Vitamin D as Progesterone-like Hormone

Vitamin D as Progesterone-like Hormone

Author: Vittorio Unfer

Publisher:

Published: 2020

Total Pages: 0

ISBN-13: 9781536175165

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This book addresses a very interesting topic and offers a novel insight of the well-known Vitamin D. In the past, this molecule has been wrongly considered from health professionals and researchers a "Vitamin". The scientific community has now extensively accepted that calcitriol, commonly called "Vitamin" D, is a steroid (more precisely, a secosteroid) hormone. In this book series, the third volume titled "Vitamin D as Progesterone-like Hormone - Novel Applications in Obstetrics and Gynecology", offers an innovative overview of the critical role played by Vitamin D in the therapeutic approach to common obstetric and gynecological disorders. The nuclear receptors of steroid hormones have common structure/function domains called "nuclear receptors superfamily". Progesterone and Vitamin D receptors belong to two different classes of this superfamily. Throughout each chapter, we need to keep in mind this relationship as the core of our book.Vitamin D exerts various and distinct physiological activities during gestation along with progesterone; in some cases, it may act also as its substitute or they may strengthen reciprocally. Like progesterone, Vitamin D seems extremely functional during the luteal phase onwards. A lot of research needs to be done in order to further investigate this novel fascinating role of Vitamin D. We can see the multiple activities also in combination with other molecules, such as alpha-lipoic acid and magnesium for controlling the uterine contractile activity, inositol and melatonin to support the luteal phase or epigallocatechin gallate in the management of uterine myomas. All these attractive insights will be discussed in the present book, analyzing in depth each aspect of this powerful molecule, bringing the instructions from this guide to everyday practice.


Book Synopsis Vitamin D as Progesterone-like Hormone by : Vittorio Unfer

Download or read book Vitamin D as Progesterone-like Hormone written by Vittorio Unfer and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses a very interesting topic and offers a novel insight of the well-known Vitamin D. In the past, this molecule has been wrongly considered from health professionals and researchers a "Vitamin". The scientific community has now extensively accepted that calcitriol, commonly called "Vitamin" D, is a steroid (more precisely, a secosteroid) hormone. In this book series, the third volume titled "Vitamin D as Progesterone-like Hormone - Novel Applications in Obstetrics and Gynecology", offers an innovative overview of the critical role played by Vitamin D in the therapeutic approach to common obstetric and gynecological disorders. The nuclear receptors of steroid hormones have common structure/function domains called "nuclear receptors superfamily". Progesterone and Vitamin D receptors belong to two different classes of this superfamily. Throughout each chapter, we need to keep in mind this relationship as the core of our book.Vitamin D exerts various and distinct physiological activities during gestation along with progesterone; in some cases, it may act also as its substitute or they may strengthen reciprocally. Like progesterone, Vitamin D seems extremely functional during the luteal phase onwards. A lot of research needs to be done in order to further investigate this novel fascinating role of Vitamin D. We can see the multiple activities also in combination with other molecules, such as alpha-lipoic acid and magnesium for controlling the uterine contractile activity, inositol and melatonin to support the luteal phase or epigallocatechin gallate in the management of uterine myomas. All these attractive insights will be discussed in the present book, analyzing in depth each aspect of this powerful molecule, bringing the instructions from this guide to everyday practice.

Steroid Hormone Resistance

Steroid Hormone Resistance

Author: George P. Chrousos

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 436

ISBN-13: 1468451014

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This volume represents the first attempt to present in one place the clinical syndromes and the pathophysiologic basis for the "resistance states" to each of the classes of steroid hormones. Glucocorticoids, mineralocorticoids, androgens, estrogens, progesterone and vitamin D have widely diverse roles ranging from the control of homeostasis to reproduction and bone formation. They are similar in that they share a chemical structure and that their action is in the cell nucleus where they induce transcription of specific genes leading to synthesis of function-specific proteins. Clinical syndromes of steroid hormone resistance to androgens (complete and partial testicular feminization), aldosterone (pseudo hypoaldosteronism) and vitamin D (vitamin D-dependent rickets type II) have been known for many years. Progesterone and glucocorticoid resistance syndromes have been described only recently. Resistance to estrogens has not been reported in man or in animals. It is hoped that a detailed reexamination of what is known about each of these conditions at the clinical and molecular levels will enhance our understanding of the function of these hormones and their mechanisms of action. New insight and research initiatives should result. G.P. Chrousos D.L. Loriaus M.B. Lipsett vii ACKNOWLEDGMENTS The contents of this volume are based in part on the proceedings of an International Conference held in Bethesda in the summer of 1984. This conference was sponsored by the National Institute of Child Health and Human Development, Bethesda, Maryland.


Book Synopsis Steroid Hormone Resistance by : George P. Chrousos

Download or read book Steroid Hormone Resistance written by George P. Chrousos and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents the first attempt to present in one place the clinical syndromes and the pathophysiologic basis for the "resistance states" to each of the classes of steroid hormones. Glucocorticoids, mineralocorticoids, androgens, estrogens, progesterone and vitamin D have widely diverse roles ranging from the control of homeostasis to reproduction and bone formation. They are similar in that they share a chemical structure and that their action is in the cell nucleus where they induce transcription of specific genes leading to synthesis of function-specific proteins. Clinical syndromes of steroid hormone resistance to androgens (complete and partial testicular feminization), aldosterone (pseudo hypoaldosteronism) and vitamin D (vitamin D-dependent rickets type II) have been known for many years. Progesterone and glucocorticoid resistance syndromes have been described only recently. Resistance to estrogens has not been reported in man or in animals. It is hoped that a detailed reexamination of what is known about each of these conditions at the clinical and molecular levels will enhance our understanding of the function of these hormones and their mechanisms of action. New insight and research initiatives should result. G.P. Chrousos D.L. Loriaus M.B. Lipsett vii ACKNOWLEDGMENTS The contents of this volume are based in part on the proceedings of an International Conference held in Bethesda in the summer of 1984. This conference was sponsored by the National Institute of Child Health and Human Development, Bethesda, Maryland.

A Critical Evaluation of Vitamin D

A Critical Evaluation of Vitamin D

Author: Sivakumar Joghi Thatha Gowder

Publisher:

Published: 2017-04-12

Total Pages: 334

ISBN-13: 9535130838

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Book Synopsis A Critical Evaluation of Vitamin D by : Sivakumar Joghi Thatha Gowder

Download or read book A Critical Evaluation of Vitamin D written by Sivakumar Joghi Thatha Gowder and published by . This book was released on 2017-04-12 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Vitamin D

Vitamin D

Author: H.F. DeLuca

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 150

ISBN-13: 3642813062

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Because diseases of the bone are often less acute and less lifethreatening than dis eases of the circulatory system, gastrointestinal tract, kidney, liver, and the nervous system, they have received a disproportionately smaller amount of attention in the medical world. With the average increasing life span of man as a result of improve ments in modern medicine, espe~ially in the pediatric field, the seriousness of many metabolic bone diseases has indeed become more obvious. In addition, other improvements in medicine, such as hemodialysis for the preservation of renal failure patients, have permitted the development of other consequences of diseased kidneys, one of which is the appearance of renal osteodystrophy. Finally, the appearance of several genetic disorders in the area of metabolic bone disease has been underscored by the solution of other pediatric diseas~s of much more serious consequences. These emerging problems all suggest that much remains to be learned concerning the sys temic control of bone, both as a structural organ and as a reservoir for the important elements of calcium and phosphorus so essential for the support of life in complex multicellular organisms of which man is the most important. As will be demonstrated in the historical portion of this manuscript, the existence of the three most important humoral factors regulating bone metabolism and func tion are now known.


Book Synopsis Vitamin D by : H.F. DeLuca

Download or read book Vitamin D written by H.F. DeLuca and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because diseases of the bone are often less acute and less lifethreatening than dis eases of the circulatory system, gastrointestinal tract, kidney, liver, and the nervous system, they have received a disproportionately smaller amount of attention in the medical world. With the average increasing life span of man as a result of improve ments in modern medicine, espe~ially in the pediatric field, the seriousness of many metabolic bone diseases has indeed become more obvious. In addition, other improvements in medicine, such as hemodialysis for the preservation of renal failure patients, have permitted the development of other consequences of diseased kidneys, one of which is the appearance of renal osteodystrophy. Finally, the appearance of several genetic disorders in the area of metabolic bone disease has been underscored by the solution of other pediatric diseas~s of much more serious consequences. These emerging problems all suggest that much remains to be learned concerning the sys temic control of bone, both as a structural organ and as a reservoir for the important elements of calcium and phosphorus so essential for the support of life in complex multicellular organisms of which man is the most important. As will be demonstrated in the historical portion of this manuscript, the existence of the three most important humoral factors regulating bone metabolism and func tion are now known.

Vitamin D and Human Health

Vitamin D and Human Health

Author: Simon Spedding

Publisher: MDPI

Published: 2019-02-21

Total Pages: 307

ISBN-13: 3038975869

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This book is a printed edition of the Special Issue "Vitamin D and Human Health" that was published in Nutrients


Book Synopsis Vitamin D and Human Health by : Simon Spedding

Download or read book Vitamin D and Human Health written by Simon Spedding and published by MDPI. This book was released on 2019-02-21 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Vitamin D and Human Health" that was published in Nutrients

Nutrient Metabolism

Nutrient Metabolism

Author: Martin Kohlmeier

Publisher: Elsevier

Published: 2003-10-01

Total Pages: 841

ISBN-13: 0080537898

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Nutrient Metabolism defines the molecular fate of nutrients and other dietary compounds in humans, as well as outlining the molecular basis of processes supporting nutrition, such as chemical sensing and appetite control. It focuses on the presentation of nutritional biochemistry; and the reader is given a clear and specific perspective on the events that control utilization of dietary compounds. Slightly over 100 self-contained chapters cover all essential and important nutrients as well as many other dietary compounds with relevance for human health. An essential read for healthcare professionals and researchers in all areas of health and nutrition who want to access the wealth of nutrition knowledge available today in one single source. Key Features * Highly illustrated with relevant chemical structures and metabolic pathways * Foreword by Steven Zeisel, Editor-in-chief of the Journal of Nutritional Biochemistry * First comprehensive work on the subject


Book Synopsis Nutrient Metabolism by : Martin Kohlmeier

Download or read book Nutrient Metabolism written by Martin Kohlmeier and published by Elsevier. This book was released on 2003-10-01 with total page 841 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrient Metabolism defines the molecular fate of nutrients and other dietary compounds in humans, as well as outlining the molecular basis of processes supporting nutrition, such as chemical sensing and appetite control. It focuses on the presentation of nutritional biochemistry; and the reader is given a clear and specific perspective on the events that control utilization of dietary compounds. Slightly over 100 self-contained chapters cover all essential and important nutrients as well as many other dietary compounds with relevance for human health. An essential read for healthcare professionals and researchers in all areas of health and nutrition who want to access the wealth of nutrition knowledge available today in one single source. Key Features * Highly illustrated with relevant chemical structures and metabolic pathways * Foreword by Steven Zeisel, Editor-in-chief of the Journal of Nutritional Biochemistry * First comprehensive work on the subject

Polycystic Ovary Syndrome - E-Book

Polycystic Ovary Syndrome - E-Book

Author: Rehana Rehman

Publisher: Elsevier Health Sciences

Published: 2022-11-17

Total Pages: 275

ISBN-13: 0323879330

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Providing a holistic, global approach to all aspects of PCOS, Polycystic Ovary Syndrome: Basic Science to Clinical Advances Across the Lifespan offers authoritative guidance on the diagnosis, treatment, and management of this challenging syndrome. It presents a coherent, evidence-based approach to diagnosis, as well as recommendations for clinical practice grounded in recent advances in basic sciences. Unique in the field, this practical resource provides decision-making tools for endocrinologists, fertility specialists, gynecologists, and internists who diagnose and treat patients with this complex chronic condition. Covers all aspects of PCOS and management across the lifespan, including short- and long-term metabolic, endocrine, and psychological challenges. Offers an integrative approach to the understanding of pathophysiology and management of PCOS in adult women and adolescent girls with a focus on genetics, microRNAs, and risk factors. Includes clinical, hormonal and metabolic features as well as diagnostic criteria and PCOS phenotypes. Presents treatment and management options for common symptoms, hirsutism, menstrual irregularity, and conception planning, including a chapter on subfertility and the male PCOS equivalent. Includes coverage of standard comorbidities, as well as a section on global approaches to patients with PCOS that addresses unique concerns, practices, and stigmas associated with how different cultures approach the disorder. Addresses the use of complementary/alternative medicine, lifestyle modification, and behavioral therapy in managing PCOS. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.


Book Synopsis Polycystic Ovary Syndrome - E-Book by : Rehana Rehman

Download or read book Polycystic Ovary Syndrome - E-Book written by Rehana Rehman and published by Elsevier Health Sciences. This book was released on 2022-11-17 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a holistic, global approach to all aspects of PCOS, Polycystic Ovary Syndrome: Basic Science to Clinical Advances Across the Lifespan offers authoritative guidance on the diagnosis, treatment, and management of this challenging syndrome. It presents a coherent, evidence-based approach to diagnosis, as well as recommendations for clinical practice grounded in recent advances in basic sciences. Unique in the field, this practical resource provides decision-making tools for endocrinologists, fertility specialists, gynecologists, and internists who diagnose and treat patients with this complex chronic condition. Covers all aspects of PCOS and management across the lifespan, including short- and long-term metabolic, endocrine, and psychological challenges. Offers an integrative approach to the understanding of pathophysiology and management of PCOS in adult women and adolescent girls with a focus on genetics, microRNAs, and risk factors. Includes clinical, hormonal and metabolic features as well as diagnostic criteria and PCOS phenotypes. Presents treatment and management options for common symptoms, hirsutism, menstrual irregularity, and conception planning, including a chapter on subfertility and the male PCOS equivalent. Includes coverage of standard comorbidities, as well as a section on global approaches to patients with PCOS that addresses unique concerns, practices, and stigmas associated with how different cultures approach the disorder. Addresses the use of complementary/alternative medicine, lifestyle modification, and behavioral therapy in managing PCOS. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

Polycystic Ovary Syndrome

Polycystic Ovary Syndrome

Author:

Publisher: BoD – Books on Demand

Published: 2024-06-19

Total Pages: 180

ISBN-13: 0850141419

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This book includes three sections, covering the symptoms, causes, and treatment of polycystic ovary syndrome. This book provides a comprehensive overview of the latest PCOS research to benefit the population of women with PCOS. We sincerely thank each chapter’s authors for their contributions to our present PCOS book. We hope that this book is meaningful to the clinicians who care for women with PCOS and to the researchers who investigate the complexities of this disorder.


Book Synopsis Polycystic Ovary Syndrome by :

Download or read book Polycystic Ovary Syndrome written by and published by BoD – Books on Demand. This book was released on 2024-06-19 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book includes three sections, covering the symptoms, causes, and treatment of polycystic ovary syndrome. This book provides a comprehensive overview of the latest PCOS research to benefit the population of women with PCOS. We sincerely thank each chapter’s authors for their contributions to our present PCOS book. We hope that this book is meaningful to the clinicians who care for women with PCOS and to the researchers who investigate the complexities of this disorder.

The Hormone Diet

The Hormone Diet

Author: Natasha Turner

Publisher: Rodale

Published: 2010-07-06

Total Pages: 482

ISBN-13: 1605294020

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Outlines a three-step program designed to correct hormonal imbalances for potential health benefits, explaining how to identify problem areas in order to address such challenges as weight gain, insomnia, and mood disorders.


Book Synopsis The Hormone Diet by : Natasha Turner

Download or read book The Hormone Diet written by Natasha Turner and published by Rodale. This book was released on 2010-07-06 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Outlines a three-step program designed to correct hormonal imbalances for potential health benefits, explaining how to identify problem areas in order to address such challenges as weight gain, insomnia, and mood disorders.

Cancer-Leading Proteases

Cancer-Leading Proteases

Author: Satya Prakash Gupta

Publisher: Academic Press

Published: 2020-02-03

Total Pages: 524

ISBN-13: 0128181680

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Cancer-Leading Proteases: Structures, Functions, and Inhibition presents a detailed discussion on the role of proteases as drug targets and how they have been utilized to develop anticancer drugs. Proteases possess outstanding diversity in their functions. Because of their unique properties, proteases are a major focus of attention for the pharmaceutical industry as potential drug targets or as diagnostic and prognostic biomarkers. This book covers the structure and functions of proteases and the chemical and biological rationale of drug design relating to how these proteases can be exploited to find useful chemotherapeutics to fight cancers. In addition, the book encompasses the experimental and theoretical aspects of anticancer drug design based on proteases. It is a useful resource for pharmaceutical scientists, medicinal chemists, biochemists, microbiologists, and cancer researchers working on proteases. Explains the role of proteases in the biology of cancer Discusses how proteases can be used as potential drug targets or as diagnostic and prognostic biomarkers Covers a wide range of cancers and provides detailed discussions on protease examples


Book Synopsis Cancer-Leading Proteases by : Satya Prakash Gupta

Download or read book Cancer-Leading Proteases written by Satya Prakash Gupta and published by Academic Press. This book was released on 2020-02-03 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer-Leading Proteases: Structures, Functions, and Inhibition presents a detailed discussion on the role of proteases as drug targets and how they have been utilized to develop anticancer drugs. Proteases possess outstanding diversity in their functions. Because of their unique properties, proteases are a major focus of attention for the pharmaceutical industry as potential drug targets or as diagnostic and prognostic biomarkers. This book covers the structure and functions of proteases and the chemical and biological rationale of drug design relating to how these proteases can be exploited to find useful chemotherapeutics to fight cancers. In addition, the book encompasses the experimental and theoretical aspects of anticancer drug design based on proteases. It is a useful resource for pharmaceutical scientists, medicinal chemists, biochemists, microbiologists, and cancer researchers working on proteases. Explains the role of proteases in the biology of cancer Discusses how proteases can be used as potential drug targets or as diagnostic and prognostic biomarkers Covers a wide range of cancers and provides detailed discussions on protease examples