Radiobiology of Large Animals

Radiobiology of Large Animals

Author: John S. Krebs

Publisher:

Published: 1975

Total Pages: 184

ISBN-13:

DOWNLOAD EBOOK

;Contents: Lethality in sheep exposed to 60CO gamma radiation using various exposure parameters; Hematological findings in sheep exposed to lethal levels of 60CO gamma rays at various dose rates and under various conditions of exposure; Cellular changes in bone marrow of mice and sheep during and after exposure to 60CO gamma rays; Biological and mathematical analysis of lethality in large animals exposed to ionizing radiation.


Book Synopsis Radiobiology of Large Animals by : John S. Krebs

Download or read book Radiobiology of Large Animals written by John S. Krebs and published by . This book was released on 1975 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: ;Contents: Lethality in sheep exposed to 60CO gamma radiation using various exposure parameters; Hematological findings in sheep exposed to lethal levels of 60CO gamma rays at various dose rates and under various conditions of exposure; Cellular changes in bone marrow of mice and sheep during and after exposure to 60CO gamma rays; Biological and mathematical analysis of lethality in large animals exposed to ionizing radiation.


Radiobiology of Large Animals

Radiobiology of Large Animals

Author: David C. L. Jones

Publisher:

Published: 1970

Total Pages: 47

ISBN-13:

DOWNLOAD EBOOK

Significant accumulation of radiation injury in sheep continuously irradiated (Cobalt 60) at dose rates of less than 1 R/hr has been demonstrated. The estimated LD50/60 at 0.91 R/hr is 1277 R, while the amount of residual injury after an accumulated exposure of 727 R at 0.46 R/hr is indicative of an LD50/60 of 1957 R. Increasing the dose rate to 3.4 R/hr, with simultaneous reduction in exposure time so that incremental weekly doses (140 R) remain the same as at 0.91 R/hr, results in a significant lowering of the estimated LD50/60 to 1054 R. Combined analysis of previous results from a kinetic standpoint indicates that counts of circulating leucocytes in the sheep are not primarily determined by the size of the parent stemcell population. In addition, it has been found that hematologic measures in the sheep tend to show marked departures from the normal distribution. Finally, radioactive tracer studies have shown that the total bone-marrow cellularity per kilogram of body weight is similar in mice and in sheep. (Author).


Book Synopsis Radiobiology of Large Animals by : David C. L. Jones

Download or read book Radiobiology of Large Animals written by David C. L. Jones and published by . This book was released on 1970 with total page 47 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant accumulation of radiation injury in sheep continuously irradiated (Cobalt 60) at dose rates of less than 1 R/hr has been demonstrated. The estimated LD50/60 at 0.91 R/hr is 1277 R, while the amount of residual injury after an accumulated exposure of 727 R at 0.46 R/hr is indicative of an LD50/60 of 1957 R. Increasing the dose rate to 3.4 R/hr, with simultaneous reduction in exposure time so that incremental weekly doses (140 R) remain the same as at 0.91 R/hr, results in a significant lowering of the estimated LD50/60 to 1054 R. Combined analysis of previous results from a kinetic standpoint indicates that counts of circulating leucocytes in the sheep are not primarily determined by the size of the parent stemcell population. In addition, it has been found that hematologic measures in the sheep tend to show marked departures from the normal distribution. Finally, radioactive tracer studies have shown that the total bone-marrow cellularity per kilogram of body weight is similar in mice and in sheep. (Author).


Low-Dose Radiation Effects on Animals and Ecosystems

Low-Dose Radiation Effects on Animals and Ecosystems

Author: Manabu Fukumoto

Publisher: Springer Nature

Published: 2019-11-14

Total Pages: 259

ISBN-13: 9811382182

DOWNLOAD EBOOK

This open access book summarizes the latest scientific findings regarding the biological effects of the Fukushima Daiichi Nuclear Power Plant (FNPP) accident in 2011. Various cases of changes in animals and organisms have been reported since the FNPP accident. However, it is often unknown whether they are actually due to radiation, since the dose or dose-rate are not necessarily associated with the changes observed. This book brings together the works of radiation biologists and ecologists to provide reliable radioecology data and gives insight into future radioprotection. The book examines the environmental pollution and radiation exposure, and contains valuable data from abandoned livestock in the ex-evacuation zone and from wild animals including invertebrates and vertebrates, aqueous and terrestrial animals, and plants that are subjected to long-term exposure in the area still affected by radiation. It also analyzes dose evaluation, and offers new perspectives gained from the accident, as well as an overview for future studies to promote radioprotection of humans and the ecosystem. Since the biological impact of radiation is influenced by various factors, it is difficult to scientifically define the effects of low-dose/low-dose-rate radiation. However, the detailed research data presented can be combined with the latest scientific and technological advances, such as artificial intelligence, to provide new insights in the future. This book is a unique and valuable resource for researchers, professionals and anyone interested in the impact of exposure to radiation or contamination with radioactive materials.


