The Glioma Book

The Glioma Book

Author: Michael E. Sughrue

Publisher: Thieme

Published: 2019-10-25

Total Pages: 827

ISBN-13: 1626234450

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A unique resource on glioma leverages advances and firsthand insights to enact meaningful change Glioblastoma (GBM) or glioma is an extremely aggressive and malignant brain tumor, with cell infiltration, rapid invasion, and a high frequency of relapse. The Glioma Book by neurosurgeon Michael Sughrue is a highly personal book — a culmination of two years of writing and more than 1,000 surgeries. It presents a unique viewpoint with the potential to transform the traditional paradigm that too often informs treatment of this universally fatal brain tumor. The book reinterprets the role of the cerebrum and sub-cortex, leverages scientific advances to improve cytoreduction and reduce neurological deficits, and challenges the myth of the "inoperable" glioma. This is the first step-by-step technical guide focused on aggressively resecting different types of gliomas. The book is logically organized, starting with a foundation of fundamental knowledge, then progressing to practical applications. Chapters focus on the skills necessary to perform glioma surgery, specific techniques, and systematic approaches to gliomas in different brain regions. Numerous case examples illuminate concepts introduced earlier in the book and explain how to perform these procedures About 30 high quality videos posted online provide insightful procedural guidance The role of connectomic imaging in visualizing the cerebrum, and other innovative techniques including awake brain mapping and diffusion tensor tractography Neurosurgeons who embrace the concepts in this book will realize they can change the glioma treatment paradigm. Continually improving techniques and viewing a glioma diagnosis as a battle for a patient's life, rather than an exercise in inevitable failure can impart progress in treating this devastating disease.


Book Synopsis The Glioma Book by : Michael E. Sughrue

Download or read book The Glioma Book written by Michael E. Sughrue and published by Thieme. This book was released on 2019-10-25 with total page 827 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique resource on glioma leverages advances and firsthand insights to enact meaningful change Glioblastoma (GBM) or glioma is an extremely aggressive and malignant brain tumor, with cell infiltration, rapid invasion, and a high frequency of relapse. The Glioma Book by neurosurgeon Michael Sughrue is a highly personal book — a culmination of two years of writing and more than 1,000 surgeries. It presents a unique viewpoint with the potential to transform the traditional paradigm that too often informs treatment of this universally fatal brain tumor. The book reinterprets the role of the cerebrum and sub-cortex, leverages scientific advances to improve cytoreduction and reduce neurological deficits, and challenges the myth of the "inoperable" glioma. This is the first step-by-step technical guide focused on aggressively resecting different types of gliomas. The book is logically organized, starting with a foundation of fundamental knowledge, then progressing to practical applications. Chapters focus on the skills necessary to perform glioma surgery, specific techniques, and systematic approaches to gliomas in different brain regions. Numerous case examples illuminate concepts introduced earlier in the book and explain how to perform these procedures About 30 high quality videos posted online provide insightful procedural guidance The role of connectomic imaging in visualizing the cerebrum, and other innovative techniques including awake brain mapping and diffusion tensor tractography Neurosurgeons who embrace the concepts in this book will realize they can change the glioma treatment paradigm. Continually improving techniques and viewing a glioma diagnosis as a battle for a patient's life, rather than an exercise in inevitable failure can impart progress in treating this devastating disease.

Glioblastoma:

Glioblastoma:

Author: Swapan K. Ray

Publisher: Springer Science & Business Media

Published: 2009-10-31

Total Pages: 427

ISBN-13: 1441904107

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Glioblastoma is the most malignant brain tumor that still remains incurable. It is such a deadly disease that patients do not survive more than a few months after diagnosis. Our understanding of the histopathology and molecular mechanisms of formation of glioblastoma is rapidly advancing so as to provide us clues for devising rational therapeutic strategies for treatment of this malignancy. It is important that we continue to improve our knowledge about the pathogenesis of this devastating disease and explore new areas to find successful therapeutic strategies. Various approaches such as sophisticated imaging techniques, improved surgical procedures, ground-breaking strategies for radiotherapy, chemotherapy, immunotherapy, chemoimmunotherapy, and photodynamic therapy are being used for eradicating glioblastoma. Hopefully, this book will be an important source of information on glioblastoma and therefore be highly useful to the students, postdoctoral fellows, principal investigators, and clinicians involved in this field.


