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Proteomic Methods in Neuropsychiatric Research

Author: Paul C. Guest

Publisher: Springer

Published: 2017-03-28

Total Pages: 370

ISBN-13: 3319524798

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Due to continuous technical developments and new insights into the high complexity of neurological diseases, there is an increasing need for the application of proteomic technologies which can yield potential biomarker readouts for improved clinical management as well as for the development of new drugs by struggling pharmaceutical companies. This book describes the step-by-step use of proteomic methods such as two-dimensional gel electrophoresis, multiplex immunoassay, liquid chromatography mass spectrometry (LC-MS) and selective reaction monitoring MS, to increase our understanding of these diseases, with the ultimate aim of improving patient care. The volume will be of high interest to clinical scientists, physicians and pharmaceutical company scientists as it gives insights into the latest technologies enabling the revolution of personalized medicine. It is of direct interest to both technical and bench biomarker scientists as it gives step by step instructions on how to carry out each of the protocols. It is also of interest to researchers as each technique will be presented in the context of a specific neurological disorder, including Alzheimer's disease, multiple sclerosis, autism spectrum disorders, schizophrenia, major depressive disorder and bipolar disorder. Finally, it will also highlight the future research efforts in this field, which are endeavoring to convert proteomic platforms to the form of hand held devices which can be used in a point of care setting and return diagnostic results within the timeframe of a visit to the general practitioner.

Book Synopsis Proteomic Methods in Neuropsychiatric Research by : Paul C. Guest

Download or read book Proteomic Methods in Neuropsychiatric Research written by Paul C. Guest and published by Springer. This book was released on 2017-03-28 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to continuous technical developments and new insights into the high complexity of neurological diseases, there is an increasing need for the application of proteomic technologies which can yield potential biomarker readouts for improved clinical management as well as for the development of new drugs by struggling pharmaceutical companies. This book describes the step-by-step use of proteomic methods such as two-dimensional gel electrophoresis, multiplex immunoassay, liquid chromatography mass spectrometry (LC-MS) and selective reaction monitoring MS, to increase our understanding of these diseases, with the ultimate aim of improving patient care. The volume will be of high interest to clinical scientists, physicians and pharmaceutical company scientists as it gives insights into the latest technologies enabling the revolution of personalized medicine. It is of direct interest to both technical and bench biomarker scientists as it gives step by step instructions on how to carry out each of the protocols. It is also of interest to researchers as each technique will be presented in the context of a specific neurological disorder, including Alzheimer's disease, multiple sclerosis, autism spectrum disorders, schizophrenia, major depressive disorder and bipolar disorder. Finally, it will also highlight the future research efforts in this field, which are endeavoring to convert proteomic platforms to the form of hand held devices which can be used in a point of care setting and return diagnostic results within the timeframe of a visit to the general practitioner.

Public Mental Health

Author: William W. Eaton

Publisher: Oxford University Press

Published: 2019-04-03

Total Pages: 528

ISBN-13: 0190916621

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"[A] masterful volume that will do much to advance understanding of mental health as an essential public health challenge." -Journal of Sociology & Social Welfare THE GROUNDBREAKING TEXTBOOK IN POPULATION-LEVEL MENTAL HEALTH, NOW FULLY REVISED AND UPDATED Public Mental Health equips a new generation of public health students, researchers and practitioners with the most innovative social. biological, and behavioral science approaches to mental health challenges at the population level. Incorporating insights from multiple health and science disciplines, this new edition introduces novel concepts and methodologies for understanding the occurrence of mental disorders in populations worldwide. Reflecting the disciplinary diversity and expertise of an internationally-recognized roster of contributors, its nineteen chapters include coverage of such essential topics as: · estimates of global prevalence based on new data from the Global Burden of Disease Study · the complex way in which genes, other biological factors, and life stresses increase risk · mental health disparities among population subgroups · population-level mental health consequences of violence and natural disasters · the logic and practice of prevention of mental and behavioral disorders With a perspective that will resonate from the lab to the legislature floor, Public Mental Health offers a much-need core text for students, researchers, and practitioners.

