Platelets, Haemostasis and Inflammation

Platelets, Haemostasis and Inflammation

Author: Andreas Zirlik

Publisher: Springer

Published: 2017-12-21

Total Pages: 295

ISBN-13: 3319662244

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The book depicts the various roles of platelets in a variety of cardio-metabolic diseases. Traditional and non-traditional platelet functions are described in detail in atherosclerosis, metabolic syndrome, diabetes, myocardial infarction, and other vascular pathologies. Particular focus is put on platelets as a link between haemostasis and inflammation contributing to both. Last but not least the books links the most recent advances in basic sciences with promising novel therapeutic applications and first results of clinical trials. The book is written for biomedical scientists in the sub disciplines vascular biology, biochemistry and immunology; and it as well will be of interest and value for academic physicians like cardiologists, hematologists, general internists and vascular surgeons.


Book Synopsis Platelets, Haemostasis and Inflammation by : Andreas Zirlik

Download or read book Platelets, Haemostasis and Inflammation written by Andreas Zirlik and published by Springer. This book was released on 2017-12-21 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book depicts the various roles of platelets in a variety of cardio-metabolic diseases. Traditional and non-traditional platelet functions are described in detail in atherosclerosis, metabolic syndrome, diabetes, myocardial infarction, and other vascular pathologies. Particular focus is put on platelets as a link between haemostasis and inflammation contributing to both. Last but not least the books links the most recent advances in basic sciences with promising novel therapeutic applications and first results of clinical trials. The book is written for biomedical scientists in the sub disciplines vascular biology, biochemistry and immunology; and it as well will be of interest and value for academic physicians like cardiologists, hematologists, general internists and vascular surgeons.

Mechanisms of Vascular Disease

Mechanisms of Vascular Disease

Author: Robert Fitridge

Publisher: University of Adelaide Press

Published: 2011

Total Pages: 589

ISBN-13: 1922064009

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New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.


Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Platelets and Immune Responses During Thromboinflammation

Platelets and Immune Responses During Thromboinflammation

Author: Mirta Schattner

Publisher: Frontiers Media SA

Published: 2020-07-09

Total Pages: 196

ISBN-13: 2889638391

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Book Synopsis Platelets and Immune Responses During Thromboinflammation by : Mirta Schattner

Download or read book Platelets and Immune Responses During Thromboinflammation written by Mirta Schattner and published by Frontiers Media SA. This book was released on 2020-07-09 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Platelet-Vessel Wall Interactions in Hemostasis and Thrombosis

Platelet-Vessel Wall Interactions in Hemostasis and Thrombosis

Author: Rolando E. Rumbaut

Publisher: Biota Publishing

Published: 2010-02-01

Total Pages: 77

ISBN-13: 1615040404

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Platelets are essential mediators of the physiologic process of hemostasis and pathologic thrombosis. While platelets do not interact with vascular walls under normal conditions, vascular injury or inflammation result in a coordinated series of events including platelet adhesion, aggregation, and promotion of coagulation. In this review, we describe the primary mechanisms involved in these responses in various vascular beds of both macro- and microvessels, and outline key unresolved aspects of these important interactions.


Book Synopsis Platelet-Vessel Wall Interactions in Hemostasis and Thrombosis by : Rolando E. Rumbaut

Download or read book Platelet-Vessel Wall Interactions in Hemostasis and Thrombosis written by Rolando E. Rumbaut and published by Biota Publishing. This book was released on 2010-02-01 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelets are essential mediators of the physiologic process of hemostasis and pathologic thrombosis. While platelets do not interact with vascular walls under normal conditions, vascular injury or inflammation result in a coordinated series of events including platelet adhesion, aggregation, and promotion of coagulation. In this review, we describe the primary mechanisms involved in these responses in various vascular beds of both macro- and microvessels, and outline key unresolved aspects of these important interactions.

Platelets in Thrombotic and Non-Thrombotic Disorders

Platelets in Thrombotic and Non-Thrombotic Disorders

Author: Paolo Gresele

Publisher: Springer

Published: 2017-03-08

Total Pages: 1445

ISBN-13: 3319474626

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This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis.


Book Synopsis Platelets in Thrombotic and Non-Thrombotic Disorders by : Paolo Gresele

Download or read book Platelets in Thrombotic and Non-Thrombotic Disorders written by Paolo Gresele and published by Springer. This book was released on 2017-03-08 with total page 1445 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis.

Established and Novel Roles of Platelets in Health and Disease

Established and Novel Roles of Platelets in Health and Disease

Author: Marie Lordkipanidzé

Publisher: Frontiers Media SA

Published: 2022-03-02

Total Pages: 226

ISBN-13: 288974552X

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Book Synopsis Established and Novel Roles of Platelets in Health and Disease by : Marie Lordkipanidzé

Download or read book Established and Novel Roles of Platelets in Health and Disease written by Marie Lordkipanidzé and published by Frontiers Media SA. This book was released on 2022-03-02 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Non-Thrombotic Role of Platelets in Health and Disease

The Non-Thrombotic Role of Platelets in Health and Disease

Author: Steve W. Kerrigan

Publisher: BoD – Books on Demand

Published: 2015-11-18

Total Pages: 250

ISBN-13: 9535122088

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Platelets play a key role in thrombosis and haemostasis. However recent evidence clearly demonstrates that the functional role of platelets extends to many other processes in the body. With an internationally recognised list of contributing authors, The Non-Thrombotic Role of Platelets in Health and Disease, is a unique and definitive source of state-of-the-art knowledge about the additional role of platelets outside thrombosis and haemostasis. The intended audience for The Non-Thrombotic Role of Platelets in Health and Disease includes platelet biologists, microbiologists, immunologists, haematologists, oncologists, respiratory physicians, cardiologists, neurobiologists, tissue engineers, as well as students and fellows in these areas.


Book Synopsis The Non-Thrombotic Role of Platelets in Health and Disease by : Steve W. Kerrigan

Download or read book The Non-Thrombotic Role of Platelets in Health and Disease written by Steve W. Kerrigan and published by BoD – Books on Demand. This book was released on 2015-11-18 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelets play a key role in thrombosis and haemostasis. However recent evidence clearly demonstrates that the functional role of platelets extends to many other processes in the body. With an internationally recognised list of contributing authors, The Non-Thrombotic Role of Platelets in Health and Disease, is a unique and definitive source of state-of-the-art knowledge about the additional role of platelets outside thrombosis and haemostasis. The intended audience for The Non-Thrombotic Role of Platelets in Health and Disease includes platelet biologists, microbiologists, immunologists, haematologists, oncologists, respiratory physicians, cardiologists, neurobiologists, tissue engineers, as well as students and fellows in these areas.

Platelets in Cardiovascular Disease

Platelets in Cardiovascular Disease

Author: Deepak L. Bhatt

Publisher: Imperial College Press

Published: 2008

Total Pages: 235

ISBN-13: 1860948529

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Platelets in Cardiovascular Disease provides an in-depth and current coverage of relevant platelet biology and antiplatelet therapy that is in clinical use today and potentially for the future. The book provides a succinct overview of the critical role of platelets in cardiovascular medicine. Cardiovascular disease is the leading cause of mortality worldwide, and recent research has found that the platelet is central to the genesis of heart attacks and stroke as well as many of the complications of angioplasty and bypass surgery. An explosion of knowledge of the biology of platelets has established their important role in the formation of blood clots and, perhaps more intriguingly, their role as inflammatory cells. This growth in information has been paralleled by the development of several drugs that can interfere with platelet action and thereby improve patient outcomes. Indeed, several antiplatelet drugs already in development may ultimately lead to marked advances in both the treatment and prevention of cardiovascular disease. Drawing upon a panel of international experts, Platelets in Cardiovascular Disease delivers a concise yet thorough review of the major developments in antiplatelet therapy. Practicing clinicians as well as those involved in the development of new antithrombotic therapies will find the book interesting and useful. Sample Chapter(s). Chapter 1: Platelet Biology the Role of Platelets in Hemostasis, Thrombosis and Inflammation (274 KB). Contents: Platelet Biology: The Role of Platelets in Hemostasis, Thrombosis and Inflammation (R C Becker); Thromboxane Antagonists (B R Dulin & S R Steinhubl); Glycoprotein IIb/IIIa Inhibitors (S J Lehman et al.); ADP Receptor Antagonists (J Karha & C P Cannon); Monitoring Antiplatelet Therapy (P Harrison & A D Michelson); Platelet Genomics (B K Jefferson et al.); Future Strategies for the Development of Antiplatelet Drugs (R A Harrington). Readership: Physicians: cardiologists, vascular medicine specialists, hematologists; physicians in training: fellows, residents, interns; pharmacists; pharmaceutical industry: scientists, sales representatives.


Book Synopsis Platelets in Cardiovascular Disease by : Deepak L. Bhatt

Download or read book Platelets in Cardiovascular Disease written by Deepak L. Bhatt and published by Imperial College Press. This book was released on 2008 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelets in Cardiovascular Disease provides an in-depth and current coverage of relevant platelet biology and antiplatelet therapy that is in clinical use today and potentially for the future. The book provides a succinct overview of the critical role of platelets in cardiovascular medicine. Cardiovascular disease is the leading cause of mortality worldwide, and recent research has found that the platelet is central to the genesis of heart attacks and stroke as well as many of the complications of angioplasty and bypass surgery. An explosion of knowledge of the biology of platelets has established their important role in the formation of blood clots and, perhaps more intriguingly, their role as inflammatory cells. This growth in information has been paralleled by the development of several drugs that can interfere with platelet action and thereby improve patient outcomes. Indeed, several antiplatelet drugs already in development may ultimately lead to marked advances in both the treatment and prevention of cardiovascular disease. Drawing upon a panel of international experts, Platelets in Cardiovascular Disease delivers a concise yet thorough review of the major developments in antiplatelet therapy. Practicing clinicians as well as those involved in the development of new antithrombotic therapies will find the book interesting and useful. Sample Chapter(s). Chapter 1: Platelet Biology the Role of Platelets in Hemostasis, Thrombosis and Inflammation (274 KB). Contents: Platelet Biology: The Role of Platelets in Hemostasis, Thrombosis and Inflammation (R C Becker); Thromboxane Antagonists (B R Dulin & S R Steinhubl); Glycoprotein IIb/IIIa Inhibitors (S J Lehman et al.); ADP Receptor Antagonists (J Karha & C P Cannon); Monitoring Antiplatelet Therapy (P Harrison & A D Michelson); Platelet Genomics (B K Jefferson et al.); Future Strategies for the Development of Antiplatelet Drugs (R A Harrington). Readership: Physicians: cardiologists, vascular medicine specialists, hematologists; physicians in training: fellows, residents, interns; pharmacists; pharmaceutical industry: scientists, sales representatives.

Inflammation, Hemostasis, and Blood Conservation Strategies

Inflammation, Hemostasis, and Blood Conservation Strategies

Author: Jerrold H. Levy

Publisher: W B Saunders Company

Published: 2007

Total Pages: 206

ISBN-13: 9781416043225

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This issue reviews inflammation, hemostasis, and blood conservation strategies in patients following surgery, trauma, or complex injuries, and focuses on coagulopathies due to multiple factors including hemorrhage, surgical injuries, or drugs that affect the hemostatic system. Hemostasis and therapeutic approaches for bleeding and medical patients are discussed, including important aspects of thrombin signaling, protease activated receptor involvement, platelet dysfunction, and clot stabilization.The increasing problem of heparin-induced thrombocytopenia as a prothrombotic disease is discussed. Different approaches to reduce bleeding and transfusion requirements in critically ill patients are included based on either preventing or reversing the defects associated with coagulopathies. Blood conservation and the risks of transfusions are reviewed, including an update on transfusion-related acute lung injury. Pharmacologic approaches, an important aspect of blood conservation and are reviewed, including the recent New England Journal of Medicine controversy about aprotinin. Strategies involved in blood conservation in critically ill patients is included with focus on pharmacologic blood-sparing studies. Multiple pharmacologic approaches to reducing and treating bleeding are reviewed. Current and future pharmacologic approaches to attenuating hemostatic system activation, inflammation, and bleeding, and the potential need for allogeneic blood administration are important focuses of this issue.


Book Synopsis Inflammation, Hemostasis, and Blood Conservation Strategies by : Jerrold H. Levy

Download or read book Inflammation, Hemostasis, and Blood Conservation Strategies written by Jerrold H. Levy and published by W B Saunders Company. This book was released on 2007 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue reviews inflammation, hemostasis, and blood conservation strategies in patients following surgery, trauma, or complex injuries, and focuses on coagulopathies due to multiple factors including hemorrhage, surgical injuries, or drugs that affect the hemostatic system. Hemostasis and therapeutic approaches for bleeding and medical patients are discussed, including important aspects of thrombin signaling, protease activated receptor involvement, platelet dysfunction, and clot stabilization.The increasing problem of heparin-induced thrombocytopenia as a prothrombotic disease is discussed. Different approaches to reduce bleeding and transfusion requirements in critically ill patients are included based on either preventing or reversing the defects associated with coagulopathies. Blood conservation and the risks of transfusions are reviewed, including an update on transfusion-related acute lung injury. Pharmacologic approaches, an important aspect of blood conservation and are reviewed, including the recent New England Journal of Medicine controversy about aprotinin. Strategies involved in blood conservation in critically ill patients is included with focus on pharmacologic blood-sparing studies. Multiple pharmacologic approaches to reducing and treating bleeding are reviewed. Current and future pharmacologic approaches to attenuating hemostatic system activation, inflammation, and bleeding, and the potential need for allogeneic blood administration are important focuses of this issue.

Platelet Function and Thrombosis

Platelet Function and Thrombosis

Author: Pier Mannuccio Mannucci

Publisher: Springer

Published: 1972

Total Pages: 384

ISBN-13:

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The special contribution of the present volume is that of gathering a large amount of up-to-date information on the formidable problem of the methods used for testing platelet function in thrombosis. The methods used for studying platelet behavior in hemorrhagic disorders due to abnormal platelet function are undoubtedly characterized by difficulties in interpretation and by poor reproducibility. However, all will agree that the problem of the significance and importance of platelet function tests in thrombosis and atherosclerosis is an absolute "morass," and recent and past papers on the measurement of platelet adhesiveness in myocardial infarction could well appear in a special issue of the new "Journal of Irreproducible Results". This volume includes both general papers on the role of platelets in thrombosis by G. V. R. Born, Duncan P. Thomas, and J. R.


Book Synopsis Platelet Function and Thrombosis by : Pier Mannuccio Mannucci

Download or read book Platelet Function and Thrombosis written by Pier Mannuccio Mannucci and published by Springer. This book was released on 1972 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The special contribution of the present volume is that of gathering a large amount of up-to-date information on the formidable problem of the methods used for testing platelet function in thrombosis. The methods used for studying platelet behavior in hemorrhagic disorders due to abnormal platelet function are undoubtedly characterized by difficulties in interpretation and by poor reproducibility. However, all will agree that the problem of the significance and importance of platelet function tests in thrombosis and atherosclerosis is an absolute "morass," and recent and past papers on the measurement of platelet adhesiveness in myocardial infarction could well appear in a special issue of the new "Journal of Irreproducible Results". This volume includes both general papers on the role of platelets in thrombosis by G. V. R. Born, Duncan P. Thomas, and J. R.