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Robotic Cell Manipulation

Author: Dong Sun

Publisher: Academic Press

Published: 2022-05-31

Total Pages: 548

ISBN-13: 0323852602

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Robotic Cell Manipulation introduces up-to-date research to realize this new theme of medical robotics. The book is organized in three levels: operation tools (e.g., optical tweezers, microneedles, dielectrophoresis, electromagnetic devices, and microfluidic chips), manipulation types (e.g., microinjection, transportation, rotation fusion, adhesion, separation, etc.), and potential medical applications (e.g., micro-surgery, biopsy, gene editing, cancer treatment, cell-cell interactions, etc.). The technology involves different fields such as robotics, automation, imaging, microfluidics, mechanics, materials, biology and medical sciences. The book provides systematic knowledge on the subject, covering a wide range of basic concepts, theories, methodology, experiments, case studies and potential medical applications. It will enable readers to promptly conduct a systematic review of research and become an essential reference for many new and experienced researchers entering this unique field. Introduces the applications of robot-assisted manipulation tools in various cell manipulation tasks Defines many essential concepts in association with the robotic cell manipulation field, including manipulation strategy and manipulation types Introduces basic concepts and knowledge on various manipulation devices and tasks Describes some cutting-edge cell manipulation technologies and case studies

Book Synopsis Robotic Cell Manipulation by : Dong Sun

Download or read book Robotic Cell Manipulation written by Dong Sun and published by Academic Press. This book was released on 2022-05-31 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Robotic Cell Manipulation introduces up-to-date research to realize this new theme of medical robotics. The book is organized in three levels: operation tools (e.g., optical tweezers, microneedles, dielectrophoresis, electromagnetic devices, and microfluidic chips), manipulation types (e.g., microinjection, transportation, rotation fusion, adhesion, separation, etc.), and potential medical applications (e.g., micro-surgery, biopsy, gene editing, cancer treatment, cell-cell interactions, etc.). The technology involves different fields such as robotics, automation, imaging, microfluidics, mechanics, materials, biology and medical sciences. The book provides systematic knowledge on the subject, covering a wide range of basic concepts, theories, methodology, experiments, case studies and potential medical applications. It will enable readers to promptly conduct a systematic review of research and become an essential reference for many new and experienced researchers entering this unique field. Introduces the applications of robot-assisted manipulation tools in various cell manipulation tasks Defines many essential concepts in association with the robotic cell manipulation field, including manipulation strategy and manipulation types Introduces basic concepts and knowledge on various manipulation devices and tasks Describes some cutting-edge cell manipulation technologies and case studies

Robotics for Cell Manipulation and Characterization

Author: Changsheng Dai

Publisher: Elsevier

Published: 2023-04-20

Total Pages: 402

ISBN-13: 0323952143

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Robotics for Cell Manipulation and Characterization provides fundamental principles underpinning robotic cell manipulation and characterization, state-of-the-art technical advances in micro/nano robotics, new discoveries of cell biology enabled by robotic systems, and their applications in clinical diagnosis and treatment. This book covers several areas, including robotics, control, computer vision, biomedical engineering and life sciences using understandable figures and tables to enhance readers’ comprehension and pinpoint challenges and opportunities for biological and biomedical research. Focuses on, and comprehensively covers, robotics for cell manipulation and characterization Highlights recent advances in cell biology and disease treatment enabled by robotic cell manipulation and characterization Provides insightful outlooks on future challenges and opportunities

Book Synopsis Robotics for Cell Manipulation and Characterization by : Changsheng Dai

Download or read book Robotics for Cell Manipulation and Characterization written by Changsheng Dai and published by Elsevier. This book was released on 2023-04-20 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Robotics for Cell Manipulation and Characterization provides fundamental principles underpinning robotic cell manipulation and characterization, state-of-the-art technical advances in micro/nano robotics, new discoveries of cell biology enabled by robotic systems, and their applications in clinical diagnosis and treatment. This book covers several areas, including robotics, control, computer vision, biomedical engineering and life sciences using understandable figures and tables to enhance readers’ comprehension and pinpoint challenges and opportunities for biological and biomedical research. Focuses on, and comprehensively covers, robotics for cell manipulation and characterization Highlights recent advances in cell biology and disease treatment enabled by robotic cell manipulation and characterization Provides insightful outlooks on future challenges and opportunities

Robotic Manipulation of Reproductive Cells

Author: Changsheng Dai

Publisher: Springer

Published: 2024-03-09

Total Pages: 0

ISBN-13: 9783031527296

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This is the first book to focus on robotic reproductive cell manipulation. It provides readers with the fundamental principles underpinning robotic manipulation of reproductive cells, including sperm, oocytes, and embryos, state-of-the-art technical advances in actuation, sensing and control for cell manipulation, and emerging automated systems for reproductive cell manipulation. The methods presented in the book are generic and can be translated to manipulating other types of cells, such as cancer cells and cardiomyocytes. Robotic Manipulation of Reproductive Cells will be an essential reference for graduate students and researchers working on small-scale robotic systems for cell manipulation and characterization, healthcare professionals interested in nanoscale, microscale, milli-scale robotic techniques for clinical cell surgeries and assisted reproduction, and engineers developing small-scale robotic systems for biomedical engineering, biology, and medicine.

Book Synopsis Robotic Manipulation of Reproductive Cells by : Changsheng Dai

Download or read book Robotic Manipulation of Reproductive Cells written by Changsheng Dai and published by Springer. This book was released on 2024-03-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to focus on robotic reproductive cell manipulation. It provides readers with the fundamental principles underpinning robotic manipulation of reproductive cells, including sperm, oocytes, and embryos, state-of-the-art technical advances in actuation, sensing and control for cell manipulation, and emerging automated systems for reproductive cell manipulation. The methods presented in the book are generic and can be translated to manipulating other types of cells, such as cancer cells and cardiomyocytes. Robotic Manipulation of Reproductive Cells will be an essential reference for graduate students and researchers working on small-scale robotic systems for cell manipulation and characterization, healthcare professionals interested in nanoscale, microscale, milli-scale robotic techniques for clinical cell surgeries and assisted reproduction, and engineers developing small-scale robotic systems for biomedical engineering, biology, and medicine.

Autonomous Robot-Aided Optical Manipulation for Biological Cells

Author: Mingyang Xie

Publisher: Academic Press

Published: 2021-05-12

Total Pages: 190

ISBN-13: 0128235926

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Autonomous Robot-Aided Optical Manipulation for Biological Cells gives a systematically and almost self-contained description of the many facets of modeling, sensing, and control techniques or experimentally exploring emerging trends in optical manipulation of biological cell in micro/nanorobotics systems. To achieve biomedical applications, reliability design, modeling, and precision control are vitally important for the development of engineering systems. With the advances in modeling, sensing, and control techniques, it is opportunistic to exploit them for the benefit of reliability design, actuation, and precision control of micro/nanomanipulation systems to expanding the applications of robot at the micro and nano scales, especially in biomedical engineering. This book presents new techniques in reliability modeling and advanced control of robot-aided optical manipulation of biological cells systems. The book will be beneficial to the researchers within robotics, mechatronics, biomedical engineering, and automatic control society, including both academic and industrial parts. Provides a series of latest results in, including but not limited to, design, sensing, actuation, modeling, and control of micro/nano manipulation system using optical tweezers Gives recent advances of theory, technological aspects, and applications of advanced sensing, actuation, modeling and control methodologies in biomedical engineering applications Offers simulation and experimental results in each chapter in order to reflect the biomedical engineering practice, yet demonstrate the main focus of the developed design, analysis and synthesis approaches

Book Synopsis Autonomous Robot-Aided Optical Manipulation for Biological Cells by : Mingyang Xie

Download or read book Autonomous Robot-Aided Optical Manipulation for Biological Cells written by Mingyang Xie and published by Academic Press. This book was released on 2021-05-12 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autonomous Robot-Aided Optical Manipulation for Biological Cells gives a systematically and almost self-contained description of the many facets of modeling, sensing, and control techniques or experimentally exploring emerging trends in optical manipulation of biological cell in micro/nanorobotics systems. To achieve biomedical applications, reliability design, modeling, and precision control are vitally important for the development of engineering systems. With the advances in modeling, sensing, and control techniques, it is opportunistic to exploit them for the benefit of reliability design, actuation, and precision control of micro/nanomanipulation systems to expanding the applications of robot at the micro and nano scales, especially in biomedical engineering. This book presents new techniques in reliability modeling and advanced control of robot-aided optical manipulation of biological cells systems. The book will be beneficial to the researchers within robotics, mechatronics, biomedical engineering, and automatic control society, including both academic and industrial parts. Provides a series of latest results in, including but not limited to, design, sensing, actuation, modeling, and control of micro/nano manipulation system using optical tweezers Gives recent advances of theory, technological aspects, and applications of advanced sensing, actuation, modeling and control methodologies in biomedical engineering applications Offers simulation and experimental results in each chapter in order to reflect the biomedical engineering practice, yet demonstrate the main focus of the developed design, analysis and synthesis approaches

Robotic Single Cell Manipulation for Biological and Clinical Applications

Author: Clement Leung

Publisher:

Published: 2011

Total Pages: 198

ISBN-13: 9780494768341

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Single cell manipulation techniques have important applications in laboratory and clinical procedures such as intracytoplasmic sperm injection (ICSI) and polar body biopsy for preimplantation genetic diagnosis (PGD). Conventionally, manipulation of cells conducted in these procedures have been performed manually, which entails long training hours and stringent skills. Conventional single cell manipulation also has the limitation of low success rates and poor reproducibility due to human fatigue and skill variations across operators. This research focuses on the integration of computer vision microscopy and control algorithms into a system for the automation of the following single cell manipulation techniques: (1) sperm immobilization, (2) cell aspiration into a micropipette, and cell positioning inside a micropipette, and (3) rotational control of cells in three-dimensions. These automated techniques eliminate the need for significant human involvement and long training. Through experimental trials on live cells, the automated techniques demonstrated high success rates.

Book Synopsis Robotic Single Cell Manipulation for Biological and Clinical Applications by : Clement Leung

Download or read book Robotic Single Cell Manipulation for Biological and Clinical Applications written by Clement Leung and published by . This book was released on 2011 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Single cell manipulation techniques have important applications in laboratory and clinical procedures such as intracytoplasmic sperm injection (ICSI) and polar body biopsy for preimplantation genetic diagnosis (PGD). Conventionally, manipulation of cells conducted in these procedures have been performed manually, which entails long training hours and stringent skills. Conventional single cell manipulation also has the limitation of low success rates and poor reproducibility due to human fatigue and skill variations across operators. This research focuses on the integration of computer vision microscopy and control algorithms into a system for the automation of the following single cell manipulation techniques: (1) sperm immobilization, (2) cell aspiration into a micropipette, and cell positioning inside a micropipette, and (3) rotational control of cells in three-dimensions. These automated techniques eliminate the need for significant human involvement and long training. Through experimental trials on live cells, the automated techniques demonstrated high success rates.

Millimeter-Scale Magnetically Actuated Robotic Tools for Surgery and Cell Manipulation

Author: Onaizah Onaizah

Publisher:

Published: 2020

Total Pages: 0

ISBN-13:

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Small scale robots are precise end-effectors that can manipulate objects with a high degree of accuracy. Many surgical and on-chip tasks can be performed by manipulating these robots in their dedicated environments. Mobile untethered surgical robots are an attractive research area because of their ability to maneuver inside small and constrained environments and perform tasks that were previously considered infeasible. These robots enable us to make surgery minimally invasive. Surgeons can drill a hole in your skull and insert the tools inside the ventricles from where they can navigate their way to either cut or grasp tissue. Because these robots are too small for electronics and on-board power, they are often actuated remotely using magnetic fields as these field can penetrate most environments and are relatively safe for biological organisms. This makes them an ideal tool to use inside the human body and for on-chip applications. Magnetic tools can be developed and placed inside microfluidic platforms for cell manipulation such as sorting and stimulation. Both on-chip and mobile devices are explored in this thesis focusing on applications related to cell manipulation as well as surgical tools. Specifically, this thesis involves a discussion on the development of a pair of micro-surgical scissors for cutting of soft tissues as well as a magnetically oscillating beam that can be used to apply shear stress to cells and used for cell sorting purposes.

Book Synopsis Millimeter-Scale Magnetically Actuated Robotic Tools for Surgery and Cell Manipulation by : Onaizah Onaizah

Download or read book Millimeter-Scale Magnetically Actuated Robotic Tools for Surgery and Cell Manipulation written by Onaizah Onaizah and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Small scale robots are precise end-effectors that can manipulate objects with a high degree of accuracy. Many surgical and on-chip tasks can be performed by manipulating these robots in their dedicated environments. Mobile untethered surgical robots are an attractive research area because of their ability to maneuver inside small and constrained environments and perform tasks that were previously considered infeasible. These robots enable us to make surgery minimally invasive. Surgeons can drill a hole in your skull and insert the tools inside the ventricles from where they can navigate their way to either cut or grasp tissue. Because these robots are too small for electronics and on-board power, they are often actuated remotely using magnetic fields as these field can penetrate most environments and are relatively safe for biological organisms. This makes them an ideal tool to use inside the human body and for on-chip applications. Magnetic tools can be developed and placed inside microfluidic platforms for cell manipulation such as sorting and stimulation. Both on-chip and mobile devices are explored in this thesis focusing on applications related to cell manipulation as well as surgical tools. Specifically, this thesis involves a discussion on the development of a pair of micro-surgical scissors for cutting of soft tissues as well as a magnetically oscillating beam that can be used to apply shear stress to cells and used for cell sorting purposes.

Microdevices and Microsystems for Cell Manipulation

Author: Aaron T. Ohta

Publisher: MDPI

Published: 2018-07-03

Total Pages: 179

ISBN-13: 3038426180

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This book is a printed edition of the Special Issue "Microdevices and Microsystems for Cell Manipulation" that was published in Micromachines

Book Synopsis Microdevices and Microsystems for Cell Manipulation by : Aaron T. Ohta

Download or read book Microdevices and Microsystems for Cell Manipulation written by Aaron T. Ohta and published by MDPI. This book was released on 2018-07-03 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Microdevices and Microsystems for Cell Manipulation" that was published in Micromachines

Fundamentals of Mechanics of Robotic Manipulation

Author: Marco Ceccarelli

Publisher: Springer Nature

Published: 2022-03-30

Total Pages: 398

ISBN-13: 3030908488

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The book explores the fundamental issues of robot mechanics for both the analysis and design of manipulations, manipulators and grippers, taking into account a central role of mechanics and mechanical structures in the development and use of robotic systems with mechatronic design. It examines manipulations that can be performed by robotic manipulators. The contents of the book are kept at a fairly practical level with the aim to teach how to model, simulate, and operate robotic mechanical systems. The chapters have been written and organized in a way that they can be red even separately, so that they can be used separately for different courses and purposes. The introduction illustrates motivations and historical developments of robotic mechanical systems. Chapter 2 describes the analysis and design of manipulations by automatic machinery and robots; chapter 3 deals with the mechanics of serial-chain manipulators with the aim to propose algorithms for analysis, simulation, and design purposes; chapter 4 introduces the mechanics of parallel manipulators; chapter 5 addresses the attention to mechanical grippers and related mechanics of grasping.

Book Synopsis Fundamentals of Mechanics of Robotic Manipulation by : Marco Ceccarelli

Download or read book Fundamentals of Mechanics of Robotic Manipulation written by Marco Ceccarelli and published by Springer Nature. This book was released on 2022-03-30 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book explores the fundamental issues of robot mechanics for both the analysis and design of manipulations, manipulators and grippers, taking into account a central role of mechanics and mechanical structures in the development and use of robotic systems with mechatronic design. It examines manipulations that can be performed by robotic manipulators. The contents of the book are kept at a fairly practical level with the aim to teach how to model, simulate, and operate robotic mechanical systems. The chapters have been written and organized in a way that they can be red even separately, so that they can be used separately for different courses and purposes. The introduction illustrates motivations and historical developments of robotic mechanical systems. Chapter 2 describes the analysis and design of manipulations by automatic machinery and robots; chapter 3 deals with the mechanics of serial-chain manipulators with the aim to propose algorithms for analysis, simulation, and design purposes; chapter 4 introduces the mechanics of parallel manipulators; chapter 5 addresses the attention to mechanical grippers and related mechanics of grasping.

Development of a Five Degree-of-freedom Robot for the Manipulation of Biological Cells

Author:

Publisher:

Published: 2007

Total Pages:

ISBN-13:

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Studies of individual cells via microscopy and microinjection are a key component in research on gene functions, cancer, stem cells, and reproductive technology. As biomedical experiments become more complex, there is an urgent need for robotic systems to: improve cell manipulation, increase throughput, reduce lost cells, and improve reaction detection. Automation of these tasks using visual servoing creates significant benefits for biomedical laboratories including repeatability of experiments, higher throughput, and a controlled environment capable of operating 24 hours a day. In this work the design and development of a new five degree-of-freedom biomanipulator designed for single-cell microinjection, is described. The biomanipulator employs three degrees of linear motion and two degrees of rotation. This provides the ability to manipulate/micro-inject cells at varying orientations, thereby increasing flexibility in dealing with complex operations such as injecting clustered cells. The capability of the biomanipulator is shown with preliminary experimental results using mouse myeloma cells.

Book Synopsis Development of a Five Degree-of-freedom Robot for the Manipulation of Biological Cells by :

Download or read book Development of a Five Degree-of-freedom Robot for the Manipulation of Biological Cells written by and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies of individual cells via microscopy and microinjection are a key component in research on gene functions, cancer, stem cells, and reproductive technology. As biomedical experiments become more complex, there is an urgent need for robotic systems to: improve cell manipulation, increase throughput, reduce lost cells, and improve reaction detection. Automation of these tasks using visual servoing creates significant benefits for biomedical laboratories including repeatability of experiments, higher throughput, and a controlled environment capable of operating 24 hours a day. In this work the design and development of a new five degree-of-freedom biomanipulator designed for single-cell microinjection, is described. The biomanipulator employs three degrees of linear motion and two degrees of rotation. This provides the ability to manipulate/micro-inject cells at varying orientations, thereby increasing flexibility in dealing with complex operations such as injecting clustered cells. The capability of the biomanipulator is shown with preliminary experimental results using mouse myeloma cells.

Robotics

Author: Oliver Brock

Publisher: MIT Press

Published: 2009

Total Pages: 334

ISBN-13: 0262513099

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State-of-the-art robotics research on such topics as manipulation, motion planning, micro-robotics, distributed systems, autonomous navigation, and mapping. Robotics: Science and Systems IV spans a wide spectrum of robotics, bringing together researchers working on the foundations of robotics, robotics applications, and analysis of robotics systems. This volume presents the proceedings of the fourth annual Robotics: Science and Systems conference, held in 2008 at the Swiss Federal Institute of Technology in Zurich. The papers presented cover a range of topics, including computer vision, mapping, terrain identification, distributed systems, localization, manipulation, collision avoidance, multibody dynamics, obstacle detection, microrobotic systems, pursuit-evasion, grasping and manipulation, tracking, spatial kinematics, machine learning, and sensor networks as well as such applications as autonomous driving and design of manipulators for use in functional-MRI. The conference and its proceedings reflect not only the tremendous growth of robotics as a discipline but also the desire in the robotics community for a flagship event at which the best of the research in the field can be presented.

Book Synopsis Robotics by : Oliver Brock

Download or read book Robotics written by Oliver Brock and published by MIT Press. This book was released on 2009 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: State-of-the-art robotics research on such topics as manipulation, motion planning, micro-robotics, distributed systems, autonomous navigation, and mapping. Robotics: Science and Systems IV spans a wide spectrum of robotics, bringing together researchers working on the foundations of robotics, robotics applications, and analysis of robotics systems. This volume presents the proceedings of the fourth annual Robotics: Science and Systems conference, held in 2008 at the Swiss Federal Institute of Technology in Zurich. The papers presented cover a range of topics, including computer vision, mapping, terrain identification, distributed systems, localization, manipulation, collision avoidance, multibody dynamics, obstacle detection, microrobotic systems, pursuit-evasion, grasping and manipulation, tracking, spatial kinematics, machine learning, and sensor networks as well as such applications as autonomous driving and design of manipulators for use in functional-MRI. The conference and its proceedings reflect not only the tremendous growth of robotics as a discipline but also the desire in the robotics community for a flagship event at which the best of the research in the field can be presented.