Understanding Radiation Biology

Understanding Radiation Biology

Author: Kenneth Chadwick

Publisher: CRC Press

Published: 2019-11-15

Total Pages: 241

ISBN-13: 1000733882

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This book provides a qualitative and quantitative exploration of the action of radiation on living matter which leads to a complete and coherent interpretation of radiation biology. It takes readers from radiation-induced molecular damage in the nucleus of the cell and links this damage to cellular effects such as cell killing, chromosome aberrations and mutations before exploring organ damage, organism lethality and cancer induction. It also deals with radiological protection concepts and the difficulties of predicting the dose–effect relationship for low-dose and dose rate radiation risk. The book ends with separate chapters dealing with the effects of UV light exposure and risk classification of chemical mutagens, both of which are derived by logical extensions of the radiation model. This book will provide the basic foundations of radiation biology for undergraduate and graduate students in medical physics, biomedical engineering, radiological protection, medicine, radiology and radiography. Features Presents a comprehensive insight into radiation action on living matter Contains important implications for radiological protection and regulations Provides analytical methods for applications in radiotherapy


Book Synopsis Understanding Radiation Biology by : Kenneth Chadwick

Download or read book Understanding Radiation Biology written by Kenneth Chadwick and published by CRC Press. This book was released on 2019-11-15 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a qualitative and quantitative exploration of the action of radiation on living matter which leads to a complete and coherent interpretation of radiation biology. It takes readers from radiation-induced molecular damage in the nucleus of the cell and links this damage to cellular effects such as cell killing, chromosome aberrations and mutations before exploring organ damage, organism lethality and cancer induction. It also deals with radiological protection concepts and the difficulties of predicting the dose–effect relationship for low-dose and dose rate radiation risk. The book ends with separate chapters dealing with the effects of UV light exposure and risk classification of chemical mutagens, both of which are derived by logical extensions of the radiation model. This book will provide the basic foundations of radiation biology for undergraduate and graduate students in medical physics, biomedical engineering, radiological protection, medicine, radiology and radiography. Features Presents a comprehensive insight into radiation action on living matter Contains important implications for radiological protection and regulations Provides analytical methods for applications in radiotherapy

Adverse Reproductive Outcomes in Families of Atomic Veterans

Adverse Reproductive Outcomes in Families of Atomic Veterans

Author: Institute of Medicine

Publisher: National Academies Press

Published: 1995-07-17

Total Pages: 107

ISBN-13: 0309176115

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Over the past several decades, public concern over exposure to ionizing radiation has increased. This concern has manifested itself in different ways depending on the perception of risk to different individuals and different groups and the circumstances of their exposure. One such group are those U.S. servicemen (the "Atomic Veterans" who participated in the atmospheric testing of nuclear weapons at the Nevada Test Site or in the Pacific Proving Grounds, who served with occupation forces in or near Hiroshima and Nagasaki, or who were prisoners of war in or near those cities at the time of, or shortly after, the atomic bombings. This book addresses the feasibility of conducting an epidemiologic study to determine if there is an increased risk of adverse reproductive outcomes in the spouses, children, and grandchildren of the Atomic Veterans.


Book Synopsis Adverse Reproductive Outcomes in Families of Atomic Veterans by : Institute of Medicine

Download or read book Adverse Reproductive Outcomes in Families of Atomic Veterans written by Institute of Medicine and published by National Academies Press. This book was released on 1995-07-17 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past several decades, public concern over exposure to ionizing radiation has increased. This concern has manifested itself in different ways depending on the perception of risk to different individuals and different groups and the circumstances of their exposure. One such group are those U.S. servicemen (the "Atomic Veterans" who participated in the atmospheric testing of nuclear weapons at the Nevada Test Site or in the Pacific Proving Grounds, who served with occupation forces in or near Hiroshima and Nagasaki, or who were prisoners of war in or near those cities at the time of, or shortly after, the atomic bombings. This book addresses the feasibility of conducting an epidemiologic study to determine if there is an increased risk of adverse reproductive outcomes in the spouses, children, and grandchildren of the Atomic Veterans.

Understanding Radiation Science

Understanding Radiation Science

Author: James Mannie Shuler

Publisher: Universal-Publishers

Published: 2006

Total Pages: 121

ISBN-13: 1581129076

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The purpose of Understanding Radiation Science: Basic Nuclear and Health Physics is to provide the reader a basic understanding of radiation science. Therefore, basic nuclear physics and health physics principles are presented through chapters on atomic structure, types of radiation, terminology and units, radiation biology, exposure and controls, background radiation, personnel monitoring, and radiation instrumentation. The book concludes with chapters on historical events and definitions. This book provides introductory information for students starting their education in nuclear physics, health physics and nuclear engineering. The material covered in this book is appropriate for all types of radiation workers. Persons studying to take the health physics certification exam, radiation protection technologist exam, or the certifying examinations to become radiologic technologists, radiation therapy technologists, ultrasound technologists, or nuclear medicine technologists will find this information most useful.


Book Synopsis Understanding Radiation Science by : James Mannie Shuler

Download or read book Understanding Radiation Science written by James Mannie Shuler and published by Universal-Publishers. This book was released on 2006 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of Understanding Radiation Science: Basic Nuclear and Health Physics is to provide the reader a basic understanding of radiation science. Therefore, basic nuclear physics and health physics principles are presented through chapters on atomic structure, types of radiation, terminology and units, radiation biology, exposure and controls, background radiation, personnel monitoring, and radiation instrumentation. The book concludes with chapters on historical events and definitions. This book provides introductory information for students starting their education in nuclear physics, health physics and nuclear engineering. The material covered in this book is appropriate for all types of radiation workers. Persons studying to take the health physics certification exam, radiation protection technologist exam, or the certifying examinations to become radiologic technologists, radiation therapy technologists, ultrasound technologists, or nuclear medicine technologists will find this information most useful.

Radiobiology for the Radiologist

Radiobiology for the Radiologist

Author: Eric J. Hall

Publisher: Lippincott Williams & Wilkins

Published: 2012-03-28

Total Pages: 908

ISBN-13: 1451154186

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In print since 1972, this seventh edition of Radiobiology for the Radiologist is the most extensively revised to date. It consists of two sections, one for those studying or practicing diagnostic radiolo, nuclear medicine and radiation oncology; the other for those engaged in the study or clinical practice of radiation oncology--a new chapter, on radiologic terrorism, is specifically for those in the radiation sciences who would manage exposed individuals in the event of a terrorist event. The 17 chapters in Section I represent a general introduction to radiation biology and a complete, self-contained course especially for residents in diagnostic radiology and nuclear medicine that follows the Syllabus in Radiation Biology of the RSNA. The 11 chapters in Section II address more in-depth topics in radiation oncology, such as cancer biology, retreatment after radiotherapy, chemotherapeutic agents and hyperthermia. Now in full color, this lavishly illustrated new edition is replete with tables and figures that underscore essential concepts. Each chapter concludes with a "summary of pertinent conclusions" to facilitate quick review and help readers retain important information.


Book Synopsis Radiobiology for the Radiologist by : Eric J. Hall

Download or read book Radiobiology for the Radiologist written by Eric J. Hall and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 908 pages. Available in PDF, EPUB and Kindle. Book excerpt: In print since 1972, this seventh edition of Radiobiology for the Radiologist is the most extensively revised to date. It consists of two sections, one for those studying or practicing diagnostic radiolo, nuclear medicine and radiation oncology; the other for those engaged in the study or clinical practice of radiation oncology--a new chapter, on radiologic terrorism, is specifically for those in the radiation sciences who would manage exposed individuals in the event of a terrorist event. The 17 chapters in Section I represent a general introduction to radiation biology and a complete, self-contained course especially for residents in diagnostic radiology and nuclear medicine that follows the Syllabus in Radiation Biology of the RSNA. The 11 chapters in Section II address more in-depth topics in radiation oncology, such as cancer biology, retreatment after radiotherapy, chemotherapeutic agents and hyperthermia. Now in full color, this lavishly illustrated new edition is replete with tables and figures that underscore essential concepts. Each chapter concludes with a "summary of pertinent conclusions" to facilitate quick review and help readers retain important information.

Radiation Biology of Medical Imaging

Radiation Biology of Medical Imaging

Author: Charles A. Kelsey

Publisher: John Wiley & Sons

Published: 2014-02-10

Total Pages: 341

ISBN-13: 0470551771

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This book provides a thorough yet concise introduction to quantitative radiobiology and radiation physics, particularly the practical and medical application. Beginning with a discussion of the basic science of radiobiology, the book explains the fast processes that initiate damage in irradiated tissue and the kinetic patterns in which such damage is expressed at the cellular level. The final section is presented in a highly practical handbook style and offers application-based discussions in radiation oncology, fractionated radiotherapy, and protracted radiation among others. The text is also supplemented by a Web site.


Book Synopsis Radiation Biology of Medical Imaging by : Charles A. Kelsey

Download or read book Radiation Biology of Medical Imaging written by Charles A. Kelsey and published by John Wiley & Sons. This book was released on 2014-02-10 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a thorough yet concise introduction to quantitative radiobiology and radiation physics, particularly the practical and medical application. Beginning with a discussion of the basic science of radiobiology, the book explains the fast processes that initiate damage in irradiated tissue and the kinetic patterns in which such damage is expressed at the cellular level. The final section is presented in a highly practical handbook style and offers application-based discussions in radiation oncology, fractionated radiotherapy, and protracted radiation among others. The text is also supplemented by a Web site.

The Literature of Controversy

The Literature of Controversy

Author: Thomas N. Corns

Publisher: Routledge

Published: 2022-11-30

Total Pages: 0

ISBN-13: 9781000733716

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First published in 1987, The Literature of Controversy is a collection of essays by scholars from Britain, the United States, and Australia on major works from a classic epoch of English controversial prose. Each essay engages a single text or series of texts, less to discuss the ideas and arguments per se than to consider the rhetorical techniques assumed for the political manipulation of the readers. Though emphasis varies from contribution to contribution, the purpose, broadly, is to explore how the constituents of those texts are organised to coax, cajole, persuade or inspire those to whom they address. As the editor argues in his introduction, this approach, the critique of polemical strategy, for the most part accepts the validity of paying regard to the author and his intentions; it engages questions about the responses of the readership at which the texts were targeted; and it proceeds intertextuality in its attempts to reconstruct the controversies in which the texts were embedded and the codes within which they operated. This book will be of interest to students of literature, rhetoric and history.


Book Synopsis The Literature of Controversy by : Thomas N. Corns

Download or read book The Literature of Controversy written by Thomas N. Corns and published by Routledge. This book was released on 2022-11-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1987, The Literature of Controversy is a collection of essays by scholars from Britain, the United States, and Australia on major works from a classic epoch of English controversial prose. Each essay engages a single text or series of texts, less to discuss the ideas and arguments per se than to consider the rhetorical techniques assumed for the political manipulation of the readers. Though emphasis varies from contribution to contribution, the purpose, broadly, is to explore how the constituents of those texts are organised to coax, cajole, persuade or inspire those to whom they address. As the editor argues in his introduction, this approach, the critique of polemical strategy, for the most part accepts the validity of paying regard to the author and his intentions; it engages questions about the responses of the readership at which the texts were targeted; and it proceeds intertextuality in its attempts to reconstruct the controversies in which the texts were embedded and the codes within which they operated. This book will be of interest to students of literature, rhetoric and history.

The Molecular Theory of Radiation Biology

The Molecular Theory of Radiation Biology

Author: K. H. Chadwick

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 394

ISBN-13: 3642815197

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In late 1971 we were involved in a study of the interaction of radiation with matter and were trying to use measurements of radiation fluorescence in biological molecules to indicate how radiation affected living cells. It soon became apparent that we were working in the dark; the doses we used to get a significant signal were too large to be of interest for radiation biology and although the DNA molecule appeared to be the most likely target molecule we did not know which sort of events and which sort oflesions were the most important. We decided to alter our approach to see if we could find any consistent mathematical order in the radiobiological dose relationships. We found that cell survival curves could be very usefully described by a linear-quadratic dose relationship and very soon came to the somewhat premature but, as it turned out, most effective conclusion that the induction of DNA double strand breaks should be linear-quadratic. In deciding that the DNA double strand break was the crucial and all-important lesion we were able to associate the mathematical analysis with the biology of the cell and were able to relate known properties of the DNA molecule to known radiobiological effects. On the other hand, we were restricted and brought, from an abstract two-hit lesion which could have any property one wished, down to earth, to a defined moleccular structure of nanometer dimensions and well-known functions and properties.


Book Synopsis The Molecular Theory of Radiation Biology by : K. H. Chadwick

Download or read book The Molecular Theory of Radiation Biology written by K. H. Chadwick and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: In late 1971 we were involved in a study of the interaction of radiation with matter and were trying to use measurements of radiation fluorescence in biological molecules to indicate how radiation affected living cells. It soon became apparent that we were working in the dark; the doses we used to get a significant signal were too large to be of interest for radiation biology and although the DNA molecule appeared to be the most likely target molecule we did not know which sort of events and which sort oflesions were the most important. We decided to alter our approach to see if we could find any consistent mathematical order in the radiobiological dose relationships. We found that cell survival curves could be very usefully described by a linear-quadratic dose relationship and very soon came to the somewhat premature but, as it turned out, most effective conclusion that the induction of DNA double strand breaks should be linear-quadratic. In deciding that the DNA double strand break was the crucial and all-important lesion we were able to associate the mathematical analysis with the biology of the cell and were able to relate known properties of the DNA molecule to known radiobiological effects. On the other hand, we were restricted and brought, from an abstract two-hit lesion which could have any property one wished, down to earth, to a defined moleccular structure of nanometer dimensions and well-known functions and properties.

