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Stem Cell Biology and Regenerative Medicine in Ophthalmology

Author: Stephen Tsang

Publisher: Springer Science & Business Media

Published: 2012-12-09

Total Pages: 196

ISBN-13: 146145493X

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Patient specific and disease specific stem cell lines have already introduced groundbreaking advances into the research and practice of ophthalmology. This volume provides a comprehensive and engaging overview of the latest innovations in the field. Twelve chapters discuss the fastest growing areas in ophthalmological stem cell research, from disease modelling, drug screening and gene targeting to clinical genetics and regenerative treatments. Innovative results from stem cell research of the past decade are pointing the way toward practicable treatments for retinitis pigmentosa, age related macular degeneration, and Stargardt disease. What future directions will stem cell research take? Researchers, graduate students, and fellows alike will find food for thought in this insightful guide tapping into the collective knowledge of leaders in the field. Stem Cells in Ophthalmology is part of the Stem Cells in Regenerative Medicine series dedicated to discussing current challenges and future directions in stem cell research.

Book Synopsis Stem Cell Biology and Regenerative Medicine in Ophthalmology by : Stephen Tsang

Download or read book Stem Cell Biology and Regenerative Medicine in Ophthalmology written by Stephen Tsang and published by Springer Science & Business Media. This book was released on 2012-12-09 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patient specific and disease specific stem cell lines have already introduced groundbreaking advances into the research and practice of ophthalmology. This volume provides a comprehensive and engaging overview of the latest innovations in the field. Twelve chapters discuss the fastest growing areas in ophthalmological stem cell research, from disease modelling, drug screening and gene targeting to clinical genetics and regenerative treatments. Innovative results from stem cell research of the past decade are pointing the way toward practicable treatments for retinitis pigmentosa, age related macular degeneration, and Stargardt disease. What future directions will stem cell research take? Researchers, graduate students, and fellows alike will find food for thought in this insightful guide tapping into the collective knowledge of leaders in the field. Stem Cells in Ophthalmology is part of the Stem Cells in Regenerative Medicine series dedicated to discussing current challenges and future directions in stem cell research.

Regenerative Medicine and Stem Cell Therapy for the Eye

Author: Brian G. Ballios

Publisher: Springer

Published: 2019-02-18

Total Pages: 212

ISBN-13: 3319980807

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This book provides an overview of the types, sources, and applications of stem cells in regenerating various ocular tissues, with a perspective on both potential applications of stem cells and possible challenges. The scope of the chapters include both preclinical and clinical applications, including stem cell-derived therapies based on endogenous tissue repair; stem cell transplantation and cell replacement therapy; gene therapy; and in vitro disease modelling. Additionally, the volume presents applications in both anterior and posterior ocular disease, with a particular focus on diseases of the ocular surface, cornea, limbus, and retina, including inherited retinal dystrophies as well as acquired diseases, such as age-related macular degeneration. Regenerative Medicine and Stem Cell Therapy for the Eye is an ideal book for advanced researchers in stem cell and ocular biology as well as clinical ophthalmologists, and will be of interest to readers with backgrounds in developmental biology and bioengineering. This book also Skillfully reviews cutting-edge advances in stem cell biology as applied to regenerative medicine and ocular disease Provides expert viewpoints on key hurdles and challenges to successful implementation of stem cell-derived therapies in the clinical domain Offers a multi-disciplinary, broad understanding of cell-based therapies for ocular diseases by incorporating perspectives from biomedical scientists, physicians, and engineers Examines the connection between cell therapy and gene editing, in particular relation to ocular disease

Book Synopsis Regenerative Medicine and Stem Cell Therapy for the Eye by : Brian G. Ballios

Download or read book Regenerative Medicine and Stem Cell Therapy for the Eye written by Brian G. Ballios and published by Springer. This book was released on 2019-02-18 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the types, sources, and applications of stem cells in regenerating various ocular tissues, with a perspective on both potential applications of stem cells and possible challenges. The scope of the chapters include both preclinical and clinical applications, including stem cell-derived therapies based on endogenous tissue repair; stem cell transplantation and cell replacement therapy; gene therapy; and in vitro disease modelling. Additionally, the volume presents applications in both anterior and posterior ocular disease, with a particular focus on diseases of the ocular surface, cornea, limbus, and retina, including inherited retinal dystrophies as well as acquired diseases, such as age-related macular degeneration. Regenerative Medicine and Stem Cell Therapy for the Eye is an ideal book for advanced researchers in stem cell and ocular biology as well as clinical ophthalmologists, and will be of interest to readers with backgrounds in developmental biology and bioengineering. This book also Skillfully reviews cutting-edge advances in stem cell biology as applied to regenerative medicine and ocular disease Provides expert viewpoints on key hurdles and challenges to successful implementation of stem cell-derived therapies in the clinical domain Offers a multi-disciplinary, broad understanding of cell-based therapies for ocular diseases by incorporating perspectives from biomedical scientists, physicians, and engineers Examines the connection between cell therapy and gene editing, in particular relation to ocular disease

Stem Cells in Ophthalmology

Author: Daniel H. Scorsetti

Publisher: Jaypee Brothers Medical Publishers Pvt. Limited

Published: 2015-01-01

Total Pages: 0

ISBN-13: 9789962678762

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Stem Cells in Ophthalmology describes a wide range of therapeutic applications of stem cells in ophthalmological treatments. This book is written and edited by distinguished international authors, who have drawn heavily on their in-depth academic knowledge, practical experience and research. Comprised of 17 chapters, the book initially covers basic stem cell biology and immunity, proceeding to detail the use of stem cell therapy to regenerate all the structures of the visual system and ocular adnexa. Immunologic factors, such as antigen identification and functional rejection pathways are discussed in detail. The book also details practice of translational medicine and facilities, and governmental requirements needed to establish an ocular stem cell program. Stem Cells in Ophthalmology gives extensive coverage to the regenerative use of stem cells in ophthalmology. Enhanced by 84 colour images and illustrations, this is an essential resource for ophthalmologists and stem cell therapists. Key Features 84 full colour images and illustrations Covers all structures of the visual system in detail Edited by pan-American team of ophthalmology experts from Argentina, USA and Brazil

Book Synopsis Stem Cells in Ophthalmology by : Daniel H. Scorsetti

Download or read book Stem Cells in Ophthalmology written by Daniel H. Scorsetti and published by Jaypee Brothers Medical Publishers Pvt. Limited. This book was released on 2015-01-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cells in Ophthalmology describes a wide range of therapeutic applications of stem cells in ophthalmological treatments. This book is written and edited by distinguished international authors, who have drawn heavily on their in-depth academic knowledge, practical experience and research. Comprised of 17 chapters, the book initially covers basic stem cell biology and immunity, proceeding to detail the use of stem cell therapy to regenerate all the structures of the visual system and ocular adnexa. Immunologic factors, such as antigen identification and functional rejection pathways are discussed in detail. The book also details practice of translational medicine and facilities, and governmental requirements needed to establish an ocular stem cell program. Stem Cells in Ophthalmology gives extensive coverage to the regenerative use of stem cells in ophthalmology. Enhanced by 84 colour images and illustrations, this is an essential resource for ophthalmologists and stem cell therapists. Key Features 84 full colour images and illustrations Covers all structures of the visual system in detail Edited by pan-American team of ophthalmology experts from Argentina, USA and Brazil

The Eye

Author: Eman E. Taher

Publisher: Elsevier

Published: 2023-03-31

Total Pages: 309

ISBN-13: 0323983162

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The Eye, Volume Four, the latest release in the Stem Cell Innovation in Health and Disease series, addresses the recent data accumulated on the potential applications of stem cells to treat eye diseases. This volume highlights the recent development of cutting-edge in vitro and in vivo research tools and approaches, including human and murine organoid cultures, genetic editing in vitro and in vivo, human iPSC models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure eye diseases. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors in the field. This is a timely and fascinating collection of information and new discoveries that provides a contemporary snapshot album on the fast-moving field of regenerative medicine and stem cell therapeutics. Provides cutting-edge research to understand stem cell functions used in disease treatments of the eye Develops processes to bring stem cells from bench to bedside Includes up-to-date references on stem cell biology and function in common eye diseases and disorders

Book Synopsis The Eye by : Eman E. Taher

Download or read book The Eye written by Eman E. Taher and published by Elsevier. This book was released on 2023-03-31 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Eye, Volume Four, the latest release in the Stem Cell Innovation in Health and Disease series, addresses the recent data accumulated on the potential applications of stem cells to treat eye diseases. This volume highlights the recent development of cutting-edge in vitro and in vivo research tools and approaches, including human and murine organoid cultures, genetic editing in vitro and in vivo, human iPSC models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure eye diseases. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors in the field. This is a timely and fascinating collection of information and new discoveries that provides a contemporary snapshot album on the fast-moving field of regenerative medicine and stem cell therapeutics. Provides cutting-edge research to understand stem cell functions used in disease treatments of the eye Develops processes to bring stem cells from bench to bedside Includes up-to-date references on stem cell biology and function in common eye diseases and disorders

Pluripotent Stem Cells in Eye Disease Therapy

Author: Kapil Bharti

Publisher: Springer Nature

Published: 2019-10-25

Total Pages: 201

ISBN-13: 3030284719

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This book discusses applications of pluripotent stem cells to study eye disease in vitro and to create novel therapies for degenerative eye diseases. Chapters are contributed by experts in the field and cover such topics as the use of pluripotent stem cells in 2D and 3D engineering of ocular tissues for disease modelling and drug testing as well as approaches to replace degenerated RPE and photoreceptors in macular degeneration and retinitis pigmentosa. Pluripotent Stem Cells in Eye Disease Therapy presents a comprehensive discussion of basic science and clinical applications and is an indispensable resource for everyone from advanced graduate students to advanced professionals who want to learn about the potential of stem cell biology and its role in the field of retinal diseases.

Book Synopsis Pluripotent Stem Cells in Eye Disease Therapy by : Kapil Bharti

Download or read book Pluripotent Stem Cells in Eye Disease Therapy written by Kapil Bharti and published by Springer Nature. This book was released on 2019-10-25 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses applications of pluripotent stem cells to study eye disease in vitro and to create novel therapies for degenerative eye diseases. Chapters are contributed by experts in the field and cover such topics as the use of pluripotent stem cells in 2D and 3D engineering of ocular tissues for disease modelling and drug testing as well as approaches to replace degenerated RPE and photoreceptors in macular degeneration and retinitis pigmentosa. Pluripotent Stem Cells in Eye Disease Therapy presents a comprehensive discussion of basic science and clinical applications and is an indispensable resource for everyone from advanced graduate students to advanced professionals who want to learn about the potential of stem cell biology and its role in the field of retinal diseases.

Regenerative Biology of the Eye

Author: Alice Pébay

Publisher: Springer

Published: 2014-05-23

Total Pages: 310

ISBN-13: 1493907875

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This text is a comprehensive look at the current knowledge on stem cell application for vision loss, showcasing different types of stem cells (adult, embryonic, iPSCs) for diseases of the front and the back of the eye. It also highlights data obtained in various models from fish to human, as well as from the bionic eye project for vision regeneration. This volume in the Stem Cell Biology and Regenerative Medicine series is essential reading for stem cell biologists, ophthalmologists, advanced and graduate students, in addition to academics and medical staff who work in these disciplines.

Book Synopsis Regenerative Biology of the Eye by : Alice Pébay

Download or read book Regenerative Biology of the Eye written by Alice Pébay and published by Springer. This book was released on 2014-05-23 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is a comprehensive look at the current knowledge on stem cell application for vision loss, showcasing different types of stem cells (adult, embryonic, iPSCs) for diseases of the front and the back of the eye. It also highlights data obtained in various models from fish to human, as well as from the bionic eye project for vision regeneration. This volume in the Stem Cell Biology and Regenerative Medicine series is essential reading for stem cell biologists, ophthalmologists, advanced and graduate students, in addition to academics and medical staff who work in these disciplines.

