appearing in the series.The books will be of value to advanced researchers and graduate students seeking to learn and apply new techniques, and will be useful to teachers of advanced undergraduate courses involving practical or project work.Labelled biomolecules are an essential tool in life science research, and non-radioactive labels are becoming increasingly important due to their convenience of measurement, greater safety and lack of disposal problems compared to radioactive labels.This book provides practical information, background theory and protocols to allow a beginner to label many types of biomolecules, including proteins, peptides, nucleic acids and small molecules.This book is essential for biochemists, molecular biologists and cell biologists wanting to use non-radioactively labelled molecules. Aimed at researchers without specific expertise in chemistry, the book includes: A review of the main signal systems and labels available, indicating their strengths and weaknesses Discussion of the most useful strategies for labelling the various biomolecules 32 protocols covering common labelling needs Descriptions of the factors governing protocol design, enabling protocols to be modified for different applications Sources of information including references, data and suppliers

Challenges and Innovations in Ocean In Situ Sensors

Challenges and Innovations in Ocean In Situ Sensors

Author: Eric Delory

Publisher: Elsevier

Published: 2018-09-21

Total Pages: 408

ISBN-13: 0128098872

DOWNLOAD EBOOK

Challenges and Innovations in Ocean In-Situ Sensors: Measuring Inner Ocean Processes and Health in the Digital Age highlights collaborations of industry and academia in identifying the key challenges and solutions related to ocean observations. A new generation of sensors is presented that addresses the need for higher reliability (e.g. against biofouling), better integration on platforms in terms of size and communication, and data flow across domains (in-situ, space, etc.). Several developments are showcased using a broad diversity of measuring techniques and technologies. Chapters address different sensors and approaches for measurements, including applications, quality monitoring and initiatives that will guide the need for monitoring. Integrates information across key marine and maritime sectors and supports regional policy requirements on monitoring programs Offers tactics for enabling early detection and more effective monitoring of the marine environment and implementation of appropriate management actions Presents new technologies driving the next generation of sensors, allowing readers to understand new capabilities for monitoring and opportunities for another generation of sensors Includes a global vision for ocean monitoring that fosters a new perspective on the direction of ocean measurements


Book Synopsis Challenges and Innovations in Ocean In Situ Sensors by : Eric Delory

Download or read book Challenges and Innovations in Ocean In Situ Sensors written by Eric Delory and published by Elsevier. This book was released on 2018-09-21 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Challenges and Innovations in Ocean In-Situ Sensors: Measuring Inner Ocean Processes and Health in the Digital Age highlights collaborations of industry and academia in identifying the key challenges and solutions related to ocean observations. A new generation of sensors is presented that addresses the need for higher reliability (e.g. against biofouling), better integration on platforms in terms of size and communication, and data flow across domains (in-situ, space, etc.). Several developments are showcased using a broad diversity of measuring techniques and technologies. Chapters address different sensors and approaches for measurements, including applications, quality monitoring and initiatives that will guide the need for monitoring. Integrates information across key marine and maritime sectors and supports regional policy requirements on monitoring programs Offers tactics for enabling early detection and more effective monitoring of the marine environment and implementation of appropriate management actions Presents new technologies driving the next generation of sensors, allowing readers to understand new capabilities for monitoring and opportunities for another generation of sensors Includes a global vision for ocean monitoring that fosters a new perspective on the direction of ocean measurements

New Methods and Sensors for Membrane and Cell Volume Research

New Methods and Sensors for Membrane and Cell Volume Research

Author:

Publisher: Academic Press

Published: 2021-12-01

Total Pages: 428

ISBN-13: 0323911153

DOWNLOAD EBOOK

New Methods and Sensors for Membrane and Cell Volume Research, Volume 88 provides an overview of novel experimental approaches to study both the cell membrane and the under-membrane space – the cytosol, which have lately began drawing renewed attention. The book's overall emphasis is on fluorescent and FRET-based sensors, however, other optical (such as variants of transmission microscopy) and non-optical methods (neutron scattering and mass spectrometry) also have dedicated chapters. This volume provides a rare review of experimental approaches to study intracellular phase transitions, as well as anion channels, membrane tension and dynamics, and other topics of intense current interest. Describes novel FRET-based membrane sensors Reviews selected non-optical approaches to membrane structure and dynamics Describes traditional and modern aspects of cell volume research, such as phase transitions and macromolecular crowding


Book Synopsis New Methods and Sensors for Membrane and Cell Volume Research by :

Download or read book New Methods and Sensors for Membrane and Cell Volume Research written by and published by Academic Press. This book was released on 2021-12-01 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Methods and Sensors for Membrane and Cell Volume Research, Volume 88 provides an overview of novel experimental approaches to study both the cell membrane and the under-membrane space – the cytosol, which have lately began drawing renewed attention. The book's overall emphasis is on fluorescent and FRET-based sensors, however, other optical (such as variants of transmission microscopy) and non-optical methods (neutron scattering and mass spectrometry) also have dedicated chapters. This volume provides a rare review of experimental approaches to study intracellular phase transitions, as well as anion channels, membrane tension and dynamics, and other topics of intense current interest. Describes novel FRET-based membrane sensors Reviews selected non-optical approaches to membrane structure and dynamics Describes traditional and modern aspects of cell volume research, such as phase transitions and macromolecular crowding