Book Synopsis Glioblastoma: by : Swapan K. Ray

Download or read book Glioblastoma: written by Swapan K. Ray and published by Springer Science & Business Media. This book was released on 2009-10-31 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glioblastoma is the most malignant brain tumor that still remains incurable. It is such a deadly disease that patients do not survive more than a few months after diagnosis. Our understanding of the histopathology and molecular mechanisms of formation of glioblastoma is rapidly advancing so as to provide us clues for devising rational therapeutic strategies for treatment of this malignancy. It is important that we continue to improve our knowledge about the pathogenesis of this devastating disease and explore new areas to find successful therapeutic strategies. Various approaches such as sophisticated imaging techniques, improved surgical procedures, ground-breaking strategies for radiotherapy, chemotherapy, immunotherapy, chemoimmunotherapy, and photodynamic therapy are being used for eradicating glioblastoma. Hopefully, this book will be an important source of information on glioblastoma and therefore be highly useful to the students, postdoctoral fellows, principal investigators, and clinicians involved in this field.

Glioma Imaging

Glioma Imaging

Author: Whitney B. Pope

Publisher: Springer Nature

Published: 2019-11-11

Total Pages: 286

ISBN-13: 3030273598

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This book covers physiologic, metabolic and molecular imaging for gliomas. Gliomas are the most common primary brain tumors. Imaging is critical for glioma management because of its ability to noninvasively define the anatomic location and extent of disease. While conventional MRI is used to guide current treatments, multiple studies suggest molecular features of gliomas may be identified with noninvasive imaging, including physiologic MRI and amino acid positron emission tomography (PET). These advanced imaging techniques have the promise to help elucidate underlying tumor biology and provide important information that could be integrated into routine clinical practice. The text outlines current clinical practice including common scenarios in which imaging interpretation impacts patient management. Gaps in knowledge and potential areas of advancement based on the application of more experimental imaging techniques will be discussed. In reviewing this book, readers will learn: current standard imaging methodologies used in clinical practice for patients undergoing treatment for glioma and the implications of emerging treatment modalities including immunotherapy the theoretical basis for advanced imaging techniques including diffusion and perfusion MRI, MR spectroscopy, CEST and amino acid PET the relationship between imaging and molecular/genomic glioma features incorporated in the WHO 2016 classification update and the potential application of machine learning about the recently adopted and FDA approved standard brain tumor protocol for multicenter drug trials of the gaps in knowledge that impede optimal patient management and the cutting edge imaging techniques that could address these deficits


Book Synopsis Glioma Imaging by : Whitney B. Pope

Download or read book Glioma Imaging written by Whitney B. Pope and published by Springer Nature. This book was released on 2019-11-11 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers physiologic, metabolic and molecular imaging for gliomas. Gliomas are the most common primary brain tumors. Imaging is critical for glioma management because of its ability to noninvasively define the anatomic location and extent of disease. While conventional MRI is used to guide current treatments, multiple studies suggest molecular features of gliomas may be identified with noninvasive imaging, including physiologic MRI and amino acid positron emission tomography (PET). These advanced imaging techniques have the promise to help elucidate underlying tumor biology and provide important information that could be integrated into routine clinical practice. The text outlines current clinical practice including common scenarios in which imaging interpretation impacts patient management. Gaps in knowledge and potential areas of advancement based on the application of more experimental imaging techniques will be discussed. In reviewing this book, readers will learn: current standard imaging methodologies used in clinical practice for patients undergoing treatment for glioma and the implications of emerging treatment modalities including immunotherapy the theoretical basis for advanced imaging techniques including diffusion and perfusion MRI, MR spectroscopy, CEST and amino acid PET the relationship between imaging and molecular/genomic glioma features incorporated in the WHO 2016 classification update and the potential application of machine learning about the recently adopted and FDA approved standard brain tumor protocol for multicenter drug trials of the gaps in knowledge that impede optimal patient management and the cutting edge imaging techniques that could address these deficits

Navigating Life with a Brain Tumor

Navigating Life with a Brain Tumor

Author: Lynne P. Taylor

Publisher: Oxford University Press

Published: 2012-12-06

Total Pages: 230

ISBN-13: 0199897794

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Navigating Life with a Brain Tumor is a guide for anyone affected by brain tumors and their associated conditions-patients, family members, friends, and caregivers. Providing readily accessible information and real-world encouragement to people living with primary and metastatic brain tumors and their caregivers, this book discusses the basics of brain tumors, types of tumors, management of different tumors, related symptoms, treatments and side effects, the role of medical team members, and coping strategies from initial diagnosis throughout the course of the illness. At the same time, it also offers practical suggestions on symptom management and lifestyle modification, as well as real-life anecdotes and advice from both patients and family members and friends who are experiencing this diagnosis.


Book Synopsis Navigating Life with a Brain Tumor by : Lynne P. Taylor

Download or read book Navigating Life with a Brain Tumor written by Lynne P. Taylor and published by Oxford University Press. This book was released on 2012-12-06 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Navigating Life with a Brain Tumor is a guide for anyone affected by brain tumors and their associated conditions-patients, family members, friends, and caregivers. Providing readily accessible information and real-world encouragement to people living with primary and metastatic brain tumors and their caregivers, this book discusses the basics of brain tumors, types of tumors, management of different tumors, related symptoms, treatments and side effects, the role of medical team members, and coping strategies from initial diagnosis throughout the course of the illness. At the same time, it also offers practical suggestions on symptom management and lifestyle modification, as well as real-life anecdotes and advice from both patients and family members and friends who are experiencing this diagnosis.

A Statistic of One

A Statistic of One

Author: Stephen Hatrak

Publisher: iUniverse

Published: 2012-05-11

Total Pages: 92

ISBN-13: 9781475916355

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A Statistic of One: My Walk with Glioblastoma Multiforme traces Stephen Hatraks life from his diagnosis of glioblastoma multiforme, the deadliest of malignant brain tumors, to the present. He chronicles the trials and tribulations he faced and the losses he suffered along his journey. Faith and inner strength are formidable allies in overcoming any tragedy in ones life, and they played vital roles in his struggle. He was told from the start that the he might have twelve months to live; even so, he defi ed the odds and, six years later, is telling his own story. Despite the dire statistics associated with a diagnosis of glioblastoma, there are several stories of long-term survival; these stories gave him hope that this cancer could be tamed. To overcome this challenge in his life, he had to believe in himself and fi nd his inner sixth sense to strengthen his resolve. Along the way, he learned that life with brain cancer could be tough, but that he could be even tougher. What cancer cannot do.separate me from my soul, squash my spirit, and stop the sun from rising in the east and setting in the west; creating new tomorrows and new opportunities. A Statistic of One is an uplifting story of faith and perseverance; how we cope with challenge will determine how we move forward and live life to its fullest.


Book Synopsis A Statistic of One by : Stephen Hatrak

Download or read book A Statistic of One written by Stephen Hatrak and published by iUniverse. This book was released on 2012-05-11 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Statistic of One: My Walk with Glioblastoma Multiforme traces Stephen Hatraks life from his diagnosis of glioblastoma multiforme, the deadliest of malignant brain tumors, to the present. He chronicles the trials and tribulations he faced and the losses he suffered along his journey. Faith and inner strength are formidable allies in overcoming any tragedy in ones life, and they played vital roles in his struggle. He was told from the start that the he might have twelve months to live; even so, he defi ed the odds and, six years later, is telling his own story. Despite the dire statistics associated with a diagnosis of glioblastoma, there are several stories of long-term survival; these stories gave him hope that this cancer could be tamed. To overcome this challenge in his life, he had to believe in himself and fi nd his inner sixth sense to strengthen his resolve. Along the way, he learned that life with brain cancer could be tough, but that he could be even tougher. What cancer cannot do.separate me from my soul, squash my spirit, and stop the sun from rising in the east and setting in the west; creating new tomorrows and new opportunities. A Statistic of One is an uplifting story of faith and perseverance; how we cope with challenge will determine how we move forward and live life to its fullest.

High-Grade Gliomas

High-Grade Gliomas

Author: Gene H. Barnett

Publisher: Springer Science & Business Media

Published: 2007-11-21

Total Pages: 493

ISBN-13: 1597451851

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This is truly an exciting time in the field of neuro-oncology, particularly in the area of hi- grade gliomas. The management of patients with high-grade gliomas has historically been one of the most challenging and disheartening fields in medicine, where failure is the rule and longevity is the exception. The jaded often state that despite purported advances in surgical and radiotherapeutic techniques and a myriad of clinical trials of medical therapies, the s- vival statistics for glioblastoma have not changed in the last three decades. The nihilism associated with these tumors is such that some practitioners still advise against treatment or even biopsy, recommending palliative care with the diagnosis based only on history and an MRI scan. If the current state-of-the-art in the diagnosis and management of high-grade gliomas was truly so bleak, there would be no reason to compile and publish a monograph on the subject. The fact is that we have recently entered an era where real progress is being made in our understanding and treatment of high-grade gliomas that is directly benefiting some patients. We are slowly but surely chipping away at this problem. One approach has exploited correlations between particular molecular markers and therapeutic response. The first such “breakthrough” in high-grade glioma was the observation that loss of chromosomes 1p and 19q uniformly predict chemosensitivity in anaplastic oligodendrogliomas (1).


Book Synopsis High-Grade Gliomas by : Gene H. Barnett

Download or read book High-Grade Gliomas written by Gene H. Barnett and published by Springer Science & Business Media. This book was released on 2007-11-21 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is truly an exciting time in the field of neuro-oncology, particularly in the area of hi- grade gliomas. The management of patients with high-grade gliomas has historically been one of the most challenging and disheartening fields in medicine, where failure is the rule and longevity is the exception. The jaded often state that despite purported advances in surgical and radiotherapeutic techniques and a myriad of clinical trials of medical therapies, the s- vival statistics for glioblastoma have not changed in the last three decades. The nihilism associated with these tumors is such that some practitioners still advise against treatment or even biopsy, recommending palliative care with the diagnosis based only on history and an MRI scan. If the current state-of-the-art in the diagnosis and management of high-grade gliomas was truly so bleak, there would be no reason to compile and publish a monograph on the subject. The fact is that we have recently entered an era where real progress is being made in our understanding and treatment of high-grade gliomas that is directly benefiting some patients. We are slowly but surely chipping away at this problem. One approach has exploited correlations between particular molecular markers and therapeutic response. The first such “breakthrough” in high-grade glioma was the observation that loss of chromosomes 1p and 19q uniformly predict chemosensitivity in anaplastic oligodendrogliomas (1).

New Techniques for Management of ‘Inoperable’ Gliomas

New Techniques for Management of ‘Inoperable’ Gliomas

Author: Michael E. Sughrue

Publisher: Academic Press

Published: 2019-08-03

Total Pages: 256

ISBN-13: 0128136340

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New Techniques for Management of 'Inoperable' Gliomas radically challenges the assumption that certain gliomas cannot be removed with modern techniques, contesting stereotypical thinking and establishing new paradigms in the field. Gliomas are primary brain tumors which are often fatal. Recent data has demonstrated that despite the fact that surgery cannot cure gliomas, patient survival is substantially improved by removing as much of the tumor as possible. This fact has raised the imperative that neurologists try to improve techniques to bring surgical resection to as many patients as possible. This book brings new insights and technologies to the forefront, giving hope to patients. Provides the first comprehensive book to discuss techniques for removing gliomas that are traditionally deemed ‘inoperable’ Presents a great reference tool that challenges stereotypical thinking by offering techniques by innovative surgeons Includes chapters that are organized by different glioma types and surgery/techniques


Book Synopsis New Techniques for Management of ‘Inoperable’ Gliomas by : Michael E. Sughrue

Download or read book New Techniques for Management of ‘Inoperable’ Gliomas written by Michael E. Sughrue and published by Academic Press. This book was released on 2019-08-03 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Techniques for Management of 'Inoperable' Gliomas radically challenges the assumption that certain gliomas cannot be removed with modern techniques, contesting stereotypical thinking and establishing new paradigms in the field. Gliomas are primary brain tumors which are often fatal. Recent data has demonstrated that despite the fact that surgery cannot cure gliomas, patient survival is substantially improved by removing as much of the tumor as possible. This fact has raised the imperative that neurologists try to improve techniques to bring surgical resection to as many patients as possible. This book brings new insights and technologies to the forefront, giving hope to patients. Provides the first comprehensive book to discuss techniques for removing gliomas that are traditionally deemed ‘inoperable’ Presents a great reference tool that challenges stereotypical thinking by offering techniques by innovative surgeons Includes chapters that are organized by different glioma types and surgery/techniques

Diffuse Low-Grade Gliomas in Adults

Diffuse Low-Grade Gliomas in Adults

Author: Hugues Duffau

Publisher: Springer Science & Business Media

Published: 2013-03-19

Total Pages: 498

ISBN-13: 1447122135

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This book presents the latest research pertaining to the diagnosis, therapy and management of diffuse low-grade gliomas (DLGG) in adults, with a particular focus on the path towards individualised therapy for this kind of tumour. Recent research on the natural history of DLGGs and their interaction with the brain has led to new diagnostic and therapeutic strategies which increase survival and quality of life of the patient, and these methods are described in this book.


Book Synopsis Diffuse Low-Grade Gliomas in Adults by : Hugues Duffau

Download or read book Diffuse Low-Grade Gliomas in Adults written by Hugues Duffau and published by Springer Science & Business Media. This book was released on 2013-03-19 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest research pertaining to the diagnosis, therapy and management of diffuse low-grade gliomas (DLGG) in adults, with a particular focus on the path towards individualised therapy for this kind of tumour. Recent research on the natural history of DLGGs and their interaction with the brain has led to new diagnostic and therapeutic strategies which increase survival and quality of life of the patient, and these methods are described in this book.

Navigating Glioblastoma

Navigating Glioblastoma

Author: Sally Connolly

Publisher: McFarland

Published: 2020-07-10

Total Pages: 211

ISBN-13: 1476641064

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A stale marriage. A deadly diagnosis. For Sally Connolly, three years of struggle followed her husband Peter's surgery for terminal brain cancer at age 61. Choosing treatment options that interfered least with his career, Peter focused his limited energy on work, with little left for his family, further straining the marriage during his remaining days. Connolly's clear-eyed and affecting memoir recounts their wrangling over gender roles, money management, domestic decisions and lifestyle changes. Through their traumatic journey, they find humor and comfort in unexpected places.


Book Synopsis Navigating Glioblastoma by : Sally Connolly

Download or read book Navigating Glioblastoma written by Sally Connolly and published by McFarland. This book was released on 2020-07-10 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: A stale marriage. A deadly diagnosis. For Sally Connolly, three years of struggle followed her husband Peter's surgery for terminal brain cancer at age 61. Choosing treatment options that interfered least with his career, Peter focused his limited energy on work, with little left for his family, further straining the marriage during his remaining days. Connolly's clear-eyed and affecting memoir recounts their wrangling over gender roles, money management, domestic decisions and lifestyle changes. Through their traumatic journey, they find humor and comfort in unexpected places.

Novel Treatment Strategies for Glioblastoma

Novel Treatment Strategies for Glioblastoma

Author: Stanley Stylli

Publisher: Mdpi AG

Published: 2021-12-21

Total Pages: 282

ISBN-13: 9783036525990

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This book is a compilation of articles that brings together current knowledge from an international team of contributors who are dedicated investigators exploring novel strategies for the treatment of glioblastoma. These articles describe some of the latest concepts that will provide students, researchers and clinicians with an overview of the therapeutic approaches being developed in the field of neuro-oncology to combat this deadly disease.


Book Synopsis Novel Treatment Strategies for Glioblastoma by : Stanley Stylli

Download or read book Novel Treatment Strategies for Glioblastoma written by Stanley Stylli and published by Mdpi AG. This book was released on 2021-12-21 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compilation of articles that brings together current knowledge from an international team of contributors who are dedicated investigators exploring novel strategies for the treatment of glioblastoma. These articles describe some of the latest concepts that will provide students, researchers and clinicians with an overview of the therapeutic approaches being developed in the field of neuro-oncology to combat this deadly disease.