Modelling Protocells

Modelling Protocells

Author: Roberto Serra

Publisher: Springer

Published: 2017-07-24

Total Pages: 191

ISBN-13: 9402411607

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The monograph discusses models of synthetic protocells, which are cell-like structures obtained from non-living matter endowed with some rudimentary kind of metabolism and genetics, but much simpler than biological cells. They should grow and proliferate, generating offsprings that resemble in some way the parent protocells with some variation, so that selection may take place. Sustainable protocell populations have not yet been obtained experimentally and mathematical models are therefore extremely important to address key questions concerning their synthesis and behavior. Different protocell “architectures” have been proposed and high-level abstract models like those that are presented in this book are particularly relevant to gain a better understanding of the different properites. These models are able to treat all the major dynamical phenomena in a unified framework, so they can be seen as “virtual laboratories” for protocell research. Particular attention is paid to the problem of synchronization of the fission rate of the whole protocell and the duplication rate of its "protogenetic" material, which is shown to be an emergent property that spontaneously develops in successive generations. The book is of interest for a broad range of scientists working in soft matter physics, chemistry and biology, interested in the role protocells may play on the development of new technologies with medical, environmental and industrial applications as well as scientists interested in the origin of life.


Book Synopsis Modelling Protocells by : Roberto Serra

Download or read book Modelling Protocells written by Roberto Serra and published by Springer. This book was released on 2017-07-24 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: The monograph discusses models of synthetic protocells, which are cell-like structures obtained from non-living matter endowed with some rudimentary kind of metabolism and genetics, but much simpler than biological cells. They should grow and proliferate, generating offsprings that resemble in some way the parent protocells with some variation, so that selection may take place. Sustainable protocell populations have not yet been obtained experimentally and mathematical models are therefore extremely important to address key questions concerning their synthesis and behavior. Different protocell “architectures” have been proposed and high-level abstract models like those that are presented in this book are particularly relevant to gain a better understanding of the different properites. These models are able to treat all the major dynamical phenomena in a unified framework, so they can be seen as “virtual laboratories” for protocell research. Particular attention is paid to the problem of synchronization of the fission rate of the whole protocell and the duplication rate of its "protogenetic" material, which is shown to be an emergent property that spontaneously develops in successive generations. The book is of interest for a broad range of scientists working in soft matter physics, chemistry and biology, interested in the role protocells may play on the development of new technologies with medical, environmental and industrial applications as well as scientists interested in the origin of life.

The Ethics of Protocells

The Ethics of Protocells

Author: Gaymon Bennett

Publisher: MIT Press

Published: 2009

Total Pages: 381

ISBN-13: 0262012626

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Teams of scientists around the world are racing to create protocells--microscopic, self-organizing entities that spontaneously assemble from simple organic and inorganic materials. The creation of fully autonomous protocells--a technology that can, for all intents and purposes, be considered literally alive--is only a matter of time. This book examines the pressing social and ethical issues raised by the creation of life in the laboratory. Protocells might offer great medical and social benefits and vast new economic opportunities, but they also pose potential risks and threaten cultural and moral norms against tampering with nature and "playing God." The Ethics of Protocells offers a variety of perspectives on these concerns.


Book Synopsis The Ethics of Protocells by : Gaymon Bennett

Download or read book The Ethics of Protocells written by Gaymon Bennett and published by MIT Press. This book was released on 2009 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Teams of scientists around the world are racing to create protocells--microscopic, self-organizing entities that spontaneously assemble from simple organic and inorganic materials. The creation of fully autonomous protocells--a technology that can, for all intents and purposes, be considered literally alive--is only a matter of time. This book examines the pressing social and ethical issues raised by the creation of life in the laboratory. Protocells might offer great medical and social benefits and vast new economic opportunities, but they also pose potential risks and threaten cultural and moral norms against tampering with nature and "playing God." The Ethics of Protocells offers a variety of perspectives on these concerns.

Protocell Architecture

Protocell Architecture

Author: Neil Spiller

Publisher: John Wiley & Sons

Published: 2011-04-18

Total Pages: 147

ISBN-13: 0470748281

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Throughout the ages architects have attempted to capture the essence of living systems as design inspiration. However, practitioners of the built environment have had to deal with a fundamental split between the artificial urban landscape and nature owing to a technological 'gap' that means architects have been unable to make effective use of biological systems in urban environments. Protocell Architecture is an edition of AD that shows for the first time that contemporary architects can create and construct architectures that are bottom up, synthetically biological, green and have no recourse to shallow bio-mimicry. In the next few decades, synthetic biology is set to have as much, if not more, impact on architecture as cyberspace and the digital. The key to these amazing architectural innovations is the Protocell.


Book Synopsis Protocell Architecture by : Neil Spiller

Download or read book Protocell Architecture written by Neil Spiller and published by John Wiley & Sons. This book was released on 2011-04-18 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout the ages architects have attempted to capture the essence of living systems as design inspiration. However, practitioners of the built environment have had to deal with a fundamental split between the artificial urban landscape and nature owing to a technological 'gap' that means architects have been unable to make effective use of biological systems in urban environments. Protocell Architecture is an edition of AD that shows for the first time that contemporary architects can create and construct architectures that are bottom up, synthetically biological, green and have no recourse to shallow bio-mimicry. In the next few decades, synthetic biology is set to have as much, if not more, impact on architecture as cyberspace and the digital. The key to these amazing architectural innovations is the Protocell.

Protocells

Protocells

Author: Steen Rasmussen

Publisher: MIT Press

Published: 2022-06-07

Total Pages: 723

ISBN-13: 0262545888

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The first comprehensive general resource on state-of-the-art protocell research, describing current approaches to making new forms of life from scratch in the laboratory. Protocells offers a comprehensive resource on current attempts to create simple forms of life from scratch in the laboratory. These minimal versions of cells, known as protocells, are entities with lifelike properties created from nonliving materials, and the book provides in-depth investigations of processes at the interface between nonliving and living matter. Chapters by experts in the field put this state-of-the-art research in the context of theory, laboratory work, and computer simulations on the components and properties of protocells. The book also provides perspectives on research in related areas and such broader societal issues as commercial applications and ethical considerations. The book covers all major scientific approaches to creating minimal life, both in the laboratory and in simulation. It emphasizes the bottom-up view of physicists, chemists, and material scientists but also includes the molecular biologists' top-down approach and the origin-of-life perspective. The capacity to engineer living technology could have an enormous socioeconomic impact and could bring both good and ill. Protocells promises to be the essential reference for research on bottom-up assembly of life and living technology for years to come. It is written to be both resource and inspiration for scientists working in this exciting and important field and a definitive text for the interested layman.


Book Synopsis Protocells by : Steen Rasmussen

Download or read book Protocells written by Steen Rasmussen and published by MIT Press. This book was released on 2022-06-07 with total page 723 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive general resource on state-of-the-art protocell research, describing current approaches to making new forms of life from scratch in the laboratory. Protocells offers a comprehensive resource on current attempts to create simple forms of life from scratch in the laboratory. These minimal versions of cells, known as protocells, are entities with lifelike properties created from nonliving materials, and the book provides in-depth investigations of processes at the interface between nonliving and living matter. Chapters by experts in the field put this state-of-the-art research in the context of theory, laboratory work, and computer simulations on the components and properties of protocells. The book also provides perspectives on research in related areas and such broader societal issues as commercial applications and ethical considerations. The book covers all major scientific approaches to creating minimal life, both in the laboratory and in simulation. It emphasizes the bottom-up view of physicists, chemists, and material scientists but also includes the molecular biologists' top-down approach and the origin-of-life perspective. The capacity to engineer living technology could have an enormous socioeconomic impact and could bring both good and ill. Protocells promises to be the essential reference for research on bottom-up assembly of life and living technology for years to come. It is written to be both resource and inspiration for scientists working in this exciting and important field and a definitive text for the interested layman.

Encyclopedia of Astrobiology

Encyclopedia of Astrobiology

Author: Ricardo Amils

Publisher: Springer

Published: 2021-01-14

Total Pages: 1853

ISBN-13: 9783642278334

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The interdisciplinary field of Astrobiology constitutes a joint arena where provocative discoveries are coalescing concerning, e.g. the prevalence of exoplanets, the diversity and hardiness of life, and its increasingly likely chances for its emergence. Biologists, astrophysicists, biochemists, geoscientists and space scientists share this exciting mission of revealing the origin and commonality of life in the Universe. The members of the different disciplines are used to their own terminology and technical language. In the interdisciplinary environment many terms either have redundant meanings or are completely unfamiliar to members of other disciplines. The Encyclopedia of Astrobiology serves as the key to a common understanding. Each new or experienced researcher and graduate student in adjacent fields of astrobiology will appreciate this reference work in the quest to understand the big picture. The carefully selected group of active researchers contributing to this work and the expert field editors intend for their contributions, from an internationally comprehensive perspective, to accelerate the interdisciplinary advance of astrobiology.


Book Synopsis Encyclopedia of Astrobiology by : Ricardo Amils

Download or read book Encyclopedia of Astrobiology written by Ricardo Amils and published by Springer. This book was released on 2021-01-14 with total page 1853 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interdisciplinary field of Astrobiology constitutes a joint arena where provocative discoveries are coalescing concerning, e.g. the prevalence of exoplanets, the diversity and hardiness of life, and its increasingly likely chances for its emergence. Biologists, astrophysicists, biochemists, geoscientists and space scientists share this exciting mission of revealing the origin and commonality of life in the Universe. The members of the different disciplines are used to their own terminology and technical language. In the interdisciplinary environment many terms either have redundant meanings or are completely unfamiliar to members of other disciplines. The Encyclopedia of Astrobiology serves as the key to a common understanding. Each new or experienced researcher and graduate student in adjacent fields of astrobiology will appreciate this reference work in the quest to understand the big picture. The carefully selected group of active researchers contributing to this work and the expert field editors intend for their contributions, from an internationally comprehensive perspective, to accelerate the interdisciplinary advance of astrobiology.

Beginnings of Cellular Life

Beginnings of Cellular Life

Author: Harold J. Morowitz

Publisher: Yale University Press

Published: 1993-01-01

Total Pages: 212

ISBN-13: 9780300102109

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Develops a model of the origin of life in which cells originate first, proteins follow, and genes evolve last, which is supported by evidence mustered from biology, biochemistry, and biophysics. This work explores the origins of life and is for anyone who has ever thought seriously about the origin of life.


Book Synopsis Beginnings of Cellular Life by : Harold J. Morowitz

Download or read book Beginnings of Cellular Life written by Harold J. Morowitz and published by Yale University Press. This book was released on 1993-01-01 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Develops a model of the origin of life in which cells originate first, proteins follow, and genes evolve last, which is supported by evidence mustered from biology, biochemistry, and biophysics. This work explores the origins of life and is for anyone who has ever thought seriously about the origin of life.

The Ethics of Protocells

The Ethics of Protocells

Author: Mark A. Bedau

Publisher: MIT Press

Published: 2009-04-17

Total Pages: 381

ISBN-13: 0262292297

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Experts explore the potential benefits, risks, and moral aspects of protocell technology, which creates simple forms of life from nonliving material. Teams of scientists around the world are racing to create protocells—microscopic, self-organizing entities that spontaneously assemble from simple organic and inorganic materials. The creation of fully autonomous protocells—a technology that can, for all intents and purposes, be considered literally alive—is only a matter of time. This book examines the pressing social and ethical issues raised by the creation of life in the laboratory. Protocells might offer great medical and social benefits and vast new economic opportunities, but they also pose potential risks and threaten cultural and moral norms against tampering with nature and “playing God.” The Ethics of Protocells offers a variety of perspectives on these concerns. After a brief survey of current protocell research (including the much-publicized “top-down” strategy of J. Craig Venter and Hamilton Smith, for which they have received multimillion dollar financing from the U.S. Department of Energy), the chapters treat risk, uncertainty, and precaution; lessons from recent history and related technologies; and ethics in a future society with protocells. The discussions range from new considerations of the precautionary principle and the role of professional ethicists to explorations of what can be learned from society's experience with other biotechnologies and the open-source software movement. Contributors Mark A. Bedau, Gaymon Bennett, Giovanni Boniolo, Carl Cranor, Bill Durodié, Mickey Gjerris, Brigitte Hantsche-Tangen, Christine Hauskeller, Andrew Hessel, Brian Johnson, George Khushf, Emily C. Parke, Alain Pottage, Paul Rabinow, Per Sandin, Joachim Schummer, Mark Triant, Laurie Zoloth


Book Synopsis The Ethics of Protocells by : Mark A. Bedau

Download or read book The Ethics of Protocells written by Mark A. Bedau and published by MIT Press. This book was released on 2009-04-17 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experts explore the potential benefits, risks, and moral aspects of protocell technology, which creates simple forms of life from nonliving material. Teams of scientists around the world are racing to create protocells—microscopic, self-organizing entities that spontaneously assemble from simple organic and inorganic materials. The creation of fully autonomous protocells—a technology that can, for all intents and purposes, be considered literally alive—is only a matter of time. This book examines the pressing social and ethical issues raised by the creation of life in the laboratory. Protocells might offer great medical and social benefits and vast new economic opportunities, but they also pose potential risks and threaten cultural and moral norms against tampering with nature and “playing God.” The Ethics of Protocells offers a variety of perspectives on these concerns. After a brief survey of current protocell research (including the much-publicized “top-down” strategy of J. Craig Venter and Hamilton Smith, for which they have received multimillion dollar financing from the U.S. Department of Energy), the chapters treat risk, uncertainty, and precaution; lessons from recent history and related technologies; and ethics in a future society with protocells. The discussions range from new considerations of the precautionary principle and the role of professional ethicists to explorations of what can be learned from society's experience with other biotechnologies and the open-source software movement. Contributors Mark A. Bedau, Gaymon Bennett, Giovanni Boniolo, Carl Cranor, Bill Durodié, Mickey Gjerris, Brigitte Hantsche-Tangen, Christine Hauskeller, Andrew Hessel, Brian Johnson, George Khushf, Emily C. Parke, Alain Pottage, Paul Rabinow, Per Sandin, Joachim Schummer, Mark Triant, Laurie Zoloth

Origin of Life

Origin of Life

Author: David W. Deamer

Publisher: Oxford University Press

Published: 2020-08-01

Total Pages: 160

ISBN-13: 019009902X

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It seems likely that scientists will someday discover how life can emerge on habitable planets like the early Earth and Mars. In Origin of Life: What Everyone Needs to Know®, David W. Deamer has written a comprehensive guide to the origin of life that is organized in three sections. The first section addresses questions such as: Where do the atoms of life come from? How old is Earth? What was the Earth like before life began? Where does water come from? After each question is answered, there is a follow-up: How do we know? This expands the horizon of the book, explaining how scientists reach conclusions and why we can trust these answers. The second section describes how certain organic molecules can spontaneously assemble into populations of protocells that can undergo selection and evolve toward primitive living systems. Here Deamer proposes a truly novel concept that life did not begin in the ocean but instead in fresh water hot springs on volcanic land masses resembling Hawaii today. True knowledge is not just what we know, but equally important is what we don't yet know. In the third section Deamer lists the outstanding questions that must be addressed before we can finally answer a fundamental question of biology: How can life begin?


