Prostacyclin and Hypertension

Prostacyclin and Hypertension

Author: Gerd Bönner

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 131

ISBN-13: 3642956084

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The aim of present-day treatment of hypertension is no longer as the effective reduction of blood pressure, regarded merely but as the ever-increasing application of new therapeutic prin ciples to prevent such consequences of hypertension as left heart hypertrophy, medial hypertrophy of the vessels and ar teriosclerosis. In this context special attention has been di rected to stimulation of the endogenous vasocilator hormonal systems such as the prostaglandins. The great interest in our book, which has meanwhile appeared in a French edition, seems to confirm this trend and has encouraged us to include in the book the new findings published in the last twelve months. These changes and additions maintain the current status of the book and provide an even more complete survey of the available information about prostacyclin in hyperten sion. We wish to thank all those colleagues who have made useful suggestions for this second edition, as well as Springer Verlag and its associates, who ensured a uniformly smooth passage in the production of the book. Cologne and MUnster, January 1990 Gerd Bonner Karl-Heinz Rahn v Preface to the First Edition Diseases of the heart and circulation currently constitute the commonest causes of death in our population. Hypertension, as evidenced by a pathologic increase in blood pressure, is one of the most important risk factors. Primary hypertension can be established in about 15 % of adults. Patients with hyperten sion usually feel well subjectively and only rarely complain of symptoms.


Book Synopsis Prostacyclin and Hypertension by : Gerd Bönner

Download or read book Prostacyclin and Hypertension written by Gerd Bönner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of present-day treatment of hypertension is no longer as the effective reduction of blood pressure, regarded merely but as the ever-increasing application of new therapeutic prin ciples to prevent such consequences of hypertension as left heart hypertrophy, medial hypertrophy of the vessels and ar teriosclerosis. In this context special attention has been di rected to stimulation of the endogenous vasocilator hormonal systems such as the prostaglandins. The great interest in our book, which has meanwhile appeared in a French edition, seems to confirm this trend and has encouraged us to include in the book the new findings published in the last twelve months. These changes and additions maintain the current status of the book and provide an even more complete survey of the available information about prostacyclin in hyperten sion. We wish to thank all those colleagues who have made useful suggestions for this second edition, as well as Springer Verlag and its associates, who ensured a uniformly smooth passage in the production of the book. Cologne and MUnster, January 1990 Gerd Bonner Karl-Heinz Rahn v Preface to the First Edition Diseases of the heart and circulation currently constitute the commonest causes of death in our population. Hypertension, as evidenced by a pathologic increase in blood pressure, is one of the most important risk factors. Primary hypertension can be established in about 15 % of adults. Patients with hyperten sion usually feel well subjectively and only rarely complain of symptoms.

Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension

Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension

Author: Toshio Nakanishi

Publisher: Springer Nature

Published: 2020-02-28

Total Pages: 374

ISBN-13: 9811511853

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This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.


Book Synopsis Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension by : Toshio Nakanishi

Download or read book Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension written by Toshio Nakanishi and published by Springer Nature. This book was released on 2020-02-28 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.

Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

Author: Jochen Antel

Publisher: IOS Press

Published: 2010

Total Pages: 116

ISBN-13: 1607506017

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Pulmonary hypertension is a fatal lung and heart disease. It is characterized by shortness of breath, fatigue and fainting. It is exacerbated by an increase of the pressure in the lung vasculature through exercise, leading to progressive worsening of hemodynamics, right ventricular hypertrophy, right heart insufficiency and finally right heart failure. This book focuses on pulmonary arterial hypertension, a rare and progressive subgroup of pulmonary hypertension, which is today incurable and terminally faal. Classification of pulmonary arterial hypertension, its pathology, and strategies for future therapy will be of interest both to those suffering from the disease and those who take care of patients. This volume will also engage physicians and other scientists contributing to an understanding of the pathophysiology of pulmonary arterial hypertension and attempting to extend life of humans with pulmonary arterial hypertension by developing causal and curative therapies.


Book Synopsis Pulmonary Arterial Hypertension by : Jochen Antel

Download or read book Pulmonary Arterial Hypertension written by Jochen Antel and published by IOS Press. This book was released on 2010 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pulmonary hypertension is a fatal lung and heart disease. It is characterized by shortness of breath, fatigue and fainting. It is exacerbated by an increase of the pressure in the lung vasculature through exercise, leading to progressive worsening of hemodynamics, right ventricular hypertrophy, right heart insufficiency and finally right heart failure. This book focuses on pulmonary arterial hypertension, a rare and progressive subgroup of pulmonary hypertension, which is today incurable and terminally faal. Classification of pulmonary arterial hypertension, its pathology, and strategies for future therapy will be of interest both to those suffering from the disease and those who take care of patients. This volume will also engage physicians and other scientists contributing to an understanding of the pathophysiology of pulmonary arterial hypertension and attempting to extend life of humans with pulmonary arterial hypertension by developing causal and curative therapies.

Pulmonary Hypertension

Pulmonary Hypertension

Author: Norbert F. Voelkel

Publisher: PMPH-USA

Published: 2011

Total Pages: 380

ISBN-13: 9781607950370

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Pulmonary hypertension is a world�wide problem which is gaining greater attention and is more frequently diagnosed now, more than the past ten or twenty years, because of the use and interpretation of echocardiograms. Pulmonary Hypertension raises questions and discusses concepts which will address the issue of etiology of pulmonary hypertension, its pathobiology with its close proximity to cancer, and the consequences of severe PH which is right heart failure and death.


Book Synopsis Pulmonary Hypertension by : Norbert F. Voelkel

Download or read book Pulmonary Hypertension written by Norbert F. Voelkel and published by PMPH-USA. This book was released on 2011 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pulmonary hypertension is a world�wide problem which is gaining greater attention and is more frequently diagnosed now, more than the past ten or twenty years, because of the use and interpretation of echocardiograms. Pulmonary Hypertension raises questions and discusses concepts which will address the issue of etiology of pulmonary hypertension, its pathobiology with its close proximity to cancer, and the consequences of severe PH which is right heart failure and death.

Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

Author: Simon Stewart

Publisher: CRC Press

Published: 2004-12-22

Total Pages: 58

ISBN-13: 1841843547

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This pocketbook is a concise summary of latest evidence-based information on the diagnosis, assessment and treatment of pulmonary arterial hypertension. Dr Simon Stewart is one of the world's leading nursing experts on cardiac disease, especially heart failure. Highly illustrated, clearly and succinctly written, the book provides an introduction to pulmonary arterial hypertension. It contains clear guidelines for the effective treatment of pulmonary arterial hypertension and emphasizes the need for screening of high-risk patients and outlines the range and effectiveness of treatment options once PAH has been diagnosed.


Book Synopsis Pulmonary Arterial Hypertension by : Simon Stewart

Download or read book Pulmonary Arterial Hypertension written by Simon Stewart and published by CRC Press. This book was released on 2004-12-22 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt: This pocketbook is a concise summary of latest evidence-based information on the diagnosis, assessment and treatment of pulmonary arterial hypertension. Dr Simon Stewart is one of the world's leading nursing experts on cardiac disease, especially heart failure. Highly illustrated, clearly and succinctly written, the book provides an introduction to pulmonary arterial hypertension. It contains clear guidelines for the effective treatment of pulmonary arterial hypertension and emphasizes the need for screening of high-risk patients and outlines the range and effectiveness of treatment options once PAH has been diagnosed.

Treatment of Pulmonary Hypertension

Treatment of Pulmonary Hypertension

Author: Brendan Madden

Publisher: Springer

Published: 2015-08-10

Total Pages: 188

ISBN-13: 3319135813

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​This title will be presented as highly practical information on pharmaceutical options in pulmonary hypertension, written in a quick-access, no-nonsense format. The emphasis will be on a just-the-facts clinical approach, heavy on tabular material, light on dense prose. The involvement of the ISCP will ensure that the best quality contributors will be involved and establish a consistent approach to each topic in the series. Each volume is designed to be between 100 and 150 pages containing practical illustrations and designed to improve understand and practical usage of cardiovascular drugs in specific clinical areas.​


Book Synopsis Treatment of Pulmonary Hypertension by : Brendan Madden

Download or read book Treatment of Pulmonary Hypertension written by Brendan Madden and published by Springer. This book was released on 2015-08-10 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​This title will be presented as highly practical information on pharmaceutical options in pulmonary hypertension, written in a quick-access, no-nonsense format. The emphasis will be on a just-the-facts clinical approach, heavy on tabular material, light on dense prose. The involvement of the ISCP will ensure that the best quality contributors will be involved and establish a consistent approach to each topic in the series. Each volume is designed to be between 100 and 150 pages containing practical illustrations and designed to improve understand and practical usage of cardiovascular drugs in specific clinical areas.​

Hepatotoxicity

Hepatotoxicity

Author: Hyman J. Zimmerman

Publisher: Lippincott Williams & Wilkins

Published: 1999

Total Pages: 848

ISBN-13: 9780781719520

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Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.


Book Synopsis Hepatotoxicity by : Hyman J. Zimmerman

Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Prostacyclin and iloprost in the treatment of primary pulmonary hypertension

Prostacyclin and iloprost in the treatment of primary pulmonary hypertension

Author: T. W. Higenbottam

Publisher:

Published: 1997

Total Pages: 28

ISBN-13: 9781900733106

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Book Synopsis Prostacyclin and iloprost in the treatment of primary pulmonary hypertension by : T. W. Higenbottam

Download or read book Prostacyclin and iloprost in the treatment of primary pulmonary hypertension written by T. W. Higenbottam and published by . This book was released on 1997 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pulmonary Hypertension

Pulmonary Hypertension

Author: Bradley A. Maron

Publisher: Springer

Published: 2015-11-02

Total Pages: 371

ISBN-13: 331923594X

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This book provides the framework for a singular reference in the field of pulmonary hypertension. Pulmonary vascular disease is a complex and heterogeneous condition characterized by remodeling of distal pulmonary arterioles that increases pulmonary vascular resistance to affect cardiopulmonary hemodynamic and right ventricular function adversely, resulting in a clinical syndrome of diminished exercise tolerance, shortness of breath, and heart failure-associated morbidity and mortality. Owing to the availability of novel pulmonary circulation-selective pharmacotherapies over the previous decade, the number of pulmonary hypertension patients eligible for treatment has increased substantially. Despite this progress, under-awareness persists within the practicing pulmonary, cardiovascular, and general internal medicine communities. This is due, in part, to the complex array of molecular mechanisms implicated in the pathobiology of PH, as well as cutting-edge discoveries from translational scientific works that provide a new framework by which to understand pulmonary vascular-right ventricular coupling. Taken together, a key educational opportunity is exposed to bridge this knowledge gap through the synthesis of a contemporary text that emphasizes basic science, translational and clinical principles, and treatment strategies for understanding pulmonary hypertension.


Book Synopsis Pulmonary Hypertension by : Bradley A. Maron

Download or read book Pulmonary Hypertension written by Bradley A. Maron and published by Springer. This book was released on 2015-11-02 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the framework for a singular reference in the field of pulmonary hypertension. Pulmonary vascular disease is a complex and heterogeneous condition characterized by remodeling of distal pulmonary arterioles that increases pulmonary vascular resistance to affect cardiopulmonary hemodynamic and right ventricular function adversely, resulting in a clinical syndrome of diminished exercise tolerance, shortness of breath, and heart failure-associated morbidity and mortality. Owing to the availability of novel pulmonary circulation-selective pharmacotherapies over the previous decade, the number of pulmonary hypertension patients eligible for treatment has increased substantially. Despite this progress, under-awareness persists within the practicing pulmonary, cardiovascular, and general internal medicine communities. This is due, in part, to the complex array of molecular mechanisms implicated in the pathobiology of PH, as well as cutting-edge discoveries from translational scientific works that provide a new framework by which to understand pulmonary vascular-right ventricular coupling. Taken together, a key educational opportunity is exposed to bridge this knowledge gap through the synthesis of a contemporary text that emphasizes basic science, translational and clinical principles, and treatment strategies for understanding pulmonary hypertension.

Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

Author: Clive Handler

Publisher: OUP Oxford

Published: 2010-06-24

Total Pages: 144

ISBN-13: 0191501468

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Pulmonary arterial hypertension (PAH) is a high blood pressure in the arteries that supply the lungs with blood. Patients with mild PAH, particularly young patients, may feel quite well and get breathless or tired only with vigorous exertion. Those with severe PAH may get breathless on minimal exertion and feel tired, exhausted and experience chest pain, forceful heart beats, dizzy turns, loss of appetite, and have swelling of the legs due to fluid retention. This book will help patients and their families understand what PAH is, and advise them on how to cope with their illness. In the UK patients with PAH are referred to one of the eight National Pulmonary Hypertension centres staffed by a team of specialist doctors, nurses, pharmacists, and other staff who are experienced and expert in managing all aspects of the condition. Currently, the drugs used to treat the condition can be prescribed only by these specialists. The book will explain what the illness is and how it is treated in a reassuring and understandable way. The book will also be of interest to GPs, nurses and other related healthcare professionals.


Book Synopsis Pulmonary Arterial Hypertension by : Clive Handler

Download or read book Pulmonary Arterial Hypertension written by Clive Handler and published by OUP Oxford. This book was released on 2010-06-24 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pulmonary arterial hypertension (PAH) is a high blood pressure in the arteries that supply the lungs with blood. Patients with mild PAH, particularly young patients, may feel quite well and get breathless or tired only with vigorous exertion. Those with severe PAH may get breathless on minimal exertion and feel tired, exhausted and experience chest pain, forceful heart beats, dizzy turns, loss of appetite, and have swelling of the legs due to fluid retention. This book will help patients and their families understand what PAH is, and advise them on how to cope with their illness. In the UK patients with PAH are referred to one of the eight National Pulmonary Hypertension centres staffed by a team of specialist doctors, nurses, pharmacists, and other staff who are experienced and expert in managing all aspects of the condition. Currently, the drugs used to treat the condition can be prescribed only by these specialists. The book will explain what the illness is and how it is treated in a reassuring and understandable way. The book will also be of interest to GPs, nurses and other related healthcare professionals.