The Construction of Analogy-Based Research Programs

The Construction of Analogy-Based Research Programs

Author: Rebecca Mertens

Publisher: transcript Verlag

Published: 2019-04-30

Total Pages: 225

ISBN-13: 383944442X

DOWNLOAD EBOOK

When the German chemist Emil Fischer presented his lock-and-key hypothesis in 1899, his analogy to describe the molecular relationship between enzymes and substrates quickly gained vast influence and provided future generations of scientists with a tool to investigate the relation between chemical structure and biological specificity. Rebecca Mertens explains the appeal of the lock-and-key analogy by its role in model building and in the construction of long-term, cross-generational research programs. She argues that a crucial feature of these research programs, namely ascertaining the continuity of core ideas and concepts, is provided by a certain way of analogy-based modelling.


Book Synopsis The Construction of Analogy-Based Research Programs by : Rebecca Mertens

Download or read book The Construction of Analogy-Based Research Programs written by Rebecca Mertens and published by transcript Verlag. This book was released on 2019-04-30 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: When the German chemist Emil Fischer presented his lock-and-key hypothesis in 1899, his analogy to describe the molecular relationship between enzymes and substrates quickly gained vast influence and provided future generations of scientists with a tool to investigate the relation between chemical structure and biological specificity. Rebecca Mertens explains the appeal of the lock-and-key analogy by its role in model building and in the construction of long-term, cross-generational research programs. She argues that a crucial feature of these research programs, namely ascertaining the continuity of core ideas and concepts, is provided by a certain way of analogy-based modelling.


Natural Product Based Drug Discovery Against Human Parasites

Natural Product Based Drug Discovery Against Human Parasites

Author: Archana Singh

Publisher: Springer Nature

Published: 2024-01-01

Total Pages: 602

ISBN-13: 9811996059

DOWNLOAD EBOOK

This book comprehensively reviews current and novel treatment strategies against human parasites, including protozoans and helminths, using natural products. The initial chapters summarize the conventional treatment strategies and natural-product based therapeutics against these parasites. It discusses biochemical tools and techniques for the discovery of natural product based drugs against human parasites. The book also covers the ingenious and innovative mechanisms to achieve drug resistance by the protozoan parasites and strategies to overcome the resistance. It entails mechanistic insight into the modulation of host immune responses to delay or inhibit parasite clearance and explores host-pathogen interactions that mediate immunity against subsequent parasite challenge. In turn, the volume helps in understanding the immunobiology of the parasites and tools to identify candidate vaccine antigens and novel delivery systems against the protozoan parasites. Lastly, it explores the role of advanced methods, including nanotechnology, marine bioprospecting, and microorganisms-derived biochemicals against the protozoan parasites. This book is useful for students and researchers of pharmacology, parasitology, zoology and other allied fields.​


Book Synopsis Natural Product Based Drug Discovery Against Human Parasites by : Archana Singh

Download or read book Natural Product Based Drug Discovery Against Human Parasites written by Archana Singh and published by Springer Nature. This book was released on 2024-01-01 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively reviews current and novel treatment strategies against human parasites, including protozoans and helminths, using natural products. The initial chapters summarize the conventional treatment strategies and natural-product based therapeutics against these parasites. It discusses biochemical tools and techniques for the discovery of natural product based drugs against human parasites. The book also covers the ingenious and innovative mechanisms to achieve drug resistance by the protozoan parasites and strategies to overcome the resistance. It entails mechanistic insight into the modulation of host immune responses to delay or inhibit parasite clearance and explores host-pathogen interactions that mediate immunity against subsequent parasite challenge. In turn, the volume helps in understanding the immunobiology of the parasites and tools to identify candidate vaccine antigens and novel delivery systems against the protozoan parasites. Lastly, it explores the role of advanced methods, including nanotechnology, marine bioprospecting, and microorganisms-derived biochemicals against the protozoan parasites. This book is useful for students and researchers of pharmacology, parasitology, zoology and other allied fields.​


Split and Splice

Split and Splice

Author: Hans-Jörg Rheinberger

Publisher: University of Chicago Press

Published: 2023-04-21

Total Pages: 244

ISBN-13: 0226825329

DOWNLOAD EBOOK

"Esteemed historian and philosopher of science Hans-Jörg Rheinberger explores the incredible diversity of scientific experimentation in his new book, which extends his ground-breaking epistemological studies of the life sciences and the experimental practices that have made them so productive. Rheinberger explores the materiality of experiment, of its objects and instruments, the construction of models, and myriad ways of making things visible. The first part of the book is devoted to the circumstances and conditions that give the process of experimentation its structural cachet and make it a device from which novelty can emerge. Then, in the second part, Rheinberger focuses on the relations that experimental systems develop among each other, specifically their characteristic temporal, spatial, and narrative dimensions. The concepts that guide his investigation emerge through accessible examples, most of which are drawn from molecular biology, including from the author's own laboratory notebooks from his years researching ribosomes. This is a tour de force by one of today's most influential theorists of scientific practice"--