Book Synopsis Low-Dose Radiation Effects on Animals and Ecosystems by : Manabu Fukumoto

Download or read book Low-Dose Radiation Effects on Animals and Ecosystems written by Manabu Fukumoto and published by Springer Nature. This book was released on 2019-11-14 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book summarizes the latest scientific findings regarding the biological effects of the Fukushima Daiichi Nuclear Power Plant (FNPP) accident in 2011. Various cases of changes in animals and organisms have been reported since the FNPP accident. However, it is often unknown whether they are actually due to radiation, since the dose or dose-rate are not necessarily associated with the changes observed. This book brings together the works of radiation biologists and ecologists to provide reliable radioecology data and gives insight into future radioprotection. The book examines the environmental pollution and radiation exposure, and contains valuable data from abandoned livestock in the ex-evacuation zone and from wild animals including invertebrates and vertebrates, aqueous and terrestrial animals, and plants that are subjected to long-term exposure in the area still affected by radiation. It also analyzes dose evaluation, and offers new perspectives gained from the accident, as well as an overview for future studies to promote radioprotection of humans and the ecosystem. Since the biological impact of radiation is influenced by various factors, it is difficult to scientifically define the effects of low-dose/low-dose-rate radiation. However, the detailed research data presented can be combined with the latest scientific and technological advances, such as artificial intelligence, to provide new insights in the future. This book is a unique and valuable resource for researchers, professionals and anyone interested in the impact of exposure to radiation or contamination with radioactive materials.


Radiobiology of Humans and Animals

Radiobiology of Humans and Animals

Author: S. P. Yarmonenko

Publisher:

Published: 1988

Total Pages: 398

ISBN-13: 9785030000626

DOWNLOAD EBOOK


Book Synopsis Radiobiology of Humans and Animals by : S. P. Yarmonenko

Download or read book Radiobiology of Humans and Animals written by S. P. Yarmonenko and published by . This book was released on 1988 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt:


The Radiobiology and Radioecology of Farm Animals

The Radiobiology and Radioecology of Farm Animals

Author: Boris Nikolaevich Annenkov

Publisher:

Published: 1974

Total Pages: 236

ISBN-13:

DOWNLOAD EBOOK


Book Synopsis The Radiobiology and Radioecology of Farm Animals by : Boris Nikolaevich Annenkov

Download or read book The Radiobiology and Radioecology of Farm Animals written by Boris Nikolaevich Annenkov and published by . This book was released on 1974 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Health Effects of Exposure to Low Levels of Ionizing Radiation

Health Effects of Exposure to Low Levels of Ionizing Radiation

Author: National Research Council

Publisher: National Academies

Published: 1990-02-01

Total Pages: 436

ISBN-13: 0309039959

DOWNLOAD EBOOK

This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.


Book Synopsis Health Effects of Exposure to Low Levels of Ionizing Radiation by : National Research Council

Download or read book Health Effects of Exposure to Low Levels of Ionizing Radiation written by National Research Council and published by National Academies. This book was released on 1990-02-01 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.


Adverse Reproductive Outcomes in Families of Atomic Veterans

Adverse Reproductive Outcomes in Families of Atomic Veterans

Author: Institute of Medicine

Publisher: National Academies Press

Published: 1995-07-17

Total Pages: 107

ISBN-13: 0309176115

DOWNLOAD EBOOK

Over the past several decades, public concern over exposure to ionizing radiation has increased. This concern has manifested itself in different ways depending on the perception of risk to different individuals and different groups and the circumstances of their exposure. One such group are those U.S. servicemen (the "Atomic Veterans" who participated in the atmospheric testing of nuclear weapons at the Nevada Test Site or in the Pacific Proving Grounds, who served with occupation forces in or near Hiroshima and Nagasaki, or who were prisoners of war in or near those cities at the time of, or shortly after, the atomic bombings. This book addresses the feasibility of conducting an epidemiologic study to determine if there is an increased risk of adverse reproductive outcomes in the spouses, children, and grandchildren of the Atomic Veterans.


Book Synopsis Adverse Reproductive Outcomes in Families of Atomic Veterans by : Institute of Medicine

Download or read book Adverse Reproductive Outcomes in Families of Atomic Veterans written by Institute of Medicine and published by National Academies Press. This book was released on 1995-07-17 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past several decades, public concern over exposure to ionizing radiation has increased. This concern has manifested itself in different ways depending on the perception of risk to different individuals and different groups and the circumstances of their exposure. One such group are those U.S. servicemen (the "Atomic Veterans" who participated in the atmospheric testing of nuclear weapons at the Nevada Test Site or in the Pacific Proving Grounds, who served with occupation forces in or near Hiroshima and Nagasaki, or who were prisoners of war in or near those cities at the time of, or shortly after, the atomic bombings. This book addresses the feasibility of conducting an epidemiologic study to determine if there is an increased risk of adverse reproductive outcomes in the spouses, children, and grandchildren of the Atomic Veterans.


Holland-Frei Cancer Medicine

Holland-Frei Cancer Medicine

Author: Robert C. Bast, Jr.

Publisher: John Wiley & Sons

Published: 2017-03-10

Total Pages: 2008

ISBN-13: 111900084X

DOWNLOAD EBOOK

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates


Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.

Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2008 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates


Response of Different Species to Total Body Irradiation

Response of Different Species to Total Body Irradiation

Author: J.J. Broerse

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 233

ISBN-13: 9400960484

DOWNLOAD EBOOK

J.J. Broerse, Radiobiological Institute TNO, Rijswijk, The Netherlands, and T .J. MacVittie, Armed Forces Radiobiology Research Institute, Bethesda, MD, USA. During the past decade, relatively few new studies have been initiated on the response of different species to high-dose, total-body irradia tion. For information on the LDSO/30d (the dose which produces 50 percent lethality within 30 days), one is generally referred to the older literature (e. g., Bond, Fliedner and Archambeau, 1965). Compari son of experimental data reveals considerable variations in LDSD values even after total-body irradiation with conventional X rays, ranging from 4 to 6 Gy in the monkey, 7.1 to 9 Gy in the rat and from 6.4 to 9 Gy in the mouse (see also Hall, 1978). Part of the discrepancy in the LDso values can possibly be attributed to inadequacies in the dosimetry procedures and exposure arrangements employed. As far as clinical experience is concerned, there is now an appreciable amount of information available about the effect of total body irradiation as a conditioning treatment for bone marrow transplan tation in patients suffering from leukaemia or aplastic anaemia. The results from different centres, including the incidence of complications such as radiation pneumonitis, are considerably different. This can part I y be connected with the application of different radiation sched ules: large single dose versus fractionated or protracted irradiation.


Book Synopsis Response of Different Species to Total Body Irradiation by : J.J. Broerse

Download or read book Response of Different Species to Total Body Irradiation written by J.J. Broerse and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: J.J. Broerse, Radiobiological Institute TNO, Rijswijk, The Netherlands, and T .J. MacVittie, Armed Forces Radiobiology Research Institute, Bethesda, MD, USA. During the past decade, relatively few new studies have been initiated on the response of different species to high-dose, total-body irradia tion. For information on the LDSO/30d (the dose which produces 50 percent lethality within 30 days), one is generally referred to the older literature (e. g., Bond, Fliedner and Archambeau, 1965). Compari son of experimental data reveals considerable variations in LDSD values even after total-body irradiation with conventional X rays, ranging from 4 to 6 Gy in the monkey, 7.1 to 9 Gy in the rat and from 6.4 to 9 Gy in the mouse (see also Hall, 1978). Part of the discrepancy in the LDso values can possibly be attributed to inadequacies in the dosimetry procedures and exposure arrangements employed. As far as clinical experience is concerned, there is now an appreciable amount of information available about the effect of total body irradiation as a conditioning treatment for bone marrow transplan tation in patients suffering from leukaemia or aplastic anaemia. The results from different centres, including the incidence of complications such as radiation pneumonitis, are considerably different. This can part I y be connected with the application of different radiation sched ules: large single dose versus fractionated or protracted irradiation.


Health Risks of Radon and Other Internally Deposited Alpha-Emitters

Health Risks of Radon and Other Internally Deposited Alpha-Emitters

Author: National Research Council

Publisher: National Academies Press

Published: 1988-02-01

Total Pages: 623

ISBN-13: 0309037891

DOWNLOAD EBOOK

This book describes hazards from radon progeny and other alpha-emitters that humans may inhale or ingest from their environment. In their analysis, the authors summarize in one document clinical and epidemiological evidence, the results of animal studies, research on alpha-particle damage at the cellular level, metabolic pathways for internal alpha-emitters, dosimetry and microdosimetry of radionuclides deposited in specific tissues, and the chemical toxicity of some low-specific-activity alpha-emitters. Techniques for estimating the risks to humans posed by radon and other internally deposited alpha-emitters are offered, along with a discussion of formulas, models, methods, and the level of uncertainty inherent in the risk estimates.


Book Synopsis Health Risks of Radon and Other Internally Deposited Alpha-Emitters by : National Research Council

Download or read book Health Risks of Radon and Other Internally Deposited Alpha-Emitters written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes hazards from radon progeny and other alpha-emitters that humans may inhale or ingest from their environment. In their analysis, the authors summarize in one document clinical and epidemiological evidence, the results of animal studies, research on alpha-particle damage at the cellular level, metabolic pathways for internal alpha-emitters, dosimetry and microdosimetry of radionuclides deposited in specific tissues, and the chemical toxicity of some low-specific-activity alpha-emitters. Techniques for estimating the risks to humans posed by radon and other internally deposited alpha-emitters are offered, along with a discussion of formulas, models, methods, and the level of uncertainty inherent in the risk estimates.