Book Synopsis Public Mental Health by : William W. Eaton

Download or read book Public Mental Health written by William W. Eaton and published by Oxford University Press. This book was released on 2019-04-03 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: "[A] masterful volume that will do much to advance understanding of mental health as an essential public health challenge." -Journal of Sociology & Social Welfare THE GROUNDBREAKING TEXTBOOK IN POPULATION-LEVEL MENTAL HEALTH, NOW FULLY REVISED AND UPDATED Public Mental Health equips a new generation of public health students, researchers and practitioners with the most innovative social. biological, and behavioral science approaches to mental health challenges at the population level. Incorporating insights from multiple health and science disciplines, this new edition introduces novel concepts and methodologies for understanding the occurrence of mental disorders in populations worldwide. Reflecting the disciplinary diversity and expertise of an internationally-recognized roster of contributors, its nineteen chapters include coverage of such essential topics as: · estimates of global prevalence based on new data from the Global Burden of Disease Study · the complex way in which genes, other biological factors, and life stresses increase risk · mental health disparities among population subgroups · population-level mental health consequences of violence and natural disasters · the logic and practice of prevention of mental and behavioral disorders With a perspective that will resonate from the lab to the legislature floor, Public Mental Health offers a much-need core text for students, researchers, and practitioners.

Stem Cell Genetics for Biomedical Research

Author: Raul Delgado-Morales

Publisher: Springer

Published: 2018-06-27

Total Pages: 426

ISBN-13: 331990695X

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This book looks at where stem cell technology is presently and how it is instrumental in advancing the field of disease modeling and cell transplantation. By focusing on major human disorders such as Alzheimer’s disease, cancer, and heart disorders, the book summarizes the major findings in the field of human stem cells and dissect the current limitations on our understanding of stem cells biology. The chapters focus on the genetics, genomics, epigenetics and physiology of stem cells models, together with technological advances on molecular biology such as CRISPR/Cas9 or epigenetic editing, that will be instrumental in the future of human disease modeling and treatment. In base of the limitations of current disease models and in front of the unmet necessity of finding therapeutical interventions for human disorders, the availability of stem cell technology has opened new doors for several fields. The unlimited self-renewal capacity and more extensive differentiation potential of stem cells offers a theoretically inexhaustible and replenishable source of any cell subtype. Since Professor Shinya Yamanaka described it, 10 years ago in his seminal paper, that somatic cells could be reprogrammed to inducible stem cells (iPSC) just by expressing four transcription factors, the field of has exploded, especially its applications in biomedical research.

Book Synopsis Stem Cell Genetics for Biomedical Research by : Raul Delgado-Morales

Download or read book Stem Cell Genetics for Biomedical Research written by Raul Delgado-Morales and published by Springer. This book was released on 2018-06-27 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book looks at where stem cell technology is presently and how it is instrumental in advancing the field of disease modeling and cell transplantation. By focusing on major human disorders such as Alzheimer’s disease, cancer, and heart disorders, the book summarizes the major findings in the field of human stem cells and dissect the current limitations on our understanding of stem cells biology. The chapters focus on the genetics, genomics, epigenetics and physiology of stem cells models, together with technological advances on molecular biology such as CRISPR/Cas9 or epigenetic editing, that will be instrumental in the future of human disease modeling and treatment. In base of the limitations of current disease models and in front of the unmet necessity of finding therapeutical interventions for human disorders, the availability of stem cell technology has opened new doors for several fields. The unlimited self-renewal capacity and more extensive differentiation potential of stem cells offers a theoretically inexhaustible and replenishable source of any cell subtype. Since Professor Shinya Yamanaka described it, 10 years ago in his seminal paper, that somatic cells could be reprogrammed to inducible stem cells (iPSC) just by expressing four transcription factors, the field of has exploded, especially its applications in biomedical research.

Tauopathies—Advances in Research and Treatment: 2012 Edition

Author:

Publisher: ScholarlyEditions

Published: 2012-12-26

Total Pages: 713

ISBN-13: 1464991855

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Tauopathies—Advances in Research and Treatment: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Tauopathies. The editors have built Tauopathies—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Tauopathies in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Tauopathies—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Book Synopsis Tauopathies—Advances in Research and Treatment: 2012 Edition by :

Download or read book Tauopathies—Advances in Research and Treatment: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tauopathies—Advances in Research and Treatment: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Tauopathies. The editors have built Tauopathies—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Tauopathies in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Tauopathies—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Neuroproteomics as a Tool for Understanding Schizophrenia

Author: Daniel Martins-de-Souza

Publisher: Springer Nature

Published: 2022-08-05

Total Pages: 142

ISBN-13: 3030971821

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Over the past decade, neuroproteomics has shed light on the molecular features of schizophrenia by depicting biological processes involved with its establishment, maintenance and treatment. These studies have also pointed to potential biomarkers applicable to diagnosis and medication monitoring. Edited by a leader in the field of neuroproteomics with contributions from subject experts, this new volume will address recent findings and compile evidence from difference perspectives—such as human samples, animal models, pluripotent stem cell-derived in vitro pre-clinical models—and provide findings to inform the development of innovative future treatment strategies. This volume will be useful for a broad audience of researchers and professionals, including biologists, neurologists, psychiatrists, analytical chemists, and pharmacists, among others.

Book Synopsis Neuroproteomics as a Tool for Understanding Schizophrenia by : Daniel Martins-de-Souza

Download or read book Neuroproteomics as a Tool for Understanding Schizophrenia written by Daniel Martins-de-Souza and published by Springer Nature. This book was released on 2022-08-05 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, neuroproteomics has shed light on the molecular features of schizophrenia by depicting biological processes involved with its establishment, maintenance and treatment. These studies have also pointed to potential biomarkers applicable to diagnosis and medication monitoring. Edited by a leader in the field of neuroproteomics with contributions from subject experts, this new volume will address recent findings and compile evidence from difference perspectives—such as human samples, animal models, pluripotent stem cell-derived in vitro pre-clinical models—and provide findings to inform the development of innovative future treatment strategies. This volume will be useful for a broad audience of researchers and professionals, including biologists, neurologists, psychiatrists, analytical chemists, and pharmacists, among others.

Proteomics in Biomedicine and Pharmacology

Author:

Publisher: Academic Press

Published: 2014-07-03

Total Pages: 377

ISBN-13: 0128005955

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Volume 95 of Advances in Protein Chemistry and Structural Biology focuses on advances in proteomic techniques and their application in biomedicine and pharmacology. This volume describes in detail the applications of these techniques in studying a number of diseases and specific protein modifications and profiles, including phosphoproteomics, glycoproteomics, and more. Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series is the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics. Describes advances in application of powerful techniques in translational research (biomedicine and pharmacology) Chapters are written by authorities in their field Targeted to a wide audience of researchers, specialists, and students The information provided in the volume is well supported by a number of high quality illustrations, figures, and tables

Book Synopsis Proteomics in Biomedicine and Pharmacology by :

Download or read book Proteomics in Biomedicine and Pharmacology written by and published by Academic Press. This book was released on 2014-07-03 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 95 of Advances in Protein Chemistry and Structural Biology focuses on advances in proteomic techniques and their application in biomedicine and pharmacology. This volume describes in detail the applications of these techniques in studying a number of diseases and specific protein modifications and profiles, including phosphoproteomics, glycoproteomics, and more. Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series is the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics. Describes advances in application of powerful techniques in translational research (biomedicine and pharmacology) Chapters are written by authorities in their field Targeted to a wide audience of researchers, specialists, and students The information provided in the volume is well supported by a number of high quality illustrations, figures, and tables

Advances in Protein Chemistry and Structural Biology

Author:

Publisher: Academic Press

Published: 2014-03-11

Total Pages: 484

ISBN-13: 0128003731

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This eclectic volume features two major topics: applications of mass spectrometry in bioscience; and computational methods for analysis of protein structure and interactions with other macromolecules. Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series has been the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics. Describes advances in application of powerful techniques in a wide bioscience area Chapters are written by authorities in their field Targeted to a wide audience of researchers, specialists, and students The information provided in the volume is well supported by a number of high quality illustrations, figures, and tables

Book Synopsis Advances in Protein Chemistry and Structural Biology by :

Download or read book Advances in Protein Chemistry and Structural Biology written by and published by Academic Press. This book was released on 2014-03-11 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eclectic volume features two major topics: applications of mass spectrometry in bioscience; and computational methods for analysis of protein structure and interactions with other macromolecules. Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series has been the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics. Describes advances in application of powerful techniques in a wide bioscience area Chapters are written by authorities in their field Targeted to a wide audience of researchers, specialists, and students The information provided in the volume is well supported by a number of high quality illustrations, figures, and tables

Issues in Proteins and Peptides Research and Application: 2013 Edition

Author:

