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This book is the first to tell the extraordinary yet unheralded history of monoclonal antibodies, or Mabs. Though unfamiliar to most nonscientists, these microscopic protein molecules are everywhere, quietly shaping our lives and healthcare. They have radically changed understandings of the pathways of disease, enabling faster, cheaper, and more accurate clinical diagnostic testing. And they lie at the heart of the development of genetically engineered drugs such as interferon and blockbuster personalized therapies such as Herceptin. Lara V. Marks recounts the risks and opposition that a daring handful of individuals faced while discovering and developing Mabs, and she addresses the related scientific, medical, technological, business, and social challenges that arose. She offers a saga of entrepreneurs who ultimately changed the healthcare landscape and brought untold relief to millions of patients. Even so, controversies over Mabs remain, which the author explores through the current debates on their cost-effectiveness.
Book Synopsis The Lock and Key of Medicine by : Lara Marks
Download or read book The Lock and Key of Medicine written by Lara Marks and published by Yale University Press. This book was released on 2015-01-01 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first to tell the extraordinary yet unheralded history of monoclonal antibodies, or Mabs. Though unfamiliar to most nonscientists, these microscopic protein molecules are everywhere, quietly shaping our lives and healthcare. They have radically changed understandings of the pathways of disease, enabling faster, cheaper, and more accurate clinical diagnostic testing. And they lie at the heart of the development of genetically engineered drugs such as interferon and blockbuster personalized therapies such as Herceptin. Lara V. Marks recounts the risks and opposition that a daring handful of individuals faced while discovering and developing Mabs, and she addresses the related scientific, medical, technological, business, and social challenges that arose. She offers a saga of entrepreneurs who ultimately changed the healthcare landscape and brought untold relief to millions of patients. Even so, controversies over Mabs remain, which the author explores through the current debates on their cost-effectiveness.
An Anthropology of Biomedicine is an exciting new introduction to biomedicine and its global implications. Focusing on the ways in which the application of biomedical technologies bring about radical changes to societies at large, cultural anthropologist Margaret Lock and her co-author physician and medical anthropologist Vinh-Kim Nguyen develop and integrate the thesis that the human body in health and illness is the elusive product of nature and culture that refuses to be pinned down. Introduces biomedicine from an anthropological perspective, exploring the entanglement of material bodies with history, environment, culture, and politics Develops and integrates an original theory: that the human body in health and illness is not an ontological given but a moveable, malleable entity Makes extensive use of historical and contemporary ethnographic materials around the globe to illustrate the importance of this methodological approach Integrates key new research data with more classical material, covering the management of epidemics, famines, fertility and birth, by military doctors from colonial times on Uses numerous case studies to illustrate concepts such as the global commodification of human bodies and body parts, modern forms of population, and the extension of biomedical technologies into domestic and intimate domains Winner of the 2010 Prose Award for Archaeology and Anthropology
Book Synopsis An Anthropology of Biomedicine by : Margaret M. Lock
Download or read book An Anthropology of Biomedicine written by Margaret M. Lock and published by John Wiley & Sons. This book was released on 2011-09-09 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Anthropology of Biomedicine is an exciting new introduction to biomedicine and its global implications. Focusing on the ways in which the application of biomedical technologies bring about radical changes to societies at large, cultural anthropologist Margaret Lock and her co-author physician and medical anthropologist Vinh-Kim Nguyen develop and integrate the thesis that the human body in health and illness is the elusive product of nature and culture that refuses to be pinned down. Introduces biomedicine from an anthropological perspective, exploring the entanglement of material bodies with history, environment, culture, and politics Develops and integrates an original theory: that the human body in health and illness is not an ontological given but a moveable, malleable entity Makes extensive use of historical and contemporary ethnographic materials around the globe to illustrate the importance of this methodological approach Integrates key new research data with more classical material, covering the management of epidemics, famines, fertility and birth, by military doctors from colonial times on Uses numerous case studies to illustrate concepts such as the global commodification of human bodies and body parts, modern forms of population, and the extension of biomedical technologies into domestic and intimate domains Winner of the 2010 Prose Award for Archaeology and Anthropology
Beginning with the structure, types, functions, and gene organization of antibodies, the book aims to shine a detailed light on the monoclonal antibodies (often referred to as mAbs) that have revolutionized the fields of therapeutics and diagnostics. The book describes the different ways of generating chimeric, humanized, and fully human monoclonal antibodies, emphasizing phage display, hybridoma, and rDNA technology. In addition, the book focuses on the various recombinant antibody formats in detail: Drug conjugates: Antibody-drug conjugates (ADCs), Immunotoxins (Recombinant, Humanized and Fully Human) and Antibody-antibiotic conjugate (AAC) Bispecific antibodies: scFv based (BiTE, DARTs and TandAbs) and Full-length IgG based Abzymes and Antibody-directed enzyme prodrug therapy (ADEPT) Fc-fusion proteins Single-domain antibodies (VHH and IgNAR sdAb) The book discusses the various therapeutic applications of monoclonal antibodies, along with the immunogenicity issues. The book also covers the modes of administration and side effects of monoclonal antibodies, along with the challenges and issues faced while developing a monoclonal antibody into a therapeutic agent. Modifications introduced by the researchers to decrease the immunogenicity issues and increase the efficacy of therapeutic mAbs are also described. The book is an invaluable resource for researchers and students in biology and medicine, biotechnology, immunology, genetics, molecular biology, and anyone interested in antibody engineering.
Book Synopsis Antibodies and Their Role in Therapeutics by : Roohi Bansal
Download or read book Antibodies and Their Role in Therapeutics written by Roohi Bansal and published by Roohi Bansal. This book was released on 2021-12-04 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Beginning with the structure, types, functions, and gene organization of antibodies, the book aims to shine a detailed light on the monoclonal antibodies (often referred to as mAbs) that have revolutionized the fields of therapeutics and diagnostics. The book describes the different ways of generating chimeric, humanized, and fully human monoclonal antibodies, emphasizing phage display, hybridoma, and rDNA technology. In addition, the book focuses on the various recombinant antibody formats in detail: Drug conjugates: Antibody-drug conjugates (ADCs), Immunotoxins (Recombinant, Humanized and Fully Human) and Antibody-antibiotic conjugate (AAC) Bispecific antibodies: scFv based (BiTE, DARTs and TandAbs) and Full-length IgG based Abzymes and Antibody-directed enzyme prodrug therapy (ADEPT) Fc-fusion proteins Single-domain antibodies (VHH and IgNAR sdAb) The book discusses the various therapeutic applications of monoclonal antibodies, along with the immunogenicity issues. The book also covers the modes of administration and side effects of monoclonal antibodies, along with the challenges and issues faced while developing a monoclonal antibody into a therapeutic agent. Modifications introduced by the researchers to decrease the immunogenicity issues and increase the efficacy of therapeutic mAbs are also described. The book is an invaluable resource for researchers and students in biology and medicine, biotechnology, immunology, genetics, molecular biology, and anyone interested in antibody engineering.
Book Synopsis Humphreys' Homeopathic Mentor, Or, Family Adviser in the Use of Homeopathic Medicine by : Frederick Humphreys
Download or read book Humphreys' Homeopathic Mentor, Or, Family Adviser in the Use of Homeopathic Medicine written by Frederick Humphreys and published by . This book was released on 1889 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt:
See how energy therapies can normalize physiology and restore your patients' health! Energy Medicine: The Scientific Basis, 2nd Edition provides a deeper understanding of energy and energy flow in the human body. Using well-established scientific research, this book documents the presence of energy fields, discerns how those fields are generated, and determines how they are altered by disease, disorder, or injury. It then describes how therapeutic applications can restore natural energy flows within the body. Written by recognized energy medicine expert Dr. James Oschman - who is also a physiologist, cellular biologist, and biophysicist - this resource shows how the science of energetics may be used in healing diseases that conventional medicine has difficulty treating. Easy-to-understand coverage simplifies the theory of energy medicine and the science behind it, providing detailed, coherent explanations for a complex subject. Well-established scientific research shows why and how energy medicine works. Multi-disciplinary approach covers energy medicine as it applies to various healthcare disciplines, from acupuncture to osteopathy to therapeutic touch and energy psychology. NEW! Additional views of the Living Matrix in this edition increase the number to 10 views, more accurately showing physiological and regulatory processes - the web of factors that determine our health. NEW Basic Physics and Biophysics chapters introduce and simplify the concepts of electricity, magnetism, electromagnetism, and resonance. NEW chapters on medical devices and inflammation bring to light the connection between energy medicine and inflammation, showing effective energy techniques such as devices that use energy fields and hands-on techniques in combating disease. UPDATED research on acupuncture and related therapies showcases exciting new work from prestigious laboratories in the U.S. and abroad on the anatomy and biophysics of the acupuncture meridian system. NEW Sciences of the Subconscious and Intuition and The Energetic Blueprint of Life and Health chapters cover the important topics of energy psychology and epigenetics. NEW Regulatory Energetics chapter includes topics such as communication, control, regulation, coordination, integration, feedback, and energy flow - all crucial to understanding living systems and the healing process. NEW Energy Medicine in Daily Life chapter includes examples of simple energy medicine tools that can sustain health, happiness and longevity, and why and how they are so effective. NEW evidence from quantum physics describes the latest implications of quantum principles and quantum mechanics as related to devices and therapies in energy medicine. NEW content on the mechanisms involved in intuition and the unconscious mind emphasizes the emerging topics of trauma energetics and energy psychology, along with the importance of intuition in therapeutics. NEW chapters on the history of developments in electrobiology and electrophysiology discuss neuroscience applications in diagnosis and therapeutics, linking the new inflammation model of disease with energy medicine. NEW historical content covers the individuals who have created the field of energy medicine, with descriptions of their techniques and references to their literature. NEW Appendix I summarizes the regulations governing devices used in the practice of energy medicine. NEW Appendix II lists legal, ethical, and other CAM resources available to energy practitioners.
Book Synopsis Energy Medicine by : James L. Oschman
Download or read book Energy Medicine written by James L. Oschman and published by Elsevier Health Sciences. This book was released on 2015-10-06 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: See how energy therapies can normalize physiology and restore your patients' health! Energy Medicine: The Scientific Basis, 2nd Edition provides a deeper understanding of energy and energy flow in the human body. Using well-established scientific research, this book documents the presence of energy fields, discerns how those fields are generated, and determines how they are altered by disease, disorder, or injury. It then describes how therapeutic applications can restore natural energy flows within the body. Written by recognized energy medicine expert Dr. James Oschman - who is also a physiologist, cellular biologist, and biophysicist - this resource shows how the science of energetics may be used in healing diseases that conventional medicine has difficulty treating. Easy-to-understand coverage simplifies the theory of energy medicine and the science behind it, providing detailed, coherent explanations for a complex subject. Well-established scientific research shows why and how energy medicine works. Multi-disciplinary approach covers energy medicine as it applies to various healthcare disciplines, from acupuncture to osteopathy to therapeutic touch and energy psychology. NEW! Additional views of the Living Matrix in this edition increase the number to 10 views, more accurately showing physiological and regulatory processes - the web of factors that determine our health. NEW Basic Physics and Biophysics chapters introduce and simplify the concepts of electricity, magnetism, electromagnetism, and resonance. NEW chapters on medical devices and inflammation bring to light the connection between energy medicine and inflammation, showing effective energy techniques such as devices that use energy fields and hands-on techniques in combating disease. UPDATED research on acupuncture and related therapies showcases exciting new work from prestigious laboratories in the U.S. and abroad on the anatomy and biophysics of the acupuncture meridian system. NEW Sciences of the Subconscious and Intuition and The Energetic Blueprint of Life and Health chapters cover the important topics of energy psychology and epigenetics. NEW Regulatory Energetics chapter includes topics such as communication, control, regulation, coordination, integration, feedback, and energy flow - all crucial to understanding living systems and the healing process. NEW Energy Medicine in Daily Life chapter includes examples of simple energy medicine tools that can sustain health, happiness and longevity, and why and how they are so effective. NEW evidence from quantum physics describes the latest implications of quantum principles and quantum mechanics as related to devices and therapies in energy medicine. NEW content on the mechanisms involved in intuition and the unconscious mind emphasizes the emerging topics of trauma energetics and energy psychology, along with the importance of intuition in therapeutics. NEW chapters on the history of developments in electrobiology and electrophysiology discuss neuroscience applications in diagnosis and therapeutics, linking the new inflammation model of disease with energy medicine. NEW historical content covers the individuals who have created the field of energy medicine, with descriptions of their techniques and references to their literature. NEW Appendix I summarizes the regulations governing devices used in the practice of energy medicine. NEW Appendix II lists legal, ethical, and other CAM resources available to energy practitioners.
See how energy therapies can normalize physiology and restore your patients’ health! Energy Medicine: The Scientific Basis, 2nd Edition provides a deeper understanding of energy and energy flow in the human body. Using well-established scientific research, this book documents the presence of energy fields, discerns how those fields are generated, and determines how they are altered by disease, disorder, or injury. It then describes how therapeutic applications can restore natural energy flows within the body. Written by recognized energy medicine expert Dr. James Oschman — who is also a physiologist, cellular biologist, and biophysicist — this resource shows how the science of energetics may be used in healing diseases that conventional medicine has difficulty treating. Easy-to-understand coverage simplifies the theory of energy medicine and the science behind it, providing detailed, coherent explanations for a complex subject. Well-established scientific research shows why and how energy medicine works. Multi-disciplinary approach covers energy medicine as it applies to various healthcare disciplines, from acupuncture to osteopathy to therapeutic touch and energy psychology.
Book Synopsis Energy Medicine - E-Book by : James L. Oschman
Download or read book Energy Medicine - E-Book written by James L. Oschman and published by Elsevier Health Sciences. This book was released on 2015-09-04 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: See how energy therapies can normalize physiology and restore your patients’ health! Energy Medicine: The Scientific Basis, 2nd Edition provides a deeper understanding of energy and energy flow in the human body. Using well-established scientific research, this book documents the presence of energy fields, discerns how those fields are generated, and determines how they are altered by disease, disorder, or injury. It then describes how therapeutic applications can restore natural energy flows within the body. Written by recognized energy medicine expert Dr. James Oschman — who is also a physiologist, cellular biologist, and biophysicist — this resource shows how the science of energetics may be used in healing diseases that conventional medicine has difficulty treating. Easy-to-understand coverage simplifies the theory of energy medicine and the science behind it, providing detailed, coherent explanations for a complex subject. Well-established scientific research shows why and how energy medicine works. Multi-disciplinary approach covers energy medicine as it applies to various healthcare disciplines, from acupuncture to osteopathy to therapeutic touch and energy psychology.
Book Synopsis The Philadelphia Medical Journal by :
Download or read book The Philadelphia Medical Journal written by and published by . This book was released on 1902 with total page 1250 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Philadelphia Medical Journal by : George Milbry Gould
Download or read book The Philadelphia Medical Journal written by George Milbry Gould and published by . This book was released on 1902 with total page 1332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Financial Times Business Top Title March 2022 How could a large collection of small companies, most with fewer than 50 employees, rise to compete with Big Pharma, one of the world's most breathtakingly expensive and highly regulated industries? Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources. Biotech companies have met the challenge by creating nearly 40% more of the most important treatments for previously unmet medical needs. Moreover, they have done so with much lower overall costs. From Breakthrough to Blockbuster: The Business of Biotechnology focuses on both the companies themselves and the broader biotech ecosystem that supports them. It paints a portrait of the crucial roles played by academic research, venture capital, contract research organizations, the capital markets, and pharmaceutical companies, demonstrating how a supportive environment enabled the entrepreneurial biotech industry to create novel medicines with unprecedented efficiency. In doing so, it also offers insights for any industry seeking to innovate in uncertain and ambiguous conditions.
Book Synopsis From Breakthrough to Blockbuster by : Donald L. Drakeman
Download or read book From Breakthrough to Blockbuster written by Donald L. Drakeman and published by Oxford University Press. This book was released on 2022-02-14 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Financial Times Business Top Title March 2022 How could a large collection of small companies, most with fewer than 50 employees, rise to compete with Big Pharma, one of the world's most breathtakingly expensive and highly regulated industries? Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources. Biotech companies have met the challenge by creating nearly 40% more of the most important treatments for previously unmet medical needs. Moreover, they have done so with much lower overall costs. From Breakthrough to Blockbuster: The Business of Biotechnology focuses on both the companies themselves and the broader biotech ecosystem that supports them. It paints a portrait of the crucial roles played by academic research, venture capital, contract research organizations, the capital markets, and pharmaceutical companies, demonstrating how a supportive environment enabled the entrepreneurial biotech industry to create novel medicines with unprecedented efficiency. In doing so, it also offers insights for any industry seeking to innovate in uncertain and ambiguous conditions.
Download or read book British Medical Journal written by and published by . This book was released on 1903 with total page 1792 pages. Available in PDF, EPUB and Kindle. Book excerpt:
