Spatial Fleming-Viot Models with Selection and Mutation

Spatial Fleming-Viot Models with Selection and Mutation

Author: Donald A. Dawson

Publisher: Springer

Published: 2013-12-12

Total Pages: 866

ISBN-13: 3319021532

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This book constructs a rigorous framework for analysing selected phenomena in evolutionary theory of populations arising due to the combined effects of migration, selection and mutation in a spatial stochastic population model, namely the evolution towards fitter and fitter types through punctuated equilibria. The discussion is based on a number of new methods, in particular multiple scale analysis, nonlinear Markov processes and their entrance laws, atomic measure-valued evolutions and new forms of duality (for state-dependent mutation and multitype selection) which are used to prove ergodic theorems in this context and are applicable for many other questions and renormalization analysis for a variety of phenomena (stasis, punctuated equilibrium, failure of naive branching approximations, biodiversity) which occur due to the combination of rare mutation, mutation, resampling, migration and selection and make it necessary to mathematically bridge the gap (in the limit) between time and space scales.


Book Synopsis Spatial Fleming-Viot Models with Selection and Mutation by : Donald A. Dawson

Download or read book Spatial Fleming-Viot Models with Selection and Mutation written by Donald A. Dawson and published by Springer. This book was released on 2013-12-12 with total page 866 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constructs a rigorous framework for analysing selected phenomena in evolutionary theory of populations arising due to the combined effects of migration, selection and mutation in a spatial stochastic population model, namely the evolution towards fitter and fitter types through punctuated equilibria. The discussion is based on a number of new methods, in particular multiple scale analysis, nonlinear Markov processes and their entrance laws, atomic measure-valued evolutions and new forms of duality (for state-dependent mutation and multitype selection) which are used to prove ergodic theorems in this context and are applicable for many other questions and renormalization analysis for a variety of phenomena (stasis, punctuated equilibrium, failure of naive branching approximations, biodiversity) which occur due to the combination of rare mutation, mutation, resampling, migration and selection and make it necessary to mathematically bridge the gap (in the limit) between time and space scales.


Probability in Complex Physical Systems

Probability in Complex Physical Systems

Author: Jean-Dominique Deuschel

Publisher: Springer Science & Business Media

Published: 2012-04-23

Total Pages: 518

ISBN-13: 3642238114

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Probabilistic approaches have played a prominent role in the study of complex physical systems for more than thirty years. This volume collects twenty articles on various topics in this field, including self-interacting random walks and polymer models in random and non-random environments, branching processes, Parisi formulas and metastability in spin glasses, and hydrodynamic limits for gradient Gibbs models. The majority of these articles contain original results at the forefront of contemporary research; some of them include review aspects and summarize the state-of-the-art on topical issues – one focal point is the parabolic Anderson model, which is considered with various novel aspects including moving catalysts, acceleration and deceleration and fron propagation, for both time-dependent and time-independent potentials. The authors are among the world’s leading experts. This Festschrift honours two eminent researchers, Erwin Bolthausen and Jürgen Gärtner, whose scientific work has profoundly influenced the field and all of the present contributions.


Book Synopsis Probability in Complex Physical Systems by : Jean-Dominique Deuschel

Download or read book Probability in Complex Physical Systems written by Jean-Dominique Deuschel and published by Springer Science & Business Media. This book was released on 2012-04-23 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Probabilistic approaches have played a prominent role in the study of complex physical systems for more than thirty years. This volume collects twenty articles on various topics in this field, including self-interacting random walks and polymer models in random and non-random environments, branching processes, Parisi formulas and metastability in spin glasses, and hydrodynamic limits for gradient Gibbs models. The majority of these articles contain original results at the forefront of contemporary research; some of them include review aspects and summarize the state-of-the-art on topical issues – one focal point is the parabolic Anderson model, which is considered with various novel aspects including moving catalysts, acceleration and deceleration and fron propagation, for both time-dependent and time-independent potentials. The authors are among the world’s leading experts. This Festschrift honours two eminent researchers, Erwin Bolthausen and Jürgen Gärtner, whose scientific work has profoundly influenced the field and all of the present contributions.


Genealogies Of Interacting Particle Systems

Genealogies Of Interacting Particle Systems

Author: Matthias Birkner

Publisher: World Scientific

Published: 2020-02-24

Total Pages: 363

ISBN-13: 9811206104

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Interacting particle systems are Markov processes involving infinitely many interacting components. Since their introduction in the 1970s, researchers have found many applications in statistical physics and population biology. Genealogies, which follow the origin of the state of a site backwards in time, play an important role in their studies, especially for the biologically motivated systems.The program Genealogies of Interacting Particle Systems held at the Institute for Mathematical Sciences, National University of Singapore, from 17 July to 18 Aug 2017, brought together experts and young researchers interested in this modern topic. Central to the program were learning sessions where lecturers presented work outside of their own research, as well as a normal workshop. This is reflected in the present volume which contains two types of articles:Written by respected researchers, including experts in the field such as Steve Evans, member of the US National Academy of Sciences, as well as Anton Wakolbinger, Andreas Greven, and many others, this volume will no doubt be a valuable contribution to the probability community.


Book Synopsis Genealogies Of Interacting Particle Systems by : Matthias Birkner

Download or read book Genealogies Of Interacting Particle Systems written by Matthias Birkner and published by World Scientific. This book was released on 2020-02-24 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interacting particle systems are Markov processes involving infinitely many interacting components. Since their introduction in the 1970s, researchers have found many applications in statistical physics and population biology. Genealogies, which follow the origin of the state of a site backwards in time, play an important role in their studies, especially for the biologically motivated systems.The program Genealogies of Interacting Particle Systems held at the Institute for Mathematical Sciences, National University of Singapore, from 17 July to 18 Aug 2017, brought together experts and young researchers interested in this modern topic. Central to the program were learning sessions where lecturers presented work outside of their own research, as well as a normal workshop. This is reflected in the present volume which contains two types of articles:Written by respected researchers, including experts in the field such as Steve Evans, member of the US National Academy of Sciences, as well as Anton Wakolbinger, Andreas Greven, and many others, this volume will no doubt be a valuable contribution to the probability community.


Interacting Stochastic Systems

Interacting Stochastic Systems

Author: Jean-Dominique Deuschel

Publisher: Springer Science & Business Media

Published: 2005-12-05

Total Pages: 443

ISBN-13: 3540271104

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Core papers emanating from the research network, DFG-Schwerpunkt: Interacting stochastic systems of high complexity.


Book Synopsis Interacting Stochastic Systems by : Jean-Dominique Deuschel

Download or read book Interacting Stochastic Systems written by Jean-Dominique Deuschel and published by Springer Science & Business Media. This book was released on 2005-12-05 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: Core papers emanating from the research network, DFG-Schwerpunkt: Interacting stochastic systems of high complexity.


Issues in Logic, Probability, Combinatorics, and Chaos Theory: 2013 Edition

Issues in Logic, Probability, Combinatorics, and Chaos Theory: 2013 Edition

Author:

Publisher: ScholarlyEditions

Published: 2013-05-01

Total Pages: 1001

ISBN-13: 1490110127

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Issues in Logic, Probability, Combinatorics, and Chaos Theory: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Approximation Theory. The editors have built Issues in Logic, Probability, Combinatorics, and Chaos Theory: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Approximation Theory in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Logic, Probability, Combinatorics, and Chaos Theory: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.


Book Synopsis Issues in Logic, Probability, Combinatorics, and Chaos Theory: 2013 Edition by :

Download or read book Issues in Logic, Probability, Combinatorics, and Chaos Theory: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-05-01 with total page 1001 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Logic, Probability, Combinatorics, and Chaos Theory: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Approximation Theory. The editors have built Issues in Logic, Probability, Combinatorics, and Chaos Theory: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Approximation Theory in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Logic, Probability, Combinatorics, and Chaos Theory: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.


Mathematical Statistical Physics

Mathematical Statistical Physics

Author:

Publisher: Elsevier

Published: 2006-06-27

Total Pages: 849

ISBN-13: 0080479235

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The proceedings of the 2005 les Houches summer school on Mathematical Statistical Physics give and broad and clear overview on this fast developing area of interest to both physicists and mathematicians. Introduction to a field of math with many interdisciplinary connections in physics, biology, and computer science Roadmap to the next decade of mathematical statistical mechanics Volume for reference years to come


Book Synopsis Mathematical Statistical Physics by :

Download or read book Mathematical Statistical Physics written by and published by Elsevier. This book was released on 2006-06-27 with total page 849 pages. Available in PDF, EPUB and Kindle. Book excerpt: The proceedings of the 2005 les Houches summer school on Mathematical Statistical Physics give and broad and clear overview on this fast developing area of interest to both physicists and mathematicians. Introduction to a field of math with many interdisciplinary connections in physics, biology, and computer science Roadmap to the next decade of mathematical statistical mechanics Volume for reference years to come


Information Geometry and Population Genetics

Information Geometry and Population Genetics

Author: Julian Hofrichter

Publisher: Springer

Published: 2017-02-23

Total Pages: 323

ISBN-13: 3319520458

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The present monograph develops a versatile and profound mathematical perspective of the Wright--Fisher model of population genetics. This well-known and intensively studied model carries a rich and beautiful mathematical structure, which is uncovered here in a systematic manner. In addition to approaches by means of analysis, combinatorics and PDE, a geometric perspective is brought in through Amari's and Chentsov's information geometry. This concept allows us to calculate many quantities of interest systematically; likewise, the employed global perspective elucidates the stratification of the model in an unprecedented manner. Furthermore, the links to statistical mechanics and large deviation theory are explored and developed into powerful tools. Altogether, the manuscript provides a solid and broad working basis for graduate students and researchers interested in this field.


Book Synopsis Information Geometry and Population Genetics by : Julian Hofrichter

Download or read book Information Geometry and Population Genetics written by Julian Hofrichter and published by Springer. This book was released on 2017-02-23 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present monograph develops a versatile and profound mathematical perspective of the Wright--Fisher model of population genetics. This well-known and intensively studied model carries a rich and beautiful mathematical structure, which is uncovered here in a systematic manner. In addition to approaches by means of analysis, combinatorics and PDE, a geometric perspective is brought in through Amari's and Chentsov's information geometry. This concept allows us to calculate many quantities of interest systematically; likewise, the employed global perspective elucidates the stratification of the model in an unprecedented manner. Furthermore, the links to statistical mechanics and large deviation theory are explored and developed into powerful tools. Altogether, the manuscript provides a solid and broad working basis for graduate students and researchers interested in this field.


Metastability

Metastability

Author: Anton Bovier

Publisher: Springer

Published: 2016-02-11

Total Pages: 578

ISBN-13: 3319247778

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This monograph provides a concise presentation of a mathematical approach to metastability, a wide-spread phenomenon in the dynamics of non-linear systems - physical, chemical, biological or economic - subject to the action of temporal random forces typically referred to as noise, based on potential theory of reversible Markov processes. The authors shed new light on the metastability phenomenon as a sequence of visits of the path of the process to different metastable sets, and focuses on the precise analysis of the respective hitting probabilities and hitting times of these sets. The theory is illustrated with many examples, ranging from finite-state Markov chains, finite-dimensional diffusions and stochastic partial differential equations, via mean-field dynamics with and without disorder, to stochastic spin-flip and particle-hop dynamics and probabilistic cellular automata, unveiling the common universal features of these systems with respect to their metastable behaviour. The monograph will serve both as comprehensive introduction and as reference for graduate students and researchers interested in metastability.


Book Synopsis Metastability by : Anton Bovier

Download or read book Metastability written by Anton Bovier and published by Springer. This book was released on 2016-02-11 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph provides a concise presentation of a mathematical approach to metastability, a wide-spread phenomenon in the dynamics of non-linear systems - physical, chemical, biological or economic - subject to the action of temporal random forces typically referred to as noise, based on potential theory of reversible Markov processes. The authors shed new light on the metastability phenomenon as a sequence of visits of the path of the process to different metastable sets, and focuses on the precise analysis of the respective hitting probabilities and hitting times of these sets. The theory is illustrated with many examples, ranging from finite-state Markov chains, finite-dimensional diffusions and stochastic partial differential equations, via mean-field dynamics with and without disorder, to stochastic spin-flip and particle-hop dynamics and probabilistic cellular automata, unveiling the common universal features of these systems with respect to their metastable behaviour. The monograph will serve both as comprehensive introduction and as reference for graduate students and researchers interested in metastability.


Some Mathematical Models from Population Genetics

Some Mathematical Models from Population Genetics

Author: Alison Etheridge

Publisher: Springer

Published: 2011-01-05

Total Pages: 129

ISBN-13: 3642166326

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This work reflects sixteen hours of lectures delivered by the author at the 2009 St Flour summer school in probability. It provides a rapid introduction to a range of mathematical models that have their origins in theoretical population genetics. The models fall into two classes: forwards in time models for the evolution of frequencies of different genetic types in a population; and backwards in time (coalescent) models that trace out the genealogical relationships between individuals in a sample from the population. Some, like the classical Wright-Fisher model, date right back to the origins of the subject. Others, like the multiple merger coalescents or the spatial Lambda-Fleming-Viot process are much more recent. All share a rich mathematical structure. Biological terms are explained, the models are carefully motivated and tools for their study are presented systematically.


Book Synopsis Some Mathematical Models from Population Genetics by : Alison Etheridge

Download or read book Some Mathematical Models from Population Genetics written by Alison Etheridge and published by Springer. This book was released on 2011-01-05 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work reflects sixteen hours of lectures delivered by the author at the 2009 St Flour summer school in probability. It provides a rapid introduction to a range of mathematical models that have their origins in theoretical population genetics. The models fall into two classes: forwards in time models for the evolution of frequencies of different genetic types in a population; and backwards in time (coalescent) models that trace out the genealogical relationships between individuals in a sample from the population. Some, like the classical Wright-Fisher model, date right back to the origins of the subject. Others, like the multiple merger coalescents or the spatial Lambda-Fleming-Viot process are much more recent. All share a rich mathematical structure. Biological terms are explained, the models are carefully motivated and tools for their study are presented systematically.


Handbook of Statistical Genomics

Handbook of Statistical Genomics

Author: David J. Balding

Publisher: John Wiley & Sons

Published: 2019-07-09

Total Pages: 1828

ISBN-13: 1119429250

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A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.


Book Synopsis Handbook of Statistical Genomics by : David J. Balding

Download or read book Handbook of Statistical Genomics written by David J. Balding and published by John Wiley & Sons. This book was released on 2019-07-09 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.