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This book provides an interdisciplinary review of one of the great unsolved mysteries that has fascinated scientists for over 150 years: the origin of chirality in biomolecules. It is fundamental, comprehensive and structured to be accessible for educational purposes.
Book Synopsis The Origin of Chirality in the Molecules of Life (2nd Edition) by : Albert Guijarro
Download or read book The Origin of Chirality in the Molecules of Life (2nd Edition) written by Albert Guijarro and published by Royal Society of Chemistry. This book was released on 2022-06-10 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an interdisciplinary review of one of the great unsolved mysteries that has fascinated scientists for over 150 years: the origin of chirality in biomolecules. It is fundamental, comprehensive and structured to be accessible for educational purposes.
This book provides an interdisciplinary review of one of the great unsolved mysteries that has fascinated scientists for over 150 years: the origin of chirality in biomolecules. It was Pasteur who first initiated the search for a deterministic theory to explain the 'handedness' of biomolecules. His theory, that a 'dissimetric' force was involved, was correct in essence but he never saw the fruits of his labour. Current thinking tells us that asymmetry in the universe has its origins in the forces that unfolded after the Big Bang and, more specifically, the weak force. Being 'left handed', the weak force imprinted its signature on the evolving Universe. However, at the molecular level, the weak force does not provide a straightforward explanation of biomolecular homochirality. In fact, it is yet to be proved beyond doubt that a causal link exists at all. Many alternative theories have been put forward, some of them resting on solid ground, but all lacking definitive experimental evidence to back them up. Some postulate that the handedness of molecules in the biosphere arose by chance but this is hard to test. Others rely on discovering life on similar planets and making comparisons with Earth. Alternative theories have emerged from a range of backgrounds including geology, biology, chemistry, physics and astronomy. Current advances in fields as diverse as space exploration, prebiotic chemistry and high-energy physics may help to provide an answer. Important pieces of information will come from observations at the two frontiers of science: outer space and the subatomic world. Observation of distant planets, galaxies, and even actual sampling of celestial objects from beyond the solar system are projects currently underway. At the other end of the spectrum, there are experiments that study the elemental properties of matter, such as symmetry, and interactions with the fundamental forces. All these efforts will render their fruits soon. This volume unifies all the theories of the origin of biomolecular homochirality together in one source. The various chapters focus on chance mechanisms, physical forces such as the 'weakinteraction', fluid dynamics, amplification of chirality, the organic contents of meteorites and comets and, finally, the physical view of an intrinsically asymmetric universe. This complete, interdisciplinary review of an intriguing subject condenses a large and disparate range of contributions from journals in almost every scientific field. The various theories have been organized, interrelated and explained in a unified way. One of the book's strengths is its extensive use of graphic material to aid understanding the many subjects covered. It is fundamental, comprehensive and structured to be accessible for educational purposes.
Book Synopsis The Origin of Chirality in the Molecules of Life by : Albert Guijarro
Download or read book The Origin of Chirality in the Molecules of Life written by Albert Guijarro and published by Royal Society of Chemistry. This book was released on 2008-11-04 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an interdisciplinary review of one of the great unsolved mysteries that has fascinated scientists for over 150 years: the origin of chirality in biomolecules. It was Pasteur who first initiated the search for a deterministic theory to explain the 'handedness' of biomolecules. His theory, that a 'dissimetric' force was involved, was correct in essence but he never saw the fruits of his labour. Current thinking tells us that asymmetry in the universe has its origins in the forces that unfolded after the Big Bang and, more specifically, the weak force. Being 'left handed', the weak force imprinted its signature on the evolving Universe. However, at the molecular level, the weak force does not provide a straightforward explanation of biomolecular homochirality. In fact, it is yet to be proved beyond doubt that a causal link exists at all. Many alternative theories have been put forward, some of them resting on solid ground, but all lacking definitive experimental evidence to back them up. Some postulate that the handedness of molecules in the biosphere arose by chance but this is hard to test. Others rely on discovering life on similar planets and making comparisons with Earth. Alternative theories have emerged from a range of backgrounds including geology, biology, chemistry, physics and astronomy. Current advances in fields as diverse as space exploration, prebiotic chemistry and high-energy physics may help to provide an answer. Important pieces of information will come from observations at the two frontiers of science: outer space and the subatomic world. Observation of distant planets, galaxies, and even actual sampling of celestial objects from beyond the solar system are projects currently underway. At the other end of the spectrum, there are experiments that study the elemental properties of matter, such as symmetry, and interactions with the fundamental forces. All these efforts will render their fruits soon. This volume unifies all the theories of the origin of biomolecular homochirality together in one source. The various chapters focus on chance mechanisms, physical forces such as the 'weakinteraction', fluid dynamics, amplification of chirality, the organic contents of meteorites and comets and, finally, the physical view of an intrinsically asymmetric universe. This complete, interdisciplinary review of an intriguing subject condenses a large and disparate range of contributions from journals in almost every scientific field. The various theories have been organized, interrelated and explained in a unified way. One of the book's strengths is its extensive use of graphic material to aid understanding the many subjects covered. It is fundamental, comprehensive and structured to be accessible for educational purposes.
Few times an unsolved issue in science has dealt with a larger number of approaches or theories intending to shed light on it and few times this has been done from so different, often orthogonal perspectives. This book covers a hot topic, one of the unsolved problems not just in chemistry, but in science
Book Synopsis The Origin of Chirality in the Molecules of Life by : Albert Guijarro
Download or read book The Origin of Chirality in the Molecules of Life written by Albert Guijarro and published by Royal Society of Chemistry. This book was released on 2008 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few times an unsolved issue in science has dealt with a larger number of approaches or theories intending to shed light on it and few times this has been done from so different, often orthogonal perspectives. This book covers a hot topic, one of the unsolved problems not just in chemistry, but in science
Following on from Advances in BioChirality, Progress in Biological Chirality provides a unique summary and review of the most recent developments in the field of biochirality. Living organisms use only one enantiomer of chiral molecules in the majority of biologically important processes. The exact origin and mechanisms for this surprising selectivity are not yet known. This book discusses current research aimed at identifying the scientific reasons that may contribute to this phenomenon. Progress in Biological Chirality takes an interdisciplinary approach to this exciting field, covering a wide range of topics, such as, theory, palaeontology and food technology, to name but a few. This book presents findings via a broad spectrum of scientific approaches making it an excellent overview of Biological Chirality, suitable for postgraduate students, practitioners and researchers in the field of chemistry, biochemistry, biology, palaeontology, and food science with an interest in Chirality. This book contains 32 chapters written by Authors, who are leading authorities in the field Presents the most recent research taking place in this highly challenging field Contains both reference material for the specialist and provides an overview for those who are interested in the fundamental problems of biology and chemistry
Book Synopsis Progress in Biological Chirality by : Gyula Palyi
Download or read book Progress in Biological Chirality written by Gyula Palyi and published by Elsevier. This book was released on 2004-12-13 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following on from Advances in BioChirality, Progress in Biological Chirality provides a unique summary and review of the most recent developments in the field of biochirality. Living organisms use only one enantiomer of chiral molecules in the majority of biologically important processes. The exact origin and mechanisms for this surprising selectivity are not yet known. This book discusses current research aimed at identifying the scientific reasons that may contribute to this phenomenon. Progress in Biological Chirality takes an interdisciplinary approach to this exciting field, covering a wide range of topics, such as, theory, palaeontology and food technology, to name but a few. This book presents findings via a broad spectrum of scientific approaches making it an excellent overview of Biological Chirality, suitable for postgraduate students, practitioners and researchers in the field of chemistry, biochemistry, biology, palaeontology, and food science with an interest in Chirality. This book contains 32 chapters written by Authors, who are leading authorities in the field Presents the most recent research taking place in this highly challenging field Contains both reference material for the specialist and provides an overview for those who are interested in the fundamental problems of biology and chemistry
Creating the Molecules of Life discusses origins, including the Big Bang, and the origin of the elements. With a complete presentation and explanation, this book provides evidence that the molecules of life are produced in outer space and how the SNAAP model purports to explain that origin. Extremophiles, which explains that evolution is robust enough to create life forms in a wide variety of conditions, is also presented. Readable for those at the upper undergraduate level, mathematics associated with coupling the nuclear spins to the molecular chirality is discussed. An accompanied appendix is provided to support mathematics.
Book Synopsis Creating the Molecules of Life by : Richard N. Boyd
Download or read book Creating the Molecules of Life written by Richard N. Boyd and published by Iph001. This book was released on 2019-03-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Creating the Molecules of Life discusses origins, including the Big Bang, and the origin of the elements. With a complete presentation and explanation, this book provides evidence that the molecules of life are produced in outer space and how the SNAAP model purports to explain that origin. Extremophiles, which explains that evolution is robust enough to create life forms in a wide variety of conditions, is also presented. Readable for those at the upper undergraduate level, mathematics associated with coupling the nuclear spins to the molecular chirality is discussed. An accompanied appendix is provided to support mathematics.
Annotation Papers from the February 1995 conference explore questions of the necessity of homochiral structure, the homochiral prebiotic medium hypothesis, the potential of homochirality to be used as a signature for existing or previous living systems beyond Earth, and experiments seeking to clarify the origin of homochirality. Contains sections on historical perspective, homochirality and life, models of physical chiral symmetry breaking, and future tests. For chemists, chemical physicists, and astrophysicists. No index. Annotation c. by Book News, Inc., Portland, Or.
Book Synopsis The Physical Origin of Homochirality in Life by : David Cline
Download or read book The Physical Origin of Homochirality in Life written by David Cline and published by American Institute of Physics. This book was released on 1996 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation Papers from the February 1995 conference explore questions of the necessity of homochiral structure, the homochiral prebiotic medium hypothesis, the potential of homochirality to be used as a signature for existing or previous living systems beyond Earth, and experiments seeking to clarify the origin of homochirality. Contains sections on historical perspective, homochirality and life, models of physical chiral symmetry breaking, and future tests. For chemists, chemical physicists, and astrophysicists. No index. Annotation c. by Book News, Inc., Portland, Or.
The origin of life from inanimate matter has been the focus of much research for decades, both experimentally and philosophically. Luisi takes the reader through the consecutive stages from prebiotic chemistry to synthetic biology, uniquely combining both approaches. This book presents a systematic course discussing the successive stages of self-organisation, emergence, self-replication, autopoiesis, synthetic compartments and construction of cellular models, in order to demonstrate the spontaneous increase in complexity from inanimate matter to the first cellular life forms. A chapter is dedicated to each of these steps, using a number of synthetic and biological examples. With end-of-chapter review questions to aid reader comprehension, this book will appeal to graduate students and academics researching the origin of life and related areas such as evolutionary biology, biochemistry, molecular biology, biophysics and natural sciences.
Book Synopsis The Emergence of Life by : Pier Luigi Luisi
Download or read book The Emergence of Life written by Pier Luigi Luisi and published by Cambridge University Press. This book was released on 2006-07-13 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: The origin of life from inanimate matter has been the focus of much research for decades, both experimentally and philosophically. Luisi takes the reader through the consecutive stages from prebiotic chemistry to synthetic biology, uniquely combining both approaches. This book presents a systematic course discussing the successive stages of self-organisation, emergence, self-replication, autopoiesis, synthetic compartments and construction of cellular models, in order to demonstrate the spontaneous increase in complexity from inanimate matter to the first cellular life forms. A chapter is dedicated to each of these steps, using a number of synthetic and biological examples. With end-of-chapter review questions to aid reader comprehension, this book will appeal to graduate students and academics researching the origin of life and related areas such as evolutionary biology, biochemistry, molecular biology, biophysics and natural sciences.
This book presents the fascinating formation of the first simple bioorganic molecules and describes the hidden aspects of chiral compounds, which raise questions on the molecular beginnings of life. The occurrences of extraterrestrial, non-standard amino acids in meteorites are dealt with in detail, as well as their subsequent transfer to proteinogenic amino acids. The concept of asymmetric organo-catalysis for the synthesis of carbohydrates and ribonucleosides are considered. The notion of a single amino acid that functions as an enzyme is developed. Attempts to simulate ancient world scenarios are critically reviewed. There is a special focus on ribozymes and the resulting RNA world. Combinations of different world scenarios are discussed in view of an on-going evolution. The currently most plausible hypotheses and visions of ancient world scenarios that led to today’s DNA world are also provided. Included is a pre-cellular world of viruses that is presented for the first time.
Book Synopsis Chirality and Life by : Rolf M. Flügel
Download or read book Chirality and Life written by Rolf M. Flügel and published by Springer Science & Business Media. This book was released on 2011-01-11 with total page 66 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the fascinating formation of the first simple bioorganic molecules and describes the hidden aspects of chiral compounds, which raise questions on the molecular beginnings of life. The occurrences of extraterrestrial, non-standard amino acids in meteorites are dealt with in detail, as well as their subsequent transfer to proteinogenic amino acids. The concept of asymmetric organo-catalysis for the synthesis of carbohydrates and ribonucleosides are considered. The notion of a single amino acid that functions as an enzyme is developed. Attempts to simulate ancient world scenarios are critically reviewed. There is a special focus on ribozymes and the resulting RNA world. Combinations of different world scenarios are discussed in view of an on-going evolution. The currently most plausible hypotheses and visions of ancient world scenarios that led to today’s DNA world are also provided. Included is a pre-cellular world of viruses that is presented for the first time.
Book Synopsis The Origins of Life: Molecules and Natural Selection by : Leslie E. Orgel
Download or read book The Origins of Life: Molecules and Natural Selection written by Leslie E. Orgel and published by John Wiley & Sons. This book was released on 1973 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:
The only standard reference in this exciting new field combines the physical, chemical and material science perspectives in a synergic way. This monograph traces the development of the preparative methods employed to create nanostructures, in addition to the experimental techniques used to characterize them, as well as some of the surprising physical effects. The chapters cover every category of material, from organic to coordination compounds, metals and composites, in zero, one, two and three dimensions. The book also reviews structural, chemical, optical, and other physical properties, finishing with a look at the future for chiral nanosystems.
Book Synopsis Chirality at the Nanoscale by : David B. Amabilino
Download or read book Chirality at the Nanoscale written by David B. Amabilino and published by John Wiley & Sons. This book was released on 2009-02-11 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only standard reference in this exciting new field combines the physical, chemical and material science perspectives in a synergic way. This monograph traces the development of the preparative methods employed to create nanostructures, in addition to the experimental techniques used to characterize them, as well as some of the surprising physical effects. The chapters cover every category of material, from organic to coordination compounds, metals and composites, in zero, one, two and three dimensions. The book also reviews structural, chemical, optical, and other physical properties, finishing with a look at the future for chiral nanosystems.
