Transmissible Spongiform Encephalopathies in the United States

Transmissible Spongiform Encephalopathies in the United States

Author:

Publisher:

Published: 2000

Total Pages: 52

ISBN-13:

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Download or read book Transmissible Spongiform Encephalopathies in the United States written by and published by . This book was released on 2000 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Neurogenetics

Neurogenetics

Author:

Publisher: Elsevier

Published: 2018-01-09

Total Pages: 480

ISBN-13: 0444640770

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Neurogenetics, Part II, Volume 148, the latest release in the Handbook of Clinical Neurology, provides the latest information on the genetic methodologies that are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is expected to dramatically grow in scope. Part II builds on the foundation of Part I, expanding the coverage to dementias, paroxysmal disorders, neuromuscular disorders, white matter and demyelination diseases, cerebrovascular diseases, adult psychiatric disorders and cancer and phacomatoses. Contains comprehensive coverage of neurogenetics Details the latest science and its impact on our understanding of neurological, psychiatric disorders Presents a focused reference for clinical practitioners and the neuroscience/neurogenetics research community


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Download or read book Neurogenetics written by and published by Elsevier. This book was released on 2018-01-09 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurogenetics, Part II, Volume 148, the latest release in the Handbook of Clinical Neurology, provides the latest information on the genetic methodologies that are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is expected to dramatically grow in scope. Part II builds on the foundation of Part I, expanding the coverage to dementias, paroxysmal disorders, neuromuscular disorders, white matter and demyelination diseases, cerebrovascular diseases, adult psychiatric disorders and cancer and phacomatoses. Contains comprehensive coverage of neurogenetics Details the latest science and its impact on our understanding of neurological, psychiatric disorders Presents a focused reference for clinical practitioners and the neuroscience/neurogenetics research community


Advancing Prion Science

Advancing Prion Science

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2003-03-20

Total Pages: 125

ISBN-13: 0309168597

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In Advancing Prion Science, the Institute of Medicine's Committee on Transmissible Spongiform Encephalopathies Assessment of Relevant Science recommends priorities for research and investment to the Department of Defense's National Prion Research Program (NPRP). Transmissible spongiform encephalopathies (TSEs), also called prion diseases, are invariably fatal neurodegenerative infectious diseases that include bovine spongiform encephalopathy (commonly called mad cow disease), chronic wasting disease, scrapie, and Creutzfeldt-Jakob disease. To develop antemortem diagnostics or therapies for TSEs, the committee concludes that NPRP should invest in basic research specifically to elucidate the structural features of prions, the molecular mechanisms of prion replication, the mechanisms of TSE pathogenesis, and the physiological function of prions' normal cellular isoform. Advancing Prion Science provides the first comprehensive reference on present knowledge about all aspects of TSEs' from basic science to the U.S. research infrastructure, from diagnostics to surveillance, and from prevention to treatment. This report summarizes the progress thus far.


Book Synopsis Advancing Prion Science by : Institute of Medicine

Download or read book Advancing Prion Science written by Institute of Medicine and published by National Academies Press. This book was released on 2003-03-20 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Advancing Prion Science, the Institute of Medicine's Committee on Transmissible Spongiform Encephalopathies Assessment of Relevant Science recommends priorities for research and investment to the Department of Defense's National Prion Research Program (NPRP). Transmissible spongiform encephalopathies (TSEs), also called prion diseases, are invariably fatal neurodegenerative infectious diseases that include bovine spongiform encephalopathy (commonly called mad cow disease), chronic wasting disease, scrapie, and Creutzfeldt-Jakob disease. To develop antemortem diagnostics or therapies for TSEs, the committee concludes that NPRP should invest in basic research specifically to elucidate the structural features of prions, the molecular mechanisms of prion replication, the mechanisms of TSE pathogenesis, and the physiological function of prions' normal cellular isoform. Advancing Prion Science provides the first comprehensive reference on present knowledge about all aspects of TSEs' from basic science to the U.S. research infrastructure, from diagnostics to surveillance, and from prevention to treatment. This report summarizes the progress thus far.


Potential Transmission of Spongiform Encephalopathies to Humans

Potential Transmission of Spongiform Encephalopathies to Humans

Author: United States. Congress. House. Committee on Government Reform and Oversight

Publisher:

Published: 1997

Total Pages: 270

ISBN-13:

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Download or read book Potential Transmission of Spongiform Encephalopathies to Humans written by United States. Congress. House. Committee on Government Reform and Oversight and published by . This book was released on 1997 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Surveillance and Diagnosis of Transmissible Spongiform Encephalopathies in the United States

Surveillance and Diagnosis of Transmissible Spongiform Encephalopathies in the United States

Author: Michelle Marie Dennis

Publisher:

Published: 2007

Total Pages: 574

ISBN-13:

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Book Synopsis Surveillance and Diagnosis of Transmissible Spongiform Encephalopathies in the United States by : Michelle Marie Dennis

Download or read book Surveillance and Diagnosis of Transmissible Spongiform Encephalopathies in the United States written by Michelle Marie Dennis and published by . This book was released on 2007 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Human Prion Diseases

Human Prion Diseases

Author:

Publisher: Elsevier

Published: 2018-06-07

Total Pages: 512

ISBN-13: 0444639535

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Human Prion Diseases, Volume 153 is designed to update the reader on the latest advances and clinical aspects of prion diseases. The book is organized into five sections, including the pathophysiology of prions and a description of animal and human diseases. This is followed by detailed reports on recent advances in diagnosis strategies for the development of novel anti-prion molecules and possible designs of clinical trials in such a rare disease. An introductory chapter gives an extensive historical background of prion research, with a final chapter highlighting recent progress, and more importantly, unsolved problems. Offers an authoritative overview of prion diseases in humans, detailing the pathogenesis of the disease, clinical investigations, and the diagnosis of both the genetic and acquired forms Provides clarity and context by presenting prion diseases in relation to other neurodegenerative diseases in humans Emphasizes the unique properties of prion diseases and consequent problems they can cause, both clinically and in public health terms


Book Synopsis Human Prion Diseases by :

Download or read book Human Prion Diseases written by and published by Elsevier. This book was released on 2018-06-07 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Prion Diseases, Volume 153 is designed to update the reader on the latest advances and clinical aspects of prion diseases. The book is organized into five sections, including the pathophysiology of prions and a description of animal and human diseases. This is followed by detailed reports on recent advances in diagnosis strategies for the development of novel anti-prion molecules and possible designs of clinical trials in such a rare disease. An introductory chapter gives an extensive historical background of prion research, with a final chapter highlighting recent progress, and more importantly, unsolved problems. Offers an authoritative overview of prion diseases in humans, detailing the pathogenesis of the disease, clinical investigations, and the diagnosis of both the genetic and acquired forms Provides clarity and context by presenting prion diseases in relation to other neurodegenerative diseases in humans Emphasizes the unique properties of prion diseases and consequent problems they can cause, both clinically and in public health terms


How the Cows Turned Mad

How the Cows Turned Mad

Author: Maxime Schwartz

Publisher: Univ of California Press

Published: 2004-09-13

Total Pages: 264

ISBN-13: 0520243374

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"How the Cows Turned Mad tells the story of a disease that continues to elude on many levels. Yet science has come far in understanding its origins, incubation, and transmission. This book is a case history that illuminates the remarkable progression of science."--BOOK JACKET.


Book Synopsis How the Cows Turned Mad by : Maxime Schwartz

Download or read book How the Cows Turned Mad written by Maxime Schwartz and published by Univ of California Press. This book was released on 2004-09-13 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: "How the Cows Turned Mad tells the story of a disease that continues to elude on many levels. Yet science has come far in understanding its origins, incubation, and transmission. This book is a case history that illuminates the remarkable progression of science."--BOOK JACKET.


Transmissible Spongiform Encephalopathies (TSEs), Including "Mad Cow Disease"

Transmissible Spongiform Encephalopathies (TSEs), Including

Author:

Publisher:

Published: 2004

Total Pages: 0

ISBN-13:

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On December 23, 2003, the U.S. Secretary of Agriculture announced that a cow in Washington state had tested positive for bovine spongiform encephalopathy (BSE, or Mad Cow disease), representing the first domestic case. The Secretary announced expanded protections against BSE on December 30, 2003. On January 26, 2004, the U.S. Secretary of Health and Human Services announced additional safety measures for products regulated by the U.S. Food and Drug Administration (FDA) to protect public health. Both have stressed that the human health impact of finding one BSE positive cow is believed to be minimal. BSE is a member of a group of diseases called Transmissible Spongiform Encephalopathies (TSEs). Although the predominant theory is that TSEs are caused by prions or proteinaceous infectious particles (a novel disease mechanism first described in the 1980s), some scientists believe a virus may eventually be identified as the infectious agent. While some TSEs, such as scrapie in sheep, have been known for over 200 years, others, including BSE, appear to have emerged quite recently. Some TSEs seem to affect only one species and others, like BSE, appear to have jumped the "species barrier" to infect more than one species. This event has transformed prion diseases from a rare and esoteric area of research to a matter of significant public health concern. BSE is believed to have been transmitted to people who ate contaminated beef, leading to the identification in 1996 of a new human disease, variant Creutzfeld-Jakob disease (vCJD), in the United Kingdom. As attention has focused on the finding of BSE in the United States, government control efforts have been scrutinized. Some have argued that prevention programs, begun in 1988 and strengthened at points since then, are robust, and that the finding of a BSE-positive cow represents an isolated case and a negligible health risk to humans. Others believe that shortfalls in government prevention efforts are serious, and that BSE may be entrenched in the United States, albeit at low levels. The spectrum of opinions about the public health risk from BSE underscores the myriad uncertainties surrounding prion diseases, and especially their modes of transmission, and detection. This report examines known and purported human health risks from BSE and related diseases, the status of efforts to detect and prevent these diseases in humans, and the scientific basis of these efforts. For a discussion of BSE prevention efforts in the agricultural sector (including FDA measures to assure the safety of animal feed, and USDA measures to assure the safety of beef), refer to CRS Issue Brief IB10127, Mad Cow Disease: Agricultural Issues for Congress, by Geoffrey S. Becker, and CRS Report RL32199, Bovine Spongiform Encephalopathy (BSE, or 'Mad Cow Disease'): Current and Proposed Safeguards, by Sarah A. Lister and Geoffrey S. Becker. This report will be updated as circumstances warrant.


Book Synopsis Transmissible Spongiform Encephalopathies (TSEs), Including "Mad Cow Disease" by :

Download or read book Transmissible Spongiform Encephalopathies (TSEs), Including "Mad Cow Disease" written by and published by . This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: On December 23, 2003, the U.S. Secretary of Agriculture announced that a cow in Washington state had tested positive for bovine spongiform encephalopathy (BSE, or Mad Cow disease), representing the first domestic case. The Secretary announced expanded protections against BSE on December 30, 2003. On January 26, 2004, the U.S. Secretary of Health and Human Services announced additional safety measures for products regulated by the U.S. Food and Drug Administration (FDA) to protect public health. Both have stressed that the human health impact of finding one BSE positive cow is believed to be minimal. BSE is a member of a group of diseases called Transmissible Spongiform Encephalopathies (TSEs). Although the predominant theory is that TSEs are caused by prions or proteinaceous infectious particles (a novel disease mechanism first described in the 1980s), some scientists believe a virus may eventually be identified as the infectious agent. While some TSEs, such as scrapie in sheep, have been known for over 200 years, others, including BSE, appear to have emerged quite recently. Some TSEs seem to affect only one species and others, like BSE, appear to have jumped the "species barrier" to infect more than one species. This event has transformed prion diseases from a rare and esoteric area of research to a matter of significant public health concern. BSE is believed to have been transmitted to people who ate contaminated beef, leading to the identification in 1996 of a new human disease, variant Creutzfeld-Jakob disease (vCJD), in the United Kingdom. As attention has focused on the finding of BSE in the United States, government control efforts have been scrutinized. Some have argued that prevention programs, begun in 1988 and strengthened at points since then, are robust, and that the finding of a BSE-positive cow represents an isolated case and a negligible health risk to humans. Others believe that shortfalls in government prevention efforts are serious, and that BSE may be entrenched in the United States, albeit at low levels. The spectrum of opinions about the public health risk from BSE underscores the myriad uncertainties surrounding prion diseases, and especially their modes of transmission, and detection. This report examines known and purported human health risks from BSE and related diseases, the status of efforts to detect and prevent these diseases in humans, and the scientific basis of these efforts. For a discussion of BSE prevention efforts in the agricultural sector (including FDA measures to assure the safety of animal feed, and USDA measures to assure the safety of beef), refer to CRS Issue Brief IB10127, Mad Cow Disease: Agricultural Issues for Congress, by Geoffrey S. Becker, and CRS Report RL32199, Bovine Spongiform Encephalopathy (BSE, or 'Mad Cow Disease'): Current and Proposed Safeguards, by Sarah A. Lister and Geoffrey S. Becker. This report will be updated as circumstances warrant.


Transmissible Spongiform Encephalopathies

Transmissible Spongiform Encephalopathies

Author: European Commission. Directorate General for Research

Publisher:

Published: 2007

Total Pages: 58

ISBN-13:

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This booklet highlights the research response of the European Commission to the spectrum of diseases known as the Transmissible Spongiform Encephalopathies (TSEs), which include BSE (primarily a disease of cattle), scrapie in sheep and goats (small ruminants) and variant and classical or sporadic CJD in man. It also provides information on three of the larger research programmes carried out in Member States of the European Union. The booklet focuses on key projects funded by the Directorate-General for Research from the mid 1990s to the present day, and in doing so, aims to give an overview of the important work carried out in the past, as well as of current research priorities.


Book Synopsis Transmissible Spongiform Encephalopathies by : European Commission. Directorate General for Research

Download or read book Transmissible Spongiform Encephalopathies written by European Commission. Directorate General for Research and published by . This book was released on 2007 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt: This booklet highlights the research response of the European Commission to the spectrum of diseases known as the Transmissible Spongiform Encephalopathies (TSEs), which include BSE (primarily a disease of cattle), scrapie in sheep and goats (small ruminants) and variant and classical or sporadic CJD in man. It also provides information on three of the larger research programmes carried out in Member States of the European Union. The booklet focuses on key projects funded by the Directorate-General for Research from the mid 1990s to the present day, and in doing so, aims to give an overview of the important work carried out in the past, as well as of current research priorities.


Mad Cows and Cannibals

Mad Cows and Cannibals

Author: Charlotte A. Spencer

Publisher: Prentice Hall

Published: 2004

Total Pages: 0

ISBN-13: 9780131423398

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Part of the Prentice Hall Exploring Biology Series, Mad Cows and Cannibals explores the biological, political and social aspects of transmissible spongiform encephalopathies, including Mad Cow Disease and Chronic Wasting Disease. The text begins with stories of ritualistic cannibalism in the highlands of New Guinea, and leads to the modern agricultural feeding practices that triggered the Mad Cow Disease epidemic in Great Britain, and to recent outbreaks of Chronic Wasting Disease in North America. In clear and accessible language, it explains the biology of these bizzare, degenerative brain diseases, answering important questions about how TSEs affect the safety of our food supply, blood supply, and medical procedures.


Book Synopsis Mad Cows and Cannibals by : Charlotte A. Spencer

Download or read book Mad Cows and Cannibals written by Charlotte A. Spencer and published by Prentice Hall. This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the Prentice Hall Exploring Biology Series, Mad Cows and Cannibals explores the biological, political and social aspects of transmissible spongiform encephalopathies, including Mad Cow Disease and Chronic Wasting Disease. The text begins with stories of ritualistic cannibalism in the highlands of New Guinea, and leads to the modern agricultural feeding practices that triggered the Mad Cow Disease epidemic in Great Britain, and to recent outbreaks of Chronic Wasting Disease in North America. In clear and accessible language, it explains the biology of these bizzare, degenerative brain diseases, answering important questions about how TSEs affect the safety of our food supply, blood supply, and medical procedures.