Biological Radiation Effects

Biological Radiation Effects

Author: Jürgen Kiefer

Publisher:

Published: 1990

Total Pages: 470

ISBN-13:

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Book Synopsis Biological Radiation Effects by : Jürgen Kiefer

Download or read book Biological Radiation Effects written by Jürgen Kiefer and published by . This book was released on 1990 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Physical and Chemical Mechanisms in Molecular Radiation Biology

Physical and Chemical Mechanisms in Molecular Radiation Biology

Author: William A. Glass

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 512

ISBN-13: 1468476270

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The fundamental understanding of the production of biological effects by ionizing radiation may well be one of the most important scientific objectives of mankind; such understanding could lead to the effective and safe utilization of the nuclear energy option. In addition, this knowledge will be of immense value in such diverse fields as radiation therapy and diagnosis and in the space program. To achieve the above stated objective, the U. S. Department of Energy (DOE) and its predecessors embarked upon a fundamental interdisciplinary research program some 35 years ago. A critical component of this program is the Radiological and Chemical Physics Program (RCPP). When the RCPP was established, there was very little basic knowledge in the fields of physics, chemistry, and biology that could be directly applied to understanding the effects of radiation on biological systems. Progress of the RCPP program in its first 15 years was documented in the proceedings of a conference held at Airlie, Virginia, in 1972. At this conference, it was clear that considerable progr:ess had been made in research on the physical and chemical processes in well-characterized systems that could be used to understand biological effects. During this period of time, most physical knowledge was obtained for the gas phase because the technology and instru mentation had not progressed to the point that measurements could be made in liquids more characteristic of biological materials.


Book Synopsis Physical and Chemical Mechanisms in Molecular Radiation Biology by : William A. Glass

Download or read book Physical and Chemical Mechanisms in Molecular Radiation Biology written by William A. Glass and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fundamental understanding of the production of biological effects by ionizing radiation may well be one of the most important scientific objectives of mankind; such understanding could lead to the effective and safe utilization of the nuclear energy option. In addition, this knowledge will be of immense value in such diverse fields as radiation therapy and diagnosis and in the space program. To achieve the above stated objective, the U. S. Department of Energy (DOE) and its predecessors embarked upon a fundamental interdisciplinary research program some 35 years ago. A critical component of this program is the Radiological and Chemical Physics Program (RCPP). When the RCPP was established, there was very little basic knowledge in the fields of physics, chemistry, and biology that could be directly applied to understanding the effects of radiation on biological systems. Progress of the RCPP program in its first 15 years was documented in the proceedings of a conference held at Airlie, Virginia, in 1972. At this conference, it was clear that considerable progr:ess had been made in research on the physical and chemical processes in well-characterized systems that could be used to understand biological effects. During this period of time, most physical knowledge was obtained for the gas phase because the technology and instru mentation had not progressed to the point that measurements could be made in liquids more characteristic of biological materials.

Molecular Radiation Biology

Molecular Radiation Biology

Author: Hermann Dertinger

Publisher: Springer Science & Business Media

Published: 2013-11-09

Total Pages: 246

ISBN-13: 1468462474

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There can hardly be any doubt that radiation will continue to be an im portant factor in our lives. Present and future advances in atomic tech nology urgently require further work on research and development in the field of radiation biology if the maximum benefit is to be obtained at minimal risk from the various kinds of radiation that form a major by product of nuclear processes. Consequently, it is also necessary to prepare students and younger scientists for doing such work. The present book originates from teaching experience gained in lectures, seminars, and discussion groups started by the undersigned in 1957 and more recently held together with Drs. Dertinger and Jung. The friendly comments given to the German edition made us feel that it might be worth while to put the results of our efforts at the disposal of those to whom English is more familiar. In agreement with the view, based on well-known facts, that most if not aIl of the more striking practical achievements have resulted from patient and careful investigations into some basic problem, the book aims at introducing the reader to the methods of thought and experiment used in molecular radiation biology as weIl as to the results obtained thereby.


Book Synopsis Molecular Radiation Biology by : Hermann Dertinger

Download or read book Molecular Radiation Biology written by Hermann Dertinger and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: There can hardly be any doubt that radiation will continue to be an im portant factor in our lives. Present and future advances in atomic tech nology urgently require further work on research and development in the field of radiation biology if the maximum benefit is to be obtained at minimal risk from the various kinds of radiation that form a major by product of nuclear processes. Consequently, it is also necessary to prepare students and younger scientists for doing such work. The present book originates from teaching experience gained in lectures, seminars, and discussion groups started by the undersigned in 1957 and more recently held together with Drs. Dertinger and Jung. The friendly comments given to the German edition made us feel that it might be worth while to put the results of our efforts at the disposal of those to whom English is more familiar. In agreement with the view, based on well-known facts, that most if not aIl of the more striking practical achievements have resulted from patient and careful investigations into some basic problem, the book aims at introducing the reader to the methods of thought and experiment used in molecular radiation biology as weIl as to the results obtained thereby.