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Molecular Basis for the Aging of Human Skin

Author: Taihao Quan

Publisher:

Published: 2017

Total Pages: 0

ISBN-13: 9781536124682

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Skin is the most voluminous connective tissue of the body. Skin, like all other human organs, undergoes progressive alterations as a consequence of the passage of time (natural aging). However, human skin, unlike other organs, continuously experiences harmful exposure from environmental sources such as solar ultraviolet irradiation (photoaging). As the bulk of the skin is largely comprised of connective tissue collagen, the primary molecular features of aged human skin are reduced production of collagen and accumulation of damaged collagen. Age-related alterations of dermal connective collagen cause an aberrant tissue microenvironment, which deleteriously influence the risk of developing age-related skin diseases. This book comprehensively describes the molecular mechanisms of human skin connective tissue aging by emphasizing age-related dermal microenvironment as a strategy for improving our quality of life as well as for preventive and therapeutic intervention of age-related skin diseases. This book is an essential resource for the development of mechanisms-based anti-skin aging products.

Book Synopsis Molecular Basis for the Aging of Human Skin by : Taihao Quan

Download or read book Molecular Basis for the Aging of Human Skin written by Taihao Quan and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Skin is the most voluminous connective tissue of the body. Skin, like all other human organs, undergoes progressive alterations as a consequence of the passage of time (natural aging). However, human skin, unlike other organs, continuously experiences harmful exposure from environmental sources such as solar ultraviolet irradiation (photoaging). As the bulk of the skin is largely comprised of connective tissue collagen, the primary molecular features of aged human skin are reduced production of collagen and accumulation of damaged collagen. Age-related alterations of dermal connective collagen cause an aberrant tissue microenvironment, which deleteriously influence the risk of developing age-related skin diseases. This book comprehensively describes the molecular mechanisms of human skin connective tissue aging by emphasizing age-related dermal microenvironment as a strategy for improving our quality of life as well as for preventive and therapeutic intervention of age-related skin diseases. This book is an essential resource for the development of mechanisms-based anti-skin aging products.

The Molecular Basis for the Aging of Human Skin

Author: Taihao Quan

Publisher:

Published: 2017

Total Pages: 240

ISBN-13: 9781536124699

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Book Synopsis The Molecular Basis for the Aging of Human Skin by : Taihao Quan

Download or read book The Molecular Basis for the Aging of Human Skin written by Taihao Quan and published by . This book was released on 2017 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Skin is the most voluminous connective tissue of the body. Skin, like all other human organs, undergoes progressive alterations as a consequence of the passage of time (natural aging). However, human skin, unlike other organs, continuously experiences harmful exposure from environmental sources such as solar ultraviolet irradiation (photoaging). As the bulk of the skin is largely comprised of connective tissue collagen, the primary molecular features of aged human skin are reduced production of collagen and accumulation of damaged collagen. Age-related alterations of dermal connective collagen cause an aberrant tissue microenvironment, which deleteriously influence the risk of developing age-related skin diseases. This book comprehensively describes the molecular mechanisms of human skin connective tissue aging by emphasizing age-related dermal microenvironment as a strategy for improving our quality of life as well as for preventive and therapeutic intervention of age-related skin diseases. This book is an essential resource for the development of mechanisms-based anti-skin aging products.

Molecular Mechanisms of Skin Aging and Age-Related Diseases

Author: Taihao Quan

Publisher: CRC Press

Published: 2016-04-21

Total Pages: 263

ISBN-13: 1498704654

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Our skin changes as we age. It becomes thinner and loses fat, making it less plump and smooth. Clinically, aged skin is characterized by wrinkles, sagging, age spots and dryness. Emphasizing laboratory and clinical research, this book comprehensively describes the molecular mechanisms of human skin-aging and age-related skin diseases. This includes molecular understanding of the development of aging skin and its prevention as well as mechanisms-based clinical rejuvenation. The book also focuses on research to develop mechanisms-based anti-skin-aging products.

Book Synopsis Molecular Mechanisms of Skin Aging and Age-Related Diseases by : Taihao Quan

Download or read book Molecular Mechanisms of Skin Aging and Age-Related Diseases written by Taihao Quan and published by CRC Press. This book was released on 2016-04-21 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our skin changes as we age. It becomes thinner and loses fat, making it less plump and smooth. Clinically, aged skin is characterized by wrinkles, sagging, age spots and dryness. Emphasizing laboratory and clinical research, this book comprehensively describes the molecular mechanisms of human skin-aging and age-related skin diseases. This includes molecular understanding of the development of aging skin and its prevention as well as mechanisms-based clinical rejuvenation. The book also focuses on research to develop mechanisms-based anti-skin-aging products.

Molecular Basis of Aging

Author: A Roy

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 411

ISBN-13: 0323151558

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Molecular Basis of Aging is a collection of papers that discuss the molecular aspects of aging in the light of molecular biology, biochemical gerontology, and genetics. Each chapter of the book contains a different study about the topic, which includes the effects of aging on DNA synthesis; the amplification of extrachromosomal circular copies and mitochondrial DNA during aging; and the altered actions of hormones and neurotransmitters during aging. The book also encompasses the loss of responsiveness to growth factors in cell senescence; the integration of cellular-molecular and neuroendocrine concepts of aging; changes and inactivation of enzymes during aging; and the relationship of aging with free radicals. The text is recommended for molecular biologists, biochemists, and gerontologists who wish to study further the effects of aging on the body on a molecular level.

Book Synopsis Molecular Basis of Aging by : A Roy

Download or read book Molecular Basis of Aging written by A Roy and published by Elsevier. This book was released on 2012-12-02 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Basis of Aging is a collection of papers that discuss the molecular aspects of aging in the light of molecular biology, biochemical gerontology, and genetics. Each chapter of the book contains a different study about the topic, which includes the effects of aging on DNA synthesis; the amplification of extrachromosomal circular copies and mitochondrial DNA during aging; and the altered actions of hormones and neurotransmitters during aging. The book also encompasses the loss of responsiveness to growth factors in cell senescence; the integration of cellular-molecular and neuroendocrine concepts of aging; changes and inactivation of enzymes during aging; and the relationship of aging with free radicals. The text is recommended for molecular biologists, biochemists, and gerontologists who wish to study further the effects of aging on the body on a molecular level.

Molecular Basis of Aging

Author: Alvaro Macieira-Coelho

Publisher: CRC Press

Published: 2017-11-22

Total Pages: 666

ISBN-13: 1351359967

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Using a new, integrative approach, Molecular Basis of Aging describes the aging phenomenon within mammalian organisms from the perspective of changes in information storage and coordination between hierarchical orders of structure. This unique approach provides the reader with a thorough insight into the evolution of molecular, cellular, tissue, and organ systems and processes in mammals. This informative volume contains up-to-date reviews of:

Book Synopsis Molecular Basis of Aging by : Alvaro Macieira-Coelho

Download or read book Molecular Basis of Aging written by Alvaro Macieira-Coelho and published by CRC Press. This book was released on 2017-11-22 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using a new, integrative approach, Molecular Basis of Aging describes the aging phenomenon within mammalian organisms from the perspective of changes in information storage and coordination between hierarchical orders of structure. This unique approach provides the reader with a thorough insight into the evolution of molecular, cellular, tissue, and organ systems and processes in mammals. This informative volume contains up-to-date reviews of:

Molecular Basis and Emerging Strategies for Anti-aging Interventions

Author: Syed Ibrahim Rizvi

Publisher: Springer

Published: 2018-11-02

Total Pages: 386

ISBN-13: 9811316996

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This book describes the nature of aging, age-related disorders, and the molecular principles of emerging strategies for anti-aging interventions, while also discussing the discovery of targets for geroprotective drugs. Although significant medical advances in the treatment and eradication of life-threatening conditions such as cardiovascular and infectious disease have been made over the past five decades, the prevalence of age-related disorders still remains high in older populations. Intervening into aging is the next frontier in contemporary medicine, and will be of increasing importance over time, as other sources of poor health are combated more and more successfully. Given the universal interest in anti-aging strategies, the book will appeal to a very broad audience. It addresses a diverse range of anti-aging interventions – including stem cells, autophagy, senolytics, anti-inflammatory methods, and telomerase induction – that will be of interest to scientists and researchers from various disciplines in the life sciences.

Book Synopsis Molecular Basis and Emerging Strategies for Anti-aging Interventions by : Syed Ibrahim Rizvi

Download or read book Molecular Basis and Emerging Strategies for Anti-aging Interventions written by Syed Ibrahim Rizvi and published by Springer. This book was released on 2018-11-02 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the nature of aging, age-related disorders, and the molecular principles of emerging strategies for anti-aging interventions, while also discussing the discovery of targets for geroprotective drugs. Although significant medical advances in the treatment and eradication of life-threatening conditions such as cardiovascular and infectious disease have been made over the past five decades, the prevalence of age-related disorders still remains high in older populations. Intervening into aging is the next frontier in contemporary medicine, and will be of increasing importance over time, as other sources of poor health are combated more and more successfully. Given the universal interest in anti-aging strategies, the book will appeal to a very broad audience. It addresses a diverse range of anti-aging interventions – including stem cells, autophagy, senolytics, anti-inflammatory methods, and telomerase induction – that will be of interest to scientists and researchers from various disciplines in the life sciences.

Molecular Mechanisms of the Aging Process and Rejuvenation

Author: Naofumi Shiomi

Publisher: BoD – Books on Demand

Published: 2016-08-31

Total Pages: 128

ISBN-13: 9535125680

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Numerous studies had been performed to elucidate the mechanisms of aging and to achieve rejuvenation, with some success reported in recent years. However, at present, the findings from those studies are not sufficient to resolve the issue of aging. This book presents an overview of recent topics on cellular aging and rejuvenation. In the early chapters, the molecular mechanisms of aging via the activities of clock and ion channel proteins, in addition to overall aspects, are discussed. In the latter part, the aging of the skin, immune system, and brain is discussed. This book will prove useful for those studying or developing new drugs to counter the aging process and will encourage the development of novel ideas for rejuvenation.

Book Synopsis Molecular Mechanisms of the Aging Process and Rejuvenation by : Naofumi Shiomi

Download or read book Molecular Mechanisms of the Aging Process and Rejuvenation written by Naofumi Shiomi and published by BoD – Books on Demand. This book was released on 2016-08-31 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerous studies had been performed to elucidate the mechanisms of aging and to achieve rejuvenation, with some success reported in recent years. However, at present, the findings from those studies are not sufficient to resolve the issue of aging. This book presents an overview of recent topics on cellular aging and rejuvenation. In the early chapters, the molecular mechanisms of aging via the activities of clock and ion channel proteins, in addition to overall aspects, are discussed. In the latter part, the aging of the skin, immune system, and brain is discussed. This book will prove useful for those studying or developing new drugs to counter the aging process and will encourage the development of novel ideas for rejuvenation.

Skin Aging

Author: Barbara A. Gilchrest

Publisher: Springer Science & Business Media

Published: 2006-04-20

Total Pages: 205

ISBN-13: 3540329536

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The topic of skin aging is of growing importance to all working in the field of dermatology, aesthetic medicine and cosmetic medicine. Two internationally well-known and leading experts in the field present a comprehensive state-of-the-art review on all aspects of skin aging. With its clear, concise and reader-friendly format this book has all the potential to become the Bible of skin aging. Every specialist interested in dermatology, aesthetic medicine, cosmetic science, cutaneous biology and aging research will find indispensable information of great value for his or her daily work.

Book Synopsis Skin Aging by : Barbara A. Gilchrest

Download or read book Skin Aging written by Barbara A. Gilchrest and published by Springer Science & Business Media. This book was released on 2006-04-20 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: The topic of skin aging is of growing importance to all working in the field of dermatology, aesthetic medicine and cosmetic medicine. Two internationally well-known and leading experts in the field present a comprehensive state-of-the-art review on all aspects of skin aging. With its clear, concise and reader-friendly format this book has all the potential to become the Bible of skin aging. Every specialist interested in dermatology, aesthetic medicine, cosmetic science, cutaneous biology and aging research will find indispensable information of great value for his or her daily work.

Epigenetics of Aging

Author: Trygve O. Tollefsbol

Publisher: Springer Science & Business Media

Published: 2009-11-11

Total Pages: 462

ISBN-13: 1441906398

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Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.

Book Synopsis Epigenetics of Aging by : Trygve O. Tollefsbol

Download or read book Epigenetics of Aging written by Trygve O. Tollefsbol and published by Springer Science & Business Media. This book was released on 2009-11-11 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.

Textbook of Aging Skin

Author: Miranda A. Farage

Publisher: Springer Science & Business Media

Published: 2009-12-02

Total Pages: 1255

ISBN-13: 3540896554

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This comprehensive ‘Major Reference Book’ compiles all current and latest information on aging skin in a two-volume set. Highly structured with a reader-friendly format, it covers a wide range of areas such as basic sciences, the different diseases and conditions which occur with aging (from malignant to non-malignant), the latest techniques and methods being used such as bioengineering methods and biometrics as well as toxicological and safety considerations for the elderly population. It also illustrates the global consumers’ sociological and psychological implications, ethnicity and gender differences and includes marketing considerations for this elderly group. This unique and comprehensive guide will become the main reference textbook on this topic.

Book Synopsis Textbook of Aging Skin by : Miranda A. Farage

Download or read book Textbook of Aging Skin written by Miranda A. Farage and published by Springer Science & Business Media. This book was released on 2009-12-02 with total page 1255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive ‘Major Reference Book’ compiles all current and latest information on aging skin in a two-volume set. Highly structured with a reader-friendly format, it covers a wide range of areas such as basic sciences, the different diseases and conditions which occur with aging (from malignant to non-malignant), the latest techniques and methods being used such as bioengineering methods and biometrics as well as toxicological and safety considerations for the elderly population. It also illustrates the global consumers’ sociological and psychological implications, ethnicity and gender differences and includes marketing considerations for this elderly group. This unique and comprehensive guide will become the main reference textbook on this topic.