The Neuropharmacology of Nicotine Dependence

The Neuropharmacology of Nicotine Dependence

Author: David J.K. Balfour

Publisher: Springer

Published: 2015-01-31

Total Pages: 172

ISBN-13: 3319134825

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The primary purpose of this book and its companion volume The Behavioral Genetics of Nicotine and Tobacco is to explore the ways in which recent studies on nicotine and its role in tobacco addiction have opened our eyes to the psychopharmacological properties of this unique and fascinating drug. While The Behavioral Genetics of Nicotine and Tobacco considers the molecular and genetic factors which influence behavioral responses to nicotine and how these may impact on the role of nicotine in tobacco dependence, the present book focuses on the complex neural and psychological mechanisms that mediate nicotine dependence in experimental animal models and their relationship to tobacco addiction in humans. These volumes will provide readers a contemporary overview of current research on nicotine psychopharmacology and its role in tobacco dependence from leaders in this field of researchand will hopefully prove valuable to those who are developing their own research programmes in this important topic.


Book Synopsis The Neuropharmacology of Nicotine Dependence by : David J.K. Balfour

Download or read book The Neuropharmacology of Nicotine Dependence written by David J.K. Balfour and published by Springer. This book was released on 2015-01-31 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: The primary purpose of this book and its companion volume The Behavioral Genetics of Nicotine and Tobacco is to explore the ways in which recent studies on nicotine and its role in tobacco addiction have opened our eyes to the psychopharmacological properties of this unique and fascinating drug. While The Behavioral Genetics of Nicotine and Tobacco considers the molecular and genetic factors which influence behavioral responses to nicotine and how these may impact on the role of nicotine in tobacco dependence, the present book focuses on the complex neural and psychological mechanisms that mediate nicotine dependence in experimental animal models and their relationship to tobacco addiction in humans. These volumes will provide readers a contemporary overview of current research on nicotine psychopharmacology and its role in tobacco dependence from leaders in this field of researchand will hopefully prove valuable to those who are developing their own research programmes in this important topic.

The Neurobiology and Genetics of Nicotine and Tobacco

The Neurobiology and Genetics of Nicotine and Tobacco

Author: David J.K. Balfour

Publisher: Springer

Published: 2015-02-05

Total Pages: 233

ISBN-13: 3319136658

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The primary purpose of this book and its companion volume The Neuropharmacology of Nicotine Dependence is to explore the ways in which recent studies on nicotine and its role in tobacco addiction have opened our eyes to the psychopharmacological properties of this unique and fascinating drug. While the present volume considers the molecular and genetic factors which influence behavioral responses to nicotine and how these may impact on the role of nicotine in tobacco dependence, the book The Neuropharmacology of Nicotine Dependence focuses on the complex neural and psychological mechanisms that mediate nicotine dependence in experimental animal models and their relationship to tobacco addiction in humans. These volumes will provide readers with a contemporary overview of current research on nicotine psychopharmacology and its role in tobacco dependence from leaders in this field of research and will hopefully prove valuable to those who are developing their own research programmes in this important topic.


Book Synopsis The Neurobiology and Genetics of Nicotine and Tobacco by : David J.K. Balfour

Download or read book The Neurobiology and Genetics of Nicotine and Tobacco written by David J.K. Balfour and published by Springer. This book was released on 2015-02-05 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: The primary purpose of this book and its companion volume The Neuropharmacology of Nicotine Dependence is to explore the ways in which recent studies on nicotine and its role in tobacco addiction have opened our eyes to the psychopharmacological properties of this unique and fascinating drug. While the present volume considers the molecular and genetic factors which influence behavioral responses to nicotine and how these may impact on the role of nicotine in tobacco dependence, the book The Neuropharmacology of Nicotine Dependence focuses on the complex neural and psychological mechanisms that mediate nicotine dependence in experimental animal models and their relationship to tobacco addiction in humans. These volumes will provide readers with a contemporary overview of current research on nicotine psychopharmacology and its role in tobacco dependence from leaders in this field of research and will hopefully prove valuable to those who are developing their own research programmes in this important topic.

Neuroscience of Nicotine

Neuroscience of Nicotine

Author: Victor R. Preedy

Publisher: Academic Press

Published: 2019-03-20

Total Pages: 566

ISBN-13: 0128130369

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Neuroscience of Nicotine: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of nicotine addiction and its effects on the brain. Offering thorough coverage of all aspects of nicotine research, treatment, policy and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of nicotine misuse. With an estimated one billion individuals worldwide classified as tobacco users—and tobacco use often being synonymous with nicotine addiction—nicotine is one of the world’s most common addictive substances, and a frequent comorbidity of misuse of other common addictive substances. Nicotine alters a variety of neurological processes, from molecular biology, to cognition, and quitting is exceedingly difficult because of the number of withdrawal symptoms that accompany the process. Integrates cutting-edge research on the pharmacological, cellular and molecular aspects of nicotine use, along with its effects on neurobiological function Discusses nicotine use as a component of dual-use and poly addictions and outlines numerous screening and treatment strategies for misuse Covers both the physical and psychological effects of nicotine use and withdrawal to provide a fully-formed view of nicotine dependency and its effects


Book Synopsis Neuroscience of Nicotine by : Victor R. Preedy

Download or read book Neuroscience of Nicotine written by Victor R. Preedy and published by Academic Press. This book was released on 2019-03-20 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroscience of Nicotine: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of nicotine addiction and its effects on the brain. Offering thorough coverage of all aspects of nicotine research, treatment, policy and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of nicotine misuse. With an estimated one billion individuals worldwide classified as tobacco users—and tobacco use often being synonymous with nicotine addiction—nicotine is one of the world’s most common addictive substances, and a frequent comorbidity of misuse of other common addictive substances. Nicotine alters a variety of neurological processes, from molecular biology, to cognition, and quitting is exceedingly difficult because of the number of withdrawal symptoms that accompany the process. Integrates cutting-edge research on the pharmacological, cellular and molecular aspects of nicotine use, along with its effects on neurobiological function Discusses nicotine use as a component of dual-use and poly addictions and outlines numerous screening and treatment strategies for misuse Covers both the physical and psychological effects of nicotine use and withdrawal to provide a fully-formed view of nicotine dependency and its effects

Nicotine Psychopharmacology

Nicotine Psychopharmacology

Author: Jack E. Henningfield

Publisher: Springer Science & Business Media

Published: 2009-02-01

Total Pages: 545

ISBN-13: 3540692487

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The fact that tobacco ingestion can affect how people feel and think has been known for millennia, placing the plant among those used spiritually, honori?cally, and habitually (Corti 1931; Wilbert 1987). However, the conclusion that nicotine - counted for many of these psychopharmacological effects did not emerge until the nineteenth century (Langley 1905). This was elegantly described by Lewin in 1931 as follows: “The decisive factor in the effects of tobacco, desired or undesired, is nicotine. . . ”(Lewin 1998). The use of nicotine as a pharmacological probe to und- stand physiological functioning at the dawn of the twentieth century was a landmark in the birth of modern neuropharmacology (Limbird 2004; Halliwell 2007), and led the pioneering researcher John Langley to conclude that there must exist some “- ceptive substance” to explain the diverse actions of various substances, including nicotine, when applied to muscle tissue (Langley 1905). Research on tobacco and nicotine progressed throughout the twentieth century, but much of this was from a general pharmacological and toxicological rather than a psychopharmacological perspective (Larson et al. 1961). There was some attention to the effects related to addiction, such as euphoria (Johnston 1941), tolerance (Lewin 1931), and withdrawal (Finnegan et al. 1945), but outside of research supported by the tobacco industry, addiction and psychopharmacology were not major foci for research (Slade et al. 1995; Hurt and Robertson 1998; Henning?eld et al. 2006; Henning?eld and Hartel 1999; Larson et al. 1961).


Book Synopsis Nicotine Psychopharmacology by : Jack E. Henningfield

Download or read book Nicotine Psychopharmacology written by Jack E. Henningfield and published by Springer Science & Business Media. This book was released on 2009-02-01 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fact that tobacco ingestion can affect how people feel and think has been known for millennia, placing the plant among those used spiritually, honori?cally, and habitually (Corti 1931; Wilbert 1987). However, the conclusion that nicotine - counted for many of these psychopharmacological effects did not emerge until the nineteenth century (Langley 1905). This was elegantly described by Lewin in 1931 as follows: “The decisive factor in the effects of tobacco, desired or undesired, is nicotine. . . ”(Lewin 1998). The use of nicotine as a pharmacological probe to und- stand physiological functioning at the dawn of the twentieth century was a landmark in the birth of modern neuropharmacology (Limbird 2004; Halliwell 2007), and led the pioneering researcher John Langley to conclude that there must exist some “- ceptive substance” to explain the diverse actions of various substances, including nicotine, when applied to muscle tissue (Langley 1905). Research on tobacco and nicotine progressed throughout the twentieth century, but much of this was from a general pharmacological and toxicological rather than a psychopharmacological perspective (Larson et al. 1961). There was some attention to the effects related to addiction, such as euphoria (Johnston 1941), tolerance (Lewin 1931), and withdrawal (Finnegan et al. 1945), but outside of research supported by the tobacco industry, addiction and psychopharmacology were not major foci for research (Slade et al. 1995; Hurt and Robertson 1998; Henning?eld et al. 2006; Henning?eld and Hartel 1999; Larson et al. 1961).

The Biology of Nicotine Dependence

The Biology of Nicotine Dependence

Author: Gregory R. Bock

Publisher: John Wiley & Sons

Published: 2008-04-30

Total Pages: 274

ISBN-13: 0470513977

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Nicotine is considered to be the main agent in the maintenance of the tobacco smoking habit and is largely responsible for the behavioral and physiological responses to the inhalation of tobacco smoke. This work presents advances made in the elucidation of the action of nicotine in the body--essential information for developing treatments to help people give up smoking. The book reviews the progress made in identifying nicotinic acetylcholine receptors in the brain, using the techniques of molecular biology to characterize receptors and investigate the functional differences between receptors composed of different types of subunits. Sex-specific differences in the response to nicotine, the effects of nicotine on locomotor activity, and its still-debated influence on cognitive performance are considered. The book also examines the habit-forming role of nicotine, the development of tolerance to nicotine, and the less clearly understood phenomenon of withdrawal. Also discusses some potential therapeutic strategies.


Book Synopsis The Biology of Nicotine Dependence by : Gregory R. Bock

Download or read book The Biology of Nicotine Dependence written by Gregory R. Bock and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nicotine is considered to be the main agent in the maintenance of the tobacco smoking habit and is largely responsible for the behavioral and physiological responses to the inhalation of tobacco smoke. This work presents advances made in the elucidation of the action of nicotine in the body--essential information for developing treatments to help people give up smoking. The book reviews the progress made in identifying nicotinic acetylcholine receptors in the brain, using the techniques of molecular biology to characterize receptors and investigate the functional differences between receptors composed of different types of subunits. Sex-specific differences in the response to nicotine, the effects of nicotine on locomotor activity, and its still-debated influence on cognitive performance are considered. The book also examines the habit-forming role of nicotine, the development of tolerance to nicotine, and the less clearly understood phenomenon of withdrawal. Also discusses some potential therapeutic strategies.

Biological Research on Addiction

Biological Research on Addiction

Author: Bernard Le Foll

Publisher: Elsevier Inc. Chapters

Published: 2013-05-17

Total Pages: 758

ISBN-13: 0128065133

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Book Synopsis Biological Research on Addiction by : Bernard Le Foll

Download or read book Biological Research on Addiction written by Bernard Le Foll and published by Elsevier Inc. Chapters. This book was released on 2013-05-17 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Understanding Nicotine and Tobacco Addiction

Understanding Nicotine and Tobacco Addiction

Author: Gregory R. Bock

Publisher: John Wiley & Sons

Published: 2006-06-14

Total Pages: 284

ISBN-13: 0470029226

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Cigarette smoking is estimated to lead to 4.9 million premature deaths per year worldwide. This is predicted to rise to 10 million by 2020. In western countries it kills half of all smokers who fail to stop. The prevailing model for tobacco addiction is that nicotine from cigarettes rewards smoking and punishes abstinence, tapping into a motivational system of operant conditioning that requires no conscious awareness. However, there are also accounts which involve cognitive biases and the effect of nicotine on impulse control. The brain pathways involved have been studied extensively, but the role of different nicotine receptor subtypes and other neurotransmitter systems is still subject to debate. In western countries, cigarette smoking as an adult has a heritability of 30-50% and candidate genes have been identified that may contribute in part to addiction susceptibility. Many socio-cultural correlates of cigarette smoking have been established, but a comprehensive model that accounts for these and links them with the psychobiological aspects of nicotine addiction has not been forthcoming. Structured behavioural support programmes aid cessation attempts, as do a number of pharmacotherapies, most notably nicotine replacement treatments and bupropion, but the underlying mechanisms are unclear. This book deals with the problems involved in understanding and treating nicotine and tobacco addiction. Topics covered include the nature of the worldwide health problem posed by cigarette smoking, the psychodynamics of cigarette addiction, and the basic pharmacology and biochemistry of nicotine and its effect on the brain. Further chapters analyse the genetic basis of susceptibility to nicotine addiction. Finally, the contributors address approaches to therapy. A continuing theme in the discussions throughout the book is how best to treat nicotine addiction, given that many smokers would like to stop smoking but are unable to do so because of their addiction. This book will be of great value to all psychologists and psychiatrists working on addiction, specifically to nicotine but also to other compounds and behaviours. It will also be of interest to neuroscientists and pharmacologists working on nicotine receptors and the brain pathways involved in dependence, as well as to biochemists, molecular biologist and to public health officials.


Book Synopsis Understanding Nicotine and Tobacco Addiction by : Gregory R. Bock

Download or read book Understanding Nicotine and Tobacco Addiction written by Gregory R. Bock and published by John Wiley & Sons. This book was released on 2006-06-14 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cigarette smoking is estimated to lead to 4.9 million premature deaths per year worldwide. This is predicted to rise to 10 million by 2020. In western countries it kills half of all smokers who fail to stop. The prevailing model for tobacco addiction is that nicotine from cigarettes rewards smoking and punishes abstinence, tapping into a motivational system of operant conditioning that requires no conscious awareness. However, there are also accounts which involve cognitive biases and the effect of nicotine on impulse control. The brain pathways involved have been studied extensively, but the role of different nicotine receptor subtypes and other neurotransmitter systems is still subject to debate. In western countries, cigarette smoking as an adult has a heritability of 30-50% and candidate genes have been identified that may contribute in part to addiction susceptibility. Many socio-cultural correlates of cigarette smoking have been established, but a comprehensive model that accounts for these and links them with the psychobiological aspects of nicotine addiction has not been forthcoming. Structured behavioural support programmes aid cessation attempts, as do a number of pharmacotherapies, most notably nicotine replacement treatments and bupropion, but the underlying mechanisms are unclear. This book deals with the problems involved in understanding and treating nicotine and tobacco addiction. Topics covered include the nature of the worldwide health problem posed by cigarette smoking, the psychodynamics of cigarette addiction, and the basic pharmacology and biochemistry of nicotine and its effect on the brain. Further chapters analyse the genetic basis of susceptibility to nicotine addiction. Finally, the contributors address approaches to therapy. A continuing theme in the discussions throughout the book is how best to treat nicotine addiction, given that many smokers would like to stop smoking but are unable to do so because of their addiction. This book will be of great value to all psychologists and psychiatrists working on addiction, specifically to nicotine but also to other compounds and behaviours. It will also be of interest to neuroscientists and pharmacologists working on nicotine receptors and the brain pathways involved in dependence, as well as to biochemists, molecular biologist and to public health officials.

Medication Treatments for Nicotine Dependence

Medication Treatments for Nicotine Dependence

Author: Tony P. George

Publisher: CRC Press

Published: 2006-07-28

Total Pages: 351

ISBN-13: 142000543X

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Despite the prevalence of both pharmaceutical and behavioral approaches to encourage cessation, over a billion people still indulge in tobacco. Even in the U.S., where tobacco use is considered a clearly treatable and socially regrettable condition, a significant percentage of individuals remain resistant to treatment modalities. It is believed tha


Book Synopsis Medication Treatments for Nicotine Dependence by : Tony P. George

Download or read book Medication Treatments for Nicotine Dependence written by Tony P. George and published by CRC Press. This book was released on 2006-07-28 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the prevalence of both pharmaceutical and behavioral approaches to encourage cessation, over a billion people still indulge in tobacco. Even in the U.S., where tobacco use is considered a clearly treatable and socially regrettable condition, a significant percentage of individuals remain resistant to treatment modalities. It is believed tha

The Motivational Impact of Nicotine and its Role in Tobacco Use

The Motivational Impact of Nicotine and its Role in Tobacco Use

Author: Rick A. Bevins

Publisher: Springer Science & Business Media

Published: 2008-12-15

Total Pages: 213

ISBN-13: 0387787496

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More and more scientists are applying the concepts of motivation and related constructs to modify the behavior of drug-addicted and dependent people. Here, authors discuss effective ‘translational’ strategies for decreasing and preventing tobacco use.


Book Synopsis The Motivational Impact of Nicotine and its Role in Tobacco Use by : Rick A. Bevins

Download or read book The Motivational Impact of Nicotine and its Role in Tobacco Use written by Rick A. Bevins and published by Springer Science & Business Media. This book was released on 2008-12-15 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: More and more scientists are applying the concepts of motivation and related constructs to modify the behavior of drug-addicted and dependent people. Here, authors discuss effective ‘translational’ strategies for decreasing and preventing tobacco use.

The Clinical Management of Nicotine Dependence

The Clinical Management of Nicotine Dependence

Author: James A. Cocores

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 347

ISBN-13: 1461391121

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The 1980s have. seen a remarkable degree of public and professional acceptance of cigarette smoking as the most widespread and devastating form of drug dependence. More medical schools now give required courses about drug dependence. Prestigious journals publish reports of investiga tions on the subject of nicotine dependence, and more conferences and workshops are held each year on various aspects of nicotine dependence. All this is in sharp contrast to the earlier prevailing atmosphere of dis interest, ignorance, or professional disdain. These changes created an obvious place for a textbook oriented pri marily toward the needs of clinicians working with patients who have nicotine dependence. Thus, in preparation of this book, most aspects of the management of nicotine dependence are incorporated, in order to address concerns of physicians in training and other health care profes sionals across the world. The final product, which I believe to be com prehensive and clinically relevant throughout, is a text that I hope will be of equal use to psychologists, social workers, nurses, counselors, and physicians in all specialties. An encyclopedic treatise was deliberately avoided because that approach can be cumbersome in size, readability, and cost, and for that reason, readers will find little mention of data involv ing animal research, nicotine-related politics, nicotine product advertising, medical consequences of smoking, psychotherapeutic techniques, and the extent of the problem.


Book Synopsis The Clinical Management of Nicotine Dependence by : James A. Cocores

Download or read book The Clinical Management of Nicotine Dependence written by James A. Cocores and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 1980s have. seen a remarkable degree of public and professional acceptance of cigarette smoking as the most widespread and devastating form of drug dependence. More medical schools now give required courses about drug dependence. Prestigious journals publish reports of investiga tions on the subject of nicotine dependence, and more conferences and workshops are held each year on various aspects of nicotine dependence. All this is in sharp contrast to the earlier prevailing atmosphere of dis interest, ignorance, or professional disdain. These changes created an obvious place for a textbook oriented pri marily toward the needs of clinicians working with patients who have nicotine dependence. Thus, in preparation of this book, most aspects of the management of nicotine dependence are incorporated, in order to address concerns of physicians in training and other health care profes sionals across the world. The final product, which I believe to be com prehensive and clinically relevant throughout, is a text that I hope will be of equal use to psychologists, social workers, nurses, counselors, and physicians in all specialties. An encyclopedic treatise was deliberately avoided because that approach can be cumbersome in size, readability, and cost, and for that reason, readers will find little mention of data involv ing animal research, nicotine-related politics, nicotine product advertising, medical consequences of smoking, psychotherapeutic techniques, and the extent of the problem.