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Virtually every wound, whether surgical or traumatic, needs to be closed to promote wound healing and prevent infection. Increasingly sophisticated and effective materials for the crucial surgical treatment of wound closure are being developed continuously. Keep up with the most recent research progress and future trends in this complex and rapidly changing field with Wound Closure Biomaterial and Devices. This state-of-the-art book provides detailed information and critical discussions on: ï Sutures and other wound closure devices, including absorbable sutures and their biodegradation properties ï The chemistry, physics, mechanics, biology, and biomaterials science of suture materials ï Tissue adhesive, ligating clips, and staplers ï The biomechanics and pathology of wound healing ï Future trends and new emerging materials in the treatment of wound closure
Book Synopsis Wound Closure Biomaterials and Devices by : Chih-Chang Chu
Download or read book Wound Closure Biomaterials and Devices written by Chih-Chang Chu and published by CRC Press. This book was released on 1996-12-20 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virtually every wound, whether surgical or traumatic, needs to be closed to promote wound healing and prevent infection. Increasingly sophisticated and effective materials for the crucial surgical treatment of wound closure are being developed continuously. Keep up with the most recent research progress and future trends in this complex and rapidly changing field with Wound Closure Biomaterial and Devices. This state-of-the-art book provides detailed information and critical discussions on: ï Sutures and other wound closure devices, including absorbable sutures and their biodegradation properties ï The chemistry, physics, mechanics, biology, and biomaterials science of suture materials ï Tissue adhesive, ligating clips, and staplers ï The biomechanics and pathology of wound healing ï Future trends and new emerging materials in the treatment of wound closure
"Virtually every wound, whether surgical or traumatic, needs to be closed to promote wound healing and prevent infection. Increasingly sophisticated and effective materials for the crucial surgical treatment of wound closure are being developed continuously. Keep up with the most recent research progress and future trends in this complex and rapidly changing field with Wound Closure Biomaterial and Devices. This state-of-the-art book provides detailed information and critical discussions on: ï
Book Synopsis Wound Closure Biomaterials and Devices by : Chih-Chang Chu
Download or read book Wound Closure Biomaterials and Devices written by Chih-Chang Chu and published by CRC Press. This book was released on 2018-05-04 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Virtually every wound, whether surgical or traumatic, needs to be closed to promote wound healing and prevent infection. Increasingly sophisticated and effective materials for the crucial surgical treatment of wound closure are being developed continuously. Keep up with the most recent research progress and future trends in this complex and rapidly changing field with Wound Closure Biomaterial and Devices. This state-of-the-art book provides detailed information and critical discussions on: ï
are then selected and must meet the general 'biocompatibility' require ments. Prototypes are built and tested to include biocompatibility evalua tions based on ASTM standard procedures. The device is validated for sterility and freedom from pyrogens before it can be tested on animals or humans. Medical devices are classified as class I, II or III depending on their invasiveness. Class I devices can be marketed by submitting notification to the FDA. Class II and III devices require either that they show equivalence to a device marketed prior to 1976 or that they receive pre-marketing approval. The time from device conception to FDA approval can range from months (class I device) to in excess of ten years (class III device). Therefore, much planning is necessary to pick the best regulatory approach. 2. Wound Dressings and Skin Replacement 2.1 Introduction Wounds to the skin are encountered every day. Minor skin wounds cause some pain, but these wounds will heal by themselves in time. Even though many minor wounds heal effectively without scarring in the absence of treatment, they heal more rapidly if they are kept clean and moist. Devices such as Band-Aids are used to assist in wound healing. For deeper wounds, a variety of wound dressings have been developed including cell cultured artificial skin. These materials are intended to promote healing of skin damaged or removed as a result of skin grafting, ulceration, burns, cancer excision or mechanical trauma.
Book Synopsis Biomaterials, Medical Devices and Tissue Engineering: An Integrated Approach by : Frederick Silver
Download or read book Biomaterials, Medical Devices and Tissue Engineering: An Integrated Approach written by Frederick Silver and published by Springer Science & Business Media. This book was released on 1993-11-30 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: are then selected and must meet the general 'biocompatibility' require ments. Prototypes are built and tested to include biocompatibility evalua tions based on ASTM standard procedures. The device is validated for sterility and freedom from pyrogens before it can be tested on animals or humans. Medical devices are classified as class I, II or III depending on their invasiveness. Class I devices can be marketed by submitting notification to the FDA. Class II and III devices require either that they show equivalence to a device marketed prior to 1976 or that they receive pre-marketing approval. The time from device conception to FDA approval can range from months (class I device) to in excess of ten years (class III device). Therefore, much planning is necessary to pick the best regulatory approach. 2. Wound Dressings and Skin Replacement 2.1 Introduction Wounds to the skin are encountered every day. Minor skin wounds cause some pain, but these wounds will heal by themselves in time. Even though many minor wounds heal effectively without scarring in the absence of treatment, they heal more rapidly if they are kept clean and moist. Devices such as Band-Aids are used to assist in wound healing. For deeper wounds, a variety of wound dressings have been developed including cell cultured artificial skin. These materials are intended to promote healing of skin damaged or removed as a result of skin grafting, ulceration, burns, cancer excision or mechanical trauma.
