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Streptococcal Superantigens

Author: Anshu Babbar

Publisher: Springer

Published: 2015-07-24

Total Pages: 51

ISBN-13: 3319224557

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This book provides ample knowledge and better understanding of Streptococcus pyogenes and their superantigens. Many illustrations make this a highly informative book. This book elucidates briefly Streptococcus pyogenes as a strict human pathogen possessing an array of virulence factors. These help in evading host immune responses such as by the activation of non-specific T-cell subpopulations by producing superantigens. This book mainly focuses on streptococcal superantigens and explains how they are different from conventional antigens. Moreover, it elaborates those diseases in which superantigens are actively involved. Useful aspects of superantigens and different therapeutic interventions to eradicate superantigens induced diseased are also discussed.

Book Synopsis Streptococcal Superantigens by : Anshu Babbar

Download or read book Streptococcal Superantigens written by Anshu Babbar and published by Springer. This book was released on 2015-07-24 with total page 51 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides ample knowledge and better understanding of Streptococcus pyogenes and their superantigens. Many illustrations make this a highly informative book. This book elucidates briefly Streptococcus pyogenes as a strict human pathogen possessing an array of virulence factors. These help in evading host immune responses such as by the activation of non-specific T-cell subpopulations by producing superantigens. This book mainly focuses on streptococcal superantigens and explains how they are different from conventional antigens. Moreover, it elaborates those diseases in which superantigens are actively involved. Useful aspects of superantigens and different therapeutic interventions to eradicate superantigens induced diseased are also discussed.

Necrotizing Soft Tissue Infections

Author: Anna Norrby-Teglund

Publisher: Springer Nature

Published: 2020-10-20

Total Pages: 212

ISBN-13: 3030576167

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This volume aims to enhance the current understanding of clinical features, treatment and pathogenic aspects in necrotizing soft tissue infections. Various representative case studies are discussed to enhance the readers’ understanding of these complex diseases. Necrotizing soft tissue infections are rapidly spreading infections that may cause extensive soft tissue or limb loss, multiorgan failure and are associated with a considerable fatality rate. It is undisputed that rapid diagnosis and prompt intervention is directly related to survival. The initial presentation may be limited to unspecific symptoms such as tenderness, swelling, erythema and pain. Thus, diagnosis and management are challenging due to heterogeneity in clinical presentation, in co-morbidities, in microbiological aetiology, as well as in the pathogenic mechanisms. An international and multidisciplinary consortium, INFECT, has for the last 6 years been pursuing research aimed to advance the understanding of the clinical and pathogenic aspects of these infections. A central part has been to create a comprehensive clinical registry and associated biobank which have also formed the basis for the experimental studies. Using the INFECT patient cohort, as well as an integrated systems biology approach in patients and clinically relevant experimental models, an advanced insight of diagnostic features, causative microbial agents, treatment strategies, and pathogenic mechanisms (host and bacterial disease traits and their underlying interaction network) has been obtained.

Book Synopsis Necrotizing Soft Tissue Infections by : Anna Norrby-Teglund

Download or read book Necrotizing Soft Tissue Infections written by Anna Norrby-Teglund and published by Springer Nature. This book was released on 2020-10-20 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume aims to enhance the current understanding of clinical features, treatment and pathogenic aspects in necrotizing soft tissue infections. Various representative case studies are discussed to enhance the readers’ understanding of these complex diseases. Necrotizing soft tissue infections are rapidly spreading infections that may cause extensive soft tissue or limb loss, multiorgan failure and are associated with a considerable fatality rate. It is undisputed that rapid diagnosis and prompt intervention is directly related to survival. The initial presentation may be limited to unspecific symptoms such as tenderness, swelling, erythema and pain. Thus, diagnosis and management are challenging due to heterogeneity in clinical presentation, in co-morbidities, in microbiological aetiology, as well as in the pathogenic mechanisms. An international and multidisciplinary consortium, INFECT, has for the last 6 years been pursuing research aimed to advance the understanding of the clinical and pathogenic aspects of these infections. A central part has been to create a comprehensive clinical registry and associated biobank which have also formed the basis for the experimental studies. Using the INFECT patient cohort, as well as an integrated systems biology approach in patients and clinically relevant experimental models, an advanced insight of diagnostic features, causative microbial agents, treatment strategies, and pathogenic mechanisms (host and bacterial disease traits and their underlying interaction network) has been obtained.

