Scientific Methods to Evaluate Potential Reduced-risk Tobacco Products

Scientific Methods to Evaluate Potential Reduced-risk Tobacco Products

Author: Catherine St. Hilaire

Publisher:

Published: 2007

Total Pages: 190

ISBN-13:

DOWNLOAD EBOOK

A new study from the Life Sciences Research Office, Inc. (LSRO), Scientific Methods to Evaluate Potential Reduced-Risk Tobacco Products, outlines laboratory and clinical testing approaches for the assessment of tobacco products with the potential to reduce the risks of cigarette smoking for individuals who switch from cigarettes to these products. This report and the scientific evaluation approach outlined by LSRO will be of interest to a number of audiences including academic, government and industry researchers; tobacco control and public health organizations; agencies with regulatory oversight of tobacco products, such as the Federal Trade Commission; as well as individuals involved in the development of legislation providing regulatory authority over tobacco products to public health organizations, such as the Food and Drug Administration, and agency staff. The report will also be of interest to current smokers (and their friends and family) who are unable or unwilling to quit smoking but are interested in reducing their risks due to smoking. This report was produced under a contract between Philip Morris USA, Inc. (Philip Morris) and LSRO. Findings, conclusions, and recommendations were developed independently of Philip Morris and represent the views of LSRO. - Publishers website.


Book Synopsis Scientific Methods to Evaluate Potential Reduced-risk Tobacco Products by : Catherine St. Hilaire

Download or read book Scientific Methods to Evaluate Potential Reduced-risk Tobacco Products written by Catherine St. Hilaire and published by . This book was released on 2007 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new study from the Life Sciences Research Office, Inc. (LSRO), Scientific Methods to Evaluate Potential Reduced-Risk Tobacco Products, outlines laboratory and clinical testing approaches for the assessment of tobacco products with the potential to reduce the risks of cigarette smoking for individuals who switch from cigarettes to these products. This report and the scientific evaluation approach outlined by LSRO will be of interest to a number of audiences including academic, government and industry researchers; tobacco control and public health organizations; agencies with regulatory oversight of tobacco products, such as the Federal Trade Commission; as well as individuals involved in the development of legislation providing regulatory authority over tobacco products to public health organizations, such as the Food and Drug Administration, and agency staff. The report will also be of interest to current smokers (and their friends and family) who are unable or unwilling to quit smoking but are interested in reducing their risks due to smoking. This report was produced under a contract between Philip Morris USA, Inc. (Philip Morris) and LSRO. Findings, conclusions, and recommendations were developed independently of Philip Morris and represent the views of LSRO. - Publishers website.

Public Health Consequences of E-Cigarettes

Public Health Consequences of E-Cigarettes

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2018-05-18

Total Pages: 775

ISBN-13: 030946837X

DOWNLOAD EBOOK

Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes. Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.


Book Synopsis Public Health Consequences of E-Cigarettes by : National Academies of Sciences, Engineering, and Medicine

Download or read book Public Health Consequences of E-Cigarettes written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-05-18 with total page 775 pages. Available in PDF, EPUB and Kindle. Book excerpt: Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes. Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.

Scientific Standards for Studies on Modified Risk Tobacco Products

Scientific Standards for Studies on Modified Risk Tobacco Products

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2012-04-19

Total Pages: 370

ISBN-13: 0309223989

DOWNLOAD EBOOK

Smoking-related diseases kill more Americans than alcohol, illegal drugs, murder and suicide combined. The passage of the Family Smoking Prevention and Tobacco Control Act of 2009 gave the FDA authority to regulate "modified risk tobacco products" (MRTPs), tobacco products that are either designed or advertised to reduce harm or the risk of tobacco-related disease. MRTPs must submit to the FDA scientific evidence to demonstrate the product has the potential to reduce tobacco related harms as compared to conventional tobacco products. The IOM identifies minimum standards for scientific studies that an applicant would need to complete to obtain an order to market the product from the FDA.


Book Synopsis Scientific Standards for Studies on Modified Risk Tobacco Products by : Institute of Medicine

Download or read book Scientific Standards for Studies on Modified Risk Tobacco Products written by Institute of Medicine and published by National Academies Press. This book was released on 2012-04-19 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smoking-related diseases kill more Americans than alcohol, illegal drugs, murder and suicide combined. The passage of the Family Smoking Prevention and Tobacco Control Act of 2009 gave the FDA authority to regulate "modified risk tobacco products" (MRTPs), tobacco products that are either designed or advertised to reduce harm or the risk of tobacco-related disease. MRTPs must submit to the FDA scientific evidence to demonstrate the product has the potential to reduce tobacco related harms as compared to conventional tobacco products. The IOM identifies minimum standards for scientific studies that an applicant would need to complete to obtain an order to market the product from the FDA.

How Tobacco Smoke Causes Disease

How Tobacco Smoke Causes Disease

Author:

Publisher:

Published: 2010

Total Pages: 728

ISBN-13:

DOWNLOAD EBOOK

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.


Book Synopsis How Tobacco Smoke Causes Disease by :

Download or read book How Tobacco Smoke Causes Disease written by and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Biological Effects Assessment in the Evaluation of Potential Reduced-Risk Tobacco Products

Biological Effects Assessment in the Evaluation of Potential Reduced-Risk Tobacco Products

Author: Amy M. Brownawell

Publisher: Life Sciences Research Office

Published: 2007-01-01

Total Pages: 242

ISBN-13: 9780975316788

DOWNLOAD EBOOK


Book Synopsis Biological Effects Assessment in the Evaluation of Potential Reduced-Risk Tobacco Products by : Amy M. Brownawell

Download or read book Biological Effects Assessment in the Evaluation of Potential Reduced-Risk Tobacco Products written by Amy M. Brownawell and published by Life Sciences Research Office. This book was released on 2007-01-01 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Potential Reduced Exposure, Reduced Risk Tobacco Products

Potential Reduced Exposure, Reduced Risk Tobacco Products

Author: United States. Congress. House. Committee on Government Reform

Publisher:

Published: 2003

Total Pages: 364

ISBN-13:

DOWNLOAD EBOOK


Book Synopsis Potential Reduced Exposure, Reduced Risk Tobacco Products by : United States. Congress. House. Committee on Government Reform

Download or read book Potential Reduced Exposure, Reduced Risk Tobacco Products written by United States. Congress. House. Committee on Government Reform and published by . This book was released on 2003 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Understanding the U.S. Illicit Tobacco Market

Understanding the U.S. Illicit Tobacco Market

Author: National Research Council

Publisher: National Academies Press

Published: 2015-04-30

Total Pages: 316

ISBN-13: 0309317150

DOWNLOAD EBOOK

Tobacco use has declined because of measures such as high taxes on tobacco products and bans on advertising, but worldwide there are still more than one billion people who regularly use tobacco, including many who purchase products illicitly. By contrast to many other commodities, taxes comprise a substantial portion of the retail price of cigarettes in the United States and most other nations. Large tax differentials between jurisdictions increase incentives for participation in existing illicit tobacco markets. In the United States, the illicit tobacco market consists mostly of bootlegging from low-tax states to high-tax states and is less affected by large-scale smuggling or illegal production as in other countries. In the future, nonprice regulation of cigarettes - such as product design, formulation, and packaging - could in principle, contribute to the development of new types of illicit tobacco markets. Understanding the U.S. Illicit Tobacco Market reviews the nature of illicit tobacco markets, evidence for policy effects, and variations among different countries with a focus on implications for the United States. This report estimates the portion of the total U.S. tobacco market represented by illicit sales has grown in recent years and is now between 8.5 percent and 21 percent. This represents between 1.24 to 2.91 billion packs of cigarettes annually and between $2.95 billion and $6.92 billion in lost gross state and local tax revenues. Understanding the U.S. Illicit Tobacco Market describes the complex system associated with illicit tobacco use by exploring some of the key features of that market - the cigarette supply chain, illicit procurement schemes, the major actors in the illicit trade, and the characteristics of users of illicit tobacco. This report draws on domestic and international experiences with the illicit tobacco trade to identify a range of possible policy and enforcement interventions by the U.S. federal government and/or states and localities.


Book Synopsis Understanding the U.S. Illicit Tobacco Market by : National Research Council

Download or read book Understanding the U.S. Illicit Tobacco Market written by National Research Council and published by National Academies Press. This book was released on 2015-04-30 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tobacco use has declined because of measures such as high taxes on tobacco products and bans on advertising, but worldwide there are still more than one billion people who regularly use tobacco, including many who purchase products illicitly. By contrast to many other commodities, taxes comprise a substantial portion of the retail price of cigarettes in the United States and most other nations. Large tax differentials between jurisdictions increase incentives for participation in existing illicit tobacco markets. In the United States, the illicit tobacco market consists mostly of bootlegging from low-tax states to high-tax states and is less affected by large-scale smuggling or illegal production as in other countries. In the future, nonprice regulation of cigarettes - such as product design, formulation, and packaging - could in principle, contribute to the development of new types of illicit tobacco markets. Understanding the U.S. Illicit Tobacco Market reviews the nature of illicit tobacco markets, evidence for policy effects, and variations among different countries with a focus on implications for the United States. This report estimates the portion of the total U.S. tobacco market represented by illicit sales has grown in recent years and is now between 8.5 percent and 21 percent. This represents between 1.24 to 2.91 billion packs of cigarettes annually and between $2.95 billion and $6.92 billion in lost gross state and local tax revenues. Understanding the U.S. Illicit Tobacco Market describes the complex system associated with illicit tobacco use by exploring some of the key features of that market - the cigarette supply chain, illicit procurement schemes, the major actors in the illicit trade, and the characteristics of users of illicit tobacco. This report draws on domestic and international experiences with the illicit tobacco trade to identify a range of possible policy and enforcement interventions by the U.S. federal government and/or states and localities.

E-Cigarette Use Among Youth and Young Adults: a Report of the Surgeon General

E-Cigarette Use Among Youth and Young Adults: a Report of the Surgeon General

Author: Centers for Disease Control and Prevention

Publisher:

Published: 2019-07-26

Total Pages: 293

ISBN-13: 9781082814914

DOWNLOAD EBOOK

Tobacco use among youth and young adults in any form, including e-cigarettes, is not safe. In recent years, e-cigarette use by youth and young adults has increased at an alarming rate. E-cigarettes are now the most commonly used tobacco product among youth in the United States. This timely report highlights the rapidly changing patterns of e-cigarette use among youth and young adults, assesses what we know about the health effects of using these products, and describes strategies that tobacco companies use to recruit our nation's youth and young adults to try and continue using e-cigarettes. The report also outlines interventions that can be adopted to minimize the harm these products cause to our nation's youth.E-cigarettes are tobacco products that deliver nicotine. Nicotine is a highly addictive substance, and many of today's youth who are using e-cigarettes could become tomorrow's cigarette smokers. Nicotine exposure can also harm brain development in ways that may affect the health and mental health of our kids.E-cigarette use among youth and young adults is associated with the use of other tobacco products, including conventional cigarettes. Because most tobacco use is established during adolescence, actions to prevent our nation's young people from the potential of a lifetime of nicotine addiction are critical.E-cigarette companies appear to be using many of the advertising tactics the tobacco industry used to persuade a new generation of young people to use their products. Companies are promoting their products through television and radio advertisements that use celebrities, sexual content, and claims of independence to glamorize these addictive products and make them appealing to young people.


Book Synopsis E-Cigarette Use Among Youth and Young Adults: a Report of the Surgeon General by : Centers for Disease Control and Prevention

Download or read book E-Cigarette Use Among Youth and Young Adults: a Report of the Surgeon General written by Centers for Disease Control and Prevention and published by . This book was released on 2019-07-26 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tobacco use among youth and young adults in any form, including e-cigarettes, is not safe. In recent years, e-cigarette use by youth and young adults has increased at an alarming rate. E-cigarettes are now the most commonly used tobacco product among youth in the United States. This timely report highlights the rapidly changing patterns of e-cigarette use among youth and young adults, assesses what we know about the health effects of using these products, and describes strategies that tobacco companies use to recruit our nation's youth and young adults to try and continue using e-cigarettes. The report also outlines interventions that can be adopted to minimize the harm these products cause to our nation's youth.E-cigarettes are tobacco products that deliver nicotine. Nicotine is a highly addictive substance, and many of today's youth who are using e-cigarettes could become tomorrow's cigarette smokers. Nicotine exposure can also harm brain development in ways that may affect the health and mental health of our kids.E-cigarette use among youth and young adults is associated with the use of other tobacco products, including conventional cigarettes. Because most tobacco use is established during adolescence, actions to prevent our nation's young people from the potential of a lifetime of nicotine addiction are critical.E-cigarette companies appear to be using many of the advertising tactics the tobacco industry used to persuade a new generation of young people to use their products. Companies are promoting their products through television and radio advertisements that use celebrities, sexual content, and claims of independence to glamorize these addictive products and make them appealing to young people.

Changes in Cigarette-related Disease Risks and Their Implication for Prevention and Control

Changes in Cigarette-related Disease Risks and Their Implication for Prevention and Control

Author:

Publisher:

Published: 1997

Total Pages: 608

ISBN-13:

DOWNLOAD EBOOK

This volume presents results from three large, more contemporary prospective mortality studies and provides longer followup for two of the older studies dating from the 1950's. When observations from the more contemporary studies are compared with those from the 1950's, one important but disturbing conclusion is apparent - mortality risks among continuing smokers, both males and females, have increased. In fact, relative risks for smokers compared to never-smokers have increased for all major smoking-related diseases - coronary heart disease (CHD), lung cancer, other smoking-related cancers, stroke, and chronic obstructive pulmonary disease (COPD). This increase over time in the relative risks for smokers compared to never-smokers has occured despite a dramatic decline in cardiovascular disease (CVD) death rates in the U.S. population, suggesting that the decline in CVD death rates has been proportionately greater among never-smokers than among continuing smokers. The clearest message that is drawn from the enormous quantity of data presented in this monograph is that smoking prevention and cessation efforts are complementary, not alternative, solutions to the current epidemic of diseases caused by smoking.


Book Synopsis Changes in Cigarette-related Disease Risks and Their Implication for Prevention and Control by :

Download or read book Changes in Cigarette-related Disease Risks and Their Implication for Prevention and Control written by and published by . This book was released on 1997 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents results from three large, more contemporary prospective mortality studies and provides longer followup for two of the older studies dating from the 1950's. When observations from the more contemporary studies are compared with those from the 1950's, one important but disturbing conclusion is apparent - mortality risks among continuing smokers, both males and females, have increased. In fact, relative risks for smokers compared to never-smokers have increased for all major smoking-related diseases - coronary heart disease (CHD), lung cancer, other smoking-related cancers, stroke, and chronic obstructive pulmonary disease (COPD). This increase over time in the relative risks for smokers compared to never-smokers has occured despite a dramatic decline in cardiovascular disease (CVD) death rates in the U.S. population, suggesting that the decline in CVD death rates has been proportionately greater among never-smokers than among continuing smokers. The clearest message that is drawn from the enormous quantity of data presented in this monograph is that smoking prevention and cessation efforts are complementary, not alternative, solutions to the current epidemic of diseases caused by smoking.

Growing Up Tobacco Free

Growing Up Tobacco Free

Author: Institute of Medicine

Publisher: National Academies Press

Published: 1994-02-01

Total Pages: 321

ISBN-13: 0309051290

DOWNLOAD EBOOK

Tobacco use kills more people than any other addiction and we know that addiction starts in childhood and youth. We all agree that youths should not smoke, but how can this be accomplished? What prevention messages will they find compelling? What effect does tobacco advertisingâ€"more than $10 million worth every dayâ€"have on youths? Can we responsibly and effectively restrict their access to tobacco products? These questions and more are addressed in Growing Up Tobacco Free, prepared by the Institute of Medicine to help everyone understand the troubling issues surrounding youths and tobacco use. Growing Up Tobacco Free provides a readable explanation of nicotine's effects and the process of addiction, and documents the search for an effective approach to preventing the use of cigarettes, chewing and spitting tobacco, and snuff by children and youths. It covers the results of recent initiatives to limit young people's access to tobacco and discusses approaches to controls or bans on tobacco sales, price sensitivity among adolescents, and arguments for and against taxation as a prevention strategy for tobacco use. The controversial area of tobacco advertising is thoroughly examined. With clear guidelines for public action, everyone can benefit by reading and acting on the messages in this comprehensive and compelling book.


Book Synopsis Growing Up Tobacco Free by : Institute of Medicine

Download or read book Growing Up Tobacco Free written by Institute of Medicine and published by National Academies Press. This book was released on 1994-02-01 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tobacco use kills more people than any other addiction and we know that addiction starts in childhood and youth. We all agree that youths should not smoke, but how can this be accomplished? What prevention messages will they find compelling? What effect does tobacco advertisingâ€"more than $10 million worth every dayâ€"have on youths? Can we responsibly and effectively restrict their access to tobacco products? These questions and more are addressed in Growing Up Tobacco Free, prepared by the Institute of Medicine to help everyone understand the troubling issues surrounding youths and tobacco use. Growing Up Tobacco Free provides a readable explanation of nicotine's effects and the process of addiction, and documents the search for an effective approach to preventing the use of cigarettes, chewing and spitting tobacco, and snuff by children and youths. It covers the results of recent initiatives to limit young people's access to tobacco and discusses approaches to controls or bans on tobacco sales, price sensitivity among adolescents, and arguments for and against taxation as a prevention strategy for tobacco use. The controversial area of tobacco advertising is thoroughly examined. With clear guidelines for public action, everyone can benefit by reading and acting on the messages in this comprehensive and compelling book.