Selective Glycosylations

Selective Glycosylations

Author: Clay S. Bennett

Publisher: John Wiley & Sons

Published: 2017-01-19

Total Pages: 500

ISBN-13: 3527696245

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A comprehensive summary of novel approaches to the stereoselective construction of glycosidic linkages, covering modern glycosylation methods and their use and application in natural product synthesis and drug discovery. Clearly divided into five sections, the first describes recent advances in classical methodologies in carbohydrate chemistry, while the second goes on to deal with newer chemistries developed to control selectivity in glycosylation reactions. Section three is devoted to selective glycosylation reactions that rely on the use of catalytic promoters. Section four describes modern approaches for controlling regioselectivity in carbohydrate synthesis. The final section focuses on new developments in the construction of "unusual" sugars and is rounded off by a presentation of modern procedures for the construction of glycosylated natural products. By providing the latest advances in glycosylation as well as information on mechanistic aspects of the reaction, this is an invaluable reference for both specialists and beginners in this booming interdisciplinary field that includes carbohydrate chemistry, organic synthesis, catalysis, and biochemistry.


Book Synopsis Selective Glycosylations by : Clay S. Bennett

Download or read book Selective Glycosylations written by Clay S. Bennett and published by John Wiley & Sons. This book was released on 2017-01-19 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive summary of novel approaches to the stereoselective construction of glycosidic linkages, covering modern glycosylation methods and their use and application in natural product synthesis and drug discovery. Clearly divided into five sections, the first describes recent advances in classical methodologies in carbohydrate chemistry, while the second goes on to deal with newer chemistries developed to control selectivity in glycosylation reactions. Section three is devoted to selective glycosylation reactions that rely on the use of catalytic promoters. Section four describes modern approaches for controlling regioselectivity in carbohydrate synthesis. The final section focuses on new developments in the construction of "unusual" sugars and is rounded off by a presentation of modern procedures for the construction of glycosylated natural products. By providing the latest advances in glycosylation as well as information on mechanistic aspects of the reaction, this is an invaluable reference for both specialists and beginners in this booming interdisciplinary field that includes carbohydrate chemistry, organic synthesis, catalysis, and biochemistry.

Selective Glycosylations

Selective Glycosylations

Author: Clay S. Bennett

Publisher: John Wiley & Sons

Published: 2017-01-25

Total Pages: 398

ISBN-13: 3527696229

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A comprehensive summary of novel approaches to the stereoselective construction of glycosidic linkages, covering modern glycosylation methods and their use and application in natural product synthesis and drug discovery. Clearly divided into five sections, the first describes recent advances in classical methodologies in carbohydrate chemistry, while the second goes on to deal with newer chemistries developed to control selectivity in glycosylation reactions. Section three is devoted to selective glycosylation reactions that rely on the use of catalytic promoters. Section four describes modern approaches for controlling regioselectivity in carbohydrate synthesis. The final section focuses on new developments in the construction of "unusual" sugars and is rounded off by a presentation of modern procedures for the construction of glycosylated natural products. By providing the latest advances in glycosylation as well as information on mechanistic aspects of the reaction, this is an invaluable reference for both specialists and beginners in this booming interdisciplinary field that includes carbohydrate chemistry, organic synthesis, catalysis, and biochemistry.


Book Synopsis Selective Glycosylations by : Clay S. Bennett

Download or read book Selective Glycosylations written by Clay S. Bennett and published by John Wiley & Sons. This book was released on 2017-01-25 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive summary of novel approaches to the stereoselective construction of glycosidic linkages, covering modern glycosylation methods and their use and application in natural product synthesis and drug discovery. Clearly divided into five sections, the first describes recent advances in classical methodologies in carbohydrate chemistry, while the second goes on to deal with newer chemistries developed to control selectivity in glycosylation reactions. Section three is devoted to selective glycosylation reactions that rely on the use of catalytic promoters. Section four describes modern approaches for controlling regioselectivity in carbohydrate synthesis. The final section focuses on new developments in the construction of "unusual" sugars and is rounded off by a presentation of modern procedures for the construction of glycosylated natural products. By providing the latest advances in glycosylation as well as information on mechanistic aspects of the reaction, this is an invaluable reference for both specialists and beginners in this booming interdisciplinary field that includes carbohydrate chemistry, organic synthesis, catalysis, and biochemistry.

Essentials of Glycobiology

Essentials of Glycobiology

Author: Ajit Varki

Publisher: CSHL Press

Published: 1999

Total Pages: 694

ISBN-13: 9780879696818

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Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.


Book Synopsis Essentials of Glycobiology by : Ajit Varki

Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Handbook of Chemical Glycosylation

Handbook of Chemical Glycosylation

Author: Alexei V. Demchenko

Publisher: John Wiley & Sons

Published: 2008-04-09

Total Pages: 524

ISBN-13: 3527621652

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Since carbohydrate oligomers are still a challenge in synthetic chemistry, this book on recent developments fulfils a great need. Covering the chemistry necessary to synthesize exact copies of these structures, top authors from all around the world comprehensively deal with synthesis from anomeric halides, from miscellaneous glycosyl donors, and by indirect and special methods, as well as 1-oxygen-and 1-sulfur-substituted derivatives. They demonstrate the best approach for the stereoselective formation of the intermonomeric bond, making this essential reading for every biochemist working in biosynthesis, the exploration of biopathways and vaccines.


Book Synopsis Handbook of Chemical Glycosylation by : Alexei V. Demchenko

Download or read book Handbook of Chemical Glycosylation written by Alexei V. Demchenko and published by John Wiley & Sons. This book was released on 2008-04-09 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since carbohydrate oligomers are still a challenge in synthetic chemistry, this book on recent developments fulfils a great need. Covering the chemistry necessary to synthesize exact copies of these structures, top authors from all around the world comprehensively deal with synthesis from anomeric halides, from miscellaneous glycosyl donors, and by indirect and special methods, as well as 1-oxygen-and 1-sulfur-substituted derivatives. They demonstrate the best approach for the stereoselective formation of the intermonomeric bond, making this essential reading for every biochemist working in biosynthesis, the exploration of biopathways and vaccines.

Fundamentals of Glycosylation

Fundamentals of Glycosylation

Author: Alok Raghav

Publisher: BoD – Books on Demand

Published: 2022-01-26

Total Pages: 102

ISBN-13: 1839691344

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The diverse phenomenon of post-translational modifications of biological macromolecules (proteins, lipids, and nucleic acids) includes phosphorylation, glycosylation, ubiquitination, nitrosylation, methylation, acetylation, lipidation, and proteolysis. The mechanism of protein glycosylation has an important role in the regulation of human health. This book identifies the fundamentals of glycosylation that help in understanding the concepts of protein glycosylation and its significance.


Book Synopsis Fundamentals of Glycosylation by : Alok Raghav

Download or read book Fundamentals of Glycosylation written by Alok Raghav and published by BoD – Books on Demand. This book was released on 2022-01-26 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: The diverse phenomenon of post-translational modifications of biological macromolecules (proteins, lipids, and nucleic acids) includes phosphorylation, glycosylation, ubiquitination, nitrosylation, methylation, acetylation, lipidation, and proteolysis. The mechanism of protein glycosylation has an important role in the regulation of human health. This book identifies the fundamentals of glycosylation that help in understanding the concepts of protein glycosylation and its significance.

Stereoselective Glycosylations

Stereoselective Glycosylations

Author: Dionysia Varvara Pepe

Publisher:

Published: 2021

Total Pages: 0

ISBN-13:

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Book Synopsis Stereoselective Glycosylations by : Dionysia Varvara Pepe

Download or read book Stereoselective Glycosylations written by Dionysia Varvara Pepe and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Glycochemical Synthesis

Glycochemical Synthesis

Author: Shang-Cheng Hung

Publisher: John Wiley & Sons

Published: 2016-09-12

Total Pages: 769

ISBN-13: 1119006473

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This book is a comprehensive and concise review on principles, strategies, and crucial advances in glycochemistry. It focuses on synthesis and practical applications and emphasizes state-of-the-art approaches to the assembly and design of sugars. • Provides detailed discussion on specific topics like oligosaccharide assembly and design of sugars, techniques in glycoconjugate preparation, multivalency, and carbohydrate-based drug design • Uses notable examples, like solution-based one-pot methods and automated methods for sugar assembly, to illustrate important concepts and advances in a rapidly emerging field • Discusses practical applications of carbohydrates, like medicine, therapeutics, drug and vaccine development


Book Synopsis Glycochemical Synthesis by : Shang-Cheng Hung

Download or read book Glycochemical Synthesis written by Shang-Cheng Hung and published by John Wiley & Sons. This book was released on 2016-09-12 with total page 769 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive and concise review on principles, strategies, and crucial advances in glycochemistry. It focuses on synthesis and practical applications and emphasizes state-of-the-art approaches to the assembly and design of sugars. • Provides detailed discussion on specific topics like oligosaccharide assembly and design of sugars, techniques in glycoconjugate preparation, multivalency, and carbohydrate-based drug design • Uses notable examples, like solution-based one-pot methods and automated methods for sugar assembly, to illustrate important concepts and advances in a rapidly emerging field • Discusses practical applications of carbohydrates, like medicine, therapeutics, drug and vaccine development

Glycosylation

Glycosylation

Author: Stefana Petrescu

Publisher: BoD – Books on Demand

Published: 2012-09-26

Total Pages: 452

ISBN-13: 9535107712

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This book, outlining the concepts of glycobiology, is a suite of reviews and articles written by a team of acknowledged researchers and covers some of the key topics in the field. Covering a wide range of theoretical and practical issues in the field of glycobiology, the Glycosylation book will be of an immediate value for students, academics and researchers involved in drug glycoengineering and biomedical research.


Book Synopsis Glycosylation by : Stefana Petrescu

Download or read book Glycosylation written by Stefana Petrescu and published by BoD – Books on Demand. This book was released on 2012-09-26 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, outlining the concepts of glycobiology, is a suite of reviews and articles written by a team of acknowledged researchers and covers some of the key topics in the field. Covering a wide range of theoretical and practical issues in the field of glycobiology, the Glycosylation book will be of an immediate value for students, academics and researchers involved in drug glycoengineering and biomedical research.

Protein Glycosylation

Protein Glycosylation

Author: Roslyn M. Bill

Publisher: Springer Science & Business Media

Published: 1998-11-30

Total Pages: 536

ISBN-13: 9780792383376

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Protein Glycosylation provides clear, up-to-date, and integrated coverage of key topics in this field. Particular emphasis is placed on the biosynthetic pathways that result in a wide variety of identified protein-bound oligosaccharides. Protein Glycosylation begins with an overview of the chemical structures of mono- and oligosaccharides, to provide a scientific basis for the later chapters. The book includes discussions on the purification, function, and enzyme kinetics of selected glycosidases and glycotransferases, as well as a review of the roles of oligosaccharides in glycoprotein function and the in vivo role of glycoproteins themselves. Finally, the in vitro synthesis of glycoproteins is presented, together with future directions in glycobiology. Protein Glycosylation serves as an excellent text for upper-level undergraduate and graduate students as well as a reference for those scientists whose training is not in glycobiology but who are moving into this field.


Book Synopsis Protein Glycosylation by : Roslyn M. Bill

Download or read book Protein Glycosylation written by Roslyn M. Bill and published by Springer Science & Business Media. This book was released on 1998-11-30 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein Glycosylation provides clear, up-to-date, and integrated coverage of key topics in this field. Particular emphasis is placed on the biosynthetic pathways that result in a wide variety of identified protein-bound oligosaccharides. Protein Glycosylation begins with an overview of the chemical structures of mono- and oligosaccharides, to provide a scientific basis for the later chapters. The book includes discussions on the purification, function, and enzyme kinetics of selected glycosidases and glycotransferases, as well as a review of the roles of oligosaccharides in glycoprotein function and the in vivo role of glycoproteins themselves. Finally, the in vitro synthesis of glycoproteins is presented, together with future directions in glycobiology. Protein Glycosylation serves as an excellent text for upper-level undergraduate and graduate students as well as a reference for those scientists whose training is not in glycobiology but who are moving into this field.

The S-benzoxazolyl Leaving Group in Selective Glycosylation Reactions

The S-benzoxazolyl Leaving Group in Selective Glycosylation Reactions

Author: Benjamin N. Harris

Publisher:

Published: 2010

Total Pages: 190

ISBN-13:

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Book Synopsis The S-benzoxazolyl Leaving Group in Selective Glycosylation Reactions by : Benjamin N. Harris

Download or read book The S-benzoxazolyl Leaving Group in Selective Glycosylation Reactions written by Benjamin N. Harris and published by . This book was released on 2010 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: