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Download or read book Space Radiation Cancer Risk Projections for Exploration Missions: Uncertainty Reduction and Mitigation written by and published by DIANE Publishing. This book was released on 2002 with total page 66 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author: National Aeronautics and Space Administration (NASA)
Publisher: Createspace Independent Publishing Platform
Published: 2018-06-11
Total Pages: 64
ISBN-13: 9781721000036
DOWNLOAD EBOOKIn this paper we discuss expected lifetime excess cancer risks for astronauts returning from exploration class missions. For the first time we make a quantitative assessment of uncertainties in cancer risk projections for space radiation exposures. Late effects from the high charge and energy (HZE) ions present in the galactic cosmic rays including cancer and the poorly understood risks to the central nervous system constitute the major risks. Methods used to project risk in low Earth orbit are seen as highly uncertain for projecting risks on exploration missions because of the limited radiobiology data available for estimating HZE ion risks. Cancer risk projections are described as a product of many biological and physical factors, each of which has a differential range of uncertainty due to lack of data and knowledge. Monte-Carlo sampling from subjective error distributions represents the lack of knowledge in each factor to quantify risk projection overall uncertainty. Cancer risk analysis is applied to several exploration mission scenarios. At solar minimum, the number of days in space where career risk of less than the limiting 3% excess cancer mortality can be assured at a 95% confidence level is found to be only of the order of 100 days.Cucinotta, Francis and Badhwar, Gautam and Saganti, Premkumar and Schimmerling, Walter and Wilson, John and Peterson, Leif and Dicello, JohnJohnson Space Center; Langley Research CenterASTRONAUTS; CANCER; GALACTIC COSMIC RAYS; RISK; SPACE EXPLORATION; PLANETARY ENVIRONMENTS; RADIATION HAZARDS; CONFIDENCE LIMITS; LOW EARTH ORBITS; MONTE CARLO METHOD; RADIOBIOLOGY; RADIATION DOSAGE; MORTALITY; IONS; SPACE MISSIONS; MANNED SPACE FLIGHT
Download or read book Space Radiation Cancer Risk Projections for Exploration Missions written by National Aeronautics and Space Administration (NASA) and published by Createspace Independent Publishing Platform. This book was released on 2018-06-11 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this paper we discuss expected lifetime excess cancer risks for astronauts returning from exploration class missions. For the first time we make a quantitative assessment of uncertainties in cancer risk projections for space radiation exposures. Late effects from the high charge and energy (HZE) ions present in the galactic cosmic rays including cancer and the poorly understood risks to the central nervous system constitute the major risks. Methods used to project risk in low Earth orbit are seen as highly uncertain for projecting risks on exploration missions because of the limited radiobiology data available for estimating HZE ion risks. Cancer risk projections are described as a product of many biological and physical factors, each of which has a differential range of uncertainty due to lack of data and knowledge. Monte-Carlo sampling from subjective error distributions represents the lack of knowledge in each factor to quantify risk projection overall uncertainty. Cancer risk analysis is applied to several exploration mission scenarios. At solar minimum, the number of days in space where career risk of less than the limiting 3% excess cancer mortality can be assured at a 95% confidence level is found to be only of the order of 100 days.Cucinotta, Francis and Badhwar, Gautam and Saganti, Premkumar and Schimmerling, Walter and Wilson, John and Peterson, Leif and Dicello, JohnJohnson Space Center; Langley Research CenterASTRONAUTS; CANCER; GALACTIC COSMIC RAYS; RISK; SPACE EXPLORATION; PLANETARY ENVIRONMENTS; RADIATION HAZARDS; CONFIDENCE LIMITS; LOW EARTH ORBITS; MONTE CARLO METHOD; RADIOBIOLOGY; RADIATION DOSAGE; MORTALITY; IONS; SPACE MISSIONS; MANNED SPACE FLIGHT
Author: National Research Council
Publisher: National Academies Press
Published: 2012-03-19
Total Pages: 86
ISBN-13: 030925308X
DOWNLOAD EBOOKNASA's current missions to the International Space Station (ISS) and potential future exploration missions involving extended stays by astronauts on the lunar surface, as well as the possibility of near- Earth object (NEO) or Mars missions, present challenges in protecting astronauts from radiation risks. These risks arise from a number of sources, including solar particle events (SPEs), galactic cosmic rays (GCRs), secondary radiation from surface impacts, and even the nuclear isotope power sources transported with the astronauts. The serious early and late radiation health effects potentially posed by these exposures are equally varied, ranging from early signs of radiation sickness to cancer induction. Other possible effects include central nervous system damage, cataracts, cardiovascular damage, heritable effects, impaired wound healing, and infertility. Recent research, much of which has been sponsored by NASA, has focused on understanding and quantifying the radiation health risks posed by space radiation environments. Although many aspects of the space radiation environments are now relatively well characterized, important uncertainties still exist regarding biological effects and thus regarding the level and types of risks faced by astronauts. This report presents an evaluation of NASA's proposed space radiation cancer risk assessment model, which is described in the 2011 NASA report, Space Radiation Cancer Risk Projections and Uncertainties-2010. The evaluation in Technical Evaluation of the NASA Model for Cancer Risk to Astronauts Due to Space Radiation considers the model components, input data (for the radiation types, estimated doses, and epidemiology), and the associated uncertainties. This report also identifies gaps in NASA's current research strategy for reducing the uncertainties in cancer induction risks.
Download or read book Technical Evaluation of the NASA Model for Cancer Risk to Astronauts Due to Space Radiation written by National Research Council and published by National Academies Press. This book was released on 2012-03-19 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: NASA's current missions to the International Space Station (ISS) and potential future exploration missions involving extended stays by astronauts on the lunar surface, as well as the possibility of near- Earth object (NEO) or Mars missions, present challenges in protecting astronauts from radiation risks. These risks arise from a number of sources, including solar particle events (SPEs), galactic cosmic rays (GCRs), secondary radiation from surface impacts, and even the nuclear isotope power sources transported with the astronauts. The serious early and late radiation health effects potentially posed by these exposures are equally varied, ranging from early signs of radiation sickness to cancer induction. Other possible effects include central nervous system damage, cataracts, cardiovascular damage, heritable effects, impaired wound healing, and infertility. Recent research, much of which has been sponsored by NASA, has focused on understanding and quantifying the radiation health risks posed by space radiation environments. Although many aspects of the space radiation environments are now relatively well characterized, important uncertainties still exist regarding biological effects and thus regarding the level and types of risks faced by astronauts. This report presents an evaluation of NASA's proposed space radiation cancer risk assessment model, which is described in the 2011 NASA report, Space Radiation Cancer Risk Projections and Uncertainties-2010. The evaluation in Technical Evaluation of the NASA Model for Cancer Risk to Astronauts Due to Space Radiation considers the model components, input data (for the radiation types, estimated doses, and epidemiology), and the associated uncertainties. This report also identifies gaps in NASA's current research strategy for reducing the uncertainties in cancer induction risks.
Author: National Research Council
Publisher: National Academies Press
Published: 2008-05-29
Total Pages: 132
ISBN-13: 0309185726
DOWNLOAD EBOOKAs part of the Vision for Space Exploration (VSE), NASA is planning for humans to revisit the Moon and someday go to Mars. An important consideration in this effort is protection against the exposure to space radiation. That radiation might result in severe long-term health consequences for astronauts on such missions if they are not adequately shielded. To help with these concerns, NASA asked the NRC to further the understanding of the risks of space radiation, to evaluate radiation shielding requirements, and recommend a strategic plan for developing appropriate mitigation capabilities. This book presents an assessment of current knowledge of the radiation environment; an examination of the effects of radiation on biological systems and mission equipment; an analysis of current plans for radiation protection; and a strategy for mitigating the risks to VSE astronauts.
Download or read book Managing Space Radiation Risk in the New Era of Space Exploration written by National Research Council and published by National Academies Press. This book was released on 2008-05-29 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: As part of the Vision for Space Exploration (VSE), NASA is planning for humans to revisit the Moon and someday go to Mars. An important consideration in this effort is protection against the exposure to space radiation. That radiation might result in severe long-term health consequences for astronauts on such missions if they are not adequately shielded. To help with these concerns, NASA asked the NRC to further the understanding of the risks of space radiation, to evaluate radiation shielding requirements, and recommend a strategic plan for developing appropriate mitigation capabilities. This book presents an assessment of current knowledge of the radiation environment; an examination of the effects of radiation on biological systems and mission equipment; an analysis of current plans for radiation protection; and a strategy for mitigating the risks to VSE astronauts.
Author: Jancy C. McPhee
Publisher: U. S. National Aeronautics & Space Administration
Published: 2009
Total Pages: 396
ISBN-13:
DOWNLOAD EBOOKDownload or read book Human Health and Performance Risks of Space Exploration Missions written by Jancy C. McPhee and published by U. S. National Aeronautics & Space Administration. This book was released on 2009 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author: National Research Council
Publisher: National Academies Press
Published: 2006-10-10
Total Pages: 104
ISBN-13: 030918066X
DOWNLOAD EBOOKFulfilling the President's Vision for Space Exploration (VSE) will require overcoming many challenges. Among these are the hazards of space radiation to crews traveling to the Moon and Mars. To explore these challenges in some depth and to examine ways to marshal research efforts to address them, NASA, NSF, and the NRC sponsored a workshop bringing together members of the space and planetary science, radiation physics, operations, and exploration engineering communities. The goals of the workshop were to increase understanding of the solar and space physics in the environment of Earth, the Moon, and Mars; to identify compelling relevant research goals; and discuss directions this research should take over the coming decade. This workshop report presents a discussion of radiation risks for the VSE, an assessment of specifying and predicting the space radiation environment, an analysis of operational strategies for space weather support, and a summary and conclusions of the workshop.
Download or read book Space Radiation Hazards and the Vision for Space Exploration written by National Research Council and published by National Academies Press. This book was released on 2006-10-10 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fulfilling the President's Vision for Space Exploration (VSE) will require overcoming many challenges. Among these are the hazards of space radiation to crews traveling to the Moon and Mars. To explore these challenges in some depth and to examine ways to marshal research efforts to address them, NASA, NSF, and the NRC sponsored a workshop bringing together members of the space and planetary science, radiation physics, operations, and exploration engineering communities. The goals of the workshop were to increase understanding of the solar and space physics in the environment of Earth, the Moon, and Mars; to identify compelling relevant research goals; and discuss directions this research should take over the coming decade. This workshop report presents a discussion of radiation risks for the VSE, an assessment of specifying and predicting the space radiation environment, an analysis of operational strategies for space weather support, and a summary and conclusions of the workshop.
Author: National Research Council
Publisher: National Academies Press
Published: 2006-11-10
Total Pages: 104
ISBN-13: 0309102642
DOWNLOAD EBOOKFulfilling the President's Vision for Space Exploration (VSE) will require overcoming many challenges. Among these are the hazards of space radiation to crews traveling to the Moon and Mars. To explore these challenges in some depth and to examine ways to marshal research efforts to address them, NASA, NSF, and the NRC sponsored a workshop bringing together members of the space and planetary science, radiation physics, operations, and exploration engineering communities. The goals of the workshop were to increase understanding of the solar and space physics in the environment of Earth, the Moon, and Mars; to identify compelling relevant research goals; and discuss directions this research should take over the coming decade. This workshop report presents a discussion of radiation risks for the VSE, an assessment of specifying and predicting the space radiation environment, an analysis of operational strategies for space weather support, and a summary and conclusions of the workshop.
Download or read book Space Radiation Hazards and the Vision for Space Exploration written by National Research Council and published by National Academies Press. This book was released on 2006-11-10 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fulfilling the President's Vision for Space Exploration (VSE) will require overcoming many challenges. Among these are the hazards of space radiation to crews traveling to the Moon and Mars. To explore these challenges in some depth and to examine ways to marshal research efforts to address them, NASA, NSF, and the NRC sponsored a workshop bringing together members of the space and planetary science, radiation physics, operations, and exploration engineering communities. The goals of the workshop were to increase understanding of the solar and space physics in the environment of Earth, the Moon, and Mars; to identify compelling relevant research goals; and discuss directions this research should take over the coming decade. This workshop report presents a discussion of radiation risks for the VSE, an assessment of specifying and predicting the space radiation environment, an analysis of operational strategies for space weather support, and a summary and conclusions of the workshop.
Author: National Aeronautics and Space Administration (NASA)
Publisher: Createspace Independent Publishing Platform
Published: 2018-06-03
Total Pages: 44
ISBN-13: 9781720618812
DOWNLOAD EBOOKThis document addresses calculations of probability distribution functions (PDFs) representing uncertainties in projecting fatal cancer risk from galactic cosmic rays (GCR) and solar particle events (SPEs). PDFs are used to test the effectiveness of potential radiation shielding approaches. Monte-Carlo techniques are used to propagate uncertainties in risk coefficients determined from epidemiology data, dose and dose-rate reduction factors, quality factors, and physics models of radiation environments. Competing mortality risks and functional correlations in radiation quality factor uncertainties are treated in the calculations. The cancer risk uncertainty is about four-fold for lunar and Mars mission risk projections. For short-stay lunar missins (180 d) lunar or Mars missions, GCR risks may exceed radiation risk limits. While shielding materials are marginally effective in reducing GCR cancer risks because of the penetrating nature of GCR and secondary radiation produced in tissue by relativisitc particles, polyethylene or carbon composite shielding cannot be shown to significantly reduce risk compared to aluminum shielding. Therefore, improving our knowledge of space radiobiology to narrow uncertainties that lead to wide PDFs is the best approach to ensure radiation protection goals are met for space exploration.Cucinotta, Francis A. and Kim, Myung-Hee Y. and Ren, LeiJohnson Space CenterBIOASTRONAUTICS; RADIOBIOLOGY; RADIATION DOSAGE; PROBABILITY DISTRIBUTION FUNCTIONS; CANCER; RADIATION HAZARDS; ASTRONAUTS; LUNAR EXPLORATION; MARS EXPLORATION; MANNED MARS MISSIONS; LONG DURATION SPACE FLIGHT; MANNED SPACE FLIGHT; RISK; RADIATION SHIELDING; MONTE CARLO METHOD
Download or read book Managing Lunar and Mars Mission Radiation Risks. Part 1; Cancer Risks, Uncertainties, and Shielding Effectiveness written by National Aeronautics and Space Administration (NASA) and published by Createspace Independent Publishing Platform. This book was released on 2018-06-03 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document addresses calculations of probability distribution functions (PDFs) representing uncertainties in projecting fatal cancer risk from galactic cosmic rays (GCR) and solar particle events (SPEs). PDFs are used to test the effectiveness of potential radiation shielding approaches. Monte-Carlo techniques are used to propagate uncertainties in risk coefficients determined from epidemiology data, dose and dose-rate reduction factors, quality factors, and physics models of radiation environments. Competing mortality risks and functional correlations in radiation quality factor uncertainties are treated in the calculations. The cancer risk uncertainty is about four-fold for lunar and Mars mission risk projections. For short-stay lunar missins (180 d) lunar or Mars missions, GCR risks may exceed radiation risk limits. While shielding materials are marginally effective in reducing GCR cancer risks because of the penetrating nature of GCR and secondary radiation produced in tissue by relativisitc particles, polyethylene or carbon composite shielding cannot be shown to significantly reduce risk compared to aluminum shielding. Therefore, improving our knowledge of space radiobiology to narrow uncertainties that lead to wide PDFs is the best approach to ensure radiation protection goals are met for space exploration.Cucinotta, Francis A. and Kim, Myung-Hee Y. and Ren, LeiJohnson Space CenterBIOASTRONAUTICS; RADIOBIOLOGY; RADIATION DOSAGE; PROBABILITY DISTRIBUTION FUNCTIONS; CANCER; RADIATION HAZARDS; ASTRONAUTS; LUNAR EXPLORATION; MARS EXPLORATION; MANNED MARS MISSIONS; LONG DURATION SPACE FLIGHT; MANNED SPACE FLIGHT; RISK; RADIATION SHIELDING; MONTE CARLO METHOD
Author: Task Group on the Biological Effects of Space Radiation
Publisher: National Academies Press
Published: 1997-03-13
Total Pages: 89
ISBN-13: 0309524296
DOWNLOAD EBOOKNASA's long-range plans include possible human exploratory missions to the moon and Mars within the next quarter century. Such missions beyond low Earth orbit will expose crews to transient radiation from solar particle events as well as continuous high-energy galactic cosmic rays ranging from energetic protons with low mean linear energy transfer (LET) to nuclei with high atomic numbers, high energies, and high LET. Because the radiation levels in space are high and the missions long, adequate shielding is needed to minimize the deleterious health effects of exposure to radiation. The knowledge base needed to design shielding involves two sets of factors, each with quantitative uncertainty?the radiation spectra and doses present behind different types of shielding, and the effects of the doses on relevant biological systems. It is only prudent to design shielding that will protect the crew of spacecraft exposed to predicted high, but uncertain, levels of radiation and biological effects. Because of the uncertainties regarding the degree and type of radiation protection needed, a requirement for shielding to protect against large deleterious, but uncertain, biological effects may be imposed, which in turn could result in an unacceptable cost to a mission. It therefore is of interest to reduce these uncertainties in biological effects and shielding requirements for reasons of mission feasibility, safety, and cost.
Download or read book Radiation Hazards to Crews of Interplanetary Missions written by Task Group on the Biological Effects of Space Radiation and published by National Academies Press. This book was released on 1997-03-13 with total page 89 pages. Available in PDF, EPUB and Kindle. Book excerpt: NASA's long-range plans include possible human exploratory missions to the moon and Mars within the next quarter century. Such missions beyond low Earth orbit will expose crews to transient radiation from solar particle events as well as continuous high-energy galactic cosmic rays ranging from energetic protons with low mean linear energy transfer (LET) to nuclei with high atomic numbers, high energies, and high LET. Because the radiation levels in space are high and the missions long, adequate shielding is needed to minimize the deleterious health effects of exposure to radiation. The knowledge base needed to design shielding involves two sets of factors, each with quantitative uncertainty?the radiation spectra and doses present behind different types of shielding, and the effects of the doses on relevant biological systems. It is only prudent to design shielding that will protect the crew of spacecraft exposed to predicted high, but uncertain, levels of radiation and biological effects. Because of the uncertainties regarding the degree and type of radiation protection needed, a requirement for shielding to protect against large deleterious, but uncertain, biological effects may be imposed, which in turn could result in an unacceptable cost to a mission. It therefore is of interest to reduce these uncertainties in biological effects and shielding requirements for reasons of mission feasibility, safety, and cost.
Author: National Academies of Sciences Engineering and Medicine
Publisher:
Published: 2022-03-24
Total Pages:
ISBN-13: 9780309479660
DOWNLOAD EBOOKAstronauts face unique health-related risks during crewed space missions, and longer-duration missions that extend to greater distances in our solar system (including to the Moon and Mars) will likely increase those risks. Cancer risks due to ionizing radiation exposure are one of these health-related risks. Assessing, managing, and communicating radiation-induced cancer risks associated with spaceflight are challenging because of incomplete knowledge of the radiation environment in space, limited data on radiation-induced cellular damage mechanisms, lack of direct observations from epidemiological studies, and the complexities of understanding radiation risk. At the request of the National Aeronautics and Space Administration (NASA), an ad hoc committee of the National Academies of Sciences, Engineering, and Medicine convened to provide advice on NASA's proposed updates to their space radiation health standard, which sets the allowable limit of space radiation exposure throughout the course of an astronaut's career. Space Radiation and Astronaut Health: Managing and Communicating Cancer Risks provides the committee's recommendations and conclusions regarding the updated space radiation health standard, NASA's radiation risk communication strategies, and a process for developing an ethics-informed waiver protocol for long-duration spaceflight missions.
Download or read book Space Radiation and Astronaut Health written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2022-03-24 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Astronauts face unique health-related risks during crewed space missions, and longer-duration missions that extend to greater distances in our solar system (including to the Moon and Mars) will likely increase those risks. Cancer risks due to ionizing radiation exposure are one of these health-related risks. Assessing, managing, and communicating radiation-induced cancer risks associated with spaceflight are challenging because of incomplete knowledge of the radiation environment in space, limited data on radiation-induced cellular damage mechanisms, lack of direct observations from epidemiological studies, and the complexities of understanding radiation risk. At the request of the National Aeronautics and Space Administration (NASA), an ad hoc committee of the National Academies of Sciences, Engineering, and Medicine convened to provide advice on NASA's proposed updates to their space radiation health standard, which sets the allowable limit of space radiation exposure throughout the course of an astronaut's career. Space Radiation and Astronaut Health: Managing and Communicating Cancer Risks provides the committee's recommendations and conclusions regarding the updated space radiation health standard, NASA's radiation risk communication strategies, and a process for developing an ethics-informed waiver protocol for long-duration spaceflight missions.