Book Synopsis Split and Splice by : Hans-Jörg Rheinberger

Download or read book Split and Splice written by Hans-Jörg Rheinberger and published by University of Chicago Press. This book was released on 2023-04-21 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Esteemed historian and philosopher of science Hans-Jörg Rheinberger explores the incredible diversity of scientific experimentation in his new book, which extends his ground-breaking epistemological studies of the life sciences and the experimental practices that have made them so productive. Rheinberger explores the materiality of experiment, of its objects and instruments, the construction of models, and myriad ways of making things visible. The first part of the book is devoted to the circumstances and conditions that give the process of experimentation its structural cachet and make it a device from which novelty can emerge. Then, in the second part, Rheinberger focuses on the relations that experimental systems develop among each other, specifically their characteristic temporal, spatial, and narrative dimensions. The concepts that guide his investigation emerge through accessible examples, most of which are drawn from molecular biology, including from the author's own laboratory notebooks from his years researching ribosomes. This is a tour de force by one of today's most influential theorists of scientific practice"--


Nanomedicine

Nanomedicine

Author: Jonathan Simon

Publisher: CRC Press

Published: 2023-04-25

Total Pages: 185

ISBN-13: 1000841901

DOWNLOAD EBOOK

The book is an introduction to nanomedicine informed by a philosophical reflection about the domain and recent developments. It is an overview of the field, sketching out the main areas of current investment and research. The authors present some case-studies illustrating the different areas of research (nanopharmacy, theranostics and patient monitoring) as well as reflecting on the risks that accompany it, such as unanticipated impacts on human health and environmental toxicity. This introduction to a fast-growing field in modern medical research is of great interest to researchers working in many disciplines as well as the general public. In addition to an overview of the work currently ongoing, the authors critically assess these projects from an ethical and philosophical perspective. Key Features Provides an overview of nanomedicine Employs a reflective and coherent critical evaluation of the benefits and risks of nanomedicine Written in an accessible manner intended for a wide audience Related Titles Hehenberger, M. Nanomedicine: Science, Business, and impact (ISBN 978-9-8146-1376-7). Beg, S., et al. Nanomedicine for the treatment of Disease: From Concept to Application (ISBN 978-1-7746-3443-1) Brenner, S. The Clinical Nanomedicine Handbook (ISBN 978-1-1380-7578-8)


Book Synopsis Nanomedicine by : Jonathan Simon

Download or read book Nanomedicine written by Jonathan Simon and published by CRC Press. This book was released on 2023-04-25 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is an introduction to nanomedicine informed by a philosophical reflection about the domain and recent developments. It is an overview of the field, sketching out the main areas of current investment and research. The authors present some case-studies illustrating the different areas of research (nanopharmacy, theranostics and patient monitoring) as well as reflecting on the risks that accompany it, such as unanticipated impacts on human health and environmental toxicity. This introduction to a fast-growing field in modern medical research is of great interest to researchers working in many disciplines as well as the general public. In addition to an overview of the work currently ongoing, the authors critically assess these projects from an ethical and philosophical perspective. Key Features Provides an overview of nanomedicine Employs a reflective and coherent critical evaluation of the benefits and risks of nanomedicine Written in an accessible manner intended for a wide audience Related Titles Hehenberger, M. Nanomedicine: Science, Business, and impact (ISBN 978-9-8146-1376-7). Beg, S., et al. Nanomedicine for the treatment of Disease: From Concept to Application (ISBN 978-1-7746-3443-1) Brenner, S. The Clinical Nanomedicine Handbook (ISBN 978-1-1380-7578-8)


Towards a Carbon Neutral Future

Towards a Carbon Neutral Future

Author: Konstantinos Papadikis

Publisher: Springer Nature

Published:

Total Pages: 817

ISBN-13: 981997965X

DOWNLOAD EBOOK


Book Synopsis Towards a Carbon Neutral Future by : Konstantinos Papadikis

Download or read book Towards a Carbon Neutral Future written by Konstantinos Papadikis and published by Springer Nature. This book was released on with total page 817 pages. Available in PDF, EPUB and Kindle. Book excerpt:


U.S. Government Research Reports

U.S. Government Research Reports

Author:

Publisher:

Published: 1962

Total Pages: 1166

ISBN-13:

DOWNLOAD EBOOK


Book Synopsis U.S. Government Research Reports by :

Download or read book U.S. Government Research Reports written by and published by . This book was released on 1962 with total page 1166 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Teaching Science with Analogies

Teaching Science with Analogies

Author:

Publisher:

Published: 1994

Total Pages: 32

ISBN-13:

DOWNLOAD EBOOK


Book Synopsis Teaching Science with Analogies by :

Download or read book Teaching Science with Analogies written by and published by . This book was released on 1994 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Put Reading First: the Research Building Blocks for Teaching Children to Read

Put Reading First: the Research Building Blocks for Teaching Children to Read

Author: Bonnie B. Armbruster

Publisher: DIANE Publishing

Published: 2010-11

Total Pages: 60

ISBN-13: 143793756X

DOWNLOAD EBOOK


Book Synopsis Put Reading First: the Research Building Blocks for Teaching Children to Read by : Bonnie B. Armbruster

Download or read book Put Reading First: the Research Building Blocks for Teaching Children to Read written by Bonnie B. Armbruster and published by DIANE Publishing. This book was released on 2010-11 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Analogy as Structure and Process

Analogy as Structure and Process

Author: Esa Itkonen

Publisher: John Benjamins Publishing

Published: 2005-01-01

Total Pages: 272

ISBN-13: 9789027223661

DOWNLOAD EBOOK

The concept of analogy is of central concern to modern cognitive scientists, whereas it has been largely neglected in linguistics in the past four decades. The goal of this thought-provoking book is (1) to introduce a cognitively and linguistically viable notion of analogy; and (2) to re-establish and build on traditional linguistic analogy-based research. As a starting point, a general definition of analogy is offered that makes the distinction between analogy-as-structure and analogy-as-process. Chapter 2 deals with analogy as used in traditional linguistics. It demonstrates how phonology, morphology, syntax, semantics, and diachronic linguistics make use of analogy and discusses linguistic domains in which analogy does or did not work. The appendix gives a description of a computer program, which performs such instances of analogy-based syntactic analysis as have long been claimed impossible. Chapter 3 supports the ultimate (non-modular) 'unity of the mind' and discusses the existence of pervasive analogies between language and such cognitive domains as vision, music, and logic. The final chapter presents evidence for the view that the cosmology of every culture is based on analogy. At a more abstract level, the role of analogy in scientific change is scrutinized, resulting in a meta-analogy between myth and science.


Book Synopsis Analogy as Structure and Process by : Esa Itkonen

Download or read book Analogy as Structure and Process written by Esa Itkonen and published by John Benjamins Publishing. This book was released on 2005-01-01 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of analogy is of central concern to modern cognitive scientists, whereas it has been largely neglected in linguistics in the past four decades. The goal of this thought-provoking book is (1) to introduce a cognitively and linguistically viable notion of analogy; and (2) to re-establish and build on traditional linguistic analogy-based research. As a starting point, a general definition of analogy is offered that makes the distinction between analogy-as-structure and analogy-as-process. Chapter 2 deals with analogy as used in traditional linguistics. It demonstrates how phonology, morphology, syntax, semantics, and diachronic linguistics make use of analogy and discusses linguistic domains in which analogy does or did not work. The appendix gives a description of a computer program, which performs such instances of analogy-based syntactic analysis as have long been claimed impossible. Chapter 3 supports the ultimate (non-modular) 'unity of the mind' and discusses the existence of pervasive analogies between language and such cognitive domains as vision, music, and logic. The final chapter presents evidence for the view that the cosmology of every culture is based on analogy. At a more abstract level, the role of analogy in scientific change is scrutinized, resulting in a meta-analogy between myth and science.


Current Thoughts on the Brain-Computer Analogy - All Metaphors Are Wrong, But Some Are Useful

Current Thoughts on the Brain-Computer Analogy - All Metaphors Are Wrong, But Some Are Useful

Author: Giorgio Matassi

Publisher: Frontiers Media SA

Published: 2023-03-22

Total Pages: 139

ISBN-13: 2832516513

DOWNLOAD EBOOK


Book Synopsis Current Thoughts on the Brain-Computer Analogy - All Metaphors Are Wrong, But Some Are Useful by : Giorgio Matassi

Download or read book Current Thoughts on the Brain-Computer Analogy - All Metaphors Are Wrong, But Some Are Useful written by Giorgio Matassi and published by Frontiers Media SA. This book was released on 2023-03-22 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: