Pain Management and the Opioid Epidemic

Pain Management and the Opioid Epidemic

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2017-09-28

Total Pages: 483

ISBN-13: 0309459575

DOWNLOAD EBOOK

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.


Book Synopsis Pain Management and the Opioid Epidemic by : National Academies of Sciences, Engineering, and Medicine

Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.


Pain Killer

Pain Killer

Author: Barry Meier

Publisher: Rodale

Published: 2003-10-17

Total Pages: 348

ISBN-13: 9781579546380

DOWNLOAD EBOOK

Examines OxyContin, the so-called miracle prescription drug that swept the nation but led to overdoes and addiction, providing a look at the multi-billion-dollar pain managment business, its excesses and its abuses.


Book Synopsis Pain Killer by : Barry Meier

Download or read book Pain Killer written by Barry Meier and published by Rodale. This book was released on 2003-10-17 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines OxyContin, the so-called miracle prescription drug that swept the nation but led to overdoes and addiction, providing a look at the multi-billion-dollar pain managment business, its excesses and its abuses.


Prescription Painkillers

Prescription Painkillers

Author: Marvin D Seppala

Publisher: Simon and Schuster

Published: 2011-01-25

Total Pages: 272

ISBN-13: 1592859933

DOWNLOAD EBOOK

The definitive book about the impact of prescription painkiller abuse on individuals, communities, and society by one of America's leading experts on addiction. In recent years, the media has inundated us with coverage of the increasing abuse of prescription painkillers. Prescription Painkillers, the third book in Hazelden's Library of Addictive Drugs series, offers current, comprehensive information on the history, social impact, pharmacology, and addiction treatment for commonly abused, highly addictive opiate prescription painkillers such as Oxycontin®, Vicodin, Percocet, and Darvocet.Marvin D. Seppala, MD, provides context for understanding the current drug abuse problem by tracing the history of opioids and the varying patterns of use over time. He then offers an in-depth study of controversial issues surrounding these readily available drugs, including over-prescription by physicians and adolescent abuse. Also included is a straightforward look at the leading treatment protocols based on current research.


Book Synopsis Prescription Painkillers by : Marvin D Seppala

Download or read book Prescription Painkillers written by Marvin D Seppala and published by Simon and Schuster. This book was released on 2011-01-25 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive book about the impact of prescription painkiller abuse on individuals, communities, and society by one of America's leading experts on addiction. In recent years, the media has inundated us with coverage of the increasing abuse of prescription painkillers. Prescription Painkillers, the third book in Hazelden's Library of Addictive Drugs series, offers current, comprehensive information on the history, social impact, pharmacology, and addiction treatment for commonly abused, highly addictive opiate prescription painkillers such as Oxycontin®, Vicodin, Percocet, and Darvocet.Marvin D. Seppala, MD, provides context for understanding the current drug abuse problem by tracing the history of opioids and the varying patterns of use over time. He then offers an in-depth study of controversial issues surrounding these readily available drugs, including over-prescription by physicians and adolescent abuse. Also included is a straightforward look at the leading treatment protocols based on current research.


When Painkillers Become Dangerous

When Painkillers Become Dangerous

Author: Drew Pinsky

Publisher: Simon and Schuster

Published: 2009-06-03

Total Pages: 192

ISBN-13: 1592857787

DOWNLOAD EBOOK

The coronavirus pandemic joined other crises already in process--including America's epidemic of opioid addiction. Added stress and anxiety and reduced access to timely treatments only adds to the problem. Here's practical information about painkillers from treatment professionals. A timely guide to the misuse and abuse of prescription painkillers that sorts the facts from the fiction for legitimate users and their loved ones. If you are concerned about a loved one's use of pain medications, you need to read this book, When Painkillers Become Dangerous Whether prescribed by a physician as OxyContin or purchased on the street as "hillbilly heroin," painkilling drugs are extremely effective in eliminating physical, emotional, and psychological distress. The problem is that these drugs are also incredibly addictive. Misuse of and addiction to prescription pain medications has become America's latest, complex, and alarming drug abuse trend. In fact, an estimated 2.6 million people currently use prescription pain relievers non-medically-a dangerous practice that could quickly reach epidemic proportions. Best-selling author Drew Pinsky, M.D., and five other leading experts offer practical, plainspoken, and much-needed information about addiction to painkilling drugs. They will help you understand:How addiction to painkilling medication developsWhat to do if a family member is addictedWhat happens in addiction treatmentWhy addiction is a family disease


Book Synopsis When Painkillers Become Dangerous by : Drew Pinsky

Download or read book When Painkillers Become Dangerous written by Drew Pinsky and published by Simon and Schuster. This book was released on 2009-06-03 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: The coronavirus pandemic joined other crises already in process--including America's epidemic of opioid addiction. Added stress and anxiety and reduced access to timely treatments only adds to the problem. Here's practical information about painkillers from treatment professionals. A timely guide to the misuse and abuse of prescription painkillers that sorts the facts from the fiction for legitimate users and their loved ones. If you are concerned about a loved one's use of pain medications, you need to read this book, When Painkillers Become Dangerous Whether prescribed by a physician as OxyContin or purchased on the street as "hillbilly heroin," painkilling drugs are extremely effective in eliminating physical, emotional, and psychological distress. The problem is that these drugs are also incredibly addictive. Misuse of and addiction to prescription pain medications has become America's latest, complex, and alarming drug abuse trend. In fact, an estimated 2.6 million people currently use prescription pain relievers non-medically-a dangerous practice that could quickly reach epidemic proportions. Best-selling author Drew Pinsky, M.D., and five other leading experts offer practical, plainspoken, and much-needed information about addiction to painkilling drugs. They will help you understand:How addiction to painkilling medication developsWhat to do if a family member is addictedWhat happens in addiction treatmentWhy addiction is a family disease


WHO Guidelines for the Pharmacological and Radiotherapeutic Management of Cancer Pain in Adults and Adolescents

WHO Guidelines for the Pharmacological and Radiotherapeutic Management of Cancer Pain in Adults and Adolescents

Author: World Health Organization

Publisher:

Published: 1981

Total Pages: 0

ISBN-13:

DOWNLOAD EBOOK


Book Synopsis WHO Guidelines for the Pharmacological and Radiotherapeutic Management of Cancer Pain in Adults and Adolescents by : World Health Organization

Download or read book WHO Guidelines for the Pharmacological and Radiotherapeutic Management of Cancer Pain in Adults and Adolescents written by World Health Organization and published by . This book was released on 1981 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Pain Killer

Pain Killer

Author: Barry Meier

Publisher: Random House

Published: 2018-05-29

Total Pages: 241

ISBN-13: 0525511091

DOWNLOAD EBOOK

From the Pulitzer Prize–winning New York Times reporter who first exposed the roots of the opioid epidemic and the secretive world of the Sackler family behind Purdue Pharma, Pain Killer is the celebrated landmark story of corporate greed and government negligence that inspired an upcoming Netflix series. “This is the book that started it all. Barry Meier is a heroic reporter and Pain Killer is a muckraking classic.”—Patrick Radden Keefe, author of Empire of Pain Between 1999 and 2017, an estimated 250,000 Americans died from overdoses involving prescription painkillers, a plague ignited by Purdue Pharma’s aggressive marketing of OxyContin. Families, working class and wealthy, have been torn apart, businesses destroyed, and public officials pushed to the brink. Meanwhile, the drugmaker’s owners, Raymond and Mortimer Sackler, whose names adorn museums worldwide, made enormous fortunes from the commercial success of OxyContin. In Pain Killer, Barry Meier tells the story of how Purdue turned OxyContin into a billion-dollar blockbuster. Powerful narcotic painkillers, or opioids, were once used as drugs of last resort for pain sufferers. But Purdue launched an unprecedented marketing campaign claiming that the drug’s long-acting formulation made it safer to use than traditional painkillers for many types of pain. That illusion was quickly shattered as drug abusers learned that crushing an Oxy could release its narcotic payload all at once. Even in its prescribed form, Oxy proved fiercely addictive. As OxyContin’s use and abuse grew, Purdue concealed what it knew from regulators, doctors, and patients. Here are the people who profited from the crisis and those who paid the price, those who plotted in boardrooms and those who tried to sound alarm bells. A country doctor in rural Virginia, Art Van Zee, took on Purdue and warned officials about OxyContin abuse. An ebullient high school cheerleader, Lindsey Myers, was reduced to stealing from her parents to feed her escalating Oxy habit. A hard-charging DEA official, Laura Nagel, tried to hold Purdue executives to account. In Pain Killer, Barry Meier breaks new ground in his decades-long investigation into the opioid epidemic. He takes readers inside Purdue to show how long the company withheld information about the abuse of OxyContin and gives a shocking account of the Justice Department’s failure to alter the trajectory of the opioid epidemic and protect thousands of lives. Equal parts crime thriller, medical detective story, and business exposé, Pain Killer is a hard-hitting look at how a supposed wonder drug became the gateway drug to a national tragedy.


Book Synopsis Pain Killer by : Barry Meier

Download or read book Pain Killer written by Barry Meier and published by Random House. This book was released on 2018-05-29 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the Pulitzer Prize–winning New York Times reporter who first exposed the roots of the opioid epidemic and the secretive world of the Sackler family behind Purdue Pharma, Pain Killer is the celebrated landmark story of corporate greed and government negligence that inspired an upcoming Netflix series. “This is the book that started it all. Barry Meier is a heroic reporter and Pain Killer is a muckraking classic.”—Patrick Radden Keefe, author of Empire of Pain Between 1999 and 2017, an estimated 250,000 Americans died from overdoses involving prescription painkillers, a plague ignited by Purdue Pharma’s aggressive marketing of OxyContin. Families, working class and wealthy, have been torn apart, businesses destroyed, and public officials pushed to the brink. Meanwhile, the drugmaker’s owners, Raymond and Mortimer Sackler, whose names adorn museums worldwide, made enormous fortunes from the commercial success of OxyContin. In Pain Killer, Barry Meier tells the story of how Purdue turned OxyContin into a billion-dollar blockbuster. Powerful narcotic painkillers, or opioids, were once used as drugs of last resort for pain sufferers. But Purdue launched an unprecedented marketing campaign claiming that the drug’s long-acting formulation made it safer to use than traditional painkillers for many types of pain. That illusion was quickly shattered as drug abusers learned that crushing an Oxy could release its narcotic payload all at once. Even in its prescribed form, Oxy proved fiercely addictive. As OxyContin’s use and abuse grew, Purdue concealed what it knew from regulators, doctors, and patients. Here are the people who profited from the crisis and those who paid the price, those who plotted in boardrooms and those who tried to sound alarm bells. A country doctor in rural Virginia, Art Van Zee, took on Purdue and warned officials about OxyContin abuse. An ebullient high school cheerleader, Lindsey Myers, was reduced to stealing from her parents to feed her escalating Oxy habit. A hard-charging DEA official, Laura Nagel, tried to hold Purdue executives to account. In Pain Killer, Barry Meier breaks new ground in his decades-long investigation into the opioid epidemic. He takes readers inside Purdue to show how long the company withheld information about the abuse of OxyContin and gives a shocking account of the Justice Department’s failure to alter the trajectory of the opioid epidemic and protect thousands of lives. Equal parts crime thriller, medical detective story, and business exposé, Pain Killer is a hard-hitting look at how a supposed wonder drug became the gateway drug to a national tragedy.


Prescription Painkillers

Prescription Painkillers

Author: Rosa Waters

Publisher: Simon and Schuster

Published: 2014-11-17

Total Pages: 48

ISBN-13: 1422288129

DOWNLOAD EBOOK

Just because a drug is legal, doesn't mean it's safe to abuse it. Abusing prescription painkillers like OxyContin™, Percocet™, and Vicodin™ is no safer than trying much harder drugs. These drugs are being vastly abused and represent one of today's largest drug epidemics. Discover the real consequences of taking prescription painkillers to get high. Learn about the damage these pills can do to your body and how you can develop an addiction to painkillers. Find out about the downside of prescription painkillers!


Book Synopsis Prescription Painkillers by : Rosa Waters

Download or read book Prescription Painkillers written by Rosa Waters and published by Simon and Schuster. This book was released on 2014-11-17 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt: Just because a drug is legal, doesn't mean it's safe to abuse it. Abusing prescription painkillers like OxyContin™, Percocet™, and Vicodin™ is no safer than trying much harder drugs. These drugs are being vastly abused and represent one of today's largest drug epidemics. Discover the real consequences of taking prescription painkillers to get high. Learn about the damage these pills can do to your body and how you can develop an addiction to painkillers. Find out about the downside of prescription painkillers!


Empire of Pain

Empire of Pain

Author: Patrick Radden Keefe

Publisher: Anchor

Published: 2021-04-13

Total Pages: 574

ISBN-13: 038554569X

DOWNLOAD EBOOK

NEW YORK TIMES BESTSELLER • A NEW YORK TIMES NOTABLE BOOK OF THE YEAR • A grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. From the prize-winning and bestselling author of Say Nothing. "A real-life version of the HBO series Succession with a lethal sting in its tail…a masterful work of narrative reportage.” – Laura Miller, Slate The history of the Sackler dynasty is rife with drama—baroque personal lives; bitter disputes over estates; fistfights in boardrooms; glittering art collections; Machiavellian courtroom maneuvers; and the calculated use of money to burnish reputations and crush the less powerful. The Sackler name has adorned the walls of many storied institutions—Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, but the source of the family fortune was vague—until it emerged that the Sacklers were responsible for making and marketing a blockbuster painkiller that was the catalyst for the opioid crisis. Empire of Pain is the saga of three generations of a single family and the mark they would leave on the world, a tale that moves from the bustling streets of early twentieth-century Brooklyn to the seaside palaces of Greenwich, Connecticut, and Cap d’Antibes to the corridors of power in Washington, D.C. It follows the family’s early success with Valium to the much more potent OxyContin, marketed with a ruthless technique of co-opting doctors, influencing the FDA, downplaying the drug’s addictiveness. Empire of Pain chronicles the multiple investigations of the Sacklers and their company, and the scorched-earth legal tactics that the family has used to evade accountability. A masterpiece of narrative reporting, Empire of Pain is a ferociously compelling portrait of America’s second Gilded Age, a study of impunity among the super-elite and a relentless investigation of the naked greed that built one of the world’s great fortunes.


Book Synopsis Empire of Pain by : Patrick Radden Keefe

Download or read book Empire of Pain written by Patrick Radden Keefe and published by Anchor. This book was released on 2021-04-13 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW YORK TIMES BESTSELLER • A NEW YORK TIMES NOTABLE BOOK OF THE YEAR • A grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. From the prize-winning and bestselling author of Say Nothing. "A real-life version of the HBO series Succession with a lethal sting in its tail…a masterful work of narrative reportage.” – Laura Miller, Slate The history of the Sackler dynasty is rife with drama—baroque personal lives; bitter disputes over estates; fistfights in boardrooms; glittering art collections; Machiavellian courtroom maneuvers; and the calculated use of money to burnish reputations and crush the less powerful. The Sackler name has adorned the walls of many storied institutions—Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, but the source of the family fortune was vague—until it emerged that the Sacklers were responsible for making and marketing a blockbuster painkiller that was the catalyst for the opioid crisis. Empire of Pain is the saga of three generations of a single family and the mark they would leave on the world, a tale that moves from the bustling streets of early twentieth-century Brooklyn to the seaside palaces of Greenwich, Connecticut, and Cap d’Antibes to the corridors of power in Washington, D.C. It follows the family’s early success with Valium to the much more potent OxyContin, marketed with a ruthless technique of co-opting doctors, influencing the FDA, downplaying the drug’s addictiveness. Empire of Pain chronicles the multiple investigations of the Sacklers and their company, and the scorched-earth legal tactics that the family has used to evade accountability. A masterpiece of narrative reporting, Empire of Pain is a ferociously compelling portrait of America’s second Gilded Age, a study of impunity among the super-elite and a relentless investigation of the naked greed that built one of the world’s great fortunes.


The King of Sports

The King of Sports

Author: Gregg Easterbrook

Publisher: Macmillan

Published: 2013-09-24

Total Pages: 368

ISBN-13: 125001171X

DOWNLOAD EBOOK

"Gregg Easterbrook is one of the country's best-known football commentators, having analyzed football on-air for ESPN and the NFL Network. MSNBC calls his ESPN blog "the best and most compelling football column anywhere." The King of Sports takes an expansive look at our biggest sport. Easterbrook explores these and many other topics: The real harm done by concussions (It's not to NFL players) The real way in which college football players are exploited (It's not by not being paid) The reason football helps American colleges to be great institutions (It's not bowl revenue.) The way football has aided the revival of American cities (It's not Super Bowl trophies) The hidden scandal of the NFL (You'll have to read the book) Using his year-long exclusive insider access to the Virginia Tech football program, where Frank Beamer has compiled the most victories of any active NFL or college head coach, Easterbrook shows how VT does things right. Then he reports on all the things wrong with football and moves to examples of how the sport can be reformed to keep it just as popular and exciting, but not as notorious. Rich with reporting details from interviews with current and former college and pro football players and coaches. The King of Sports promises to be the most provocative and best-read sports book of the year"--


Book Synopsis The King of Sports by : Gregg Easterbrook

Download or read book The King of Sports written by Gregg Easterbrook and published by Macmillan. This book was released on 2013-09-24 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Gregg Easterbrook is one of the country's best-known football commentators, having analyzed football on-air for ESPN and the NFL Network. MSNBC calls his ESPN blog "the best and most compelling football column anywhere." The King of Sports takes an expansive look at our biggest sport. Easterbrook explores these and many other topics: The real harm done by concussions (It's not to NFL players) The real way in which college football players are exploited (It's not by not being paid) The reason football helps American colleges to be great institutions (It's not bowl revenue.) The way football has aided the revival of American cities (It's not Super Bowl trophies) The hidden scandal of the NFL (You'll have to read the book) Using his year-long exclusive insider access to the Virginia Tech football program, where Frank Beamer has compiled the most victories of any active NFL or college head coach, Easterbrook shows how VT does things right. Then he reports on all the things wrong with football and moves to examples of how the sport can be reformed to keep it just as popular and exciting, but not as notorious. Rich with reporting details from interviews with current and former college and pro football players and coaches. The King of Sports promises to be the most provocative and best-read sports book of the year"--


Drug-Induced Liver Injury

Drug-Induced Liver Injury

Author:

Publisher: Academic Press

Published: 2019-07-13

Total Pages: 288

ISBN-13: 0128173173

DOWNLOAD EBOOK

Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series


Book Synopsis Drug-Induced Liver Injury by :

Download or read book Drug-Induced Liver Injury written by and published by Academic Press. This book was released on 2019-07-13 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series