Book Synopsis Origin of Life by : David W. Deamer

Download or read book Origin of Life written by David W. Deamer and published by Oxford University Press. This book was released on 2020-08-01 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: It seems likely that scientists will someday discover how life can emerge on habitable planets like the early Earth and Mars. In Origin of Life: What Everyone Needs to Know®, David W. Deamer has written a comprehensive guide to the origin of life that is organized in three sections. The first section addresses questions such as: Where do the atoms of life come from? How old is Earth? What was the Earth like before life began? Where does water come from? After each question is answered, there is a follow-up: How do we know? This expands the horizon of the book, explaining how scientists reach conclusions and why we can trust these answers. The second section describes how certain organic molecules can spontaneously assemble into populations of protocells that can undergo selection and evolve toward primitive living systems. Here Deamer proposes a truly novel concept that life did not begin in the ocean but instead in fresh water hot springs on volcanic land masses resembling Hawaii today. True knowledge is not just what we know, but equally important is what we don't yet know. In the third section Deamer lists the outstanding questions that must be addressed before we can finally answer a fundamental question of biology: How can life begin?

Synthetic Aesthetics

Synthetic Aesthetics

Author: Alexandra Daisy Ginsberg

Publisher: MIT Press

Published: 2014-02-28

Total Pages: 372

ISBN-13: 026201999X

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As synthetic biology transforms living matter into a medium for making, what is the role of design and its associated values?


Book Synopsis Synthetic Aesthetics by : Alexandra Daisy Ginsberg

Download or read book Synthetic Aesthetics written by Alexandra Daisy Ginsberg and published by MIT Press. This book was released on 2014-02-28 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: As synthetic biology transforms living matter into a medium for making, what is the role of design and its associated values?

Prebiotic Chemistry

Prebiotic Chemistry

Author: Peter Walde

Publisher: Springer

Published: 2010-02-12

Total Pages: 0

ISBN-13: 9783642066146

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D.W. Deamer, J.P. Dworkin: Chemistry and Physics of Primitive Membranes.- R.Saladino, C. Crestini, G. Costanzo, E. DiMauro: On the Prebiotic Synthesis of Nucleobases, Nucleotides, Oligonucleotides, Pre-RNA and Pre-DNA Molecules.- R. Pascal, L. Boiteau, A. Commeyras: From the Prebiotic Synthesis of alpha-Amino Acids Towards a Primitive Translation Apparatus for the Synthesis of Peptides.- I. Weissbuch, L: Leiserowitz, M. Lahav: Stochastic "Mirror-Symmetry Breaking" via Self-Assembly, Reactivity and Amplification of Chirality: Relevance to Abiotic Conditions.- E. Szathmáry, M.Santos, C. Fernando: Evolutionary Potential and Requirements for Minimal Protocells


Book Synopsis Prebiotic Chemistry by : Peter Walde

Download or read book Prebiotic Chemistry written by Peter Walde and published by Springer. This book was released on 2010-02-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: D.W. Deamer, J.P. Dworkin: Chemistry and Physics of Primitive Membranes.- R.Saladino, C. Crestini, G. Costanzo, E. DiMauro: On the Prebiotic Synthesis of Nucleobases, Nucleotides, Oligonucleotides, Pre-RNA and Pre-DNA Molecules.- R. Pascal, L. Boiteau, A. Commeyras: From the Prebiotic Synthesis of alpha-Amino Acids Towards a Primitive Translation Apparatus for the Synthesis of Peptides.- I. Weissbuch, L: Leiserowitz, M. Lahav: Stochastic "Mirror-Symmetry Breaking" via Self-Assembly, Reactivity and Amplification of Chirality: Relevance to Abiotic Conditions.- E. Szathmáry, M.Santos, C. Fernando: Evolutionary Potential and Requirements for Minimal Protocells