Regenerative Medicine and Stem Cell Therapy for the Eye

Author: Brian G. Ballios

Publisher:

Published: 2018

Total Pages: 212

ISBN-13: 9783319980812

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Book Synopsis Regenerative Medicine and Stem Cell Therapy for the Eye by : Brian G. Ballios

Download or read book Regenerative Medicine and Stem Cell Therapy for the Eye written by Brian G. Ballios and published by . This book was released on 2018 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the types, sources, and applications of stem cells in regenerating various ocular tissues, with a perspective on both potential applications of stem cells and possible challenges. The scope of the chapters include both preclinical and clinical applications, including stem cell-derived therapies based on endogenous tissue repair; stem cell transplantation and cell replacement therapy; gene therapy; and in vitro disease modelling. Additionally, the volume presents applications in both anterior and posterior ocular disease, with a particular focus on diseases of the ocular surface, cornea, limbus, and retina, including inherited retinal dystrophies as well as acquired diseases, such as age-related macular degeneration. Regenerative Medicine and Stem Cell Therapy for the Eye is an ideal book for advanced researchers in stem cell and ocular biology as well as clinical ophthalmologists, and will be of interest to readers with backgrounds in developmental biology and bioengineering. This book also Skillfully reviews cutting-edge advances in stem cell biology as applied to regenerative medicine and ocular disease Provides expert viewpoints on key hurdles and challenges to successful implementation of stem cell-derived therapies in the clinical domain Offers a multi-disciplinary, broad understanding of cell-based therapies for ocular diseases by incorporating perspectives from biomedical scientists, physicians, and engineers Examines the connection between cell therapy and gene editing, in particular relation to ocular disease.

Cell-Based Therapy for Retinal Degenerative Disease

Author: R.P. Casaroli-Marano

Publisher: Karger Medical and Scientific Publishers

Published: 2014-04-22

Total Pages: 220

ISBN-13: 3318025852

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In this volume, some of the leading authorities present their exploration of applications of stem cell therapy to the treatment of major causes of blindness, including degenerative diseases and glaucoma. The diagnostic approach to patients, general concepts of cell-based therapy, immunological considerations, approaches to cell delivery (including engineered scaffolds), combined cell and gene therapy, nanomedicine applications to cell therapy and regulatory issues pertaining to manufacture and production are all considered in detail. The book serves as an excellent introduction to a field that is now entering early-stage clinical trials and promises to operate at the leading edge of regenerative medicine. Retina specialists, general ophthalmologists as well as researchers will find here a wealth of information on the translational aspects of cell-based therapies. Further, business executives and students interested in understanding the potential applications of stem cell therapy to retinal degenerative disease and glaucoma will also find this book informative reading.

Book Synopsis Cell-Based Therapy for Retinal Degenerative Disease by : R.P. Casaroli-Marano

Download or read book Cell-Based Therapy for Retinal Degenerative Disease written by R.P. Casaroli-Marano and published by Karger Medical and Scientific Publishers. This book was released on 2014-04-22 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume, some of the leading authorities present their exploration of applications of stem cell therapy to the treatment of major causes of blindness, including degenerative diseases and glaucoma. The diagnostic approach to patients, general concepts of cell-based therapy, immunological considerations, approaches to cell delivery (including engineered scaffolds), combined cell and gene therapy, nanomedicine applications to cell therapy and regulatory issues pertaining to manufacture and production are all considered in detail. The book serves as an excellent introduction to a field that is now entering early-stage clinical trials and promises to operate at the leading edge of regenerative medicine. Retina specialists, general ophthalmologists as well as researchers will find here a wealth of information on the translational aspects of cell-based therapies. Further, business executives and students interested in understanding the potential applications of stem cell therapy to retinal degenerative disease and glaucoma will also find this book informative reading.

Retinal and Optic Nerve Stem Cell Surgery

Author: Jeffrey N. Weiss

Publisher: Springer Nature

Published: 2020-11-19

Total Pages: 91

ISBN-13: 3030608506

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This is a concise how-to of successfully treating previously deemed "untreatable" retinal and optic nerve conditions with stem cell therapies. Based on the results of 11 years of experience treating approximately 600 patients, this text will serve as a template for others to develop similar stem cell based treatments in their specialty. Author, Jeffrey N. Weiss, MD is specifically poised to offer dependable insight on stem cell surgery for both the retina and the optic nerve, having performed the first retinal stem cell surgery in 2010, with Institutional Review Board (IRB) approved studies that are registered with the National Institute of Health (NIH), and listed on ClinicalTrials.gov. Featuring all original work from Dr. Jeffrey Weiss's specialization in stem cell ophthalmology, this book is primarily written for ophthalmologists, but structured so that specialists across disciplines can take the model presented and create their own studies and clinical trials using stem cell therapies.

Book Synopsis Retinal and Optic Nerve Stem Cell Surgery by : Jeffrey N. Weiss

Download or read book Retinal and Optic Nerve Stem Cell Surgery written by Jeffrey N. Weiss and published by Springer Nature. This book was released on 2020-11-19 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a concise how-to of successfully treating previously deemed "untreatable" retinal and optic nerve conditions with stem cell therapies. Based on the results of 11 years of experience treating approximately 600 patients, this text will serve as a template for others to develop similar stem cell based treatments in their specialty. Author, Jeffrey N. Weiss, MD is specifically poised to offer dependable insight on stem cell surgery for both the retina and the optic nerve, having performed the first retinal stem cell surgery in 2010, with Institutional Review Board (IRB) approved studies that are registered with the National Institute of Health (NIH), and listed on ClinicalTrials.gov. Featuring all original work from Dr. Jeffrey Weiss's specialization in stem cell ophthalmology, this book is primarily written for ophthalmologists, but structured so that specialists across disciplines can take the model presented and create their own studies and clinical trials using stem cell therapies.

Corneal Regeneration

Author: Jorge L. Alió

Publisher: Springer

Published: 2019-02-20

Total Pages: 507

ISBN-13: 3030013049

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This text provides expert instruction on the varying surgical techniques currently employed for the regeneration of the ocular surface. Corneal Regeneration: Therapy and Surgery begins with a thorough discussion of current research based on data obtained in clinical human studies, and discusses the potential clinical implications for this promising new stage of eye surgery. Sections devoted to the stem cell, regenerative surgery and therapy of the ocular surface epithelium, corneal stroma, and corneal endothelium follow, each section comprehensively covering applied anatomy, current therapy and regenerative techniques, with a look to future directions of the field including eventual cell therapy. Corneal Regeneration: Therapy and Surgery is the first book of its kind, systematically covering the developments the medical community has achieved in corneal regeneration from all angles. Written and edited by leading experts in the field, researchers and ophthalmologists alike will find this to be a unique source of information on corneal regeneration, as well as a thoughtful reflection on potential applications of regenerative surgery in ophthalmology as a whole.

Book Synopsis Corneal Regeneration by : Jorge L. Alió

Download or read book Corneal Regeneration written by Jorge L. Alió and published by Springer. This book was released on 2019-02-20 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides expert instruction on the varying surgical techniques currently employed for the regeneration of the ocular surface. Corneal Regeneration: Therapy and Surgery begins with a thorough discussion of current research based on data obtained in clinical human studies, and discusses the potential clinical implications for this promising new stage of eye surgery. Sections devoted to the stem cell, regenerative surgery and therapy of the ocular surface epithelium, corneal stroma, and corneal endothelium follow, each section comprehensively covering applied anatomy, current therapy and regenerative techniques, with a look to future directions of the field including eventual cell therapy. Corneal Regeneration: Therapy and Surgery is the first book of its kind, systematically covering the developments the medical community has achieved in corneal regeneration from all angles. Written and edited by leading experts in the field, researchers and ophthalmologists alike will find this to be a unique source of information on corneal regeneration, as well as a thoughtful reflection on potential applications of regenerative surgery in ophthalmology as a whole.