Superantigens

Author: Leung

Publisher: CRC Press

Published: 1997-02-20

Total Pages: 626

ISBN-13: 9780824798130

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This up-to-date sourcebook covers viral and bacterial superantigens (SAgs) from molecular structure and immunological processes to pathology and treatment of superantigen-mediated human diseases. Discusses diseases beyond Toxic Shock Syndrome, such as autoimmune and inflammatory skin conditions, as well as the role of superantigens in other infectious diseases. Illustrated with molecular structures of superantigens.

Book Synopsis Superantigens by : Leung

Download or read book Superantigens written by Leung and published by CRC Press. This book was released on 1997-02-20 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-date sourcebook covers viral and bacterial superantigens (SAgs) from molecular structure and immunological processes to pathology and treatment of superantigen-mediated human diseases. Discusses diseases beyond Toxic Shock Syndrome, such as autoimmune and inflammatory skin conditions, as well as the role of superantigens in other infectious diseases. Illustrated with molecular structures of superantigens.

Addressing Emerging Infectious Disease Threats

Author:

Publisher:

Published: 1994

Total Pages: 56

ISBN-13:

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This plan addresses the need to improve our ability to identify infectious disease threats and respond to them effectively by improving the public health infrastructure at the local, state and federal levels. The goals of the plan are surveillance (detect, promptly investigate, and monitor emerging pathogens, the diseases they cause, and the factors influencing their emergence); applied research (integrate laboratory science and epidemiology to optimize public health practice); prevention and control (enhance communication of public health information about emerging diseases and ensure prompt implementation of prevention strategies); and infrastructure (strengthen local, state, and federal public health infrastructures to support surveillance and implement prevention and control programs).

Book Synopsis Addressing Emerging Infectious Disease Threats by :

Download or read book Addressing Emerging Infectious Disease Threats written by and published by . This book was released on 1994 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: This plan addresses the need to improve our ability to identify infectious disease threats and respond to them effectively by improving the public health infrastructure at the local, state and federal levels. The goals of the plan are surveillance (detect, promptly investigate, and monitor emerging pathogens, the diseases they cause, and the factors influencing their emergence); applied research (integrate laboratory science and epidemiology to optimize public health practice); prevention and control (enhance communication of public health information about emerging diseases and ensure prompt implementation of prevention strategies); and infrastructure (strengthen local, state, and federal public health infrastructures to support surveillance and implement prevention and control programs).

Bacterial Superantigens

Author: Jacques Thibodeau

Publisher:

Published: 1995

Total Pages: 272

ISBN-13:

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Although the field of superantigens (SAgs) has boomed in recent years, the function of these proteins in bacterial infection remains elusive. This volume begins with a brief introduction, followed by 15 chapters. Among the topics are structural studies of streptococcal pyrogenic exotoxin superantigens; Yersinia infection--the virulence determinants and SAgs they produce; structural features of T cell receptor recognition of SAgs; the pathophysiology of bacterial SAgs in vivo; and antibody targeted SAgs in experimental tumor therapy. Annotation copyright by Book News, Inc., Portland, OR

Book Synopsis Bacterial Superantigens by : Jacques Thibodeau

Download or read book Bacterial Superantigens written by Jacques Thibodeau and published by . This book was released on 1995 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the field of superantigens (SAgs) has boomed in recent years, the function of these proteins in bacterial infection remains elusive. This volume begins with a brief introduction, followed by 15 chapters. Among the topics are structural studies of streptococcal pyrogenic exotoxin superantigens; Yersinia infection--the virulence determinants and SAgs they produce; structural features of T cell receptor recognition of SAgs; the pathophysiology of bacterial SAgs in vivo; and antibody targeted SAgs in experimental tumor therapy. Annotation copyright by Book News, Inc., Portland, OR

Streptococci and the Host

Author: Thea Horaud

Publisher: Springer Science & Business Media

Published: 2013-11-08

Total Pages: 939

ISBN-13: 1489918256

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Streptococci and enterococci are the etiologic agents of infectious diseases that rank among the most severe in human pathology. The diagnosis, antibiotherapy, and prevention of the streptococcal diseases have improved considerably. However, the reemergence of severe streptococcal and enterococcal diseases constitutes a growing public health con cern, which remains open to scientific and medical debate. The XIII'h Lancefield International Symposium on Streptococci and Streptococcal Diseases, held at Institut Pasteur, Paris, France, September 16---2el, 1996, attracted 505 par ticipants from 43 countries. Twenty-two percent of the participants were students, a clear sign of the intense interest in this field. Of the 390 presentations made at the symposium, 260 were submitted as manuscripts for the Proceedings; we have included 249 of these in this volume. This symposium provided a forum for the presentation of the most recent findings and approaches to understanding several important fields, such as new aspects of infec tion, bacteria~host interactions, epidemiology, and molecular genetics of streptococci and enterococci. Over the last three years, the study of these subjects has expanded as increas ingly sophisticated methods of molecular analysis have been applied to investigate the bi ology of pathogenic streptococci and enterococci. Virulence, vaccine strategies, genetics, antibiotic resistance, epidemiology, and immunology are now being examined through the lens of molecular biology. The application of recently developed techniques to this field will continue to yield insight into the mechanism by which these organisms cause disease.

Book Synopsis Streptococci and the Host by : Thea Horaud

Download or read book Streptococci and the Host written by Thea Horaud and published by Springer Science & Business Media. This book was released on 2013-11-08 with total page 939 pages. Available in PDF, EPUB and Kindle. Book excerpt: Streptococci and enterococci are the etiologic agents of infectious diseases that rank among the most severe in human pathology. The diagnosis, antibiotherapy, and prevention of the streptococcal diseases have improved considerably. However, the reemergence of severe streptococcal and enterococcal diseases constitutes a growing public health con cern, which remains open to scientific and medical debate. The XIII'h Lancefield International Symposium on Streptococci and Streptococcal Diseases, held at Institut Pasteur, Paris, France, September 16---2el, 1996, attracted 505 par ticipants from 43 countries. Twenty-two percent of the participants were students, a clear sign of the intense interest in this field. Of the 390 presentations made at the symposium, 260 were submitted as manuscripts for the Proceedings; we have included 249 of these in this volume. This symposium provided a forum for the presentation of the most recent findings and approaches to understanding several important fields, such as new aspects of infec tion, bacteria~host interactions, epidemiology, and molecular genetics of streptococci and enterococci. Over the last three years, the study of these subjects has expanded as increas ingly sophisticated methods of molecular analysis have been applied to investigate the bi ology of pathogenic streptococci and enterococci. Virulence, vaccine strategies, genetics, antibiotic resistance, epidemiology, and immunology are now being examined through the lens of molecular biology. The application of recently developed techniques to this field will continue to yield insight into the mechanism by which these organisms cause disease.

Streptococcal Infections

Author: Dennis L. Stevens

Publisher: Oxford University Press, USA

Published: 2000

Total Pages: 474

ISBN-13: 9780195099218

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Streptococcal Infections: Clinical Aspects, Microbiology, and Molecular Pathogenesis offers an in-depth examination of the spectrum of hemolytic streptococcal infections and their complications. Additionally, the volume incorporates and discusses aspects of pneumococcal, entrococcal, and oral streptococcal disease. The recent resurgence of rheumatic fever, concomitant outbreaks of severe systemic group A streptococcal infections (often accompanied by toxic shock), an increasing incidence of multiple antibiotic resistance among streptococcal species, and an intensified effort to develop effective streptococcal vaccines have brought renewed attention to the continuing role of streptococci for causing significant medical and public health problems in both industrialized and developing countries. Addressing clinical and epidemiological aspects, and microbiological and other approaches of the research scientist, this volume is the first to comprehensively address these clinically important organisms in many years. The contributors are internationally recognized for their expertise, making this book invaluable for infectious disease physicians, (internists, pediatricians, and family physicians, microbiologists, epidemiologists, and basic scientists with an interest in streptococcal infections and their complications.

Book Synopsis Streptococcal Infections by : Dennis L. Stevens

Download or read book Streptococcal Infections written by Dennis L. Stevens and published by Oxford University Press, USA. This book was released on 2000 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Streptococcal Infections: Clinical Aspects, Microbiology, and Molecular Pathogenesis offers an in-depth examination of the spectrum of hemolytic streptococcal infections and their complications. Additionally, the volume incorporates and discusses aspects of pneumococcal, entrococcal, and oral streptococcal disease. The recent resurgence of rheumatic fever, concomitant outbreaks of severe systemic group A streptococcal infections (often accompanied by toxic shock), an increasing incidence of multiple antibiotic resistance among streptococcal species, and an intensified effort to develop effective streptococcal vaccines have brought renewed attention to the continuing role of streptococci for causing significant medical and public health problems in both industrialized and developing countries. Addressing clinical and epidemiological aspects, and microbiological and other approaches of the research scientist, this volume is the first to comprehensively address these clinically important organisms in many years. The contributors are internationally recognized for their expertise, making this book invaluable for infectious disease physicians, (internists, pediatricians, and family physicians, microbiologists, epidemiologists, and basic scientists with an interest in streptococcal infections and their complications.

Superantigens and Superallergens

Author: Gianni Marone

Publisher: Karger Medical and Scientific Publishers

Published: 2007-01-01

Total Pages: 259

ISBN-13: 3805582668

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Superantigens constitute a growing family of bacterial and viral proteins that share the capacity of inducing massive activation of the immune system. This volume contains contributions from leaders in the field of classical T cell superantigens and sheds light on relevant B cell superantigens at the molecular and biochemical levels. This is the first volume to put together basic and clinical aspects of the classical T cell superantigens, B cell superantigens and superallergens. It will therefore be indispensable reading to basic and clinical immunologists, microbiologists, virologists and specialists in allergic and immune disorders.

Book Synopsis Superantigens and Superallergens by : Gianni Marone

Download or read book Superantigens and Superallergens written by Gianni Marone and published by Karger Medical and Scientific Publishers. This book was released on 2007-01-01 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Superantigens constitute a growing family of bacterial and viral proteins that share the capacity of inducing massive activation of the immune system. This volume contains contributions from leaders in the field of classical T cell superantigens and sheds light on relevant B cell superantigens at the molecular and biochemical levels. This is the first volume to put together basic and clinical aspects of the classical T cell superantigens, B cell superantigens and superallergens. It will therefore be indispensable reading to basic and clinical immunologists, microbiologists, virologists and specialists in allergic and immune disorders.

Wound Healing and Skin Physiology

Author: Peter Altmeyer

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 701

ISBN-13: 3642778828

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On the occasion of the European Congress on Wound Healing and Skin Physiology (Bochum, Germany, November 1992), an international team of scientists and clinicians discussed the core topics in this important field of dermatological and surgical research. Themes include morphology and physiology, microcirculation and angiogenesis, biochemistry and immunology, microbiology and wound infection, non-invasive measurement techniques, wound repair, surgical treatment, dressings, and agents that promote wound healing.

Book Synopsis Wound Healing and Skin Physiology by : Peter Altmeyer

Download or read book Wound Healing and Skin Physiology written by Peter Altmeyer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: On the occasion of the European Congress on Wound Healing and Skin Physiology (Bochum, Germany, November 1992), an international team of scientists and clinicians discussed the core topics in this important field of dermatological and surgical research. Themes include morphology and physiology, microcirculation and angiogenesis, biochemistry and immunology, microbiology and wound infection, non-invasive measurement techniques, wound repair, surgical treatment, dressings, and agents that promote wound healing.

Acute Rheumatic Fever and Rheumatic Heart Disease

Author: Dr. Scott Dougherty

Publisher: Elsevier Health Sciences

Published: 2020-02-22

Total Pages: 364

ISBN-13: 0323754600

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Acute Rheumatic Fever and Rheumatic Heart Disease is a concise, yet comprehensive, clinical resource highlighting must-know information on rheumatic heart disease and acute rheumatic fever from a global perspective. Covering the major issues dominating the field, this practical resource presents sufficient detail for a deep and thorough understanding of the latest treatment options, potential complications, and disease management strategies to improve patient outcomes. Divided into four distinct sections for ease of navigation: Acute Rheumatic Fever, Rheumatic Heart Disease, Population-Based Strategies for Disease Control, and Acute and Emergency Presentations. International editors and chapter authors ensure a truly global perspective. Covers all clinical aspects, including epidemiology, pathophysiology, clinical features, diagnosis, management, and treatment. Includes key topics on population-based measures for disease control for effective primary, secondary, and tertiary prevention. Consolidates today’s available information and guidance into a single, convenient resource.

Book Synopsis Acute Rheumatic Fever and Rheumatic Heart Disease by : Dr. Scott Dougherty

Download or read book Acute Rheumatic Fever and Rheumatic Heart Disease written by Dr. Scott Dougherty and published by Elsevier Health Sciences. This book was released on 2020-02-22 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute Rheumatic Fever and Rheumatic Heart Disease is a concise, yet comprehensive, clinical resource highlighting must-know information on rheumatic heart disease and acute rheumatic fever from a global perspective. Covering the major issues dominating the field, this practical resource presents sufficient detail for a deep and thorough understanding of the latest treatment options, potential complications, and disease management strategies to improve patient outcomes. Divided into four distinct sections for ease of navigation: Acute Rheumatic Fever, Rheumatic Heart Disease, Population-Based Strategies for Disease Control, and Acute and Emergency Presentations. International editors and chapter authors ensure a truly global perspective. Covers all clinical aspects, including epidemiology, pathophysiology, clinical features, diagnosis, management, and treatment. Includes key topics on population-based measures for disease control for effective primary, secondary, and tertiary prevention. Consolidates today’s available information and guidance into a single, convenient resource.