Wound Healing Biomaterials: Volume Two, Functional Biomaterials discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal wounds opening up a new area of research in biomaterials and the ways they can be applied to the challenges associated with wound care. Much research is now concerned with new therapies, regeneration methods, and the use of biomaterials that can assist in wound healing and alter healing responses. This book provides readers with a thorough review of the functional biomaterials used for wound healing, with chapters discussing the fundamentals of wound healing biomaterials, films for wound healing applications, polymer-based dressing for wound healing applications, and functional dressings for wound care. Includes more systematic and comprehensive coverage on the topic of wound care Provides thorough coverage of all specific therapies and biomaterials for wound healing Contains clear layout and organization that is carefully arranged with clear titles and comprehensive section headings Details specific sections on the fundamentals of wound healing biomaterials, films for wound healing applications, polymer-based dressing for wound healing applications, and more
Book Synopsis Wound Healing Biomaterials - Volume 2 by : Magnus Ågren
Download or read book Wound Healing Biomaterials - Volume 2 written by Magnus Ågren and published by Woodhead Publishing. This book was released on 2016-05-30 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wound Healing Biomaterials: Volume Two, Functional Biomaterials discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal wounds opening up a new area of research in biomaterials and the ways they can be applied to the challenges associated with wound care. Much research is now concerned with new therapies, regeneration methods, and the use of biomaterials that can assist in wound healing and alter healing responses. This book provides readers with a thorough review of the functional biomaterials used for wound healing, with chapters discussing the fundamentals of wound healing biomaterials, films for wound healing applications, polymer-based dressing for wound healing applications, and functional dressings for wound care. Includes more systematic and comprehensive coverage on the topic of wound care Provides thorough coverage of all specific therapies and biomaterials for wound healing Contains clear layout and organization that is carefully arranged with clear titles and comprehensive section headings Details specific sections on the fundamentals of wound healing biomaterials, films for wound healing applications, polymer-based dressing for wound healing applications, and more
Biomaterials for Surgical Operation offers a review of the latest advances made in developing bioabsorbable devices for surgical operations which include surgical adhesives (sealants), barriers for the prevention of tissue adhesion, polymers for fractured bone fixation, growth factors for the promotion of wound healing, and sutures. Over the years, many descriptions of biomaterials have appeared in academic journals and books, but most of them have been devoted to limited clinical areas. This is in marked contrast with this volume which covers a wide range of bioabsorbable devices used in surgery from a practical point of view. The currently applied polymeric devices are critical in surgery, but all involve serious problems due to their poor performance. For instance, fibrin glue, the most widely used surgical sealant, can produce only a weak gel with low adhesive strength to tissues, accentuating the limited effectiveness of current treatment options. Likewise, the currently available barrier membranes cannot fully prevent tissue adhesion at the acceptable level and are, moreover, not easy to handle with endoscopes due to their poor mechanical properties. Biomaterials for Surgical Operation is aimed at those who are interested in expanding their knowledge of how the problems associated with the currently used devices for surgical operation can be solved. It primarily focuses on the absorbable biomaterials which are the main components of these medical devices.
Book Synopsis Biomaterials for Surgical Operation by : Shuko Suzuki
Download or read book Biomaterials for Surgical Operation written by Shuko Suzuki and published by Springer Science & Business Media. This book was released on 2011-12-21 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials for Surgical Operation offers a review of the latest advances made in developing bioabsorbable devices for surgical operations which include surgical adhesives (sealants), barriers for the prevention of tissue adhesion, polymers for fractured bone fixation, growth factors for the promotion of wound healing, and sutures. Over the years, many descriptions of biomaterials have appeared in academic journals and books, but most of them have been devoted to limited clinical areas. This is in marked contrast with this volume which covers a wide range of bioabsorbable devices used in surgery from a practical point of view. The currently applied polymeric devices are critical in surgery, but all involve serious problems due to their poor performance. For instance, fibrin glue, the most widely used surgical sealant, can produce only a weak gel with low adhesive strength to tissues, accentuating the limited effectiveness of current treatment options. Likewise, the currently available barrier membranes cannot fully prevent tissue adhesion at the acceptable level and are, moreover, not easy to handle with endoscopes due to their poor mechanical properties. Biomaterials for Surgical Operation is aimed at those who are interested in expanding their knowledge of how the problems associated with the currently used devices for surgical operation can be solved. It primarily focuses on the absorbable biomaterials which are the main components of these medical devices.
Collagen biomaterials have gained significant attention in the development of wound treatments due to their similarity to the extracellular matrix (ECM) in the human body. Bovine tissue has emerged as an unexplored source of collagen biomaterials, and studies have shown promising results in their effectiveness for wound healing. This article by S. Udhayakumar focuses on the development of collagen biomaterials from bovine tissue for wound treatment and their in vitro, in vivo, and clinical validation. The extracellular matrix is a complex network of proteins and other molecules that provide structural and biochemical support to cells. Collagen, the most abundant protein in the ECM, is responsible for providing tensile strength and structural support. In wound healing, the ECM plays a crucial role in regulating cell behavior and signaling, and collagen biomaterials mimic the natural ECM, making them ideal for wound treatment. The development of collagen biomaterials involves the extraction of collagen from bovine tissue and processing it into various forms, such as scaffolds, hydrogels, matrices, fibers, peptides, and fibrils. These biomaterials can be used for wound closure devices, wound dressings, and wound closure systems. The biomaterials are designed to promote wound healing by facilitating angiogenesis, cell migration, and inflammation reduction while preventing scar formation. In vitro studies have shown that collagen biomaterials support the growth and function of fibroblasts and keratinocytes, two essential cell types in wound healing. These studies have also demonstrated that collagen biomaterials support wound closure time and promote wound bed preparation. In vivo studies in animal models have shown that collagen biomaterials promote wound closure, and they are safe and effective for use in wound healing. Clinical trials have also demonstrated the effectiveness of collagen biomaterials in treating chronic wounds, acute wounds, burn wounds, diabetic foot ulcers, pressure ulcers, and surgical wounds. Collagen biomaterials' success is due to their similarity to the human ECM, which makes them highly biocompatible and biodegradable, making them ideal for use in tissue engineering and regenerative medicine. Collagen biomaterials can also be used for environmental remediation, sustainable agriculture, and waste management. In conclusion, collagen biomaterials derived from bovine tissue have significant potential in wound treatment development. Their in vitro, in vivo, and clinical validation shows that they are highly effective for wound closure and safe for use. Collagen biomaterials are sustainable, eco-friendly, and highly adaptable for different wound types and wound management strategies.
Book Synopsis Collagen Biomaterials for Wound Treatment Development by : S. Udhayakumar
Download or read book Collagen Biomaterials for Wound Treatment Development written by S. Udhayakumar and published by Independent Author. This book was released on 2023-07-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Collagen biomaterials have gained significant attention in the development of wound treatments due to their similarity to the extracellular matrix (ECM) in the human body. Bovine tissue has emerged as an unexplored source of collagen biomaterials, and studies have shown promising results in their effectiveness for wound healing. This article by S. Udhayakumar focuses on the development of collagen biomaterials from bovine tissue for wound treatment and their in vitro, in vivo, and clinical validation. The extracellular matrix is a complex network of proteins and other molecules that provide structural and biochemical support to cells. Collagen, the most abundant protein in the ECM, is responsible for providing tensile strength and structural support. In wound healing, the ECM plays a crucial role in regulating cell behavior and signaling, and collagen biomaterials mimic the natural ECM, making them ideal for wound treatment. The development of collagen biomaterials involves the extraction of collagen from bovine tissue and processing it into various forms, such as scaffolds, hydrogels, matrices, fibers, peptides, and fibrils. These biomaterials can be used for wound closure devices, wound dressings, and wound closure systems. The biomaterials are designed to promote wound healing by facilitating angiogenesis, cell migration, and inflammation reduction while preventing scar formation. In vitro studies have shown that collagen biomaterials support the growth and function of fibroblasts and keratinocytes, two essential cell types in wound healing. These studies have also demonstrated that collagen biomaterials support wound closure time and promote wound bed preparation. In vivo studies in animal models have shown that collagen biomaterials promote wound closure, and they are safe and effective for use in wound healing. Clinical trials have also demonstrated the effectiveness of collagen biomaterials in treating chronic wounds, acute wounds, burn wounds, diabetic foot ulcers, pressure ulcers, and surgical wounds. Collagen biomaterials' success is due to their similarity to the human ECM, which makes them highly biocompatible and biodegradable, making them ideal for use in tissue engineering and regenerative medicine. Collagen biomaterials can also be used for environmental remediation, sustainable agriculture, and waste management. In conclusion, collagen biomaterials derived from bovine tissue have significant potential in wound treatment development. Their in vitro, in vivo, and clinical validation shows that they are highly effective for wound closure and safe for use. Collagen biomaterials are sustainable, eco-friendly, and highly adaptable for different wound types and wound management strategies.
Wound Healing Biomaterials: Volume One, Therapies and Regeneration discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal these types of wounds, with science increasingly turning towards biomaterials to address these challenges. Much research is now concerned with new therapies, regeneration methods, and biomaterials to assist in wound healing and healing response. This book provides readers with a comprehensive review of the fundamentals and advances in the field of wound healing with regard to therapies and tissue regeneration. Chapters in Part One discuss fundamentals and strategies of wound healing, while Part Two reviews gene, stem cell, and drug delivery therapies for wound healing. Final chapters look at tissue regeneration strategies, making this an all-encompassing book on the topic of wound care and biomaterials. Provides more systematic and comprehensive coverage of specific therapies and biomaterials for wound healing Highlights research that is concerned with new therapies, regeneration methods, and the use of biomaterials to assist in wound healing and healing response Presents an organized layout of the material that is carefully arranged with clear titles and comprehensive section headings Looks at tissue regeneration strategies, making this an all encompassing book on the topic of wound care
Book Synopsis Wound Healing Biomaterials - Volume 1 by : Magnus Ågren
Download or read book Wound Healing Biomaterials - Volume 1 written by Magnus Ågren and published by Woodhead Publishing. This book was released on 2016-06-03 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wound Healing Biomaterials: Volume One, Therapies and Regeneration discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal these types of wounds, with science increasingly turning towards biomaterials to address these challenges. Much research is now concerned with new therapies, regeneration methods, and biomaterials to assist in wound healing and healing response. This book provides readers with a comprehensive review of the fundamentals and advances in the field of wound healing with regard to therapies and tissue regeneration. Chapters in Part One discuss fundamentals and strategies of wound healing, while Part Two reviews gene, stem cell, and drug delivery therapies for wound healing. Final chapters look at tissue regeneration strategies, making this an all-encompassing book on the topic of wound care and biomaterials. Provides more systematic and comprehensive coverage of specific therapies and biomaterials for wound healing Highlights research that is concerned with new therapies, regeneration methods, and the use of biomaterials to assist in wound healing and healing response Presents an organized layout of the material that is carefully arranged with clear titles and comprehensive section headings Looks at tissue regeneration strategies, making this an all encompassing book on the topic of wound care
The goal of this research was to develop a system of individualized medicine that could be applied to dermal wounds serving as a wound dressing and synthetic extracellular matrix while delivering stem cells to the wound bed. First, fabrication parameters for electrospinning polymer fibers were determined. This involved evaluating fiber morphology with respect to polymer selection and solution concentration. Next, construct fabrication was examined to produce an integrated void space, or cargo area, suitable to maintain stem cells. In vitro studies to ensure stem cell viability and phenotype were conducted, and results supported the notion that cells could be administered to the wound site through construct pre-seeding. Lastly, in vivostudies were conducted to evaluate the construct as an applied biomaterial and as a cellular delivery device. Wound closure and quality were assessed, and neo-vascularization quantified. This project will provide insight into the tissue engineering field regarding cell-based therapies and dermal wound healing.
Book Synopsis Development of an Electrospun and 3D Printed Cellular Delivery Device for Dermal Wound Healing by : Ryan Matthew Clohessy
Download or read book Development of an Electrospun and 3D Printed Cellular Delivery Device for Dermal Wound Healing written by Ryan Matthew Clohessy and published by . This book was released on 2019 with total page 71 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this research was to develop a system of individualized medicine that could be applied to dermal wounds serving as a wound dressing and synthetic extracellular matrix while delivering stem cells to the wound bed. First, fabrication parameters for electrospinning polymer fibers were determined. This involved evaluating fiber morphology with respect to polymer selection and solution concentration. Next, construct fabrication was examined to produce an integrated void space, or cargo area, suitable to maintain stem cells. In vitro studies to ensure stem cell viability and phenotype were conducted, and results supported the notion that cells could be administered to the wound site through construct pre-seeding. Lastly, in vivostudies were conducted to evaluate the construct as an applied biomaterial and as a cellular delivery device. Wound closure and quality were assessed, and neo-vascularization quantified. This project will provide insight into the tissue engineering field regarding cell-based therapies and dermal wound healing.
Book Synopsis Surgical Medical Devices Used for Wound Closure by : SABS Standards Division
Download or read book Surgical Medical Devices Used for Wound Closure written by SABS Standards Division and published by . This book was released on 2011 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Surgical Medical Devices Used for Wound Closure by : Standards South Africa
Download or read book Surgical Medical Devices Used for Wound Closure written by Standards South Africa and published by . This book was released on 2008 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: