Structure and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles

Structure and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles

Author: Max L. Birnstiel

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 221

ISBN-13: 3642730205

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In the past decade a most interesting story of the role played by the small nuclear RNPs, catalysts in RNA processing, has unfolded. Early investigations of the structure of these particles gave rise to hypotheses of their functions. As described in this book, these have been confirmed or are being tested by biochemical ex perimentation and most recently by the powerful technique of genetic analysis. Both biochemical and genetical approaches will also determine to what degree, and how, snRNPs and their cofactors participate in the differential expression of genes. As the details emerge and the number of snRNP species increases way beyond the six initially identified, one feels at the threshold of even greater things to come. The book covers many results in one of the most rapidly expanding fields of molecular biology. For this reason alone the specialist may detect some omissions and shortcomings. I hope they will be few. Instead of presenting a collation of conference reports with much overlap between them, this book has been written specially for the purpose of surveying the literature up to early 1987 in the snRNP field in a coherent manner, each of the seven chapters having been produced by connoisseurs of their field. While not each and every snRNP story can be covered in such a book, I hope that it will provide enjoyable and stimulating reading.


Book Synopsis Structure and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles by : Max L. Birnstiel

Download or read book Structure and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles written by Max L. Birnstiel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade a most interesting story of the role played by the small nuclear RNPs, catalysts in RNA processing, has unfolded. Early investigations of the structure of these particles gave rise to hypotheses of their functions. As described in this book, these have been confirmed or are being tested by biochemical ex perimentation and most recently by the powerful technique of genetic analysis. Both biochemical and genetical approaches will also determine to what degree, and how, snRNPs and their cofactors participate in the differential expression of genes. As the details emerge and the number of snRNP species increases way beyond the six initially identified, one feels at the threshold of even greater things to come. The book covers many results in one of the most rapidly expanding fields of molecular biology. For this reason alone the specialist may detect some omissions and shortcomings. I hope they will be few. Instead of presenting a collation of conference reports with much overlap between them, this book has been written specially for the purpose of surveying the literature up to early 1987 in the snRNP field in a coherent manner, each of the seven chapters having been produced by connoisseurs of their field. While not each and every snRNP story can be covered in such a book, I hope that it will provide enjoyable and stimulating reading.


Small Nuclear Ribonucleoprotein Particles

Small Nuclear Ribonucleoprotein Particles

Author: Eugenia A. Saba

Publisher:

Published: 1991

Total Pages: 98

ISBN-13:

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Book Synopsis Small Nuclear Ribonucleoprotein Particles by : Eugenia A. Saba

Download or read book Small Nuclear Ribonucleoprotein Particles written by Eugenia A. Saba and published by . This book was released on 1991 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt:


The Nucleolus

The Nucleolus

Author: Mark O. J. Olson

Publisher: Springer Science & Business Media

Published: 2004-08-03

Total Pages: 370

ISBN-13: 9780306478734

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As the first comprehensive overview of the nucleolus since 1985, The Nucleolus covers our current understanding of the cell nucleolus, including its role in ribosome assembly and its additional newly-discovered activities. The eighteen chapters have been written by experts who are actively engaged in research on the nucleolus and have an in depth review of the following topics: - nucleolar ultrastructure and dynamics, - behavior during mitosis, - ribosomal DNA gene and chromatin structure, - pre-ribosomal RNA transcription, - processing and modification, - ribosome assembly, - small nucleolar RNAs, - proteomics and non-traditional functions of the nucleolus. Separate chapters are also provided for yeast and higher eukaryotes on many topics. The Nucleolus will appeal not only to scientists directly engaged in nucleolar research, but also those working in related areas such as gene expression, protein biosynthesis, ribosome structure, transcription, chromatin structure, molecular genetics and the structure and functions of the cell nucleus in general.


Book Synopsis The Nucleolus by : Mark O. J. Olson

Download or read book The Nucleolus written by Mark O. J. Olson and published by Springer Science & Business Media. This book was released on 2004-08-03 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the first comprehensive overview of the nucleolus since 1985, The Nucleolus covers our current understanding of the cell nucleolus, including its role in ribosome assembly and its additional newly-discovered activities. The eighteen chapters have been written by experts who are actively engaged in research on the nucleolus and have an in depth review of the following topics: - nucleolar ultrastructure and dynamics, - behavior during mitosis, - ribosomal DNA gene and chromatin structure, - pre-ribosomal RNA transcription, - processing and modification, - ribosome assembly, - small nucleolar RNAs, - proteomics and non-traditional functions of the nucleolus. Separate chapters are also provided for yeast and higher eukaryotes on many topics. The Nucleolus will appeal not only to scientists directly engaged in nucleolar research, but also those working in related areas such as gene expression, protein biosynthesis, ribosome structure, transcription, chromatin structure, molecular genetics and the structure and functions of the cell nucleus in general.


Nuclear Structure and Function

Nuclear Structure and Function

Author: Miguel Berrios

Publisher: Academic Press

Published: 1998

Total Pages: 659

ISBN-13: 0125641559

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This volume is a comprehensive guide to the methodologies used in the study of structural domains of cell nuclei. The text covers chromatin, the karyoskeleton, the soluble domain, and the nucleolus. It details methods that are used to isolate components from these domains and techniques used to assemble and disassemble nuclear elements. There is also coverage of three-dimensional mapping and localization of nuclear processes. Key Features * Provides a practical laboratory guide for studying cell nuclei * Includes comprehensive and easy-to-follow protocols


Book Synopsis Nuclear Structure and Function by : Miguel Berrios

Download or read book Nuclear Structure and Function written by Miguel Berrios and published by Academic Press. This book was released on 1998 with total page 659 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a comprehensive guide to the methodologies used in the study of structural domains of cell nuclei. The text covers chromatin, the karyoskeleton, the soluble domain, and the nucleolus. It details methods that are used to isolate components from these domains and techniques used to assemble and disassemble nuclear elements. There is also coverage of three-dimensional mapping and localization of nuclear processes. Key Features * Provides a practical laboratory guide for studying cell nuclei * Includes comprehensive and easy-to-follow protocols


Structure of Antigens

Structure of Antigens

Author: Marc H. V. Van Regenmortel

Publisher: CRC Press

Published: 1992-12-07

Total Pages: 404

ISBN-13: 9780849388675

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Structure of Antigens discusses a variety of topics dealing with the structural basis of antigenicity. Topics include the analytical methods used to elucidate the structure of antigens, the structure of antibodies, the principles underlying modern immunoassays and the measurement of antibody binding affinity, and physicochemical principles and methodological aspects. The book also considers major groups of antigens distinguished by their functional activity and biological role (e.g., drugs, autoantigens, snake toxins, allergens) or by their association with particular biological systems (e.g., antigens of microorganisms). Structure of Antigens will provide a current, useful, reference for researchers and graduate students in all fields of biological science who need an overview of antigenic specificity. VOLUME II


Book Synopsis Structure of Antigens by : Marc H. V. Van Regenmortel

Download or read book Structure of Antigens written by Marc H. V. Van Regenmortel and published by CRC Press. This book was released on 1992-12-07 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structure of Antigens discusses a variety of topics dealing with the structural basis of antigenicity. Topics include the analytical methods used to elucidate the structure of antigens, the structure of antibodies, the principles underlying modern immunoassays and the measurement of antibody binding affinity, and physicochemical principles and methodological aspects. The book also considers major groups of antigens distinguished by their functional activity and biological role (e.g., drugs, autoantigens, snake toxins, allergens) or by their association with particular biological systems (e.g., antigens of microorganisms). Structure of Antigens will provide a current, useful, reference for researchers and graduate students in all fields of biological science who need an overview of antigenic specificity. VOLUME II


The Eukaryotic Nucleus

The Eukaryotic Nucleus

Author: Samuel H. Wilson

Publisher: CRC Press

Published: 1990-08-09

Total Pages: 476

ISBN-13: 9780936923338

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This series provides, in two volumes, a complete and exhaustive review of the subject of the eukaryotic nucleus, the site of the DNA. The focus of the book is how the information in the DNA is transcribed, accessed and maintained.


Book Synopsis The Eukaryotic Nucleus by : Samuel H. Wilson

Download or read book The Eukaryotic Nucleus written by Samuel H. Wilson and published by CRC Press. This book was released on 1990-08-09 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series provides, in two volumes, a complete and exhaustive review of the subject of the eukaryotic nucleus, the site of the DNA. The focus of the book is how the information in the DNA is transcribed, accessed and maintained.


Alternative Splicing and Cancer

Alternative Splicing and Cancer

Author: Muzafar A. Macha

Publisher: CRC Press

Published: 2024-05-03

Total Pages: 264

ISBN-13: 1040030688

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This book Alternative Splicing and Cancer explores the crucial role alternative splicing, a post-transcriptional process, plays in human health and diseases, particularly cancer. Diving deep into the complexities of gene expression and protein diversity, the book illuminates how abnormal splicing contributes to aggressive tumor formation, affecting cellular functions such as proliferation, survival, and immune evasion. With a focus on understanding molecular mechanisms, this book unravels potential diagnostic and prognostic targets, opening doors for enhanced anti-cancer treatment efficacy. An indispensable resource for anyone intrigued by the interplay between gene splicing and cancer biology, it paves the way towards innovative therapeutic strategies.


Book Synopsis Alternative Splicing and Cancer by : Muzafar A. Macha

Download or read book Alternative Splicing and Cancer written by Muzafar A. Macha and published by CRC Press. This book was released on 2024-05-03 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book Alternative Splicing and Cancer explores the crucial role alternative splicing, a post-transcriptional process, plays in human health and diseases, particularly cancer. Diving deep into the complexities of gene expression and protein diversity, the book illuminates how abnormal splicing contributes to aggressive tumor formation, affecting cellular functions such as proliferation, survival, and immune evasion. With a focus on understanding molecular mechanisms, this book unravels potential diagnostic and prognostic targets, opening doors for enhanced anti-cancer treatment efficacy. An indispensable resource for anyone intrigued by the interplay between gene splicing and cancer biology, it paves the way towards innovative therapeutic strategies.


Progress in Molecular and Subcellular Biology

Progress in Molecular and Subcellular Biology

Author: Philippe Jeanteur

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 195

ISBN-13: 3642751784

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Biological functions are almost exclusively attributed to macromolecules, i.e. nucleic acids, proteins and polysaccharides. To gain their complete functional activities these biomolecules have to associate with the nuclear matrix, the cytoskeleton and the cell/plasma membranes. It is the aim of this series to discuss actual aspects in the field of structure-associated genetic and epigenetic functional processes. This series of survey reviews fills the gap in structure-associated information flow, and is a vital reference work for scientists in molecular and cell biology.


Book Synopsis Progress in Molecular and Subcellular Biology by : Philippe Jeanteur

Download or read book Progress in Molecular and Subcellular Biology written by Philippe Jeanteur and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological functions are almost exclusively attributed to macromolecules, i.e. nucleic acids, proteins and polysaccharides. To gain their complete functional activities these biomolecules have to associate with the nuclear matrix, the cytoskeleton and the cell/plasma membranes. It is the aim of this series to discuss actual aspects in the field of structure-associated genetic and epigenetic functional processes. This series of survey reviews fills the gap in structure-associated information flow, and is a vital reference work for scientists in molecular and cell biology.


Progress in Nucleic Acid Research and Molecular Biology

Progress in Nucleic Acid Research and Molecular Biology

Author:

Publisher: Academic Press

Published: 1995-05-25

Total Pages: 345

ISBN-13: 9780080863382

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FROM THE REVIEWS OF THE PREVIOUS VOLUMES: "In perusing these chapters, I found much of interest. It is worth investigating." - P. Bricknell in BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY. "Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." -BRITISH MEDICAL JOURNAL. * * Provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology * Contributions from leaders in their fields * Abundant references


Book Synopsis Progress in Nucleic Acid Research and Molecular Biology by :

Download or read book Progress in Nucleic Acid Research and Molecular Biology written by and published by Academic Press. This book was released on 1995-05-25 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: FROM THE REVIEWS OF THE PREVIOUS VOLUMES: "In perusing these chapters, I found much of interest. It is worth investigating." - P. Bricknell in BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY. "Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." -BRITISH MEDICAL JOURNAL. * * Provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology * Contributions from leaders in their fields * Abundant references


Genetic Engineering

Genetic Engineering

Author: Jane K. Setlow

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 346

ISBN-13: 1461306418

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Sixteen contributions cover such topics as the polymerase chain reaction; regulation of alternative splicing; human retinoblastoma susceptibility gene; control of translation initiation in mammalian cells; the utility of streptomycetes as hosts for gene cloning; folding of eukaryotic proteins produc


Book Synopsis Genetic Engineering by : Jane K. Setlow

Download or read book Genetic Engineering written by Jane K. Setlow and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sixteen contributions cover such topics as the polymerase chain reaction; regulation of alternative splicing; human retinoblastoma susceptibility gene; control of translation initiation in mammalian cells; the utility of streptomycetes as hosts for gene cloning; folding of eukaryotic proteins produc