Publisher: ScholarlyEditions

Published: 2013-05-01

Total Pages: 1105

ISBN-13: 1490108009

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Issues in Proteins and Peptides Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Peptide Science. The editors have built Issues in Proteins and Peptides Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Peptide Science in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Proteins and Peptides Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Book Synopsis Issues in Proteins and Peptides Research and Application: 2013 Edition by :

Download or read book Issues in Proteins and Peptides Research and Application: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-05-01 with total page 1105 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Proteins and Peptides Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Peptide Science. The editors have built Issues in Proteins and Peptides Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Peptide Science in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Proteins and Peptides Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Neurobiology of Psychiatric Disorders

Author: Thomas E Schlaepfer

Publisher: Elsevier

Published: 2012-07-09

Total Pages: 781

ISBN-13: 0444520023

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This new volume in the Handbook of Clinical Neurology presents a comprehensive review of the fundamental science and clinical treatment of psychiatric disorders. Advances in neuroscience have allowed for dramatic advances in the understanding of psychiatric disorders and treatment. Brain disorders, such as depression and schizophrenia, are the leading cause of disability worldwide. It is estimated that over 25% of the adult population in North America are diagnosed yearly with at least one mental disorder and similar results hold for Europe. Now that neurology and psychiatry agree that all mental disorders are in fact, "brain diseases," this volume provides a foundational introduction to the science defining these disorders and details best practices for psychiatric treatment. Provides a comprehensive review of the scientific foundations of psychiatric disorders and psychiatric treatment Includes detailed results from genetics, molecular biology, brain imaging, and neuropathological, immunological, epidemiological, metabolic, therapeutic and historical aspects of the major psychiatric disorders A "must have" reference and resource for neuroscientists, neurologists, psychiatrists, and clinical psychologists as well as all research scientists investigating disorders of the brain

Book Synopsis Neurobiology of Psychiatric Disorders by : Thomas E Schlaepfer

Download or read book Neurobiology of Psychiatric Disorders written by Thomas E Schlaepfer and published by Elsevier. This book was released on 2012-07-09 with total page 781 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume in the Handbook of Clinical Neurology presents a comprehensive review of the fundamental science and clinical treatment of psychiatric disorders. Advances in neuroscience have allowed for dramatic advances in the understanding of psychiatric disorders and treatment. Brain disorders, such as depression and schizophrenia, are the leading cause of disability worldwide. It is estimated that over 25% of the adult population in North America are diagnosed yearly with at least one mental disorder and similar results hold for Europe. Now that neurology and psychiatry agree that all mental disorders are in fact, "brain diseases," this volume provides a foundational introduction to the science defining these disorders and details best practices for psychiatric treatment. Provides a comprehensive review of the scientific foundations of psychiatric disorders and psychiatric treatment Includes detailed results from genetics, molecular biology, brain imaging, and neuropathological, immunological, epidemiological, metabolic, therapeutic and historical aspects of the major psychiatric disorders A "must have" reference and resource for neuroscientists, neurologists, psychiatrists, and clinical psychologists as well as all research scientists investigating disorders of the brain

Recent Advances in Proteomics Research

Author: Sameh Magdeldin

Publisher: BoD – Books on Demand

Published: 2015-11-11

Total Pages: 168

ISBN-13: 9535122010

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Proteomics refers to the entire complement of proteins, including modification. This promising discipline has enabled us to study proteins from a massive and comprehensive point of view. The book Recent Advances in Proteomics Research describes in five sections some of the applications of proteomics. This fine research has been written by leading experts worldwide. This book is aimed mainly at those interested in proteins and in the field of proteins, particularly biochemists, biologists, pharmacists, advanced graduate students and postgraduate researchers.

Book Synopsis Recent Advances in Proteomics Research by : Sameh Magdeldin

Download or read book Recent Advances in Proteomics Research written by Sameh Magdeldin and published by BoD – Books on Demand. This book was released on 2015-11-11 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteomics refers to the entire complement of proteins, including modification. This promising discipline has enabled us to study proteins from a massive and comprehensive point of view. The book Recent Advances in Proteomics Research describes in five sections some of the applications of proteomics. This fine research has been written by leading experts worldwide. This book is aimed mainly at those interested in proteins and in the field of proteins, particularly biochemists, biologists, pharmacists, advanced graduate students and postgraduate researchers.