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Reveals the nature and extent of the damage done to the British intelligence establishment during the Second World War by the 'Cambridge Five' spy ring: Kim Philby, Donald Maclean, Guy Burgess, Anthony Blunt and John Cairncross.
Book Synopsis TRIPLEX by : Nigel West
Download or read book TRIPLEX written by Nigel West and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reveals the nature and extent of the damage done to the British intelligence establishment during the Second World War by the 'Cambridge Five' spy ring: Kim Philby, Donald Maclean, Guy Burgess, Anthony Blunt and John Cairncross.
Inhaltsangabe:Introduction: Breast Cancer: Cancer describes a group of various diseases, where cells start changing their molecular structure and begin to grow and to supersede normal cells. Cancer is induced by numerous different elicitors, which finally all lead to an interference of the genetically regulated balance between cell cycle and apoptosis. Although every organ in the human body can be afflicted with cancer, there are significant differences in frequency relating amongst others to age, sex, geographic region and personal habits. In the industrialized countries, breast cancer is the leading cause of death for women at the age between 30 and 60 years. With estimated 636.000 incident cases in the developed countries and 514.000 in the developing countries, breast cancer is the most prevalent cancer type among woman worldwide. Once detected, the cancer is classified based upon pathological characterizations of the tumor or a biopsy and the lymph nodes. A clinical way of characterizing the tumor is the TNM-classification, which describes the size of the tumor (T), the number of affected lymph nodes (N) and the existence of distant metastases (M). The histological classification characterizes the carcinoma according to its structural and cellular appearance and the amitosis rate leading to a grading from 1 to 3. An immuno-histological examination provides information about the estrogen- and the progesterone-receptor- and about the Her-2/neu-status. Breast cancer is a very heterogeneous disease. There are basic classifications that are unquestioned, even today. Recent studies confirmed the need to determine well known markers (i.e. estrogen (ER) and progesterone (PR) receptor status or HER2 status), but the large variety of subtypes and the corresponding different molecular pattern impede a uniform treatment. Although already today other factors than anatomical classifications are being taken into consideration, there exists a need for further biological markers to assist the physician in charge with his evaluation. Beside the diagnostic recognition, the choice of appropriate therapy and the prediction of prognosis are goals that should be reached in order to prevent early stage cancer patients from therapies that provide minimal benefit but reduce their quality of life by intense adverse reactions. RNA Expression Profiling and Prediction: Already today there are numerous genes associated with breast cancer occurrence, therapy [...]
Book Synopsis Multiplexing of Singleplex Real-Time-PCR Assays into Duplexes and Triplexes by : Patrick Maaß
Download or read book Multiplexing of Singleplex Real-Time-PCR Assays into Duplexes and Triplexes written by Patrick Maaß and published by diplom.de. This book was released on 2011-05-16 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inhaltsangabe:Introduction: Breast Cancer: Cancer describes a group of various diseases, where cells start changing their molecular structure and begin to grow and to supersede normal cells. Cancer is induced by numerous different elicitors, which finally all lead to an interference of the genetically regulated balance between cell cycle and apoptosis. Although every organ in the human body can be afflicted with cancer, there are significant differences in frequency relating amongst others to age, sex, geographic region and personal habits. In the industrialized countries, breast cancer is the leading cause of death for women at the age between 30 and 60 years. With estimated 636.000 incident cases in the developed countries and 514.000 in the developing countries, breast cancer is the most prevalent cancer type among woman worldwide. Once detected, the cancer is classified based upon pathological characterizations of the tumor or a biopsy and the lymph nodes. A clinical way of characterizing the tumor is the TNM-classification, which describes the size of the tumor (T), the number of affected lymph nodes (N) and the existence of distant metastases (M). The histological classification characterizes the carcinoma according to its structural and cellular appearance and the amitosis rate leading to a grading from 1 to 3. An immuno-histological examination provides information about the estrogen- and the progesterone-receptor- and about the Her-2/neu-status. Breast cancer is a very heterogeneous disease. There are basic classifications that are unquestioned, even today. Recent studies confirmed the need to determine well known markers (i.e. estrogen (ER) and progesterone (PR) receptor status or HER2 status), but the large variety of subtypes and the corresponding different molecular pattern impede a uniform treatment. Although already today other factors than anatomical classifications are being taken into consideration, there exists a need for further biological markers to assist the physician in charge with his evaluation. Beside the diagnostic recognition, the choice of appropriate therapy and the prediction of prognosis are goals that should be reached in order to prevent early stage cancer patients from therapies that provide minimal benefit but reduce their quality of life by intense adverse reactions. RNA Expression Profiling and Prediction: Already today there are numerous genes associated with breast cancer occurrence, therapy [...]
Download or read book Motor World Wholesale written by and published by . This book was released on 1912 with total page 1148 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Motor World written by and published by . This book was released on 1912 with total page 1120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Steam Pumps by : Knowles Steam Pump Works
Download or read book Steam Pumps written by Knowles Steam Pump Works and published by . This book was released on 1898 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Automobile Dealer and Repairer written by and published by . This book was released on 1912 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Electric Power on the Farm by : Adolph Shane
Download or read book Electric Power on the Farm written by Adolph Shane and published by . This book was released on 1911 with total page 1120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Principles of Nucleic Acid Structure, Second Edition, provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussions of X-ray crystallography, NMR, molecular modelling and databases. The book's focus is on a survey of structures that are especially important for biomedical research and pharmacological applications. This updated edition includes the latest advances relevant to recognition of DNA and RNA by small molecules and proteins, including sections on RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes and short interfering RNA (siRNA). This reference is a must-have for those seeking an authoritative, comprehensive and up-to-date source on all aspects of nucleic acid structure, from basic first principles to details of recent research results. Completely updated, with an expanded section on protein-nucleic acid interactions that reflects major increases in our knowledge Defines technical terms for novices Includes a complete list of resources, including relevant online databases and software, as well as useful websites
Book Synopsis Principles of Nucleic Acid Structure by : Stephen Neidle
Download or read book Principles of Nucleic Acid Structure written by Stephen Neidle and published by Academic Press. This book was released on 2021-10-15 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Nucleic Acid Structure, Second Edition, provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussions of X-ray crystallography, NMR, molecular modelling and databases. The book's focus is on a survey of structures that are especially important for biomedical research and pharmacological applications. This updated edition includes the latest advances relevant to recognition of DNA and RNA by small molecules and proteins, including sections on RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes and short interfering RNA (siRNA). This reference is a must-have for those seeking an authoritative, comprehensive and up-to-date source on all aspects of nucleic acid structure, from basic first principles to details of recent research results. Completely updated, with an expanded section on protein-nucleic acid interactions that reflects major increases in our knowledge Defines technical terms for novices Includes a complete list of resources, including relevant online databases and software, as well as useful websites
Book Synopsis Bulletin by : Iowa Engineering Experiment Station
Download or read book Bulletin written by Iowa Engineering Experiment Station and published by . This book was released on 1915 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book American Motorist written by and published by . This book was released on 1912 with total page 1076 pages. Available in PDF, EPUB and Kindle. Book excerpt: